Best TWAS P=2.71e-10 · Best GWAS P=2.5e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | TSKU | 0.09 | 0.03 | blup | 54 | 0.07 | 0.00075 | -4.2 | 6.2 | 4.4e-10 | -0.84 | 0.01 | 0.85 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | TSKU | 0.06 | 0.03 | lasso | 2 | 0.02 | 0.00525 | -6.3 | -6.3 | 2.7e-10 | 1.00 | 0.00 | 0.95 | TRUE |