[Hub]/) : Traits : BMI : ← →

chr12:89,060,567-90,682,621

Best TWAS P=7.48e-12 · Best GWAS P=7.31e-16 conditioned to 4.36e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous POC1B 0.12 0.08 lasso 9 0.09 1.7e-07 5.80 -6.1 1.2e-09 -0.37 0.98 0.01 FALSE
2 GTEx Adrenal Gland RP11-981P6.1 0.33 0.29 lasso 3 0.19 2.2e-07 5.80 6.5 8.4e-11 0.30 0.99 0.00 FALSE
3 GTEx Artery Tibial POC1B 0.13 0.06 enet 29 0.06 1.7e-05 5.90 -6.8 7.5e-12 -0.42 0.39 0.44 TRUE
4 GTEx Artery Tibial RP11-981P6.1 0.07 0.06 lasso 1 0.03 1.3e-03 5.37 5.4 7.8e-08 0.34 0.43 0.30 FALSE
5 GTEx Colon Sigmoid RP11-981P6.1 0.19 0.12 lasso 4 0.11 9.7e-05 5.80 5.3 9.2e-08 0.32 0.32 0.06 FALSE
6 GTEx Colon Transverse RP11-981P6.1 0.14 0.05 enet 26 0.05 1.9e-03 5.91 5.8 5.2e-09 0.28 0.31 0.25 FALSE
7 GTEx Esophagus Muscularis RP11-981P6.1 0.18 0.10 lasso 3 0.06 2.9e-04 5.80 5.7 1.4e-08 0.32 0.86 0.06 FALSE
8 GTEx Liver DUSP6 0.27 -0.01 enet 32 0.00 2.7e-01 0.38 -5.3 1.1e-07 -0.33 0.03 0.32 TRUE
9 GTEx Nerve Tibial POC1B 0.30 0.18 lasso 6 0.22 1.0e-15 -4.85 -6.3 3.2e-10 -0.30 1.00 0.00 FALSE
10 GTEx Spleen RP11-981P6.1 0.28 0.18 lasso 13 0.14 2.1e-04 5.37 6.0 2.2e-09 0.35 0.36 0.17 FALSE
11 GTEx Thyroid RP11-981P6.1 0.24 0.25 lasso 5 0.26 3.9e-20 5.80 5.9 3.4e-09 0.35 1.00 0.00 FALSE
12 METSIM Adipose POC1B 0.07 0.03 bslmm 381 0.03 5.2e-05 5.91 -5.2 2.0e-07 -0.39 0.92 0.00 FALSE