[Hub]/) : Traits : BMI : ← →

chr12:69,045,442-70,476,863

Best TWAS P=1.45e-08 · Best GWAS P=3.04e-12 conditioned to 2.9e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LYZ 0.15 0.08 lasso 3 0.09 5.4e-08 5.0 5.2 2.3e-07 0.45 0.99 0.01 FALSE
2 GTEx Brain Cortex YEATS4 0.22 0.11 enet 18 0.09 1.8e-03 -4.9 5.4 5.4e-08 0.56 0.27 0.28 FALSE
3 GTEx Heart Atrial Appendage LYZ 0.20 0.20 enet 17 0.16 1.7e-07 -4.8 5.1 2.9e-07 0.54 0.86 0.13 FALSE
4 GTEx Skin Sun Exposed Lower leg LYZ 0.09 0.10 enet 13 0.10 8.0e-09 -4.2 5.2 2.4e-07 0.44 1.00 0.00 FALSE
5 GTEx Spleen LYZ 0.30 0.14 enet 25 0.09 2.5e-03 -3.8 5.1 2.9e-07 0.57 0.19 0.49 FALSE
6 GTEx Spleen RP11-1143G9.4 0.29 0.09 lasso 11 0.09 2.9e-03 -3.8 5.2 2.6e-07 0.55 0.16 0.50 FALSE
7 GTEx Testis YEATS4 0.56 0.41 enet 35 0.60 7.1e-33 5.7 5.5 4.2e-08 0.63 0.69 0.31 FALSE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma LYZ 0.06 0.03 blup 42 0.05 6.9e-05 -4.2 5.7 1.5e-08 0.53 0.67 0.30 TRUE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LYZ 0.13 0.16 enet 8 0.17 2.6e-18 5.0 5.2 1.7e-07 0.52 0.97 0.03 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma LYZ 0.06 0.06 enet 6 0.06 7.5e-08 5.0 5.5 3.5e-08 0.59 0.15 0.85 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma LYZ 0.10 0.08 enet 8 0.10 2.4e-11 -4.8 5.4 6.9e-08 0.55 0.98 0.02 FALSE
12 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma LYZ 0.16 0.12 enet 13 0.13 2.3e-04 -4.2 5.3 1.1e-07 0.42 0.19 0.35 FALSE