Best TWAS P=9.59e-21 · Best GWAS P=1.2e-25 conditioned to 0.00141
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | BTBD7 | 0.04 | 0.04 | lasso | 2 | 0.03 | 1.8e-04 | -6.8 | 7.2 | 8.2e-13 | -0.43 | 0.92 | 0.01 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | BTBD7 | 0.16 | 0.01 | lasso | 8 | 0.04 | 3.6e-04 | -8.7 | 8.5 | 2.3e-17 | -0.58 | 0.11 | 0.87 | FALSE |
| 3 | GTEx | Esophagus Mucosa | BTBD7 | 0.16 | 0.02 | lasso | 5 | 0.05 | 3.5e-04 | -4.6 | 5.8 | 5.4e-09 | -0.55 | 0.11 | 0.51 | FALSE |
| 4 | GTEx | Testis | BTBD7 | 0.19 | 0.00 | enet | 45 | 0.01 | 9.5e-02 | -6.7 | 7.3 | 3.5e-13 | -0.56 | 0.04 | 0.88 | FALSE |
| 5 | NTR | Blood | BTBD7 | 0.02 | 0.03 | lasso | 2 | 0.02 | 6.1e-08 | -6.8 | 7.4 | 1.1e-13 | -0.47 | 1.00 | 0.00 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | BTBD7 | 0.04 | 0.01 | enet | 10 | 0.03 | 2.6e-04 | -2.0 | 5.6 | 2.8e-08 | -0.48 | 0.12 | 0.06 | FALSE |
| 7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C14orf142 | 0.11 | 0.04 | enet | 7 | 0.05 | 7.2e-07 | 3.7 | -5.5 | 4.9e-08 | 0.22 | 0.51 | 0.07 | TRUE |
| 8 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | BTBD7 | 0.02 | 0.01 | blup | 72 | 0.02 | 6.8e-03 | -10.0 | 9.3 | 9.6e-21 | -0.80 | 0.01 | 0.92 | TRUE |
| 9 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | BTBD7 | 0.11 | 0.03 | blup | 72 | 0.02 | 8.0e-02 | -8.7 | 8.1 | 7.5e-16 | -0.56 | 0.08 | 0.10 | FALSE |