[Hub]/) : Traits : BMI : ← →

chr15:58,185,362-60,086,249

Best TWAS P=3.8e-09 · Best GWAS P=3.03e-09 conditioned to 0.189

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RNF111 0.07 0.00 blup 466 0.03 1.6e-04 4.8 5.7 1.4e-08 0.51 0.28 0.37 FALSE
2 GTEx Adipose Subcutaneous ADAM10 0.06 0.02 lasso 3 0.02 1.3e-02 5.4 5.5 4.2e-08 0.97 0.06 0.92 FALSE
3 GTEx Cells Transformed fibroblasts RP11-50C13.1 0.12 0.05 lasso 4 0.05 2.0e-04 5.4 -5.3 9.4e-08 -0.91 0.05 0.94 FALSE
4 GTEx Esophagus Mucosa ADAM10 0.17 0.06 lasso 11 0.10 3.2e-07 5.6 5.1 2.9e-07 0.84 0.04 0.96 FALSE
5 GTEx Esophagus Muscularis ADAM10 0.11 0.03 lasso 5 0.03 8.6e-03 4.8 5.4 6.0e-08 0.83 0.06 0.90 FALSE
6 GTEx Heart Atrial Appendage ADAM10 0.09 0.01 lasso 2 0.01 1.8e-01 5.7 5.8 7.5e-09 0.90 0.03 0.93 FALSE
7 GTEx Skin Sun Exposed Lower leg ADAM10 0.09 0.05 lasso 7 0.02 5.3e-03 5.4 5.3 1.3e-07 0.96 0.05 0.94 FALSE
8 GTEx Thyroid ADAM10 0.13 0.00 lasso 3 0.00 1.6e-01 5.5 5.3 1.4e-07 0.82 0.04 0.84 FALSE
9 METSIM Adipose ADAM10 0.06 0.06 lasso 3 0.05 8.2e-08 5.8 5.9 3.8e-09 0.92 0.02 0.98 TRUE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HSP90AB4P 0.02 0.01 blup 31 0.01 2.5e-02 5.6 -5.7 1.5e-08 -0.94 0.01 0.80 FALSE