Best TWAS P=9.11e-11 · Best GWAS P=8.31e-13 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | PEPD | 0.37 | 0.32 | enet | 20 | 0.39 | 9.5e-28 | 4.5 | 5.8 | 8.4e-09 | -0.06 | 0.87 | 0.13 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PEPD | 0.06 | 0.01 | blup | 114 | 0.04 | 2.6e-04 | 6.1 | 5.8 | 8.3e-09 | -0.03 | 0.01 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | PEPD | 0.13 | 0.06 | blup | 113 | 0.10 | 1.2e-06 | 3.9 | 6.1 | 8.7e-10 | -0.07 | 0.02 | 0.97 | TRUE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | PEPD | 0.16 | 0.07 | lasso | 3 | 0.05 | 3.1e-03 | 6.2 | 6.0 | 1.4e-09 | -0.06 | 0.01 | 0.95 | FALSE |
| 5 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | KCTD15 | 0.25 | 0.05 | lasso | 4 | 0.04 | 3.3e-02 | -7.1 | -6.5 | 9.1e-11 | 0.96 | 0.00 | 0.93 | TRUE |