Best TWAS P=4.9e-15 · Best GWAS P=7.67e-44 conditioned to 1.02e-24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | FOSB | 0.28 | 0.00 | lasso | 4 | 0.00 | 0.41300 | -6.2 | -7.8 | 4.9e-15 | 0.44 | 0.88 | 0.12 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SNRPD2 | 0.03 | 0.02 | blup | 36 | 0.02 | 0.00015 | 4.0 | -6.6 | 4.5e-11 | 0.39 | 0.79 | 0.04 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | CKM | 0.13 | 0.00 | blup | 38 | 0.05 | 0.00222 | -5.2 | -5.6 | 2.7e-08 | 0.05 | 0.00 | 0.59 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | APOC1P1 | 0.05 | 0.03 | blup | 37 | 0.03 | 0.00052 | 2.9 | -5.8 | 9.1e-09 | -0.04 | 0.17 | 0.04 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SNRPD2 | 0.13 | 0.02 | blup | 36 | 0.03 | 0.01310 | 2.6 | -5.2 | 2.4e-07 | 0.45 | 0.01 | 0.15 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | SNRPD2 | 0.04 | 0.03 | enet | 7 | 0.03 | 0.00026 | 4.2 | -5.6 | 2.7e-08 | 0.36 | 0.41 | 0.09 | TRUE |