Best TWAS P=8.94e-08 · Best GWAS P=3.22e-08 conditioned to 0.134
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | NSFL1C | 0.17 | 0.06 | lasso | 6 | 0.02 | 2.3e-02 | -5.2 | 5.3 | 1.1e-07 | -0.88 | 0.02 | 0.95 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NSFL1C | 0.10 | 0.06 | lasso | 9 | 0.06 | 4.6e-08 | -5.1 | -5.3 | 1.1e-07 | 0.90 | 0.03 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NSFL1C | 0.06 | 0.05 | lasso | 3 | 0.04 | 2.1e-05 | -5.2 | 5.3 | 8.9e-08 | -0.93 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NSFL1C | 0.09 | 0.05 | lasso | 6 | 0.03 | 6.7e-04 | -5.0 | 5.3 | 1.3e-07 | -0.90 | 0.02 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | NSFL1C | 0.05 | 0.04 | lasso | 8 | 0.05 | 1.2e-05 | -5.1 | 5.3 | 1.0e-07 | -0.88 | 0.03 | 0.97 | FALSE |