Hub : Genes

NSFL1C

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0700 0.0240 1.2e-03 0.049 0.027 0.069 NA 0.051 1.3e-06 2.6e-04 8.7e-09 NA 8.1e-07
2 GTEx Adipose Subcutaneous 0.0900 0.0330 5.0e-03 0.035 NA 0.005 NA 0.012 7.3e-04 NA 1.1e-01 NA 3.5e-02
3 GTEx Artery Tibial 0.1654 0.0412 1.7e-06 0.179 NA 0.152 NA 0.048 5.2e-14 NA 5.9e-12 NA 1.1e-04
4 GTEx Brain Cerebellar Hemisphere 0.3930 0.1150 3.9e-03 -0.009 NA -0.007 NA 0.004 6.4e-01 NA 5.3e-01 NA 2.5e-01
5 GTEx Cells Transformed fibroblasts 0.1350 0.0570 4.5e-03 0.008 NA 0.010 NA 0.009 7.0e-02 NA 5.5e-02 NA 6.4e-02
6 GTEx Colon Sigmoid 0.2040 0.0840 7.9e-03 0.070 NA 0.083 NA 0.107 1.8e-03 NA 7.3e-04 NA 1.3e-04
7 GTEx Colon Transverse 0.1670 0.0570 2.0e-03 0.060 NA 0.001 NA 0.025 8.0e-04 NA 2.7e-01 NA 2.3e-02
8 GTEx Esophagus Muscularis 0.2670 0.0610 3.4e-07 0.238 NA 0.187 NA 0.222 1.3e-14 NA 1.5e-11 NA 1.3e-13
9 GTEx Heart Atrial Appendage 0.2010 0.0650 2.9e-03 -0.002 NA -0.006 NA -0.002 4.1e-01 NA 7.5e-01 NA 4.1e-01
10 GTEx Lung 0.2150 0.0573 1.2e-04 0.047 NA 0.074 NA 0.081 1.6e-04 NA 2.4e-06 NA 9.2e-07
11 GTEx Muscle Skeletal 0.0998 0.0324 4.9e-04 0.073 NA 0.048 NA 0.064 1.1e-07 NA 1.6e-05 NA 6.4e-07
12 GTEx Nerve Tibial 0.1463 0.0440 1.9e-04 0.078 NA 0.056 NA 0.066 3.6e-06 NA 8.1e-05 NA 1.9e-05
13 GTEx Skin Sun Exposed Lower leg 0.1070 0.0410 5.2e-03 0.000 NA -0.003 NA -0.003 2.9e-01 NA 6.2e-01 NA 7.1e-01
14 GTEx Stomach 0.1400 0.0580 6.5e-03 0.010 NA -0.006 NA 0.003 9.9e-02 NA 8.0e-01 NA 2.3e-01
15 GTEx Testis 0.4210 0.0740 2.1e-07 0.129 NA 0.156 NA 0.038 2.6e-06 NA 1.9e-07 NA 8.1e-03
16 GTEx Thyroid 0.0820 0.0340 9.5e-03 0.066 NA 0.052 NA 0.023 8.9e-06 NA 7.9e-05 NA 6.4e-03
17 GTEx Whole Blood 0.1510 0.0410 1.3e-04 0.058 NA 0.123 NA 0.109 4.2e-06 NA 2.2e-11 NA 3.3e-10
18 METSIM Adipose 0.0852 0.0242 3.6e-05 0.082 0.048 0.067 0.078 0.071 2.6e-12 1.0e-07 3.0e-10 9.2e-12 8.1e-11
19 NTR Blood 0.0577 0.0145 3.5e-07 0.025 0.021 0.031 0.025 0.028 1.6e-08 1.2e-07 2.6e-10 1.3e-08 1.3e-09
20 ROSMAP Brain Pre-frontal Cortex 0.1020 0.0256 2.6e-06 0.061 0.040 0.055 0.057 0.059 2.9e-08 6.0e-06 1.4e-07 6.9e-08 4.6e-08
21 YFS Blood 0.3719 0.0277 0.0e+00 0.403 0.487 0.529 0.516 0.522 1.2e-143 5.3e-185 1.8e-208 4.2e-201 1.1e-204
22 TCGA Breast Invasive Carcinoma 0.0763 0.0301 7.6e-06 0.004 0.017 0.012 NA 0.014 4.3e-02 1.4e-04 1.3e-03 NA 6.4e-04
23 TCGA Colon Adenocarcinoma 0.2040 0.0710 2.7e-04 0.095 0.045 0.065 NA 0.080 4.1e-06 1.2e-03 1.3e-04 NA 2.4e-05
24 TCGA Kidney Renal Clear Cell Carcinoma 0.0757 0.0279 3.1e-07 0.035 0.045 0.051 NA 0.048 7.6e-05 7.9e-06 1.9e-06 NA 4.2e-06
25 TCGA Brain Lower Grade Glioma 0.0633 0.0326 4.5e-05 0.049 0.035 0.030 NA 0.040 2.6e-06 6.4e-05 2.1e-04 NA 2.0e-05
26 TCGA Lung Adenocarcinoma 0.0348 0.0199 4.3e-03 0.017 0.008 0.001 NA 0.003 4.0e-03 3.4e-02 2.1e-01 NA 1.4e-01
27 TCGA Lung Squamous Cell Carcinoma 0.0878 0.0315 3.6e-06 0.016 0.029 0.019 NA 0.014 5.6e-03 2.4e-04 2.5e-03 NA 7.8e-03
28 TCGA Prostate Adenocarcinoma 0.0885 0.0400 4.1e-05 0.046 0.025 0.013 NA 0.027 1.4e-05 9.9e-04 1.5e-02 NA 6.7e-04
29 TCGA Stomach Adenocarcinoma 0.0920 0.0510 2.3e-03 0.002 0.021 0.024 NA 0.014 2.4e-01 1.0e-02 6.8e-03 NA 3.1e-02
30 TCGA Thyroid Carcinoma 0.0510 0.0220 4.3e-05 0.041 0.044 0.043 NA 0.050 6.8e-05 3.8e-05 5.1e-05 NA 1.2e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Bipolar Disorder (2018) 0.3 0.4 1.3 0.1 -0.6 -0.5 -1.1 -0.9 -0.3 -0.7 -0.6 -0.3 0.6 -0.5 -0.7 -0.2 0.4 -0.4 -0.8 -0.1 0.4 0.7 0.3 -0.7 -1.0 -0.7 -1.0 -0.2 -0.9 -1.1 -0.8 -0.5 -0.7
Bipolar Disorder or Schizophrenia 0.7 1.8 4.7 -0.7 1.0 1.4 -1.1 0.8 1.8 1.1 1.4 1.9 0.2 1.4 1.0 1.7 1.9 1.5 1.2 1.2 0.7 0.7 -0.8 1.0 2.2 2.0 1.0 1.0 1.7 1.8 1.0 1.7 0.4
Depressed Affect (Nagel 2018) 0.3 0.6 6.2 0.2 0.0 -0.4 -1.8 -0.4 -0.7 -0.6 -0.5 -1.3 -2.5 -0.5 0.2 -0.6 0.0 -0.8 -0.2 -1.1 -0.5 -0.9 -0.3 -0.6 -0.1 -0.0 -0.7 -0.1 -0.4 -0.9 0.1 -0.3 0.2
Depression (Nagel 2018) 1.8 2.7 6.7 1.9 -0.9 -1.5 -0.3 -2.3 -2.0 -1.7 -1.7 -2.6 -2.5 -1.7 -0.8 -1.9 -1.5 -1.9 -1.1 -2.3 -1.3 -2.1 0.3 -1.9 -1.1 0.3 -1.6 -0.8 -1.8 -2.4 -0.8 -0.7 -0.5
Intelligence (Savage-Jansen 2018) 1.0 3.1 7.1 -2.2 2.0 1.3 -0.8 1.3 1.4 2.0 1.1 1.6 1.8 1.3 1.9 1.4 1.6 0.3 1.7 1.5 2.7 0.8 -2.5 2.5 1.5 0.9 2.0 2.4 1.3 1.0 2.1 1.7 2.7
Neuroticism (Nagel 2018) 0.2 0.4 3.2 -0.2 -0.0 -0.2 -1.5 -0.1 -0.5 -0.8 -0.1 -0.9 -1.8 -0.4 0.1 -0.5 0.2 -0.3 0.2 0.3 0.7 1.2 -0.4 0.1 0.2 -0.2 -0.8 -0.0 -0.4 -0.7 -0.1 -0.7 -0.2
Schizophrenia (2018) 2.1 4.4 13.2 -1.0 1.8 2.2 -0.6 1.8 2.5 1.9 2.3 2.7 -0.2 2.2 1.9 2.4 2.1 2.2 2.2 1.6 0.6 0.3 -1.3 1.9 3.6 3.1 2.1 1.4 3.0 3.2 1.9 2.6 1.1
Schizophrenia vs Biploar Disorder 4.8 6.3 17.1 -1.3 2.5 2.7 -1.4 1.7 2.4 2.9 2.7 2.9 -1.1 2.7 2.7 2.3 2.5 2.3 2.4 -0.3 -0.1 -2.4 -2.0 1.6 3.7 3.7 3.1 2.5 3.0 2.7 2.9 4.1 2.1
Worry (Nagel 2018) 0.5 1.0 5.5 0.6 -1.1 -0.9 0.6 -0.7 -0.6 -1.8 -0.7 -1.5 -2.3 -0.7 -1.0 -0.6 -0.7 -0.4 -0.6 -0.4 -0.5 0.8 1.0 -1.0 0.1 0.4 -1.7 -1.3 -1.0 -0.7 -1.2 -0.7 -1.5
Alzheimer’s Disease (in mother) 0.8 0.9 2.8 0.4 -1.5 -0.9 0.5 -0.5 -0.8 -1.4 -0.8 -1.1 -0.4 -0.9 -1.2 -0.8 -1.0 -0.4 -1.1 0.1 -0.5 0.0 1.6 -1.1 -0.1 0.5 -1.6 -1.4 -0.6 -0.1 -1.2 0.0 -1.7
Alzheimer’s Disease (in father) 0.5 0.6 3.3 0.2 -0.5 0.5 0.1 0.5 0.7 -0.8 0.5 -0.3 0.5 0.6 -0.6 0.7 -0.5 1.1 -0.2 1.2 0.5 0.8 0.9 -0.3 -0.1 -0.7 -0.9 -1.0 -0.3 0.4 -1.1 -1.2 -1.8
Alzheimer’s Disease (including proxy) 1.0 1.5 6.9 0.5 -1.7 -0.6 0.2 -0.2 -0.5 -1.8 -0.6 -1.3 -1.0 -0.5 -1.4 -0.5 -2.6 0.3 -1.1 0.1 -0.6 0.0 2.2 -1.5 -0.3 0.6 -2.0 -1.6 -0.5 0.1 -1.7 -0.6 -2.6
Crohns Disease (2017) 0.3 0.7 4.3 -0.6 1.3 0.9 -2.1 0.1 0.5 0.3 0.6 -0.3 -0.3 0.6 1.3 0.4 0.1 0.1 0.9 -0.2 0.2 -1.2 -1.2 0.8 1.0 -0.3 0.2 1.0 0.7 1.1 1.2 0.4 1.2
Irritable Bowel Disease (IBD) 0.3 0.7 3.4 -0.4 1.0 0.3 -1.8 0.1 0.0 0.2 0.0 -0.7 -1.1 0.0 0.8 -0.1 -0.3 -0.7 0.5 -1.0 -0.3 -1.8 -1.1 0.3 1.2 0.3 0.0 1.2 0.7 0.8 0.9 0.9 1.4
Ulcerative Colitis (UC) 0.2 0.5 2.5 0.1 0.0 -0.5 -0.7 0.1 -0.8 -0.2 -0.7 -0.8 -1.6 -0.7 -0.3 -0.8 -0.4 -1.1 -0.3 -1.2 -0.8 -1.3 -0.3 -0.5 0.6 0.6 -0.5 0.5 0.1 -0.0 -0.1 0.6 0.6
Major Depression (MDD) 1.1 1.3 4.1 0.7 -0.9 -1.3 -0.7 -1.8 -1.7 -1.1 -1.1 -1.8 -1.1 -1.0 -1.0 -1.8 -1.1 -1.1 -0.6 -0.1 0.5 -0.0 0.1 -0.6 -1.4 -0.8 -1.5 -0.9 -1.6 -2.0 -1.1 -0.7 -0.7
Reaction Time 0.1 0.2 2.2 -0.4 0.1 0.0 1.0 0.1 -0.2 0.3 0.1 -0.1 0.4 0.0 0.3 -0.2 -0.6 0.1 0.4 0.4 0.6 1.5 -0.3 0.3 -0.4 -0.2 0.4 0.3 0.0 -0.4 0.3 -0.1 0.2
Verbal and Numeric Reasoning (VNR) 1.6 3.8 11.1 -2.0 2.3 1.3 -0.1 1.5 1.7 2.3 1.3 1.6 1.9 1.3 2.1 1.7 1.9 0.3 1.9 2.0 3.3 0.6 -2.7 2.8 1.8 1.0 2.6 2.7 1.3 0.7 2.4 1.9 2.9
Breast Cancer 0.4 1.0 4.1 -1.8 0.7 0.1 0.6 1.0 0.3 0.9 0.0 0.6 0.8 -0.1 0.7 0.3 0.8 -0.5 0.4 1.2 2.0 0.8 -0.9 1.2 1.7 1.3 1.1 1.1 0.6 0.5 1.0 1.3 1.4
Ovarian Cancer 0.3 0.4 2.0 -0.8 0.7 0.9 -1.2 0.5 0.2 0.5 1.0 0.5 0.3 1.0 0.6 0.2 0.3 0.9 0.9 -0.7 -0.5 -1.4 -0.6 0.0 -0.1 0.0 0.8 0.3 0.1 -0.2 0.5 0.0 0.2
Prostate Cancer 0.1 0.1 1.3 -0.4 0.1 0.3 -0.7 0.1 -0.6 -0.0 0.1 -0.1 -1.1 0.1 -0.2 -0.5 0.6 0.1 -0.1 -0.3 -0.3 0.2 -0.1 -0.1 0.5 -0.1 -0.2 -0.4 0.1 -0.0 -0.3 0.0 0.1
Age at First Birth 0.3 0.5 1.8 -0.6 0.7 0.9 0.0 1.2 -0.0 1.2 0.9 0.9 -0.7 0.7 0.6 -0.1 -0.5 0.7 0.8 -0.5 -0.4 -0.2 -0.6 0.5 0.2 -0.6 0.5 0.5 1.3 0.3 0.6 0.8 0.6
Bipolar Disorder (2011) 0.7 0.6 4.2 -0.9 0.4 0.9 -1.1 0.7 0.9 0.7 0.8 0.6 1.4 0.8 0.4 0.9 0.5 1.0 0.2 0.7 0.2 0.6 -0.3 0.7 -1.0 -2.1 0.1 0.8 0.7 0.0 0.2 -0.5 0.1
Body Mass Index (BMI) (2010) 1.3 1.8 8.0 -1.6 2.0 1.5 -2.8 0.0 0.4 1.6 1.2 0.1 0.3 1.1 2.0 0.4 -0.0 0.2 1.3 0.1 1.4 -0.1 -2.2 1.5 1.3 0.2 1.8 1.8 0.8 -0.0 2.0 0.6 2.2
Coronary Artery Disease (CAD) 0.8 0.9 5.5 1.1 -0.1 0.0 0.5 -1.2 -1.1 -0.3 0.1 -0.5 -1.1 0.1 0.1 -1.2 -0.7 0.2 0.7 -2.0 -2.3 -2.3 0.6 -1.2 -0.7 -0.7 -0.2 -0.8 -0.1 -0.3 0.0 -0.8 -0.2
Crohns Disease (2012) 0.8 1.2 5.3 -1.0 2.0 0.7 -1.7 -0.6 0.1 0.7 0.4 -0.7 -0.6 0.3 1.8 0.0 -0.2 -0.8 1.3 -0.9 0.2 -1.3 -2.3 1.0 0.3 -0.7 1.0 1.3 0.2 -0.3 1.8 -0.2 2.3
Mean Putamen Volume 1.4 1.5 8.0 -2.1 1.4 0.0 -2.5 0.5 -0.5 1.8 0.1 0.3 -0.6 -0.0 1.3 -0.5 -0.2 -1.0 0.9 -0.5 0.8 -1.1 -1.8 1.2 1.2 -0.1 1.2 1.3 0.9 0.2 1.8 1.5 2.8
Fasting Glucose 0.1 0.1 1.3 0.3 0.1 -0.3 -0.2 -1.1 0.1 -0.5 -0.4 -0.4 -0.1 -0.3 0.0 -0.0 0.1 -0.5 -0.1 -0.0 0.1 -0.7 -0.2 -0.2 -0.1 0.4 -0.2 0.2 -0.4 -0.4 -0.0 -0.1 0.0
HbA1C 1.7 1.9 4.4 -0.4 1.8 1.9 -1.9 -0.3 1.2 1.5 2.1 1.1 0.4 2.1 2.0 0.8 0.9 1.8 1.5 0.1 -0.1 -1.1 -1.8 1.1 0.9 1.5 2.1 0.9 1.4 0.8 1.7 1.2 0.8
HDL Cholesterol 0.3 0.5 1.8 0.2 -0.6 -0.9 -0.1 -0.4 -0.6 -0.4 -1.0 -0.5 -0.6 -0.8 -0.9 -0.6 -1.0 -1.0 -0.9 -0.3 -0.0 -0.2 0.3 -0.3 -1.1 -1.3 -0.6 -0.1 -0.7 -0.9 -0.7 -0.7 -0.1
LDL Cholesterol 0.1 0.2 1.2 -0.5 0.3 0.2 -0.4 -0.0 -0.4 0.2 0.5 0.0 -0.1 0.2 0.3 -0.3 -0.3 0.3 0.1 -0.5 0.1 0.1 -0.2 -0.2 -0.8 -0.5 0.2 -0.5 -0.7 -1.1 0.1 -0.5 -0.2
Lupus 0.5 0.8 6.7 1.3 -0.8 0.1 2.6 -0.2 1.0 -0.6 0.2 0.0 -0.5 0.2 -0.8 1.0 0.9 1.0 -0.5 0.5 -1.1 -0.1 0.6 -0.4 -0.3 0.6 -0.4 -1.3 0.0 1.2 -1.0 -0.0 -1.5
Neuroticism (2016) 0.2 0.3 1.1 1.0 -0.2 -0.6 -1.0 -0.3 -1.0 -0.0 -0.7 -0.4 -0.4 -0.7 0.1 -1.0 -0.3 -0.9 -0.4 0.0 0.8 0.8 -0.0 -0.0 0.5 0.6 -0.1 0.6 0.2 -0.2 0.4 0.6 0.7
Primary Biliary Cirrhosis 2.0 2.9 7.4 -2.7 2.2 1.3 -2.5 0.5 1.3 2.2 1.3 1.3 2.1 1.2 1.7 1.2 1.0 0.4 1.6 1.1 1.8 1.5 -2.6 2.4 0.7 -0.6 2.0 2.7 1.2 0.7 1.8 0.7 2.5
Rheumatoid Arthritis 0.3 0.4 2.7 0.7 0.2 0.7 -0.4 -0.4 0.1 -0.5 0.7 -0.0 0.2 0.7 0.2 0.1 0.1 0.8 0.2 0.7 0.5 0.8 -0.1 0.2 -1.1 -1.1 0.2 -0.6 -0.8 -1.3 -0.3 -1.6 -0.7
Schizophrenia (2014) 2.6 5.7 14.6 -0.6 2.2 2.4 -1.2 1.7 2.7 2.3 2.5 3.0 0.9 2.5 2.3 2.7 3.3 2.4 2.3 1.7 1.3 0.1 -1.9 2.2 3.8 3.4 2.4 2.3 3.0 2.8 2.3 3.4 1.4
Triglycerides 0.7 1.1 2.6 -0.8 1.4 0.9 -0.4 1.2 1.4 1.1 1.1 1.1 1.5 1.1 1.3 1.4 1.6 0.9 1.1 0.8 0.8 0.2 -1.2 1.0 0.8 0.7 1.4 1.0 0.7 0.7 1.2 0.8 1.0
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.7 0.4 0.1 0.1 -0.8 0.0 0.4 0.5 0.4 0.3 -0.5 0.3 -0.0 0.2 0.0 0.3 -0.0 -0.1 -0.4 0.1 -0.1 -0.1 -0.1 -0.6 -0.0 -0.3 0.4 0.4 -0.2 0.1 -0.3
Ulcerative Colitis 0.4 0.5 3.6 0.5 0.1 -0.3 0.1 -0.4 -0.8 0.3 -0.5 -0.4 -1.5 -0.4 -0.1 -0.8 -0.2 -0.8 0.4 -1.9 -1.3 -1.8 -0.3 -0.8 0.3 0.2 -0.1 0.1 0.1 -0.3 0.2 0.9 0.8
Blood Eosinophil Count 0.4 3.5 25.6 -0.1 0.2 -0.5 -1.7 -1.0 -1.3 0.0 -0.5 -1.0 1.9 -0.5 -0.1 -1.3 -1.0 -1.0 -0.7 2.2 3.7 5.1 -0.8 1.4 -1.3 -4.2 0.0 -0.3 -1.3 -2.7 -0.4 -3.5 0.5
Blood Platelet Count 0.5 5.6 46.9 -2.3 2.3 2.6 -6.8 3.2 2.5 2.1 2.6 2.5 1.9 2.5 2.6 2.5 0.9 2.1 0.9 1.0 0.2 0.5 -2.0 2.2 -1.1 -2.2 2.8 2.2 1.7 0.5 2.2 -1.0 1.7
Blood Red Count 0.1 0.5 2.5 -0.5 -0.1 0.3 1.1 -0.0 0.4 -0.1 0.3 0.8 1.3 0.3 -0.2 0.5 -0.4 0.7 0.2 1.0 0.6 1.0 0.4 0.3 -1.5 -1.6 -0.5 -0.0 -0.3 0.5 -0.5 -0.9 -0.7
Blood White Count 0.2 1.4 15.7 -1.4 0.5 -0.5 -4.0 -0.3 0.3 0.5 -0.6 0.1 0.8 -0.5 0.4 0.3 0.1 -1.2 -0.2 -1.0 0.3 0.7 -1.0 0.2 -1.8 -2.1 0.2 1.3 -0.4 -2.5 0.6 -0.9 1.4
Heel T-Score 0.1 1.0 7.2 0.2 -0.4 -0.2 0.8 -1.1 -0.2 -0.7 0.2 -1.0 -2.7 0.2 -0.2 -0.2 -0.0 0.7 0.4 -1.2 -2.0 -2.1 1.1 -1.1 0.8 0.2 -1.2 -0.7 0.6 0.8 -0.5 0.2 -1.1
BMI 2.7 15.5 28.6 -4.6 4.9 4.0 -4.3 3.3 3.3 5.3 3.7 4.2 1.1 3.7 4.9 3.4 4.1 2.2 4.3 1.2 2.2 0.5 -5.3 4.4 3.1 1.1 4.9 5.3 4.2 2.9 5.3 3.7 5.3
Height 0.1 1.9 12.5 1.3 -1.2 -0.3 1.2 0.2 0.0 -0.8 -0.4 0.4 3.5 -0.4 -1.0 0.1 -0.3 0.1 -0.6 3.2 2.8 3.3 0.5 0.8 -0.4 1.2 -0.9 -0.9 -1.0 0.2 -1.1 -0.3 -1.4
Waist Hip Ratio (WHR) 1.1 5.0 12.5 -1.3 2.1 1.7 -3.0 2.2 1.7 2.2 1.9 1.7 2.4 1.8 1.8 1.7 1.5 1.3 2.2 2.6 3.3 1.9 -2.3 2.9 3.5 2.6 1.7 2.5 2.6 2.1 1.9 2.6 1.9
Systolic Blood Pressure 0.1 0.4 2.6 0.2 -0.8 -0.5 0.7 -0.3 -0.1 -0.9 -0.4 -0.4 -0.2 -0.3 -0.6 0.1 -0.7 -0.1 -0.1 -0.1 -0.4 0.0 0.9 -0.8 0.5 1.6 -1.0 -0.7 -0.1 0.5 -0.5 0.4 -1.0
Smoking Status 0.3 0.6 5.2 -0.5 0.4 0.1 -0.9 0.5 0.4 0.5 0.1 0.1 -0.3 -0.0 0.2 0.4 0.8 -0.1 0.0 -1.5 -0.9 -2.3 -0.3 -0.6 1.1 1.4 0.1 0.0 0.2 0.8 0.4 1.7 0.6
Allergy or Eczema 0.6 1.5 6.8 1.0 -1.5 -1.4 -0.9 0.1 -0.7 -1.0 -1.3 -0.3 0.5 -1.3 -1.7 -0.7 0.3 -0.8 -1.5 1.6 1.0 2.6 1.1 0.1 -1.4 -2.2 -1.5 -0.7 -0.6 -0.7 -1.6 -1.4 -1.0
Cardiovascular Disease 2.0 6.7 13.8 -2.9 3.0 2.3 -3.1 1.3 2.5 2.9 2.2 2.3 -0.5 2.2 2.9 2.5 2.3 1.4 2.7 0.3 0.8 -0.3 -3.2 2.3 3.7 3.1 2.7 3.0 2.8 3.3 3.3 3.7 3.0
Hypothyroidism (self reported) 0.7 1.7 7.6 -0.8 1.2 0.8 -0.7 1.8 1.1 1.3 0.7 1.0 -0.1 0.6 0.9 1.1 0.8 0.1 0.7 0.8 1.6 0.1 -1.0 1.3 2.8 2.2 0.9 1.9 1.6 1.2 1.2 2.6 1.4
Respiratory disease 0.5 1.1 5.7 0.4 0.9 0.7 -1.5 0.1 0.6 0.8 0.9 0.4 -0.5 0.9 1.2 0.6 0.4 0.7 1.1 0.2 0.3 -0.2 -1.0 0.9 2.1 2.4 1.1 1.0 1.4 1.3 1.3 1.7 0.7
Type 2 Diabetes (T2D) (2018) 0.4 0.7 3.9 1.4 -0.2 0.1 0.5 -1.2 -0.2 -0.0 -0.0 -0.3 -2.0 -0.0 -0.1 -0.2 0.0 0.2 0.0 -1.5 -1.2 -1.2 0.2 -1.0 1.2 1.6 -0.2 -0.0 0.6 0.3 -0.0 1.3 -0.3
Lung FEV1/FVC ratio 0.4 1.8 9.7 -0.7 1.0 0.5 -1.4 1.5 0.4 1.4 0.4 1.0 -1.0 0.4 0.9 0.4 1.1 0.1 0.5 -2.5 -1.6 -3.1 -0.7 -0.7 1.8 2.0 0.8 1.2 1.1 0.7 1.5 2.7 1.5
Lung FVC 0.3 1.6 8.7 1.3 -1.3 -0.2 3.0 -0.4 0.2 -1.5 -0.1 -0.7 1.0 -0.1 -1.3 0.2 -1.2 0.6 -1.0 0.3 -0.4 0.5 1.7 -1.1 -1.9 -1.1 -1.6 -1.4 -0.9 -1.0 -1.7 -1.9 -2.3
Neuroticism 0.6 1.4 5.5 1.4 -1.0 -0.8 -1.8 -1.4 -1.0 -2.1 -0.9 -2.0 -2.3 -0.9 -0.8 -0.9 -0.6 -0.7 -1.0 -0.4 -0.4 0.7 0.6 -1.0 -0.3 0.3 -2.0 -1.3 -1.1 -0.9 -1.1 -0.9 -1.3
Chronotype (morning person) 0.6 1.3 2.9 -0.2 1.3 1.5 -0.8 1.7 1.2 1.5 1.5 1.3 0.2 1.5 1.3 1.2 0.7 1.3 1.3 0.5 -0.0 -0.4 -0.9 1.2 1.2 0.1 1.3 0.8 1.5 1.6 1.2 1.1 1.0
Hair Pigment 0.0 0.2 2.3 -0.4 0.3 0.3 -0.3 0.4 0.2 -0.2 0.2 -0.2 0.5 0.2 0.2 0.3 -0.0 0.3 -0.1 -0.8 -0.6 -1.5 0.0 -0.6 -0.7 0.6 -0.3 -0.4 -0.3 -0.9 0.2 0.2 -0.2
Tanning 0.1 1.1 5.8 0.4 -0.9 -0.7 2.4 -0.4 -0.4 -1.5 -0.6 -1.3 1.1 -0.6 -0.9 -0.4 -0.9 -0.4 -0.6 0.5 0.1 1.1 0.8 -0.6 -1.6 -0.6 -1.2 -1.4 -1.6 -0.6 -1.2 -1.8 -1.3
Hand grip strength (left) 0.3 0.7 3.7 0.3 -0.8 -0.5 0.4 -0.6 -0.3 -1.0 -0.6 -0.2 1.8 -0.5 -0.6 -0.3 -0.3 -0.3 -0.6 1.5 1.9 1.5 0.4 0.0 -0.7 0.7 -1.3 -0.7 -1.1 -0.3 -0.6 -0.0 -0.8
Number of treatments/medications taken 2.1 3.8 7.6 -1.1 1.9 2.1 -0.9 1.8 2.4 2.8 2.2 2.3 0.2 2.1 2.0 2.4 1.6 1.9 2.3 0.7 0.9 -0.1 -1.9 1.7 2.0 1.3 2.4 2.3 2.4 2.4 2.2 2.5 1.9
Average weekly spirits intake 1.0 1.3 3.6 0.0 -0.8 -1.4 -1.1 -1.1 -1.6 -0.9 -1.2 -1.3 -0.9 -1.3 -1.0 -1.5 -1.9 -1.3 -1.2 -1.4 -1.1 -1.6 1.0 -1.4 -1.0 0.0 -1.2 -0.5 -0.8 -0.9 -0.8 -0.2 -0.3
Sensitivity / hurt feelings 0.1 0.2 1.3 -0.1 0.2 0.3 -0.6 0.7 0.3 -0.1 0.1 0.6 -0.2 0.1 0.5 0.3 1.1 0.1 0.4 0.2 -0.5 0.5 -0.2 0.4 -0.0 0.1 -0.0 0.5 0.8 0.1 0.5 -0.4 0.4
Frequency of depressed mood in last 2 weeks 0.4 0.5 2.0 0.9 0.0 -0.3 -0.5 -1.4 -0.9 -0.8 -0.3 -1.4 -0.7 -0.3 0.1 -0.9 -0.8 -0.6 -0.1 0.2 0.6 0.5 -0.5 0.0 -0.8 -0.5 -0.4 -0.1 -0.8 -1.2 -0.1 -1.3 -0.1
Hearing difficulty/problems: Yes 0.2 0.4 1.8 -0.9 0.5 0.3 -1.3 -0.1 0.2 0.2 0.5 -0.5 0.1 0.5 0.7 0.2 1.2 0.5 0.2 0.4 0.7 -0.4 -0.8 0.7 0.8 0.8 0.5 0.1 -0.1 -0.2 0.5 0.7 0.3
Relative age of first facial hair 0.4 0.8 3.8 -1.1 1.1 -0.2 -1.0 -1.2 -0.4 0.9 -0.1 0.3 -1.1 -0.1 0.9 -0.5 0.3 -0.9 0.6 -0.7 0.3 -0.2 -1.2 0.6 1.2 1.2 1.0 1.3 0.3 0.1 1.2 1.2 2.0
Other serious medical condition/disability diagnosed by doctor 2.2 2.9 5.6 -1.6 2.2 1.9 -1.8 2.0 1.6 2.0 1.6 1.5 -0.1 1.5 2.2 1.6 1.2 0.8 1.7 -0.2 -0.2 -0.0 -2.2 1.7 1.9 1.4 2.0 2.1 2.4 1.3 2.3 1.6 2.2
Ever used hormone-replacement therapy (HRT) 1.1 1.3 5.7 -1.4 1.3 1.7 -0.2 1.4 0.7 1.0 1.6 0.7 -2.4 1.6 0.9 0.7 0.4 1.5 1.6 -0.5 -0.9 -0.9 -1.0 0.6 1.3 -0.1 0.8 0.8 2.0 1.5 0.7 0.2 0.5
Ever had hysterectomy (womb removed) 2.2 2.5 10.1 0.4 -1.6 -1.1 0.3 -0.9 -1.2 -1.2 -0.7 -1.1 -2.4 -0.8 -1.5 -1.2 -3.2 -0.2 -1.3 -2.0 -2.5 -1.3 2.3 -2.2 -2.2 -1.7 -1.6 -1.5 -0.6 -0.6 -1.7 -1.6 -1.9
Systolic blood pressure, automated reading 0.3 0.9 5.4 -0.3 0.4 1.0 0.5 0.8 1.8 0.8 0.8 1.1 0.9 0.9 0.5 1.8 0.2 1.0 1.0 0.1 -0.6 -0.5 0.1 0.2 1.2 1.2 0.4 0.7 1.4 2.3 0.6 1.4 0.1
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.4 1.2 -0.2 0.0 0.3 -0.2 0.6 0.1 0.1 0.3 -0.9 -0.0 -0.2 0.6 0.8 0.4 -0.2 -0.6 -1.2 -0.4 0.4 -0.5 0.4 0.1 0.0 0.2 1.1 0.9 -0.1 0.3 -0.2
Angina 0.8 1.0 3.5 -0.7 0.8 1.1 -0.2 1.6 1.3 1.1 1.2 1.9 -0.3 1.1 0.7 1.3 0.9 1.1 1.0 0.5 -0.2 -0.2 -0.5 0.8 0.9 0.3 1.3 0.8 1.2 1.8 0.8 0.8 0.6
Medication for hormone replacement therapy 0.3 0.3 1.2 0.3 0.2 -0.7 -0.8 -0.5 -0.8 -0.3 -0.5 -0.7 -1.1 -0.5 0.2 -0.9 -0.1 -1.0 0.1 -0.9 -0.2 -0.7 -0.3 -0.2 -0.1 -0.1 -0.4 0.3 -0.1 -1.1 0.3 -0.2 0.7
Vitamin and mineral supplements 0.4 0.5 1.3 -0.3 0.7 1.1 0.6 0.5 0.6 0.7 1.1 0.5 -0.3 1.1 0.7 0.6 -0.1 1.1 0.6 0.8 0.7 1.1 -0.8 0.8 -0.1 -0.4 1.0 0.2 0.3 -0.2 0.4 -0.6 0.1
Supplements: Zinc 0.6 0.7 4.2 0.4 -1.0 -0.7 2.0 0.9 0.4 0.0 -0.7 1.1 0.4 -0.8 -0.8 0.4 1.3 -0.2 -0.3 0.7 0.1 -0.4 0.7 -0.2 0.2 1.9 -0.1 -0.1 0.2 0.9 -0.4 1.7 -0.4
Medication: Co-codamol 0.6 0.7 2.5 -0.9 0.8 0.3 -0.3 1.1 -0.0 0.6 0.2 0.4 -0.0 0.2 0.9 0.0 0.7 -0.2 0.7 -0.9 -0.7 -1.4 -0.7 0.1 1.6 0.8 1.0 1.1 1.0 0.7 1.1 1.1 1.2
Medication: Metformin 1.4 2.0 3.8 1.9 -1.7 -1.5 1.0 -1.9 -1.2 -1.6 -1.4 -1.5 -1.4 -1.4 -1.3 -1.2 -1.2 -1.0 -1.3 -1.4 -1.5 -0.2 1.6 -1.9 -1.5 -0.6 -1.5 -1.6 -1.4 -1.4 -1.4 -1.3 -1.4
Diabetes (father) 5.1 6.4 12.4 -2.3 3.1 2.6 -0.3 2.7 2.8 3.2 2.4 2.6 -0.0 2.3 3.1 2.8 2.0 1.4 2.8 0.0 0.4 -1.6 -2.9 2.4 2.7 1.7 3.5 3.0 2.7 2.6 3.4 3.1 3.3
Diabetes (mother) 1.5 1.9 4.3 -1.1 1.7 2.0 -1.4 1.7 1.3 1.2 2.0 1.3 0.4 2.1 1.9 1.4 1.3 2.0 1.7 0.5 -0.1 0.6 -1.2 1.3 1.5 0.4 1.5 0.8 1.7 1.6 1.5 0.3 0.7
Severe depression (siblings) 0.6 0.6 1.6 -1.1 0.8 1.1 -0.7 0.8 0.3 0.8 1.0 0.9 -1.3 1.0 0.9 0.4 0.5 0.8 0.9 -0.4 -0.8 0.6 -0.8 0.4 0.6 0.3 1.0 0.6 1.2 0.6 0.9 0.2 0.6
Pack years adult smoking proportion 1.0 1.5 4.5 -0.2 1.8 1.9 -1.0 1.0 1.4 1.0 1.8 0.9 0.4 1.9 1.9 1.4 0.1 1.4 2.1 -0.8 -0.6 -0.3 -1.6 0.6 0.5 0.1 1.7 0.8 0.7 0.7 1.6 -0.4 1.0
Impedance of leg (right) 0.4 1.8 5.1 2.0 -1.7 -1.5 1.5 -1.2 -0.3 -2.1 -1.3 -1.8 0.5 -1.3 -1.9 -0.4 -1.4 -0.8 -1.1 -0.1 -0.4 -0.3 1.8 -1.6 -0.2 0.6 -2.3 -1.0 -1.0 -0.1 -2.0 -0.7 -2.0
Leg fat-free mass (left) 0.3 1.7 4.6 -0.9 1.2 1.3 -0.8 1.0 1.0 1.9 1.0 1.8 0.9 1.1 1.6 1.0 1.1 0.7 1.0 0.9 1.0 0.2 -1.8 1.6 0.7 1.5 1.8 1.0 1.0 1.3 1.9 2.1 1.6
Trunk fat percentage 0.7 2.8 5.4 -1.1 2.0 2.0 -0.9 0.6 2.1 2.3 1.8 1.8 0.6 1.9 2.0 2.1 1.6 1.5 2.1 0.9 0.8 0.8 -2.3 2.0 0.9 0.1 2.0 2.0 1.9 2.2 2.0 1.2 1.8
Hand grip strength (right) 0.3 0.8 2.7 1.0 -1.1 -0.6 1.4 -0.5 -0.4 -1.4 -0.5 -0.7 0.6 -0.5 -0.9 -0.4 -0.7 -0.2 -0.7 1.2 1.2 0.9 0.9 -0.4 -0.5 0.5 -1.6 -1.2 -1.1 -0.3 -1.1 -0.6 -1.4
Townsend deprivation index at recruitment 0.5 0.7 3.1 -0.2 0.6 1.1 -1.2 1.4 0.3 0.2 1.2 0.9 1.4 1.2 0.5 0.3 0.0 1.3 0.7 0.9 0.6 1.8 -0.7 0.8 -0.4 -0.1 0.2 -0.1 0.4 0.3 0.3 -0.6 -0.2
Current tobacco smoking 0.1 0.2 0.8 0.7 -0.4 -0.2 -0.2 -0.0 -0.6 -0.4 -0.3 -0.6 -0.3 -0.3 -0.6 -0.5 -0.7 -0.1 -0.3 -0.1 0.0 0.1 0.2 -0.6 0.3 0.9 -0.6 -0.8 -0.2 0.6 -0.5 0.3 -0.5
Average weekly fortified wine intake 2.2 2.6 10.6 0.7 -1.4 -1.4 -0.5 -1.2 -1.3 -1.5 -1.2 -1.5 0.1 -1.3 -1.3 -1.3 -1.9 -1.0 -1.5 1.5 0.9 3.1 1.3 -0.2 -2.2 -3.3 -1.9 -1.1 -1.1 -1.3 -1.7 -3.2 -1.4
Maternal smoking around birth 1.0 1.4 4.1 -1.1 1.9 1.2 -1.2 -0.6 0.3 1.1 0.9 0.1 -0.7 1.0 2.0 0.3 0.6 0.1 1.9 -1.3 -0.1 -1.8 -2.0 0.7 0.9 -0.1 1.5 1.4 0.6 -0.4 2.0 0.5 2.0
Fed-up feelings 0.3 0.6 4.2 2.0 -0.1 0.8 -1.1 -0.0 0.2 -0.8 0.8 -0.5 -1.3 0.8 0.1 0.3 0.5 1.2 0.3 -0.3 -0.7 -0.6 0.3 -0.6 0.0 0.4 -0.5 -0.8 -0.2 -0.3 -0.4 -0.7 -1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.6 2.3 1.4 -0.0 -0.1 -0.4 -1.2 -1.0 -0.7 -0.3 -1.2 -0.9 -0.2 0.1 -0.9 -0.2 -0.4 -0.2 -1.5 -0.9 -1.2 -0.3 -0.9 -0.4 0.6 -0.3 -0.2 -0.6 -1.4 0.0 -0.3 -0.1
Relative age voice broke 0.2 0.3 0.7 -0.6 0.8 0.5 0.3 -0.5 0.2 0.5 0.6 0.3 0.6 0.6 0.6 0.2 0.5 0.3 0.8 -0.2 0.1 -0.4 -0.6 0.5 0.7 0.4 0.8 0.2 0.3 0.1 0.6 0.1 0.7
Taking other prescription medications 2.6 3.9 9.0 -0.6 2.1 1.8 -2.5 1.9 1.9 2.5 1.9 1.6 -0.5 1.8 2.3 1.9 1.1 1.4 2.1 1.1 0.7 0.3 -2.2 2.5 2.1 1.2 2.3 2.4 3.0 2.8 2.5 2.1 2.3
Age when periods started (menarche) 0.4 1.0 3.0 -1.3 1.1 0.9 -0.3 0.9 0.3 0.9 1.0 0.2 1.1 1.0 1.1 0.3 -1.0 0.4 1.1 1.0 1.6 1.7 -1.2 1.3 1.5 1.1 1.3 1.0 0.7 0.4 1.1 -0.1 0.9
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 2.0 -0.9 0.8 1.1 -1.1 1.3 0.4 0.5 1.3 0.6 -0.1 1.2 0.8 0.4 -0.2 1.4 0.8 0.6 0.1 0.6 -0.4 0.8 -0.6 -1.4 0.4 0.2 0.7 0.1 0.4 -1.0 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.4 4.2 -1.2 1.4 1.5 -1.0 0.3 0.3 0.9 1.7 -0.1 -2.1 1.7 1.7 0.3 0.4 1.4 1.7 0.7 0.4 0.0 -1.3 1.4 2.0 1.1 1.3 0.7 1.3 0.6 1.4 0.5 0.6
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 1.7 0.2 -0.3 -0.3 0.5 -1.0 -0.3 -0.4 -0.4 -0.2 0.2 -0.4 -0.2 -0.3 -0.3 -0.2 -0.0 -1.1 -1.1 -0.7 0.2 -0.8 -1.3 -0.7 -0.3 -0.2 -0.7 -0.3 -0.2 -0.6 -0.3
Qualifications: CSEs or equivalent 1.1 1.4 6.8 2.6 -1.6 -0.7 1.2 -0.7 -0.5 -1.6 -0.8 -0.4 -0.1 -0.7 -1.4 -0.5 0.8 0.1 -1.1 0.0 -0.5 1.1 1.8 -1.5 -0.9 -0.3 -1.4 -1.7 -1.2 -0.5 -1.6 -1.3 -2.0
Serious illness, injury or assault to yourself 0.2 0.2 1.6 -0.5 0.3 0.4 -1.2 -0.4 0.3 0.1 0.5 0.4 0.4 0.4 0.6 0.4 0.4 0.5 -0.1 0.8 1.0 0.7 -0.3 0.5 0.5 0.3 0.2 0.2 0.3 -0.5 0.4 -0.1 0.1
High blood pressure 1.0 2.9 6.7 -2.0 2.0 1.7 -1.9 0.4 1.3 1.8 1.7 0.8 -1.9 1.8 1.8 1.3 0.1 1.2 1.9 -0.6 -0.3 -0.9 -1.9 1.0 2.5 2.6 1.4 1.8 1.9 2.4 1.9 2.5 1.5
Hayfever, allergic rhinitis or eczema 0.7 1.5 3.8 1.1 -1.6 -1.9 -0.6 -0.3 -1.1 -1.2 -1.8 -0.6 -0.3 -1.8 -1.7 -1.1 0.3 -1.5 -1.8 0.2 -0.0 1.3 1.3 -0.6 -1.4 -1.9 -1.7 -0.8 -1.0 -1.0 -1.5 -1.2 -0.6
Multivitamins +/- minerals 2.1 2.6 6.1 1.3 -2.1 -2.5 0.4 -1.0 -1.8 -1.9 -2.4 -1.8 -0.1 -2.4 -2.0 -1.8 -1.0 -2.1 -1.9 -0.7 -0.7 -0.6 2.1 -1.8 -1.3 -0.7 -2.4 -1.6 -1.6 -1.2 -1.8 -0.6 -1.2
Stomach or abdominal pain in last month 0.5 0.6 2.8 1.3 -0.4 0.7 0.6 0.7 0.9 0.5 0.6 1.6 -0.2 0.6 -0.2 0.9 1.1 1.3 0.1 0.7 -0.3 0.2 0.7 -0.1 0.1 0.9 0.1 -0.2 1.0 1.7 -0.1 1.3 -0.7
Supplements: Glucosamine 0.2 0.3 2.6 0.2 -0.3 -0.4 -1.0 1.6 -0.2 0.4 -0.3 1.0 1.0 -0.4 -0.3 -0.2 0.4 -0.2 -0.9 0.2 0.0 -0.1 0.5 0.0 -0.4 -1.2 -0.1 0.0 0.4 0.2 -0.1 -0.2 0.2
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 1.1 0.1 -0.5 -0.5 0.3 0.1 -0.5 -0.4 -0.3 -0.6 0.2 -0.4 -0.4 -0.5 -0.9 -0.2 -0.4 0.6 0.9 1.0 0.3 -0.1 -0.2 -0.6 -0.4 -0.2 -0.1 -0.4 -0.5 -1.0 -0.4
Medication: Atenolol 0.2 0.3 1.0 0.3 -0.4 0.3 0.6 -0.7 0.4 -0.6 0.2 0.0 -1.0 0.3 -0.3 0.4 -0.2 0.6 -0.1 -0.2 -1.0 0.3 0.4 -0.5 0.3 0.1 -0.1 -0.8 -0.0 0.8 -0.5 -0.8 -0.9
Medication: Levothyroxine sodium 0.6 1.0 2.0 -0.8 1.2 1.2 -0.8 0.6 0.9 1.2 1.1 0.5 0.8 1.0 1.1 0.9 -0.1 0.6 1.1 0.9 1.4 0.0 -1.0 1.2 1.4 0.8 0.8 1.3 1.4 0.7 1.1 1.4 1.1
Sitting height 0.1 0.7 5.3 1.5 -0.6 -0.1 2.3 0.5 1.0 -0.2 -0.1 1.1 1.9 0.0 -0.3 0.9 0.6 0.4 -0.2 1.3 1.0 0.5 0.1 0.3 -0.7 1.3 0.1 -0.3 -0.4 0.2 -0.2 0.6 -0.7
Chronic bronchitis/emphysema (father) 0.6 0.7 2.4 0.2 0.5 1.3 -1.3 0.4 0.0 0.9 1.3 0.7 -1.2 1.3 0.4 0.1 -0.4 1.5 0.7 -0.3 -0.3 -0.8 -0.4 0.1 0.7 1.2 0.3 0.4 1.2 1.3 0.3 1.6 -0.3
High blood pressure (mother) 1.6 2.3 6.1 -1.1 1.9 1.4 -1.0 0.9 0.8 2.5 1.3 1.6 -0.7 1.3 1.9 0.8 1.1 0.7 1.7 0.3 1.1 -1.0 -2.0 1.6 1.7 0.6 2.0 1.6 1.7 1.3 2.2 2.1 2.4
Body mass index (BMI) 1.5 6.3 12.0 -2.5 3.0 3.1 -2.3 1.7 2.3 3.5 2.9 2.8 0.6 2.9 3.1 2.4 2.7 2.3 2.9 1.0 1.1 0.6 -3.2 2.8 1.7 0.5 3.2 2.6 2.7 2.5 3.2 2.2 2.7
Impedance of leg (left) 0.5 2.4 6.5 2.3 -1.9 -1.5 1.2 -1.6 -0.5 -2.5 -1.3 -2.0 0.2 -1.3 -2.1 -0.5 -1.4 -0.5 -1.2 -0.3 -0.6 -0.1 2.1 -1.9 -0.8 -0.3 -2.6 -1.3 -1.3 -0.6 -2.4 -1.6 -2.5
Leg predicted mass (left) 0.4 1.9 4.9 -0.9 1.3 1.4 -0.7 1.0 1.1 2.0 1.1 1.9 1.1 1.2 1.7 1.1 1.3 0.8 1.1 0.9 1.1 0.3 -1.8 1.7 0.8 1.6 1.9 1.0 1.1 1.4 2.0 2.2 1.6
Trunk fat mass 0.9 3.9 7.2 -1.3 2.3 2.3 -1.3 1.0 2.3 2.7 2.1 2.2 1.2 2.2 2.4 2.3 1.8 1.7 2.3 1.3 1.3 1.0 -2.7 2.4 1.1 0.5 2.4 2.2 2.1 2.4 2.5 1.7 2.1
Waist circumference 1.6 5.9 9.7 -1.8 2.7 2.8 -2.5 1.4 2.6 3.1 2.7 2.6 1.7 2.7 2.8 2.7 2.6 2.2 2.9 1.7 1.9 1.2 -3.1 2.9 1.8 0.8 2.8 2.7 2.5 2.3 2.9 2.2 2.4
Number of incorrect matches in round 1.3 2.1 5.1 -1.1 1.8 0.9 -1.5 1.9 0.7 1.6 1.0 0.9 1.8 1.0 1.8 0.7 0.7 0.3 1.7 1.8 2.2 1.0 -1.7 2.3 0.9 -0.7 1.7 2.0 1.5 0.1 1.9 0.4 2.3
Past tobacco smoking 0.2 0.3 2.1 1.4 -0.2 0.2 1.1 -0.9 0.1 -0.5 0.2 -0.2 0.6 0.2 0.0 0.1 -0.3 0.4 0.2 0.6 0.1 1.0 -0.2 -0.0 -0.7 -0.2 0.0 -0.3 -0.3 -0.1 -0.2 -0.9 -0.6
Alcohol usually taken with meals 0.9 1.5 4.5 0.5 -1.1 -0.8 1.9 -2.1 -0.5 -1.1 -0.5 -0.8 -1.3 -0.6 -1.1 -0.5 -1.1 -0.2 -0.9 -1.2 -1.7 0.0 1.1 -1.4 -1.9 -1.5 -1.2 -1.4 -1.5 -0.8 -1.4 -1.6 -1.5
Nervous feelings 0.2 0.3 2.3 -0.2 -0.4 -0.5 0.6 0.2 -0.5 -0.6 -0.4 -0.6 -1.1 -0.5 -0.3 -0.5 -0.4 -0.4 -0.1 0.2 0.4 1.5 0.2 -0.0 1.0 1.2 -0.5 0.1 0.5 -0.2 -0.3 0.1 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 2.7 1.2 -0.8 -0.3 -0.4 -1.1 -0.8 -1.3 -0.0 -1.3 -1.4 -0.0 -0.7 -0.8 -1.5 0.4 -0.5 0.0 -0.7 0.8 0.8 -0.7 -0.5 0.4 -1.4 -1.0 -0.4 -0.0 -1.0 -0.5 -1.6
Hearing difficulty/problems with background noise 0.7 1.1 4.7 -1.0 1.3 0.7 0.1 0.4 1.2 1.0 0.7 0.7 1.2 0.7 1.3 1.2 2.2 0.3 1.1 0.3 0.9 -0.0 -1.5 1.0 1.3 0.7 1.2 1.2 0.4 -0.3 1.3 1.1 1.4
Hair/balding pattern: Pattern 2 1.1 1.4 3.7 -0.9 1.4 1.5 -1.0 0.6 1.0 0.8 1.4 0.5 1.9 1.5 1.5 1.0 0.7 1.3 1.3 1.5 1.1 1.3 -1.6 1.6 -0.4 -1.5 1.1 0.6 0.6 0.1 1.1 -1.1 0.6
Had menopause 0.2 0.3 1.1 -0.3 0.4 0.8 -0.0 -0.1 0.4 0.2 0.8 0.1 -1.1 0.8 0.1 0.4 -0.2 0.9 0.8 -0.1 -0.5 -0.2 -0.1 0.0 0.3 -0.4 0.2 -0.2 0.5 1.0 -0.1 -0.6 -0.3
Had other major operations 0.4 0.5 4.8 -0.4 0.5 0.6 -2.2 0.7 0.3 0.2 0.7 -0.3 -0.4 0.7 0.6 0.2 -0.9 0.6 0.1 0.8 0.7 1.0 -0.5 0.8 0.2 -0.8 0.3 0.5 0.7 0.5 0.3 -0.7 0.1
Forced vital capacity (FVC) 0.1 0.5 3.2 0.9 -0.9 -0.1 1.8 0.5 0.3 -0.9 -0.1 0.1 0.6 -0.1 -0.7 0.2 -0.1 0.5 -0.8 0.5 -0.2 -0.1 1.0 -0.4 -0.4 1.1 -0.9 -1.0 -0.5 0.3 -0.9 0.1 -1.5
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.4 4.2 -1.5 1.5 1.3 -1.1 0.1 0.1 1.2 1.5 -0.5 -2.0 1.5 1.5 0.0 -0.1 1.0 1.6 0.8 0.6 0.1 -1.5 1.7 1.7 0.9 1.3 0.8 1.3 0.9 1.3 0.8 1.0
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 3.0 0.7 -0.3 -0.8 0.1 -0.3 0.1 -0.3 -0.6 -0.2 -0.5 -0.6 -0.4 0.1 0.2 -0.7 -0.3 -0.9 -0.9 -1.2 -0.0 -0.7 0.3 1.7 -0.6 0.1 -0.2 0.5 -0.2 1.2 0.2
Qualifications: None of the above 0.3 0.7 2.8 -0.7 0.2 1.0 -0.9 1.0 1.0 0.5 1.2 1.3 0.6 1.3 0.1 1.0 0.0 1.7 0.8 0.4 -0.6 0.2 0.2 0.1 0.5 0.4 0.1 0.3 1.2 1.5 -0.1 0.5 -0.7
Financial difficulties in last 2 years 0.2 0.3 2.1 0.2 -0.5 -0.2 -0.1 -1.4 -0.3 -0.5 -0.0 -0.4 0.5 -0.0 -0.1 -0.3 0.4 0.4 -0.3 -0.1 -0.7 1.0 0.5 -0.6 -0.2 -0.8 -0.5 -0.9 -0.2 0.1 -0.3 -0.7 -0.7
Mouth/teeth dental problems 0.6 1.0 3.3 -0.9 0.7 0.8 -0.7 0.0 0.7 1.3 0.7 1.1 -1.0 0.7 0.9 0.7 0.0 0.3 0.4 0.0 0.2 -0.8 -0.7 0.7 1.8 1.5 1.4 1.2 1.4 1.2 1.3 1.8 1.1
Heart attack 0.9 1.2 4.8 -1.1 0.8 0.3 -0.6 -0.1 0.7 1.4 0.1 0.9 -1.9 0.1 0.8 0.7 0.3 -0.4 0.7 -1.8 -1.2 -2.2 -0.8 -0.1 1.0 0.7 1.3 1.6 1.2 0.8 1.3 1.7 1.8
Allergy 0.5 1.1 2.1 -1.4 1.3 1.4 1.2 0.4 1.2 1.2 1.3 0.9 0.8 1.3 1.2 1.1 0.7 1.1 1.2 0.1 0.3 -1.4 -1.0 0.6 0.9 1.1 1.4 0.8 0.6 0.9 1.1 1.1 0.7
Pain all over the body in last month 2.0 2.1 6.5 -1.6 1.9 1.3 -1.8 0.7 1.0 1.4 1.2 0.6 -0.6 1.3 1.6 1.0 0.6 0.6 1.8 0.0 0.5 -1.0 -1.9 1.4 2.5 1.9 1.7 1.6 1.6 1.6 1.9 1.8 1.9
Diabetes (self-reported) 0.8 1.3 5.9 1.6 -0.8 -0.7 -0.1 -2.2 -1.1 -1.0 -0.8 -1.4 -2.4 -0.8 -0.6 -1.1 -0.9 -0.7 -0.8 -1.8 -1.3 -1.2 0.8 -1.6 -0.0 0.8 -1.0 -0.9 -0.6 -0.9 -0.5 0.2 -0.7
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 3.7 0.0 0.0 -0.4 0.3 0.7 -0.3 0.1 -0.4 0.3 0.9 -0.5 0.1 -0.3 1.2 -0.6 -0.3 1.0 1.1 1.9 -0.5 0.8 -0.7 -1.7 0.3 0.4 -0.3 -1.1 0.2 -0.9 0.6
Medication: Ramipril 0.5 0.7 3.8 -0.2 0.6 -0.2 -1.2 0.1 -0.3 0.4 -0.1 -0.7 -0.1 -0.1 0.5 -0.3 -0.5 -0.6 0.1 -0.5 0.0 -1.8 -0.4 0.0 1.8 1.9 -0.1 0.1 0.8 1.0 0.8 2.0 0.9
Medication: Simvastatin 0.7 1.0 2.4 -1.0 1.3 0.9 0.3 0.8 1.5 1.5 1.0 1.1 0.3 0.9 1.0 1.5 1.0 0.6 1.3 -0.6 -0.2 -0.3 -1.4 0.6 0.5 0.4 1.5 1.5 0.7 0.5 1.2 0.8 1.4
Fluid intelligence score 0.8 1.7 4.9 -1.3 1.9 1.0 0.3 0.4 0.7 1.3 0.8 0.5 0.4 0.8 1.6 0.7 0.5 -0.3 1.5 -0.1 1.4 -1.2 -2.1 1.5 2.1 1.6 1.9 1.7 0.8 0.0 1.9 1.3 2.2
Illnesses of siblings 0.2 0.3 2.6 -1.0 -0.1 -0.1 -1.0 0.4 -0.2 -0.1 0.1 0.1 0.1 0.2 0.2 -0.1 -0.3 0.2 -0.2 0.5 -0.2 1.1 0.0 0.2 -1.2 -1.6 -0.1 -0.1 0.0 -0.1 0.0 -1.2 -0.2
Neuroticism score 0.3 0.6 3.0 1.1 -0.6 -0.3 -1.6 -0.7 -0.4 -1.4 -0.4 -1.1 -1.7 -0.4 -0.3 -0.3 0.1 -0.2 -0.6 -0.4 -0.5 0.3 0.4 -0.7 -0.3 0.3 -1.2 -0.6 -0.5 -0.6 -0.5 -0.7 -0.8
Weight 0.6 3.1 6.0 -1.2 1.9 2.1 -1.2 1.1 2.0 2.4 1.9 2.3 1.2 2.0 2.1 2.0 1.9 1.7 1.9 1.1 1.0 0.7 -2.2 2.0 0.8 0.9 2.2 1.7 1.6 2.0 2.2 1.9 1.7
Impedance of arm (right) 0.2 0.9 5.4 1.3 -1.0 -0.9 2.3 -1.2 0.3 -1.3 -0.7 -0.8 0.4 -0.7 -1.2 0.3 -0.1 -0.2 -0.5 -0.1 -1.0 0.2 1.0 -1.0 -0.1 -0.5 -0.9 -0.7 -0.2 0.4 -1.3 -1.4 -1.3
Arm fat percentage (right) 1.4 5.6 10.3 -2.3 2.9 2.8 -1.8 1.3 2.6 3.2 2.6 2.7 0.7 2.7 2.8 2.6 2.9 2.1 2.8 0.8 0.7 0.7 -3.0 2.6 1.5 -0.1 3.0 2.7 2.7 2.6 2.9 1.6 2.6
Trunk fat-free mass 0.4 2.4 5.1 -1.2 1.4 1.6 -1.1 1.9 1.4 2.0 1.4 2.3 2.1 1.4 1.8 1.4 1.4 1.1 1.2 1.4 1.7 0.3 -1.7 1.9 0.8 1.5 1.9 1.2 0.9 1.1 1.9 2.1 1.6
Hip circumference 0.5 2.2 4.3 -1.1 1.6 1.8 -1.1 0.7 2.0 2.1 1.7 1.8 0.5 1.8 1.8 2.0 1.4 1.5 1.6 0.7 0.6 0.6 -1.9 1.6 0.2 -0.1 1.9 1.6 1.3 1.7 1.8 1.1 1.4
Time employed in main current job 0.9 1.0 3.4 1.2 -1.2 -1.3 -0.1 0.1 -1.9 -0.3 -1.1 -0.5 -0.3 -1.2 -1.4 -1.8 -1.6 -1.0 -1.3 -0.1 0.0 -0.3 1.3 -0.8 -1.0 -1.1 -0.8 -1.0 -0.5 -0.8 -1.1 -0.0 -0.5
Alcohol intake versus 10 years previously 0.3 0.4 3.5 0.3 0.3 0.3 0.8 1.1 0.4 0.3 0.2 0.5 1.1 0.2 0.2 0.4 0.6 0.1 0.5 -0.2 -0.3 -0.4 -0.2 0.2 -1.1 -1.9 0.3 -0.1 -0.4 -0.8 0.1 -0.9 0.3
Father’s age at death 1.2 1.6 4.3 1.3 -1.6 -0.9 1.1 -0.5 -0.5 -1.4 -0.7 -0.8 -0.6 -0.7 -1.3 -0.5 -1.4 -0.0 -1.4 -1.1 -2.0 -1.0 2.0 -1.9 -1.4 -0.9 -1.2 -1.9 -1.1 -0.3 -1.5 -1.2 -2.1
Worrier / anxious feelings 0.2 0.3 1.4 0.6 -0.5 -0.3 -0.1 -0.3 -0.1 -1.2 -0.2 -0.6 -0.5 -0.3 -0.2 -0.1 -0.3 -0.2 -0.4 0.7 0.7 0.6 0.4 -0.1 0.1 0.5 -0.7 -1.0 -0.9 -0.6 -0.4 -0.6 -0.7
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 2.2 -0.3 1.3 1.1 -0.7 0.5 1.0 0.8 1.1 0.7 -0.3 1.1 1.5 1.1 1.3 0.8 1.1 -0.7 -0.5 -0.1 -1.5 0.4 0.0 0.0 1.3 1.2 0.7 0.2 1.4 -0.1 0.9
Falls in the last year 0.7 1.0 2.5 -0.4 -0.7 -1.1 -0.2 -1.5 -1.6 -0.7 -1.1 -1.2 -1.2 -1.2 -0.4 -1.6 -1.1 -1.3 -1.6 -1.2 -0.9 -0.9 0.9 -0.9 0.7 1.5 -0.4 0.1 0.0 -0.7 -0.1 0.2 0.1
Hair/balding pattern: Pattern 3 0.6 0.8 4.4 2.1 -1.3 -0.7 0.2 -0.2 -1.0 -0.3 -0.7 0.1 -1.4 -0.7 -1.2 -1.0 0.1 -0.1 -1.2 -0.3 -1.0 0.3 1.3 -0.8 -0.7 0.5 -0.9 -1.3 -0.2 0.4 -1.1 0.6 -1.1
Number of live births 0.5 0.7 2.1 -0.8 0.5 0.2 -1.3 0.4 0.2 1.4 0.1 1.2 -1.2 0.1 0.4 0.2 0.8 -0.1 0.4 -0.0 -0.0 0.0 -0.7 0.8 0.8 0.5 0.8 1.2 1.2 1.1 0.8 1.4 1.3
Forced expiratory volume in 1-second (FEV1) 0.2 0.8 3.8 0.8 -0.9 -0.1 1.5 0.7 0.5 -0.6 -0.1 0.3 -0.1 -0.1 -0.6 0.5 0.4 0.5 -0.8 -0.9 -1.5 -1.7 1.1 -1.1 0.3 2.0 -1.0 -0.8 -0.1 0.9 -0.6 1.2 -1.2
Pulse rate 0.2 0.4 1.5 -0.9 0.2 0.6 0.6 1.2 0.7 0.5 0.6 0.7 0.4 0.7 -0.0 0.7 0.0 0.8 0.9 -0.3 -0.7 -1.2 0.1 -0.0 -1.1 -0.5 0.4 0.1 -0.1 -0.1 -0.0 0.1 -0.1
Happiness 0.3 0.4 2.0 0.5 0.6 0.1 -0.6 -0.1 0.2 -0.1 0.2 -0.3 -1.3 0.2 0.7 0.2 0.5 -0.1 0.5 0.7 0.7 1.0 -0.8 0.8 1.3 1.4 0.3 0.4 0.5 0.7 0.7 0.6 0.5
Noisy workplace 0.3 0.3 1.6 -0.5 -0.3 0.7 -0.1 -0.5 0.4 -0.3 0.7 0.4 0.3 0.8 -0.4 0.5 0.0 1.2 0.2 0.2 -0.0 -0.8 0.5 -0.5 -0.2 1.0 -0.4 -0.5 -0.3 0.2 -0.6 0.4 -1.3
Qualifications: A levels/AS levels or equivalent 0.8 1.7 6.3 -1.1 1.8 0.6 -0.6 -0.3 0.6 1.2 0.6 0.3 1.3 0.6 1.5 0.6 0.7 -0.4 1.2 0.8 2.5 0.3 -2.2 1.6 1.9 2.3 1.4 1.5 0.3 -0.4 1.6 1.6 2.0
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 3.1 -0.1 -0.1 -0.4 -0.0 -0.6 0.2 -0.5 -0.3 -0.6 1.2 -0.3 -0.5 0.2 0.2 -0.4 -0.6 1.8 1.5 0.9 0.1 0.9 -0.1 -0.3 -0.7 -0.2 -0.3 -0.1 -0.5 -0.3 -0.3
Mouth/teeth dental problems: Dentures 0.2 0.4 1.7 0.4 -0.2 0.2 -0.6 0.5 -0.5 -0.7 0.3 -0.4 0.3 0.3 -0.6 -0.4 -0.2 0.8 0.0 0.4 -0.1 0.4 0.6 -0.2 -0.9 -1.2 -0.9 -0.9 -0.4 -0.3 -1.1 -1.3 -1.3
Asthma 0.9 1.8 4.9 0.8 1.0 1.4 -1.6 1.0 1.5 1.0 1.6 1.2 0.2 1.6 1.3 1.5 1.0 1.6 1.3 0.8 0.4 0.6 -1.1 1.2 2.2 2.1 1.5 1.2 1.8 1.8 1.2 1.6 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.6 -0.0 -0.0 0.4 0.4 1.3 0.5 0.6 0.6 0.8 1.0 0.5 -0.3 0.5 1.3 1.0 0.3 1.0 0.3 1.0 0.3 0.3 -0.2 -0.7 0.3 -0.4 0.3 0.9 -0.3 0.1 -0.3
Medication: Cholesterol lowering 3.9 6.0 15.7 -2.7 3.1 2.0 -2.8 2.5 2.2 3.4 1.9 2.3 -0.7 1.8 3.0 2.2 1.6 0.6 2.5 0.2 1.2 -0.8 -3.3 2.6 2.1 0.7 3.4 3.9 2.7 1.5 3.4 2.4 4.0
Depression (self-reported) 0.4 0.5 6.7 0.8 -0.0 -0.3 0.5 -1.3 -0.9 -0.4 -0.3 -1.0 -2.6 -0.4 0.0 -0.9 0.6 -0.4 0.0 0.2 0.4 -0.1 -0.3 0.0 0.6 0.2 -0.1 -0.3 -0.3 -0.3 0.0 0.3 0.1
Medication: Lansoprazole 0.2 0.3 2.6 -1.3 0.4 0.4 -1.6 0.2 0.5 0.3 0.4 0.2 0.2 0.4 0.6 0.5 -0.4 0.2 0.1 -0.0 0.0 -0.0 -0.4 0.5 -0.1 -0.6 0.2 0.7 0.2 0.2 0.6 0.0 0.5
Prospective memory result 0.9 1.1 8.1 1.0 -0.4 0.4 0.2 -0.1 -0.3 -0.6 0.5 -0.3 1.2 0.5 -0.4 -0.2 -0.6 1.1 -0.4 2.6 1.7 2.9 0.4 0.9 -0.4 -1.2 -0.9 -0.6 0.2 0.3 -0.9 -1.3 -1.4
Lung cancer (father) 0.6 0.7 4.0 2.0 -0.9 -0.4 0.1 -0.9 -1.1 -0.8 -0.4 -0.6 -0.9 -0.5 -0.6 -1.1 0.2 0.2 -0.6 -0.3 -0.4 -0.6 1.1 -0.7 -0.9 -1.0 -0.9 -0.6 -0.5 -0.7 -0.7 -0.8 -1.1
Illnesses of mother 4.0 4.9 10.3 2.2 -2.9 -2.6 2.2 -1.3 -1.4 -2.5 -2.6 -1.6 -0.5 -2.6 -3.2 -1.4 -0.9 -1.8 -2.7 -1.2 -2.1 0.7 2.5 -2.5 -3.0 -1.3 -2.7 -2.2 -2.7 -1.6 -3.2 -2.0 -2.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.8 5.7 0.5 -0.3 0.2 1.1 0.5 0.6 0.1 0.1 0.8 -0.4 0.1 -0.0 0.6 0.7 0.4 -0.2 -1.0 -1.5 -1.5 0.4 -0.7 1.0 2.4 0.0 0.1 0.6 1.4 0.2 1.8 -0.2
Pulse wave Arterial Stiffness index 0.2 0.3 1.8 0.5 -0.8 -0.9 0.1 -0.4 -0.0 0.4 -0.7 0.4 -0.1 -0.8 -0.6 -0.1 0.4 -0.3 -1.0 0.4 0.2 0.7 0.3 0.1 -1.3 -0.4 -0.3 0.5 -0.0 0.1 -0.3 0.4 0.1
Impedance of arm (left) 0.6 2.8 7.7 2.2 -2.0 -1.9 2.8 -1.7 -0.7 -2.3 -1.7 -1.6 -0.4 -1.7 -2.2 -0.8 -1.0 -1.1 -1.5 -0.8 -1.7 0.1 1.9 -1.9 -1.3 -1.1 -2.0 -1.6 -1.3 -0.7 -2.3 -2.3 -2.1
Arm fat mass (right) 1.4 5.9 11.0 -2.2 2.8 3.0 -1.7 1.5 2.6 3.3 2.8 2.9 0.9 2.8 2.9 2.6 2.7 2.4 2.8 1.0 0.9 0.6 -3.1 2.6 1.6 0.7 3.0 2.5 2.6 2.8 3.0 2.2 2.4
Trunk predicted mass 0.4 2.4 5.0 -1.2 1.4 1.6 -1.1 1.9 1.4 1.9 1.4 2.2 2.2 1.4 1.7 1.3 1.4 1.1 1.2 1.4 1.8 0.4 -1.7 1.9 0.8 1.4 1.9 1.2 0.9 1.1 1.9 2.0 1.5
Standing height 0.1 1.3 4.9 2.2 -1.6 -1.2 1.7 -0.6 -0.0 -1.3 -1.2 -0.4 1.8 -1.2 -1.2 -0.1 -1.1 -0.7 -1.3 0.6 0.5 0.3 1.1 -0.8 -1.2 1.1 -1.3 -1.2 -1.4 -0.4 -1.1 -0.1 -1.4
Length of working week for main job 0.2 0.2 1.0 -0.5 0.2 0.7 -0.9 1.0 0.1 0.1 0.7 0.5 0.6 0.7 0.1 0.1 -0.5 0.9 0.3 0.6 0.4 0.8 -0.1 0.3 -0.7 -0.0 -0.2 -0.3 0.3 -0.1 -0.0 -0.0 -0.5
Exposure to tobacco smoke at home 0.4 0.5 1.7 0.3 -0.8 -0.5 0.8 0.5 -0.6 -0.5 -0.4 -0.6 -0.6 -0.4 -0.9 -0.6 -1.3 -0.1 -0.4 0.3 0.2 0.9 0.9 -0.5 -0.8 -1.3 -0.9 -0.4 -0.4 -0.1 -1.0 -0.8 -0.9
Breastfed as a baby 1.3 1.6 7.0 1.6 -1.9 -1.0 2.6 0.1 0.0 -1.6 -1.0 -0.4 0.7 -1.0 -1.3 0.0 -0.6 -0.3 -1.4 1.5 0.6 1.4 2.1 -0.7 -1.0 -0.4 -1.4 -1.7 -1.2 -0.1 -1.4 -1.5 -1.9
Tense / ‘highly strung’ 0.7 1.2 4.6 0.3 -1.0 -1.1 0.1 -0.8 -1.2 -1.4 -1.1 -1.6 -2.1 -1.0 -1.1 -1.2 -1.1 -1.0 -0.6 -1.1 -0.9 0.2 1.0 -1.3 -0.8 -0.6 -2.0 -1.0 -1.0 -0.9 -1.1 -0.7 -0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 1.8 2.7 6.5 1.1 -1.5 -1.7 0.1 -2.6 -2.0 -1.9 -1.7 -2.0 -2.0 -1.7 -1.6 -2.0 -1.7 -1.4 -1.8 -1.0 -0.7 0.6 1.1 -1.6 -2.0 -1.0 -1.9 -1.5 -2.0 -1.5 -1.7 -2.1 -1.3
Hair/balding pattern: Pattern 4 0.2 0.5 3.6 -1.1 0.6 0.8 0.4 1.2 0.6 0.3 0.8 0.7 0.8 0.7 0.6 0.6 0.3 0.6 0.7 -0.6 -0.0 -1.9 0.1 -0.1 1.0 0.6 0.7 0.8 0.2 -0.3 0.6 1.0 0.3
Birth weight of first child 1.7 3.1 6.8 2.4 -2.5 -1.6 1.5 -0.4 -0.8 -2.2 -1.6 -1.6 -0.8 -1.5 -2.1 -0.8 -2.1 -0.8 -2.2 -0.3 -0.7 0.0 2.6 -2.0 -2.1 -1.3 -2.2 -2.2 -1.7 -1.3 -2.3 -2.0 -2.5
Peak expiratory flow (PEF) 0.6 1.3 11.3 -0.4 0.1 0.6 0.2 0.7 1.1 0.0 0.6 0.4 -0.7 0.6 0.3 1.0 0.8 1.0 0.1 -0.9 -1.6 -2.0 -0.0 -0.3 1.6 3.4 -0.2 0.0 0.8 2.3 0.4 2.3 -0.4
Pulse wave reflection index 0.4 0.5 1.5 1.1 -1.1 -1.2 -0.0 -0.9 -0.8 -0.2 -1.1 -0.0 -0.6 -1.1 -1.0 -0.8 0.5 -0.6 -1.2 0.3 0.2 1.0 0.6 -0.3 -0.4 -0.2 -0.7 0.0 -0.2 -0.0 -0.7 0.3 -0.3
Ever highly irritable/argumentative for 2 days 0.3 0.3 1.6 -0.1 -0.2 -0.2 -0.2 0.2 -0.0 -0.3 -0.3 0.6 1.2 -0.3 -0.0 -0.0 1.0 -0.2 0.0 1.0 0.7 1.2 0.3 0.2 0.5 1.3 -0.4 0.0 -0.1 0.7 0.1 0.9 -0.0
Loud music exposure frequency 0.4 0.4 4.9 -0.9 0.0 0.1 -2.2 0.3 -0.9 0.4 0.1 -0.2 0.2 0.1 -0.0 -0.9 -0.5 0.0 -0.0 1.0 0.9 1.5 -0.3 0.7 0.0 0.0 -0.1 -0.1 0.2 0.7 0.1 0.4 0.2
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 3.7 -0.4 0.9 -0.4 -0.4 -0.2 -0.5 0.9 -0.4 -0.1 -0.2 -0.5 0.9 -0.5 0.2 -1.3 0.0 -0.3 1.2 0.1 -1.5 0.9 0.3 0.2 1.2 0.7 -0.4 -1.2 1.2 0.4 1.9
Mouth/teeth dental problems: Bleeding gums 0.4 0.6 5.4 0.6 0.1 -0.4 0.3 -0.2 0.2 -0.3 -0.5 -0.3 1.8 -0.4 0.1 0.2 1.1 -0.7 -0.0 1.3 1.3 2.3 -0.6 0.8 -0.2 -0.1 -0.0 0.1 -0.6 -0.2 0.1 -0.4 0.5
Blood clot in the leg (DVT) 0.2 0.2 2.5 0.5 -0.1 0.1 -1.6 -0.2 -0.1 0.4 0.0 -0.2 -0.1 -0.0 -0.1 -0.1 -1.1 -0.0 0.0 0.4 0.4 0.7 -0.2 0.2 -0.2 -0.3 -0.2 -0.5 0.2 0.5 0.0 0.3 0.0
Medication: Paracetamol 3.0 5.0 15.7 -1.6 1.8 2.8 -0.6 2.3 3.2 2.2 3.0 2.8 -0.1 2.9 1.9 3.2 2.1 3.4 2.3 0.5 -1.1 -1.3 -1.0 1.2 2.2 1.0 2.3 1.7 3.4 4.0 1.7 2.1 0.5
Headache pain in last month 0.2 0.3 1.2 0.7 -0.0 0.8 0.4 1.0 0.7 0.5 0.8 0.3 0.1 0.7 0.2 0.7 -1.0 1.1 0.3 0.1 -0.4 0.0 0.1 -0.2 -0.5 0.1 0.3 0.1 0.9 0.8 0.1 0.3 -0.4
Medication for cholesterol, blood pressure or diabetes 2.5 4.1 10.5 2.4 -2.5 -1.5 2.0 -1.7 -1.9 -2.8 -1.4 -1.6 1.0 -1.4 -2.3 -1.9 -0.8 -0.3 -2.2 0.3 -0.8 1.3 2.7 -1.8 -2.2 -1.6 -2.6 -3.2 -2.3 -1.4 -2.8 -2.7 -3.2
Glaucoma (self-reported) 0.3 0.3 1.5 0.9 -0.5 -0.1 -0.3 -0.1 0.4 -0.7 -0.0 0.5 0.4 0.0 -0.3 0.4 0.6 0.3 -0.2 0.2 -0.2 0.8 0.5 -0.4 -0.6 -0.8 -0.2 -0.7 -0.6 -0.8 -0.5 -1.2 -0.9
Gout (self-reported) 1.2 1.7 4.6 -1.2 1.3 0.9 -1.5 0.5 1.4 1.5 0.9 1.0 0.5 0.9 1.4 1.4 1.0 0.6 1.3 0.5 0.9 -0.2 -1.3 1.2 1.7 1.1 1.1 2.1 1.7 1.8 1.6 2.1 1.7
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 2.6 -0.5 1.0 1.1 -0.5 1.6 0.9 1.1 1.1 0.9 0.5 1.0 0.8 0.9 0.3 0.8 0.8 0.9 1.1 -0.2 -0.6 1.0 1.6 1.3 0.9 0.9 1.2 0.9 0.8 1.5 0.7
Medication: Amlodipine 0.3 0.4 1.3 -1.0 0.5 0.6 -0.3 0.4 0.8 0.6 0.7 0.5 -0.9 0.8 0.5 0.8 -0.1 0.8 0.6 0.7 0.8 0.8 -0.3 0.5 0.5 -0.1 0.7 0.9 1.1 0.1 0.4 -0.2 0.1
Medication: Ventolin 100micrograms inhaler 0.6 0.7 2.0 0.2 1.0 1.1 -0.3 0.7 0.5 1.2 1.3 0.8 -0.7 1.3 1.0 0.5 -0.1 1.1 1.4 0.4 1.0 1.2 -1.0 0.9 0.1 -0.6 1.3 0.5 0.6 0.4 0.8 -0.1 0.6
Birth weight 1.2 2.7 6.8 -1.2 1.4 2.3 0.3 1.9 1.2 0.7 2.2 0.4 1.6 2.2 1.6 1.2 -0.4 2.1 2.1 2.6 2.3 2.6 -1.7 2.2 2.0 1.7 1.1 0.5 1.4 1.7 1.2 0.3 -0.1
Chronic bronchitis/emphysema (mother) 1.1 1.2 4.8 0.9 -0.8 -1.4 0.7 -2.2 -1.4 -1.6 -1.6 -1.4 -0.1 -1.6 -0.5 -1.4 -0.3 -1.8 -1.1 -0.8 0.2 -1.1 0.6 -1.0 -0.1 0.9 -1.2 -0.3 -1.2 -1.7 -0.4 -0.5 -0.1
High blood pressure (siblings) 0.3 0.4 3.9 0.8 0.1 0.5 0.3 0.0 0.9 0.1 0.4 0.6 -0.2 0.4 -0.2 0.9 0.7 0.7 0.4 -0.1 -0.0 -0.2 0.2 -0.2 1.4 2.0 -0.1 0.2 0.4 0.7 -0.1 0.9 -0.4
Forced vital capacity (FVC), Best measure 0.1 0.4 4.2 0.8 -0.5 0.0 1.6 0.1 0.6 -0.3 -0.0 0.6 0.4 0.0 -0.2 0.5 0.2 0.4 -0.3 -0.2 -0.6 -0.6 0.5 -0.5 0.3 2.1 -0.1 -0.2 0.1 0.7 -0.2 1.0 -0.7
Body fat percentage 0.8 3.3 6.2 -1.3 2.1 2.2 -1.4 0.8 2.2 2.5 2.0 2.0 0.6 2.1 2.1 2.2 1.7 1.8 2.2 1.0 0.9 0.9 -2.3 2.1 1.0 0.0 2.1 2.1 2.1 2.4 2.1 1.3 1.8
Leg fat percentage (right) 1.1 3.9 7.1 -1.6 2.2 2.5 -2.1 1.0 2.5 2.6 2.4 2.2 0.7 2.5 2.2 2.5 1.6 2.2 2.4 0.7 0.7 0.2 -2.2 1.9 1.3 0.5 2.0 2.3 2.3 2.7 2.2 1.9 1.7
Arm fat-free mass (right) 0.3 1.4 4.0 -0.7 1.2 1.3 -1.4 1.3 0.8 1.6 1.1 1.6 1.3 1.1 1.4 0.8 0.7 0.8 0.8 0.9 1.5 -0.1 -1.5 1.5 0.3 1.6 1.4 0.8 0.5 0.6 1.6 2.0 1.3
Exposure to tobacco smoke outside home 0.5 0.7 2.7 0.2 0.4 1.0 -0.2 0.6 1.5 0.3 0.9 1.1 0.7 1.0 0.5 1.5 0.9 1.2 1.2 -0.1 -0.7 -0.6 -0.1 -0.0 -0.0 0.4 0.2 0.9 0.8 1.7 0.3 0.6 -0.2
Comparative body size at age 10 0.4 1.2 6.0 -1.2 1.2 -0.0 -0.3 -0.6 -0.7 1.2 -0.2 -0.1 -1.2 -0.3 1.3 -0.7 0.2 -1.2 0.6 -0.7 0.8 -0.8 -1.6 0.7 1.6 1.0 1.5 1.0 0.4 -0.1 1.8 1.6 2.5
Number of full brothers 2.2 2.8 5.2 -1.2 2.1 2.2 -2.1 2.1 1.4 2.1 2.2 1.9 1.6 2.2 2.3 1.4 1.6 1.9 2.3 0.2 0.9 -0.2 -2.2 1.4 0.7 0.4 2.1 1.4 1.4 0.7 2.1 0.9 1.5
Worry too long after embarrassment 0.9 1.5 4.1 -0.5 1.3 1.2 -1.8 0.6 1.2 0.5 1.2 0.9 0.3 1.1 1.2 1.2 1.5 0.9 1.2 1.9 1.9 0.7 -1.3 1.8 2.0 1.7 0.8 1.0 1.0 0.9 1.0 1.1 0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.9 -0.3 0.6 0.4 -1.2 -0.1 0.3 0.5 0.5 -0.2 -1.4 0.6 0.5 0.3 -0.1 0.4 0.4 0.2 0.5 0.8 -0.9 0.4 0.9 0.6 0.4 0.7 0.6 0.5 0.5 0.6 0.5
Wheeze or whistling in the chest in last year 0.3 0.5 3.0 0.8 0.2 0.3 -1.7 0.8 -0.2 0.1 0.4 -0.1 -0.4 0.4 0.4 -0.2 -0.6 0.4 0.2 1.1 1.4 1.3 -0.4 0.8 0.7 1.2 0.1 0.2 0.4 0.6 0.4 0.9 0.1
Number of children fathered 0.3 0.3 1.5 0.2 0.4 0.5 0.1 0.4 0.9 0.4 0.5 0.3 -0.1 0.5 0.5 0.9 0.6 0.4 0.6 0.3 0.3 -0.1 -0.3 0.4 1.2 0.7 0.7 0.5 0.5 0.8 0.5 0.4 0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 1.7 -0.4 0.2 0.1 0.4 -1.1 -0.3 -0.1 0.1 0.1 -1.2 0.2 0.3 -0.3 1.3 0.2 0.2 -0.3 0.1 -0.3 -0.6 -0.1 1.2 1.2 0.2 -0.1 -0.1 -0.3 0.3 0.4 0.0
Age at first live birth 2.3 4.0 11.7 2.3 -2.6 -2.4 3.4 -0.5 -0.9 -1.9 -2.3 -1.1 1.5 -2.4 -2.5 -1.0 -2.1 -1.8 -2.2 0.5 0.4 0.7 2.7 -1.6 -2.7 -1.8 -1.8 -1.6 -2.1 -2.2 -2.4 -2.3 -2.0
Pulse wave peak to peak time 0.2 0.3 2.1 -0.2 0.7 0.7 -0.1 0.3 -0.0 -0.6 0.6 -0.6 0.3 0.6 0.6 0.0 -0.5 0.1 0.8 -0.5 -0.2 -0.8 -0.2 -0.2 1.4 0.7 0.2 -0.5 -0.1 -0.1 0.2 -0.4 -0.1
Health satisfaction 2.1 2.7 4.8 -0.7 2.1 1.7 -1.2 1.9 1.5 1.8 1.6 1.3 0.5 1.6 2.1 1.5 1.2 1.0 2.1 1.0 1.3 0.3 -2.0 1.9 1.9 1.8 1.9 2.2 1.6 1.7 2.2 2.0 1.9
Shortness of breath walking on level ground 2.2 2.6 6.1 -2.0 2.2 1.9 -1.4 1.9 1.4 1.5 1.8 1.0 0.2 1.8 2.5 1.4 1.1 1.2 2.2 0.4 0.5 -0.8 -2.1 1.8 1.3 0.2 1.7 1.9 1.7 1.2 2.4 0.9 1.9
Qualifications: College or University degree 0.7 2.2 13.5 -1.2 1.5 0.7 0.2 1.5 1.0 0.8 0.9 0.3 2.2 0.8 1.2 1.0 1.1 0.0 1.1 2.9 3.7 2.5 -2.0 2.8 0.8 -0.8 0.9 0.9 0.1 -0.5 0.9 -0.5 1.4
Eye problems/disorders: None of the above 0.3 0.4 3.7 0.0 0.0 0.3 1.9 -0.8 -0.8 0.0 0.1 -0.3 -0.2 0.1 -0.2 -0.8 -0.8 0.0 0.1 -1.0 -1.0 -0.8 0.1 -0.4 -0.6 -0.5 0.0 -1.0 -0.4 -0.3 -0.3 -0.8 -0.3
Mouth/teeth dental problems: Loose teeth 0.6 0.8 4.1 -1.0 1.0 0.0 -2.0 0.7 -0.2 -0.1 0.0 -0.9 0.8 -0.0 0.7 -0.2 -0.6 -0.9 0.1 0.7 1.7 1.2 -1.0 1.0 0.0 -0.9 -0.0 0.8 -0.7 -1.5 0.5 -0.9 1.0
Emphysema/chronic bronchitis 0.5 0.6 2.2 -0.7 1.1 0.8 0.9 -0.1 -0.4 1.0 1.0 0.6 -0.3 1.1 1.0 -0.3 -0.4 0.6 1.4 0.2 0.8 0.4 -1.0 1.0 0.2 -0.8 1.5 0.4 0.5 -0.1 0.9 -0.4 1.0
Medication for pain relief, constipation, heartburn 1.6 2.8 7.4 0.7 -1.3 -2.0 1.1 -2.6 -2.1 -1.8 -2.2 -2.2 0.2 -2.1 -1.2 -2.2 -1.9 -2.4 -1.7 -1.4 -0.3 -0.6 0.9 -1.5 -1.7 -0.3 -1.4 -1.3 -2.4 -2.7 -1.1 -1.3 -0.5
Neck or shoulder pain in last month 0.3 0.5 4.0 0.1 -0.1 -0.0 -0.4 0.3 0.7 0.7 -0.2 0.7 0.5 -0.1 -0.0 0.6 0.8 -0.1 0.0 0.3 0.4 0.3 -0.3 -0.0 0.6 1.8 0.3 0.8 0.6 1.0 0.4 2.0 0.5
Medication: Blood pressure 0.7 1.3 3.4 -1.4 1.5 0.7 -1.6 0.2 0.4 1.4 0.6 -0.3 -1.5 0.7 1.3 0.4 -1.3 -0.3 1.3 -1.0 0.0 -1.2 -1.6 0.6 1.3 1.3 1.2 1.4 1.0 0.2 1.6 1.2 1.9
Angina (self-reported) 1.3 1.7 4.9 -1.0 1.2 1.5 -0.6 1.8 1.7 1.5 1.5 2.2 0.2 1.5 1.0 1.6 1.3 1.4 1.4 1.0 0.2 0.1 -0.9 1.3 1.2 0.5 1.6 1.0 1.6 2.2 1.1 1.2 0.9
Migraine (self-reported) 0.4 0.5 2.6 -0.2 0.3 1.3 0.1 0.4 0.5 -0.2 1.2 0.2 0.1 1.3 0.4 0.5 0.4 1.6 0.2 0.7 -0.2 0.3 0.3 0.5 0.4 -0.6 -0.1 -0.7 0.8 0.8 -0.2 -1.2 -1.0
Medication: Ibuprofen 0.2 0.2 0.8 0.3 -0.2 0.2 0.8 0.9 0.5 0.5 0.3 0.6 0.8 0.2 -0.4 0.5 0.6 0.7 0.2 0.6 0.3 0.5 0.4 -0.0 0.1 -0.1 0.0 -0.2 0.3 0.9 -0.4 0.5 -0.4
Medication: Allopurinol 1.1 1.4 4.0 -1.6 1.4 0.8 -0.9 0.8 0.9 1.4 0.9 0.9 -0.5 0.9 1.2 0.9 0.4 0.5 1.6 0.2 0.8 -0.3 -1.3 1.1 1.5 1.6 1.1 1.9 1.5 1.2 1.4 2.0 1.7
Medication: Omeprazole 0.9 1.1 4.9 -0.6 1.0 0.9 -0.7 2.2 1.2 1.0 0.7 1.5 -0.9 0.7 1.2 1.2 1.7 0.4 0.9 -0.4 -0.6 -1.0 -0.7 0.8 1.2 0.5 1.1 1.3 1.2 0.8 1.3 1.0 1.2
Medication: Seretide 50 evohaler 3.4 4.0 7.4 -1.3 1.8 2.0 0.4 1.9 2.6 2.1 2.1 2.4 2.7 2.1 1.7 2.6 2.7 2.1 2.0 2.4 2.0 1.7 -1.8 2.3 2.0 0.2 2.5 1.7 2.0 2.0 1.5 0.9 1.2
Mean time to correctly identify matches 0.1 0.2 1.1 -0.2 -0.2 0.1 0.4 -0.3 -0.3 0.1 0.2 -0.4 -0.3 0.2 -0.1 -0.3 -1.0 0.5 0.3 -0.1 0.0 0.6 0.3 -0.2 -0.9 -0.9 -0.2 -0.0 -0.1 -0.7 -0.3 -0.5 -0.4
Heart disease (mother) 2.0 2.5 5.7 -1.7 2.4 2.0 -1.7 1.1 0.5 1.8 1.8 0.9 0.7 1.8 2.0 0.5 0.5 1.0 1.7 0.4 1.4 -1.7 -2.0 1.8 2.2 0.8 2.0 1.5 1.7 0.6 2.0 1.4 1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.8 2.8 -0.7 1.2 0.7 -1.7 1.3 0.3 0.8 0.7 0.4 0.2 0.7 1.1 0.3 0.7 0.2 1.0 0.8 0.8 0.2 -1.5 1.4 0.6 0.4 0.7 0.3 0.8 0.7 1.1 0.5 1.2
Whole body fat mass 1.0 4.1 7.0 -1.4 2.3 2.4 -1.7 1.0 2.3 2.6 2.2 2.2 1.1 2.3 2.3 2.3 2.0 1.9 2.3 1.5 1.4 1.0 -2.6 2.4 1.3 0.6 2.2 2.2 2.2 2.4 2.4 1.8 1.9
Leg fat mass (right) 1.2 4.5 7.9 -1.7 2.4 2.6 -2.4 1.2 2.4 2.8 2.4 2.3 1.0 2.5 2.4 2.4 1.8 2.1 2.5 1.1 1.2 0.4 -2.6 2.3 1.5 1.1 2.2 2.3 2.4 2.6 2.5 2.4 2.0
Arm predicted mass (right) 0.3 1.4 4.7 -0.7 1.1 1.1 -1.3 1.1 0.8 1.6 0.8 1.4 1.3 0.8 1.4 0.7 0.5 0.4 0.8 1.0 1.6 -0.0 -1.6 1.5 0.5 1.8 1.3 0.8 0.5 0.8 1.6 2.2 1.5
Pulse rate, automated reading 0.1 0.3 1.6 -0.7 0.5 0.1 0.4 0.8 0.8 0.4 0.2 -0.4 1.2 0.2 0.4 0.8 -1.1 -0.1 0.9 -0.2 -0.2 -0.5 -0.7 0.2 -0.8 -0.1 0.5 0.5 -0.2 0.6 0.5 0.2 0.6
Alcohol intake frequency. 0.5 1.1 3.9 0.4 1.0 1.2 1.7 0.4 1.2 1.1 1.3 1.7 0.5 1.3 0.9 1.3 1.2 1.3 1.4 -0.6 -1.0 -0.2 -1.0 0.2 -0.7 -1.2 2.0 0.5 0.3 -0.2 0.8 -0.6 0.7
Comparative height size at age 10 0.3 1.5 6.8 2.6 -1.9 -1.4 1.3 -0.5 -0.2 -1.4 -1.3 -0.2 -0.4 -1.4 -1.8 -0.3 -0.8 -0.7 -2.0 0.1 -0.2 0.1 1.7 -1.4 -1.1 0.5 -1.7 -0.9 -0.7 -0.6 -1.8 -0.1 -1.7
Number of full sisters 2.6 3.2 5.8 -1.4 2.0 2.0 -0.7 2.0 2.1 2.1 1.9 2.4 0.4 1.9 2.0 2.1 2.1 1.7 2.4 0.7 0.4 0.5 -1.6 1.5 1.9 1.2 2.4 1.9 2.1 2.2 2.0 1.5 1.7
Suffer from ‘nerves’ 0.8 1.2 3.5 0.7 -1.1 -0.7 1.9 -1.1 -0.6 -1.6 -0.6 -1.1 -1.7 -0.7 -1.3 -0.6 -0.7 -0.2 -0.8 -0.4 -0.7 1.4 1.2 -1.2 -0.7 -0.3 -1.4 -1.1 -0.9 -0.5 -1.5 -1.5 -1.6
Overall health rating 1.0 2.1 4.8 -0.8 2.0 1.7 -1.6 1.5 0.9 1.4 1.7 0.7 -0.9 1.7 1.9 0.9 0.1 1.1 2.2 1.0 1.5 0.7 -2.1 1.9 1.5 0.9 1.5 1.4 1.4 1.4 1.8 1.0 1.5
Chest pain or discomfort 1.9 2.7 6.6 -0.6 1.7 1.8 -2.6 1.3 1.9 1.3 1.7 1.5 -0.4 1.7 1.7 1.9 2.1 1.5 1.7 0.8 0.6 0.9 -2.2 1.8 2.1 1.7 1.3 1.9 2.0 2.0 1.6 1.5 1.2
Had major operations 0.4 0.5 4.1 0.8 -0.3 0.1 0.9 0.5 1.0 -0.4 0.2 0.6 2.0 0.2 -0.5 1.0 1.2 0.6 -0.3 1.0 0.9 0.8 0.3 -0.0 -0.1 0.3 -0.5 -0.2 -0.6 0.3 -0.7 0.1 -0.8
Age at last live birth 1.3 1.9 5.6 1.2 -1.6 -2.2 1.5 -0.4 -1.2 -0.7 -2.3 -0.4 0.7 -2.4 -1.6 -1.2 -1.0 -2.3 -1.8 0.3 1.0 0.7 1.3 -0.6 -1.9 -1.6 -1.0 -0.4 -1.4 -1.6 -1.1 -0.9 -0.1
Family relationship satisfaction 0.5 0.6 3.6 0.8 -0.1 -0.2 -0.1 -0.9 -0.4 -0.7 -0.3 -0.9 -1.9 -0.2 0.1 -0.4 -0.4 -0.4 -0.0 -1.6 -1.4 -0.8 -0.1 -1.0 -0.6 0.0 -0.0 -0.6 -1.1 -0.9 -0.0 -0.9 -0.2
Leg pain on walking 0.5 0.7 3.3 0.9 -1.0 -0.8 0.6 -0.1 -0.1 -0.7 -0.7 0.1 -1.8 -0.7 -1.0 -0.2 0.6 -0.1 -0.6 -0.4 -0.7 -1.6 0.8 -1.0 0.2 1.2 -1.1 -0.6 -0.2 0.8 -0.8 1.1 -0.9
Qualifications: NVQ or HND or HNC or equivalent 2.3 2.8 5.3 2.3 -1.8 -1.4 0.2 -2.2 -1.6 -2.1 -1.5 -2.0 -1.4 -1.4 -1.7 -1.6 -1.3 -0.9 -1.8 -1.6 -2.1 -1.5 1.9 -2.3 -1.2 0.9 -2.2 -2.1 -1.5 -0.7 -1.7 -0.2 -2.0
Commuting to job workplace: Car/motor vehicle 2.5 2.9 5.9 -1.0 1.7 1.9 0.2 1.5 2.4 1.6 1.9 2.0 1.8 1.9 1.8 2.4 1.8 1.8 2.1 1.2 1.4 0.5 -1.3 1.7 1.6 1.0 1.5 2.4 1.9 2.1 1.7 1.3 1.2
Illness, injury, bereavement, stress in last 2 years 0.8 1.0 4.8 -1.4 1.1 0.6 -1.7 2.2 0.3 1.3 0.5 0.7 0.4 0.5 0.9 0.3 0.0 -0.1 0.9 0.6 1.0 0.6 -1.1 1.4 0.8 -0.2 1.0 1.3 1.2 1.0 1.1 0.6 1.5
Medication: Aspirin 1.4 1.9 6.5 -1.2 1.1 1.0 -1.5 1.5 0.8 1.3 0.9 1.0 -0.2 0.8 1.0 0.8 0.5 0.5 0.8 1.8 2.1 2.2 -1.2 1.9 2.6 1.6 0.8 1.5 1.8 1.6 1.1 1.5 1.2
Supplements: Vitamin C 0.2 0.3 1.3 0.2 -0.6 -0.5 0.5 -0.1 0.3 -0.7 -0.6 0.1 1.1 -0.6 -0.7 0.3 -0.1 -0.5 -0.3 0.3 0.5 0.6 0.6 -0.2 -0.3 0.9 -0.8 0.0 -0.6 -0.1 -0.6 0.0 -0.5
Knee pain experienced in last month 0.3 0.4 2.3 0.0 0.3 0.7 -1.5 1.4 0.1 0.5 0.6 0.5 0.9 0.6 0.5 0.1 0.7 0.6 0.5 1.0 0.6 1.0 -0.2 0.7 0.5 -0.5 0.2 0.0 0.7 0.9 0.4 -0.0 0.3
Hypertension (Self-reported) 1.1 2.9 7.0 -2.2 2.0 1.6 -2.3 0.4 1.4 1.8 1.6 0.8 -1.4 1.7 1.9 1.5 0.2 1.0 1.9 -0.6 0.0 -1.1 -2.0 1.0 2.6 2.6 1.5 1.9 1.8 2.1 2.1 2.6 1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.2 1.4 2.8 -0.3 1.3 1.4 -1.4 1.6 1.6 0.9 1.5 1.7 1.3 1.4 1.6 1.6 1.4 1.3 1.1 0.7 0.7 0.1 -1.3 1.2 0.7 0.2 1.5 0.9 0.7 0.5 1.4 0.2 0.8
Illnesses of father: Heart disease 0.8 1.1 6.7 -1.6 0.8 0.9 0.3 2.6 0.8 0.7 0.8 0.5 1.7 0.8 0.6 0.8 -0.1 0.5 0.7 2.1 2.3 1.0 -0.7 1.5 0.9 0.3 0.6 0.2 0.2 0.9 0.5 0.4 0.5
Illnesses of siblings: Diabetes 2.5 3.1 7.7 2.8 -2.1 -1.7 2.5 -1.3 -2.0 -1.7 -1.6 -1.6 -0.8 -1.6 -2.6 -2.1 -2.2 -0.9 -1.6 0.5 0.0 1.3 1.8 -1.2 -1.9 -0.9 -2.1 -2.0 -1.4 -0.9 -2.5 -1.5 -2.2
Smoking status: Previous 0.2 0.3 1.3 -0.8 -0.6 -0.8 -0.0 -0.1 -0.4 -0.1 -0.7 -0.2 -0.3 -0.8 -0.7 -0.5 -0.0 -0.8 -0.9 -0.9 -0.4 -1.2 0.9 -0.7 0.1 0.3 -0.6 -0.3 -0.4 -0.5 -0.5 0.6 -0.0
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.2 1.3 0.7 0.0 -0.2 0.3 -0.7 -0.3 0.2 -0.4 0.1 1.1 -0.4 0.2 -0.3 0.2 -0.6 0.3 -0.4 0.4 -0.5 -0.4 -0.1 -0.2 0.8 -0.0 0.0 -0.5 -0.4 0.3 0.8 0.4
Whole body fat-free mass 0.4 2.1 4.7 -1.1 1.4 1.5 -1.0 1.4 1.3 1.9 1.3 2.1 1.6 1.3 1.8 1.2 1.4 1.0 1.1 1.2 1.5 0.3 -1.8 1.8 0.7 1.6 1.8 1.1 0.9 1.1 1.9 2.2 1.5
Leg fat-free mass (right) 0.2 1.2 2.8 -0.6 1.1 1.2 -0.9 0.7 0.7 1.6 1.0 1.6 0.6 1.0 1.5 0.7 1.0 0.7 0.9 0.6 0.8 0.2 -1.6 1.4 0.3 1.1 1.6 0.7 0.8 0.9 1.7 1.6 1.3
Arm fat percentage (left) 1.1 4.5 8.8 -1.9 2.6 2.5 -1.8 1.1 2.2 3.0 2.2 2.5 0.4 2.3 2.6 2.2 2.5 1.8 2.5 0.6 0.4 0.7 -2.9 2.4 1.2 -0.2 2.7 2.3 2.4 2.4 2.7 1.5 2.5
Average weekly red wine intake 0.6 0.9 5.3 -0.0 -1.0 -0.5 0.8 -0.9 -1.0 -1.2 -0.3 -0.9 -2.3 -0.4 -1.0 -1.0 -1.1 0.2 -0.8 -0.3 -0.6 0.0 1.4 -1.1 -0.1 0.3 -1.4 -0.9 -0.5 -0.3 -1.3 -0.6 -1.7
Handedness (chirality/laterality): Left-handed 0.3 0.4 3.7 -0.1 0.1 0.1 -0.5 0.4 -0.1 0.2 0.2 0.2 1.9 0.2 0.2 -0.2 0.6 0.4 0.3 0.9 0.6 1.0 -0.1 0.4 -0.6 -1.6 -0.3 -0.2 -0.2 0.1 -0.0 -0.5 -0.2
Mood swings 0.5 0.9 2.2 1.5 -0.9 -1.2 -1.1 -1.0 -0.8 -1.1 -1.2 -1.1 -1.4 -1.2 -0.6 -0.8 -0.4 -1.2 -1.0 -1.1 -0.7 -0.9 0.8 -1.3 -0.5 -0.6 -1.0 -0.7 -0.8 -0.9 -0.5 -0.4 -0.3
Loneliness, isolation 0.5 0.8 2.4 0.5 -0.6 -1.0 -0.7 -1.1 -0.9 -1.4 -1.0 -1.5 -1.0 -0.9 -0.6 -0.8 -0.6 -1.0 -0.9 -0.3 0.1 0.9 0.3 -0.8 -0.8 0.3 -1.1 -0.6 -1.2 -1.1 -0.6 -1.2 -0.5
Long-standing illness, disability or infirmity 0.6 1.0 2.8 -0.1 1.4 1.0 -1.5 -0.3 0.8 1.2 0.8 0.1 -0.6 0.8 1.2 0.8 0.5 0.3 1.2 0.0 0.6 0.1 -1.7 1.1 1.4 0.7 0.8 1.6 1.1 0.5 1.3 1.2 1.3
Ever had bowel cancer screening 0.5 0.6 2.7 0.4 0.3 1.0 -0.1 1.2 1.1 0.2 1.2 0.8 -0.7 1.1 0.3 1.1 0.4 1.6 0.8 -0.1 -0.9 -1.0 0.5 -0.1 0.5 0.1 -0.0 0.2 1.2 1.5 -0.0 0.3 -0.7
Diabetes diagnosed by doctor 0.2 0.3 1.7 1.2 -0.2 0.4 0.2 -1.3 0.3 -0.0 0.4 -0.1 -0.9 0.4 -0.1 0.3 0.0 0.8 0.1 -0.8 -0.8 -0.2 0.3 -0.7 0.2 0.6 -0.2 -0.2 0.3 0.3 -0.2 0.3 -0.7
Ever had stillbirth, spontaneous miscarriage or termination 3.7 3.9 8.3 -2.4 2.3 1.7 -2.9 1.5 1.4 2.4 1.8 1.8 0.5 1.7 2.3 1.4 2.2 1.2 2.0 1.0 1.0 0.6 -2.3 2.3 2.8 0.8 2.2 2.3 2.8 2.2 2.4 2.0 2.3
Friendships satisfaction 2.1 2.6 7.5 -1.2 1.9 1.9 -0.5 1.4 1.7 1.0 2.0 1.0 0.7 2.0 1.9 1.7 1.5 1.7 1.6 2.0 1.8 2.7 -1.8 2.2 2.0 1.4 1.9 1.3 1.2 1.5 1.5 -0.2 0.7
Qualifications: nursing, teaching 0.2 0.2 1.6 -0.2 0.1 -0.3 0.6 -1.3 0.1 -0.1 -0.2 -0.4 0.4 -0.2 0.3 0.0 0.0 -0.4 -0.2 0.4 0.8 0.4 -0.5 0.5 -0.9 -0.4 0.1 0.5 -0.4 -0.8 0.3 -0.8 0.3
Commuting to job workplace: Walk 2.3 2.5 4.9 0.5 -1.6 -2.0 0.7 -1.2 -2.1 -1.6 -2.1 -1.8 -0.4 -2.1 -1.6 -2.1 -1.5 -2.1 -2.2 0.4 0.3 1.5 1.4 -0.7 -1.3 -2.0 -1.7 -1.6 -1.7 -1.5 -1.6 -1.8 -0.8
Eye problems/disorders: Cataract 0.4 0.5 1.8 -0.9 0.5 0.1 -1.3 0.7 0.7 0.4 0.0 0.2 -0.1 0.1 0.5 0.7 0.8 -0.2 0.5 0.8 1.1 0.1 -0.7 0.7 0.9 1.2 0.3 1.0 0.2 0.5 0.7 1.2 0.8
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 3.0 1.2 0.0 0.3 1.2 0.7 0.9 -0.4 0.6 0.1 0.8 0.7 0.1 0.9 0.7 1.1 0.7 0.5 -0.3 0.9 0.0 0.1 -0.9 -1.2 0.0 -0.2 0.1 0.2 -0.4 -1.7 -0.8
Medication for cholesterol 0.3 0.5 1.9 0.6 -0.6 -0.7 0.7 0.1 -0.7 -0.6 -0.8 -0.8 0.7 -0.9 -0.4 -0.7 -0.8 -0.9 -0.9 0.7 0.5 0.5 0.5 0.1 -1.3 -1.4 -0.5 -0.6 -0.8 -0.6 -0.5 -1.2 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 3.4 1.8 -0.9 -0.2 1.4 0.0 0.4 -0.6 -0.0 0.2 0.9 0.0 -1.1 0.5 0.7 0.9 -0.5 0.9 0.0 1.4 1.0 -0.5 -0.5 -0.0 -0.8 -0.7 -0.3 0.6 -1.3 -0.3 -1.6
Back pain experienced in last month 0.7 1.1 3.6 -1.2 1.2 1.1 -0.9 1.9 0.8 0.9 0.9 0.7 -1.0 0.9 1.3 0.8 1.5 0.8 0.9 -1.1 -1.3 -0.4 -0.9 0.1 0.8 -0.1 0.9 1.5 1.2 1.2 1.2 0.5 1.0
Mineral and other dietary supplements 0.4 0.6 1.5 -1.1 1.1 0.9 -1.0 -0.7 0.6 0.3 0.8 -0.2 -1.2 0.9 1.1 0.6 -0.0 0.4 1.0 -0.3 0.1 0.2 -1.2 0.6 0.9 0.6 0.8 0.8 0.5 0.3 0.9 0.2 0.7
Breast cancer (self-reported) 0.2 0.2 0.7 0.6 0.3 0.1 -0.2 0.7 0.8 0.2 0.1 0.2 -0.3 0.1 0.4 0.8 0.7 -0.0 0.2 0.2 0.4 0.4 -0.3 0.4 0.7 0.5 0.5 0.4 0.2 0.1 0.5 0.1 0.5
Asthma (self-reported) 0.9 1.8 4.9 0.7 1.1 1.4 -1.7 1.1 1.4 1.1 1.6 1.1 0.3 1.6 1.3 1.4 1.0 1.7 1.4 1.1 0.6 0.9 -1.1 1.4 2.2 2.0 1.4 1.1 1.9 1.8 1.2 1.5 0.4
Osteoporosis (self-reported) 0.6 0.7 2.3 -1.3 1.2 0.7 -0.8 -0.6 -0.3 0.7 0.4 -0.7 -0.7 0.4 1.2 -0.3 -0.8 -0.4 1.1 -0.5 0.2 1.1 -1.3 0.7 0.7 -0.7 0.8 0.9 0.4 0.1 1.3 -0.6 1.5
Osteoarthritis (self-reported) 0.6 0.8 5.6 0.6 -0.3 -0.2 0.7 0.0 0.3 0.1 -0.4 -0.3 -1.6 -0.3 -0.5 0.3 -0.1 -0.2 -0.5 -2.2 -2.4 -2.2 0.5 -1.5 0.4 0.5 0.0 -0.1 0.1 0.6 -0.3 0.8 -0.1
Medication: Aspirin 1.3 1.7 6.6 -1.1 1.0 1.0 -1.5 1.4 0.9 1.2 0.9 1.0 -0.5 0.8 0.9 0.9 0.5 0.6 0.7 1.5 1.6 1.9 -1.0 1.7 2.6 1.9 0.6 1.6 1.9 1.8 1.0 1.5 1.0
Medication: Gliclazide 0.2 0.2 1.2 -0.2 0.3 -0.0 0.0 -1.0 0.1 -0.1 -0.2 0.1 -0.3 -0.1 0.5 0.1 0.2 -0.5 0.1 -0.5 0.6 -0.3 -0.4 -0.1 0.5 0.8 0.4 0.2 -0.6 -1.1 0.5 0.0 0.5
Illnesses of father: None of the above (group 1) 2.9 3.5 8.6 1.8 -1.8 -2.4 0.2 -2.9 -1.7 -1.9 -2.3 -1.4 -0.6 -2.3 -1.9 -1.6 -0.0 -2.0 -1.8 -2.2 -2.6 -1.4 1.8 -2.2 -2.6 -2.0 -2.0 -1.2 -1.7 -2.3 -1.8 -1.6 -1.0
Smoking status: Current 0.1 0.2 0.9 0.6 -0.4 -0.1 -0.2 0.1 -0.5 -0.4 -0.1 -0.6 -0.5 -0.2 -0.5 -0.5 -0.6 0.0 -0.1 -0.2 -0.1 0.0 0.1 -0.5 0.4 1.0 -0.6 -0.7 -0.0 0.7 -0.5 0.4 -0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 1.9 7.2 1.1 -1.6 -1.2 0.8 -1.2 -0.8 -1.1 -1.4 -0.3 -1.6 -1.3 -1.5 -0.8 -0.7 -0.9 -1.7 -2.2 -2.3 -2.7 1.9 -2.2 -1.1 0.6 -1.5 -1.1 -1.1 -0.5 -1.2 0.6 -1.2
Whole body water mass 0.4 2.2 5.0 -1.1 1.4 1.5 -1.1 1.5 1.2 2.0 1.3 2.1 1.6 1.4 1.8 1.2 1.4 1.0 1.2 1.2 1.5 0.2 -1.8 1.8 0.8 1.6 1.9 1.1 1.0 1.2 2.0 2.2 1.6
Leg predicted mass (right) 0.3 1.4 3.2 -0.7 1.2 1.3 -1.0 0.8 0.8 1.8 1.1 1.7 0.7 1.1 1.6 0.8 1.1 0.7 1.0 0.7 0.9 0.2 -1.7 1.5 0.5 1.2 1.8 0.8 0.9 0.9 1.8 1.8 1.5
Arm fat mass (left) 1.4 5.8 11.2 -2.2 2.8 2.9 -2.0 1.5 2.4 3.3 2.6 2.8 0.8 2.7 2.9 2.4 2.6 2.2 2.8 1.0 0.9 0.6 -3.1 2.7 1.6 0.7 3.0 2.5 2.6 2.7 3.0 2.3 2.6
Number of self-reported non-cancer illnesses 1.2 2.0 8.5 -0.9 1.4 0.9 -2.9 0.7 1.1 1.5 0.8 0.5 -1.2 0.8 1.6 1.2 1.0 0.3 1.1 -1.1 -0.8 -2.3 -1.6 0.5 1.7 1.3 1.1 1.4 1.5 1.6 1.9 2.4 1.8
Average weekly champagne plus white wine intake 0.2 0.3 2.2 -0.0 -0.2 -0.6 1.2 -0.1 -0.5 -0.2 -0.4 -0.2 -1.5 -0.4 -0.3 -0.5 -0.7 -0.4 -0.6 -0.8 -0.8 -0.9 0.2 -0.2 -0.4 -0.4 -0.0 0.4 -0.0 -0.1 -0.2 -0.2 0.2
Miserableness 0.1 0.1 0.8 -0.4 0.2 -0.0 -0.0 -0.2 0.1 -0.1 -0.1 -0.5 -0.8 -0.0 0.3 0.1 0.5 -0.2 0.6 0.3 0.4 0.9 -0.5 0.3 0.4 -0.1 -0.1 0.5 0.3 0.2 0.2 -0.4 0.3
Guilty feelings 0.5 0.7 3.0 0.5 -0.1 0.7 -0.6 -0.2 0.1 -0.7 0.9 0.1 0.3 0.9 -0.1 0.1 1.0 1.5 0.3 1.0 0.2 1.6 0.2 0.1 -1.2 -1.4 -0.6 -1.3 -0.5 -0.3 -0.7 -1.7 -1.4
Wears glasses or contact lenses 0.6 0.7 1.9 1.3 -1.1 -0.9 1.2 -0.7 -0.1 -1.0 -0.8 -0.8 0.2 -0.7 -1.2 -0.1 0.2 -0.4 -0.8 -0.2 -0.5 -0.5 1.4 -1.1 -0.5 -0.4 -1.4 -1.1 -0.9 -0.5 -1.2 -0.5 -1.1
Ever taken oral contraceptive pill 1.8 2.0 6.3 1.2 -1.0 -1.3 1.5 -0.6 -1.7 -0.9 -1.4 -1.3 -0.9 -1.4 -1.0 -1.7 -1.2 -1.5 -1.0 -1.5 -1.0 -1.3 1.0 -1.3 -2.2 -2.5 -1.1 -1.4 -1.7 -2.2 -1.0 -1.8 -0.3
Hearing aid user 0.8 0.9 6.1 0.1 -0.6 -0.5 -0.7 -2.5 -1.5 -0.5 -0.4 -1.1 -0.6 -0.4 -0.7 -1.6 -1.8 -0.3 -0.6 -0.5 -0.3 0.1 0.4 -0.6 -1.0 -0.5 -1.0 -1.1 -0.8 -1.0 -0.9 -0.3 -0.8
Mother’s age at death 1.1 1.4 5.2 1.0 -1.4 -1.0 1.7 -0.6 -0.6 -1.3 -0.8 -0.8 1.0 -0.8 -1.6 -0.6 -1.1 -0.3 -1.2 1.1 0.9 2.3 1.5 -0.8 -0.6 0.0 -1.4 -1.2 -1.4 -0.3 -1.7 -1.0 -1.7
Financial situation satisfaction 0.9 1.1 3.7 -0.6 0.9 0.8 -0.3 0.6 0.9 1.3 0.9 1.5 0.2 0.8 1.0 0.9 1.4 0.7 0.8 1.1 0.6 0.6 -1.0 1.2 1.4 1.5 1.4 0.5 0.8 1.4 1.2 1.9 0.9
Tinnitus: Yes, now most or all of the time 1.3 1.6 8.2 -0.9 0.6 1.8 -0.1 1.8 1.3 0.7 2.3 0.9 -1.1 2.2 0.6 1.2 -0.3 2.9 1.3 1.5 0.1 0.7 -0.1 1.0 1.0 -0.5 0.9 0.2 1.9 1.6 -0.0 -0.5 -1.1
Commuting to job workplace: Public transport 0.4 0.4 3.4 0.2 -0.7 -0.3 1.1 -0.1 -0.3 -0.3 -0.2 -0.2 -0.5 -0.2 -0.6 -0.3 -0.7 0.0 -0.7 0.0 -0.4 0.3 0.4 -0.3 -1.8 -1.3 -0.2 -1.1 -0.8 -0.7 -0.6 -0.8 -0.7
Eye problems/disorders: Glaucoma 0.6 0.7 3.4 0.4 0.2 0.7 -0.0 1.3 1.6 0.1 0.8 1.5 1.8 0.9 0.3 1.6 1.3 1.2 0.7 0.9 0.5 1.0 0.1 0.3 0.2 -0.1 0.5 0.5 0.5 0.1 0.1 -0.3 -0.5
Medication: Blood pressure 0.3 0.6 2.6 -0.9 0.2 0.7 -0.4 -0.2 0.6 0.5 0.8 1.0 -1.2 0.9 -0.0 0.7 1.3 1.3 0.5 -0.2 -0.4 -0.3 -0.0 -0.2 1.3 1.6 0.1 0.1 0.8 1.1 -0.0 1.6 -0.5
Pain type(s) experienced in last month: Hip pain 0.8 1.0 4.0 0.8 -0.5 -0.6 -1.3 -0.6 -1.1 -0.4 -0.8 -0.6 -1.9 -0.7 -0.3 -1.1 -0.5 -0.8 -0.7 -1.9 -1.9 -1.5 0.3 -1.3 0.2 2.0 -0.5 -0.4 -0.6 0.8 0.1 1.4 0.1
Supplements: Fish oil (including cod liver oil) 0.3 0.4 5.3 0.9 -0.2 -0.4 0.4 -0.1 0.1 0.1 -0.4 0.2 2.3 -0.5 -0.2 0.1 0.8 -0.3 -0.4 0.8 0.7 0.3 0.2 0.4 0.3 0.4 -0.2 0.1 0.0 0.4 0.0 0.7 0.2
High cholesterol (Self-reported) 2.3 4.0 7.7 -1.8 2.5 2.1 -2.6 2.0 1.7 2.8 2.2 1.9 -0.9 2.2 2.5 1.7 1.3 1.5 2.4 0.1 0.3 -0.8 -2.6 2.0 1.6 0.6 2.5 2.5 2.3 1.6 2.7 2.0 2.5
Medication: Bendroflumethiazide 1.0 1.5 6.7 -1.7 0.6 1.4 -0.1 0.8 1.1 0.7 1.6 0.8 0.1 1.7 0.6 1.1 0.1 2.0 1.1 0.8 0.3 0.4 -0.4 0.7 2.1 2.6 0.7 0.3 1.5 2.3 0.5 1.4 -0.5
Medication: Paracetamol 1.6 2.5 12.0 -0.6 0.6 1.9 0.1 1.5 2.5 1.1 2.2 1.8 -0.3 2.1 0.6 2.5 1.1 3.0 1.3 0.6 -1.1 -0.6 0.2 0.2 1.7 1.3 0.7 0.8 2.6 3.5 0.4 1.6 -0.8
Medication: Lisinopril 3.3 4.3 8.3 -2.5 2.6 2.5 -2.0 2.0 1.6 2.7 2.6 2.0 -0.5 2.7 2.6 1.7 1.3 2.3 2.9 -0.4 -0.1 -1.1 -2.4 1.6 1.5 1.0 2.6 2.4 2.5 1.5 2.6 2.1 2.0
Medication: Atorvastatin 2.2 2.7 10.4 -0.8 1.8 1.6 -3.2 1.3 0.9 2.2 1.5 1.8 -0.7 1.5 2.0 0.9 1.4 1.0 1.6 1.1 2.0 0.2 -2.2 2.0 1.5 0.6 1.9 1.8 1.6 0.9 2.1 2.0 2.1
Illnesses of father: High blood pressure 4.5 5.6 14.2 -1.9 2.7 2.4 -2.4 2.0 1.9 2.4 2.3 1.8 2.1 2.2 2.7 1.9 2.1 1.5 2.2 2.9 3.8 3.0 -3.2 3.5 2.5 0.6 2.6 2.4 1.9 0.9 2.6 0.9 2.4
Alcohol drinker status: Never 0.4 0.4 3.3 0.0 -0.5 0.3 1.8 0.1 0.1 -0.0 0.4 0.2 -1.2 0.4 -0.4 0.1 -0.8 1.0 -0.2 0.1 -0.7 0.5 0.4 -0.5 -1.2 -1.0 0.4 -0.4 0.1 -0.2 -0.5 -1.0 -1.0
Ever smoked 0.3 0.4 1.2 -0.4 -0.6 -0.9 -0.8 0.4 -0.9 -0.6 -0.8 -0.7 -0.7 -0.9 -0.9 -0.9 -0.4 -0.9 -0.9 -0.2 0.1 -0.1 0.9 -0.4 0.3 -0.4 -1.1 -0.5 -0.3 -0.1 -0.8 0.0 -0.3
Basal metabolic rate 0.4 2.3 4.6 -1.1 1.5 1.7 -1.2 1.3 1.4 2.1 1.4 2.1 1.4 1.5 1.9 1.4 1.6 1.1 1.3 1.1 1.3 0.4 -1.9 1.9 0.7 1.5 1.9 1.2 1.1 1.4 2.0 2.1 1.6
Leg fat percentage (left) 0.9 3.2 6.1 -1.4 2.1 2.5 -2.1 0.8 2.3 2.3 2.4 2.0 0.4 2.4 2.0 2.3 1.6 2.3 2.3 0.6 0.4 0.3 -2.0 1.6 0.9 -0.1 1.8 2.0 2.0 2.3 1.9 1.3 1.3
Arm fat-free mass (left) 0.5 2.4 5.7 -1.3 1.5 1.7 -1.3 1.3 1.3 2.1 1.5 1.9 1.7 1.5 1.8 1.3 1.1 1.2 1.3 1.3 1.8 0.1 -1.8 1.8 1.0 1.8 1.7 1.3 1.1 1.2 1.9 2.4 1.5
Number of operations (self-reported) 0.1 0.1 0.5 -0.0 0.3 0.5 -0.7 0.2 0.3 0.2 0.5 0.2 0.0 0.5 0.2 0.3 0.1 0.5 0.2 0.0 0.1 0.3 -0.3 0.0 -0.1 0.0 0.2 0.1 -0.2 0.2 0.1 -0.2 -0.0
Average weekly beer plus cider intake 1.6 2.3 6.5 -1.8 2.2 1.2 -1.3 1.3 0.5 1.6 0.9 0.7 2.5 0.9 2.2 0.5 0.5 -0.1 1.8 0.7 1.7 0.3 -2.1 1.9 0.3 -1.6 2.2 2.1 1.2 -0.5 2.2 -0.7 2.6
Irritability 0.5 0.9 4.4 -0.4 0.7 0.9 -2.1 1.0 0.6 0.7 1.0 1.2 -0.4 0.9 1.2 0.6 1.4 1.0 0.8 0.7 0.7 0.9 -0.7 0.7 0.9 0.5 0.8 0.9 1.0 0.8 1.1 0.7 0.5
Risk taking 1.3 2.0 23.7 -1.2 1.7 0.9 -4.9 1.3 -0.7 1.4 0.9 -0.0 -0.2 0.8 1.6 -0.7 -1.0 -0.0 1.0 -0.1 1.0 -1.0 -1.6 1.4 0.5 -0.7 0.9 1.4 1.0 0.3 1.6 0.8 2.1
Ever had prostate specific antigen (PSA) test 1.0 1.2 3.2 1.1 -1.2 -1.6 -0.4 -1.1 -0.4 -1.0 -1.5 -0.6 -0.1 -1.4 -1.3 -0.4 0.6 -1.2 -1.5 -0.9 -0.8 -1.4 1.0 -1.3 -1.3 -0.6 -1.3 -0.6 -1.3 -1.8 -1.2 -0.7 -0.7
Fractured/broken bones in last 5 years 3.7 4.8 9.0 0.9 -2.0 -2.6 0.4 -2.6 -3.0 -2.0 -2.7 -2.2 -0.7 -2.7 -1.5 -3.0 -2.6 -2.9 -2.7 -2.4 -1.9 -1.4 2.1 -2.6 -2.7 -1.5 -1.7 -2.0 -2.5 -2.8 -1.2 -2.1 -0.7
Age started oral contraceptive pill 1.0 1.2 4.8 1.2 -1.3 -0.2 2.1 -0.4 0.3 -1.3 -0.1 -0.3 0.2 -0.2 -1.3 0.3 -1.0 0.6 -0.9 0.7 0.0 1.0 1.7 -0.9 -1.0 -1.1 -1.1 -1.3 -1.0 -0.2 -1.8 -2.0 -2.2
Diastolic blood pressure, automated reading 0.3 1.0 3.5 -0.8 0.6 1.1 0.2 1.2 1.4 1.1 1.0 1.7 1.9 1.0 0.6 1.4 0.6 1.2 1.2 0.2 -0.4 0.0 -0.4 0.5 -0.1 0.8 0.6 0.6 0.8 1.9 0.7 1.1 0.2
Ever depressed for a whole week 0.9 1.1 5.7 -0.0 -1.1 -1.5 0.5 -0.3 -1.2 -0.8 -1.5 -0.9 -2.4 -1.4 -1.2 -1.2 -1.0 -1.4 -1.0 -1.1 -1.0 -0.7 0.7 -1.1 -0.3 1.2 -1.4 -0.5 -0.7 -0.1 -0.9 0.6 -0.3
Unable to work because of sickness or disability 0.5 0.7 3.5 -1.2 0.7 1.0 -0.7 1.2 0.5 0.6 1.1 0.3 -0.4 1.1 1.0 0.6 -0.2 1.0 1.1 -0.4 -0.3 0.6 -0.9 0.2 -1.0 -1.9 0.7 0.6 0.1 -0.5 0.7 -1.2 0.3
Commuting to job workplace: Cycle 1.2 1.5 12.7 -0.1 0.8 0.2 -1.2 0.1 -0.4 1.0 0.0 0.1 -1.4 0.0 0.9 -0.5 0.2 -0.6 -0.0 -2.7 -2.0 -3.6 -0.7 -0.6 0.7 1.5 0.8 0.9 0.8 -0.2 1.3 1.9 1.5
Myopia 1.4 2.0 8.6 1.4 -0.9 -1.1 -0.2 -2.0 -1.3 -1.1 -1.1 -1.2 -0.1 -1.1 -0.8 -1.3 -1.3 -1.1 -1.1 -2.1 -1.8 -1.8 0.7 -1.7 -2.9 -1.3 -0.8 -1.4 -2.1 -2.3 -0.9 -1.3 -0.6
Vascular/heart problems diagnosed by doctor 1.1 3.0 6.5 1.8 -1.9 -1.6 1.5 -0.5 -1.4 -2.0 -1.6 -1.2 2.0 -1.7 -1.8 -1.5 -0.4 -1.2 -1.9 0.7 0.4 1.1 1.8 -1.0 -2.5 -2.5 -1.6 -2.0 -2.1 -2.5 -2.0 -2.5 -1.6
Cholesterol lowering medication 0.4 0.6 2.0 -0.4 0.4 1.0 -0.2 0.6 0.7 0.7 1.1 1.0 -1.0 1.1 0.3 0.6 0.7 1.4 0.9 -0.2 -0.4 0.4 -0.4 0.3 1.2 1.3 0.6 0.1 0.7 1.0 0.2 0.9 -0.4
Medication: Omeprazole (e.g. Zanprol) 0.7 0.9 5.1 -0.3 0.6 1.0 -0.5 2.3 1.0 0.7 0.9 1.5 -1.0 0.9 0.9 1.0 1.5 1.0 0.8 -0.1 -0.8 -0.6 -0.3 0.5 0.9 0.4 0.9 0.8 1.2 0.7 1.0 0.7 0.5
Pain experienced in last month 0.2 0.4 1.8 -0.4 0.4 0.2 0.7 -0.3 0.6 0.5 0.3 0.7 1.3 0.3 0.3 0.5 0.5 0.0 0.1 1.1 1.4 0.8 -0.7 1.1 0.1 -0.5 0.7 0.7 0.1 -0.5 0.2 -0.2 0.5
Supplements: Calcium 0.4 0.4 1.6 -1.2 0.7 0.1 -0.2 0.7 0.4 0.2 0.2 0.4 0.3 0.1 0.6 0.4 0.6 -0.3 0.8 -0.4 -0.1 -0.4 -0.4 0.3 1.2 1.3 1.0 0.9 0.5 -0.3 0.7 0.3 0.9
Basal cell carcinoma (self-reported) 2.2 2.6 4.9 0.6 -2.2 -2.1 2.0 -0.6 -1.9 -1.6 -2.2 -1.3 -0.7 -2.2 -2.1 -1.9 -1.9 -1.9 -2.2 -0.6 -0.3 0.1 2.0 -1.6 -1.8 -0.8 -1.5 -1.4 -1.7 -1.8 -1.8 -1.1 -1.2
Heart attack/myocardial infarction (self-reported) 0.9 1.2 4.9 -1.2 0.8 0.2 -0.7 -0.1 0.7 1.4 0.1 0.8 -1.7 0.0 0.7 0.7 0.2 -0.5 0.7 -1.8 -1.2 -2.2 -0.8 -0.2 1.0 0.6 1.3 1.5 1.1 0.8 1.3 1.7 1.8
Deep venous thrombosis (DVT) (self-reported) 0.2 0.2 2.9 0.5 -0.2 -0.1 -1.7 -0.3 -0.2 0.3 -0.1 -0.3 0.0 -0.2 -0.2 -0.2 -1.1 -0.2 -0.1 0.4 0.4 0.5 -0.1 0.1 -0.0 -0.2 -0.3 -0.5 0.2 0.7 -0.1 0.6 0.0
Heart disease (siblings) 0.4 0.5 1.6 -0.6 0.8 0.4 0.8 0.5 0.4 0.3 0.1 -0.3 0.5 0.1 0.9 0.5 0.6 -0.4 0.5 0.3 1.1 -0.4 -1.0 0.5 1.3 1.2 0.6 0.6 -0.1 0.2 1.0 1.2 1.1
Alcohol drinker status: Previous 0.8 0.9 2.1 0.0 1.2 0.9 1.0 0.2 0.9 1.3 0.9 0.7 0.4 1.0 0.8 0.9 0.6 0.8 1.3 0.5 0.7 0.0 -1.5 1.1 1.1 0.6 1.4 1.3 1.1 0.9 0.9 0.9 1.0
Pack years of smoking 1.1 1.6 4.4 -0.4 1.8 1.9 -1.2 1.1 1.4 1.2 1.8 1.0 0.4 1.9 2.0 1.4 -0.0 1.3 2.1 -0.8 -0.6 -0.3 -1.6 0.7 0.4 0.2 1.7 1.0 0.8 0.7 1.8 -0.1 1.2
Impedance of whole body 0.5 2.8 6.1 2.3 -2.0 -1.8 2.4 -1.9 -0.6 -2.5 -1.6 -1.9 0.1 -1.6 -2.2 -0.6 -1.3 -0.9 -1.3 -0.6 -1.2 -0.1 2.0 -2.0 -1.2 -0.6 -2.3 -1.5 -1.5 -0.7 -2.4 -2.0 -2.4
Leg fat mass (left) 1.1 4.3 7.4 -1.7 2.4 2.6 -2.5 1.2 2.3 2.7 2.4 2.2 0.7 2.5 2.4 2.3 1.9 2.1 2.4 1.0 1.0 0.5 -2.5 2.3 1.4 0.8 2.1 2.2 2.3 2.4 2.4 2.1 1.9
Arm predicted mass (left) 0.4 2.2 4.8 -1.1 1.4 1.7 -1.4 1.3 1.3 2.0 1.5 1.9 1.7 1.5 1.7 1.3 1.0 1.2 1.2 1.3 1.7 0.2 -1.7 1.7 0.8 1.6 1.6 1.2 1.0 1.1 1.8 2.2 1.4