[Hub]/) : Traits : BMI : ← →

chr2:46,021,381-47,829,230

Best TWAS P=4.67e-13 · Best GWAS P=6.36e-16 conditioned to 0.000201

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CRIPT	0.23	0.23	lasso	5	0.24	6.2e-29	-6.4	-5.9	3.0e-09	0.31	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CRIPT	0.12	0.10	lasso	3	0.09	7.1e-08	-6.4	-7.1	9.7e-13	0.41	0.95	0.04	FALSE
3	GTEx	Adrenal Gland	CRIPT	0.16	0.10	enet	11	0.13	2.3e-05	-6.1	-6.4	1.9e-10	0.34	0.68	0.03	FALSE
4	GTEx	Artery Aorta	CRIPT	0.16	0.06	lasso	6	0.06	3.8e-04	-6.5	-6.4	1.7e-10	0.36	0.84	0.04	FALSE
5	GTEx	Artery Tibial	CRIPT	0.22	0.17	lasso	5	0.22	7.5e-17	-5.2	-5.9	2.9e-09	0.34	1.00	0.00	FALSE
6	GTEx	Brain Cortex	CRIPT	0.35	0.17	lasso	7	0.09	2.1e-03	-5.2	-5.2	2.1e-07	0.35	0.25	0.11	FALSE
7	GTEx	Brain Nucleus accumbens basal ganglia	CRIPT	0.27	-0.01	enet	8	0.02	1.2e-01	-6.5	-5.1	2.7e-07	0.36	0.12	0.10	FALSE
8	GTEx	Breast Mammary Tissue (Female)	AC016722.4	0.20	0.05	lasso	3	0.05	1.3e-02	3.9	5.8	8.8e-09	-0.38	0.06	0.34	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	CRIPT	0.28	0.16	enet	10	0.23	5.4e-08	-5.2	-6.8	8.4e-12	0.41	0.77	0.10	FALSE
10	GTEx	Colon Sigmoid	ATP6V1E2	0.25	0.08	enet	17	0.13	3.3e-05	-4.8	5.3	1.3e-07	-0.34	0.54	0.21	FALSE
11	GTEx	Esophagus Gastroesophageal Junction	CRIPT	0.21	0.14	enet	9	0.18	6.4e-07	-4.0	-5.8	8.1e-09	0.35	0.77	0.02	FALSE
12	GTEx	Esophagus Mucosa	ATP6V1E2	0.26	0.17	lasso	9	0.18	5.4e-12	-3.4	5.6	2.3e-08	-0.39	1.00	0.00	FALSE
13	GTEx	Esophagus Muscularis	CRIPT	0.15	0.21	lasso	4	0.20	2.1e-12	-6.4	-6.4	1.5e-10	0.29	1.00	0.00	FALSE
14	GTEx	Muscle Skeletal	CRIPT	0.14	0.05	enet	25	0.08	1.8e-08	-5.2	-7.0	2.0e-12	0.36	0.99	0.00	FALSE
15	GTEx	Muscle Skeletal	ATP6V1E2	0.30	0.16	enet	27	0.21	2.5e-20	3.1	5.7	1.0e-08	-0.37	1.00	0.00	FALSE
16	GTEx	Nerve Tibial	CRIPT	0.17	0.16	enet	9	0.20	2.3e-14	-4.0	-5.9	4.4e-09	0.32	1.00	0.00	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	CRIPT	0.16	0.19	enet	8	0.21	9.7e-12	-6.3	-6.2	5.5e-10	0.31	1.00	0.00	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	PIGF	0.14	0.08	lasso	4	0.07	1.7e-04	-7.2	7.2	4.7e-13	-0.83	0.01	0.98	TRUE
19	GTEx	Skin Sun Exposed Lower leg	CRIPT	0.19	0.09	lasso	6	0.10	8.6e-09	-6.4	-5.8	9.0e-09	0.32	1.00	0.00	FALSE
20	GTEx	Skin Sun Exposed Lower leg	ATP6V1E2	0.36	0.17	lasso	10	0.28	2.8e-23	-3.5	5.7	9.7e-09	-0.46	1.00	0.00	FALSE
21	GTEx	Stomach	CRIPT	0.14	0.14	lasso	2	0.16	5.0e-08	-4.0	-5.3	1.2e-07	0.28	0.92	0.01	FALSE
22	GTEx	Testis	CRIPT	0.32	0.25	lasso	5	0.24	7.3e-11	-6.4	-5.7	9.7e-09	0.30	1.00	0.00	FALSE
23	GTEx	Testis	SOCS5	0.17	0.01	lasso	3	0.03	1.2e-02	4.8	6.6	3.4e-11	-0.36	0.09	0.55	FALSE
24	GTEx	Thyroid	CRIPT	0.08	0.10	lasso	2	0.11	5.1e-09	-6.4	-6.3	3.7e-10	0.31	0.98	0.01	FALSE
25	GTEx	Vagina	ATP6V1E2	0.31	0.00	lasso	7	-0.01	6.5e-01	-3.5	6.1	1.3e-09	-0.36	0.08	0.18	FALSE
26	GTEx	Whole Blood	CRIPT	0.11	0.04	enet	18	0.05	1.2e-05	-6.3	-5.8	5.7e-09	0.33	0.84	0.08	FALSE
27	METSIM	Adipose	CRIPT	0.07	0.08	bslmm	667	0.07	2.0e-10	-5.2	-5.5	3.2e-08	0.36	1.00	0.00	FALSE
28	NTR	Blood	CRIPT	0.04	0.05	lasso	6	0.05	3.0e-15	-6.3	6.7	2.4e-11	-0.34	1.00	0.00	FALSE
29	ROSMAP	Brain Pre-frontal Cortex	CRIPT	0.36	0.31	enet	24	0.32	1.3e-41	-6.3	-6.7	1.8e-11	0.33	1.00	0.00	FALSE
30	YFS	Blood	CRIPT	0.42	0.51	lasso	5	0.52	1.1e-203	-6.3	-6.3	3.5e-10	0.31	1.00	0.00	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	ATP6V1E2	0.13	0.03	blup	76	0.04	3.8e-09	-4.8	6.8	7.7e-12	-0.36	0.19	0.79	FALSE
32	The Cancer Genome Atlas	Colon Adenocarcinoma	CRIPT	0.10	0.06	blup	66	0.07	5.6e-05	-5.0	-6.6	5.2e-11	0.33	0.46	0.25	FALSE
33	The Cancer Genome Atlas	Esophageal Carcinoma	CRIPT	0.20	0.10	enet	10	0.16	1.3e-05	-5.2	-5.5	4.3e-08	0.34	0.18	0.40	FALSE
34	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CRIPT	0.13	0.12	lasso	5	0.11	5.5e-12	-6.4	-6.4	2.0e-10	0.31	0.22	0.78	FALSE
35	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CRIPT	0.11	0.11	lasso	3	0.10	1.7e-06	-6.1	-6.7	2.3e-11	0.34	0.26	0.73	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	CRIPT	0.18	0.14	lasso	3	0.17	2.1e-18	-6.4	-6.2	6.4e-10	0.33	0.32	0.68	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	CRIPT	0.07	0.08	lasso	2	0.08	3.6e-09	-6.3	-6.0	1.6e-09	0.28	0.23	0.77	FALSE
38	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CRIPT	0.13	0.07	enet	13	0.10	7.9e-05	-6.3	-6.1	9.8e-10	0.35	0.09	0.40	FALSE
39	The Cancer Genome Atlas	Prostate Adenocarcinoma	CRIPT	0.13	0.13	lasso	3	0.15	1.2e-15	-6.5	-6.8	1.3e-11	0.37	0.16	0.84	FALSE
40	The Cancer Genome Atlas	Rectum Adenocarcinoma	CRIPT	0.25	0.10	enet	7	0.15	1.9e-04	-5.2	-6.0	1.9e-09	0.33	0.06	0.15	FALSE
41	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PIGF	0.18	0.10	enet	7	0.08	9.3e-04	-4.0	-5.9	4.1e-09	0.34	0.10	0.32	FALSE
42	The Cancer Genome Atlas	Thyroid Carcinoma	CRIPT	0.11	0.10	lasso	4	0.11	1.6e-10	-5.2	-6.2	5.0e-10	0.32	0.57	0.42	FALSE