TWAS hub - PIGF

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1785	0.0525	4.7e-05	0.099	NA	0.100	NA	0.098	3.7e-08	NA	2.9e-08	NA	4.5e-08
2	GTEx	Nerve Tibial	0.2946	0.0573	7.6e-08	0.102	NA	0.067	NA	0.098	1.0e-07	NA	1.7e-05	NA	2.0e-07
3	GTEx	Skin Not Sun Exposed Suprapubic	0.1380	0.0490	1.1e-03	0.077	NA	0.056	NA	0.066	5.0e-05	NA	5.2e-04	NA	1.7e-04
4	ROSMAP	Brain Pre-frontal Cortex	0.0752	0.0235	2.8e-04	0.031	0.043	0.063	0.058	0.067	6.0e-05	3.1e-06	1.6e-08	5.8e-08	5.8e-09
5	TCGA	Breast Invasive Carcinoma	0.0538	0.0220	1.2e-07	0.041	0.038	0.045	NA	0.049	6.1e-09	2.6e-08	1.4e-09	NA	2.1e-10
6	TCGA	Esophageal Carcinoma	0.2010	0.0790	5.2e-04	0.042	0.103	0.092	NA	0.103	1.8e-02	3.7e-04	7.3e-04	NA	3.8e-04
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.1028	0.0489	5.5e-07	0.064	0.055	0.060	NA	0.072	9.4e-08	7.5e-07	2.6e-07	NA	1.7e-08
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0802	0.0266	2.0e-08	0.056	0.065	0.062	NA	0.059	6.5e-07	7.3e-08	1.5e-07	NA	3.5e-07
9	TCGA	Brain Lower Grade Glioma	0.0820	0.0291	1.3e-08	0.089	0.085	0.093	NA	0.090	2.8e-10	6.2e-10	9.7e-11	NA	2.1e-10
10	TCGA	Lung Adenocarcinoma	0.0634	0.0282	2.9e-05	0.059	0.043	0.038	NA	0.046	1.8e-07	7.6e-06	2.5e-05	NA	4.4e-06
11	TCGA	Lung Squamous Cell Carcinoma	0.0753	0.0288	5.8e-06	0.045	0.063	0.064	NA	0.055	6.6e-06	1.1e-07	9.8e-08	NA	7.2e-07
12	TCGA	Ovarian Serous Cystadenocarcinoma	0.1390	0.0640	7.2e-05	0.017	0.075	0.069	NA	0.057	2.5e-02	8.6e-06	2.1e-05	NA	1.0e-04
13	TCGA	Prostate Adenocarcinoma	0.0744	0.0281	7.6e-07	0.095	0.046	0.061	NA	0.076	4.2e-10	1.2e-05	5.1e-07	NA	2.2e-08
14	TCGA	Testicular Germ Cell Tumors	0.1840	0.0860	3.3e-03	0.100	0.049	0.079	NA	0.049	2.2e-04	8.2e-03	9.3e-04	NA	7.7e-03
15	TCGA	Thyroid Carcinoma	0.0830	0.0290	7.5e-07	0.066	0.085	0.058	NA	0.026	4.8e-07	1.2e-08	2.6e-06	NA	1.4e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Happiness	4.3	5.2	8.1	-2.8	-2.3	-2.8	-1.9	1.9	2.1	2.5	2.4	1.8	2.5	2.8	1.9	2.3	2.5	1.2
Nervous feelings	3.8	7.0	10.4	2.3	2.2	1.5	0.9	-3.2	-3.2	-3.0	-3.0	-3.1	-3.2	-2.6	-2.8	-3.0	-2.3	-2.3
Birth weight	3.8	8.4	17.2	-3.1	-3.0	-4.2	-2.8	1.9	2.6	3.2	3.2	2.5	2.9	2.3	3.1	2.6	3.3	1.8
Shortness of breath walking on level ground	3.8	4.5	10.5	1.1	1.2	2.1	0.8	-2.0	-2.0	-2.4	-1.9	-2.2	-2.6	-1.1	-2.7	-2.9	-3.2	-1.9
Standing height	3.6	35.3	108.2	-4.8	-5.0	-10.4	-4.6	4.3	5.1	6.1	5.8	6.0	6.4	5.0	6.2	6.1	6.5	4.3
Comparative height size at age 10	3.6	19.7	58.7	-3.8	-3.7	-7.7	-3.9	3.0	4.0	4.7	4.3	4.8	4.8	3.8	4.2	4.5	4.7	2.7
Hand grip strength (left)	3.3	8.8	20.7	-3.3	-3.8	-4.5	-3.9	2.0	2.5	2.9	3.5	2.2	2.7	2.7	2.6	2.0	2.9	1.1
Chronotype (morning person)	3.1	7.1	11.3	1.8	1.7	3.3	1.4	-1.8	-3.4	-3.0	-3.0	-2.6	-3.0	-2.2	-3.3	-3.0	-3.3	-2.1
Qualifications: NVQ or HND or HNC or equivalent	3.0	3.6	6.5	1.4	1.1	0.3	1.0	-2.2	-2.5	-2.4	-1.5	-2.5	-2.5	-1.2	-1.4	-2.5	-1.8	-2.5
BMI	2.9	17.1	52.3	3.0	3.0	7.2	3.0	-1.5	-3.8	-3.9	-4.7	-4.4	-4.0	-2.8	-5.1	-4.3	-5.9	-1.0
Hayfever, allergic rhinitis or eczema	2.9	6.2	10.8	-2.8	-2.0	-2.5	-2.2	1.4	2.8	3.0	3.0	1.8	2.6	2.5	2.9	2.3	3.3	1.2
Number of live births	2.8	4.0	9.7	1.0	1.0	-0.1	0.4	-1.9	-2.3	-2.4	-1.9	-3.1	-2.6	-1.2	-2.2	-2.9	-2.5	-1.5
Height	2.7	51.6	225.0	-6.4	-6.6	-15.0	-6.4	3.9	5.5	6.8	6.8	6.9	7.0	5.7	6.6	6.5	7.7	3.7
Medication: Aspirin	2.6	3.5	6.8	-0.6	-0.5	2.0	-2.0	-2.2	-1.9	-1.5	-1.3	-2.3	-2.1	-1.1	-2.5	-2.6	-1.9	-1.9
Medication: Aspirin	2.5	3.2	6.0	-0.8	-0.9	2.2	-2.1	-2.0	-2.0	-1.4	-1.2	-2.0	-1.9	-1.2	-2.4	-2.4	-1.6	-1.7
High blood pressure (mother)	2.4	3.4	8.1	1.7	1.7	1.5	1.9	-0.7	-2.9	-2.1	-2.5	-1.8	-2.0	-2.3	-1.6	-1.5	-1.6	-0.2
Loud music exposure frequency	2.4	2.6	5.1	1.2	1.5	0.6	1.0	-1.2	-2.1	-2.2	-2.3	-1.5	-1.8	-1.5	-2.0	-1.6	-1.6	-0.8
Major Depression (MDD)	2.3	2.8	5.7	-0.8	-0.6	-0.7	-0.8	2.0	1.8	2.2	1.6	2.2	2.2	1.3	1.6	2.4	2.1	1.0
Age at First Birth	2.3	3.4	5.4	-2.1	-2.1	-1.4	-1.5	2.1	1.5	2.0	1.9	1.6	2.1	1.2	2.0	2.1	2.3	1.4
Emphysema/chronic bronchitis	2.3	2.6	5.9	1.1	1.5	1.4	0.9	-1.6	-2.0	-1.7	-2.0	-1.1	-1.7	-1.2	-2.4	-1.6	-1.6	-1.7
Maternal smoking around birth	2.2	3.1	9.3	3.1	2.8	2.2	2.6	-1.1	-0.7	-1.5	-1.8	-1.0	-1.2	-0.9	-1.4	-0.8	-1.9	-1.1
Average weekly red wine intake	2.2	3.3	6.5	-1.2	-1.1	-1.3	-1.1	1.7	2.5	2.5	2.5	1.5	2.1	2.3	2.1	1.8	1.6	0.6
Sitting height	2.0	14.4	36.6	-2.7	-3.0	-6.0	-2.4	2.9	2.9	4.0	3.4	3.6	4.3	3.6	4.2	4.3	4.3	3.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	7.4	-2.4	-1.7	-1.9	-1.8	1.9	0.0	1.9	0.8	1.4	2.0	1.3	1.0	2.3	2.7	1.1
Glaucoma (self-reported)	2.0	2.4	5.3	-0.3	-0.3	-0.1	0.9	1.8	1.6	1.3	1.0	1.9	1.8	2.3	1.5	2.2	1.7	1.9
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	4.5	1.5	1.1	-0.4	0.9	-1.5	-2.1	-1.9	-1.8	-1.7	-1.8	-1.7	-1.3	-1.7	-1.5	-0.7
Schizophrenia vs Biploar Disorder	1.9	2.5	5.3	1.8	1.8	1.8	0.9	-1.7	-1.1	-1.7	-1.8	-0.6	-1.5	-2.3	-1.8	-1.4	-1.6	-1.4
Allergy or Eczema	1.9	5.1	9.1	-2.5	-1.9	-2.4	-2.2	1.0	2.5	2.6	2.8	1.9	2.4	2.0	2.5	2.0	3.0	0.6
Angina	1.9	2.5	6.3	1.3	1.8	1.8	0.7	-1.3	-1.3	-1.2	-1.9	-1.3	-1.3	-0.6	-2.4	-1.7	-2.5	-1.3
Hand grip strength (right)	1.9	5.3	15.9	-3.1	-3.2	-3.6	-4.0	0.7	1.2	1.9	2.6	0.8	1.6	1.5	2.0	1.1	2.6	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.4	9.3	0.5	1.2	0.9	-0.2	-1.5	-2.7	-2.0	-2.5	-2.1	-2.3	-2.8	-3.0	-2.5	-2.5	-2.0
Falls in the last year	1.9	2.5	6.8	-0.3	-0.5	1.3	-0.9	-1.0	-1.7	-1.3	-1.1	-2.1	-1.9	-0.8	-2.6	-2.4	-2.3	-1.2
Hair/balding pattern: Pattern 4	1.9	4.5	9.4	-3.1	-2.3	-1.0	-2.0	2.0	1.8	2.5	2.9	1.7	2.0	1.9	2.4	1.8	2.4	0.7
Angina (self-reported)	1.8	2.4	5.9	1.1	1.7	1.7	0.5	-1.5	-1.4	-1.1	-1.8	-1.2	-1.2	-0.6	-2.4	-1.7	-2.4	-1.4
Illnesses of siblings: Diabetes	1.8	2.2	5.3	1.5	2.3	2.1	1.9	-1.1	-1.5	-1.5	-2.0	-0.2	-1.2	-0.7	-1.9	-0.7	-1.0	-0.9
Leg fat percentage (left)	1.8	6.6	23.8	2.2	2.5	4.9	3.1	-0.5	-1.3	-2.1	-2.6	-1.9	-2.1	-1.1	-3.0	-2.3	-4.1	-0.6
Serious illness, injury or assault of a close relative in last 2 years	1.7	1.9	7.0	-2.5	-2.6	-1.9	-2.6	0.4	0.6	0.9	1.5	-0.5	0.4	0.1	0.8	-0.3	0.2	-0.1
Leg fat percentage (right)	1.7	6.1	23.7	2.3	2.5	4.9	3.3	-0.2	-1.0	-1.9	-2.4	-1.7	-1.8	-0.9	-2.8	-2.0	-4.0	-0.3
Suffer from ‘nerves’	1.7	2.7	5.2	1.5	1.6	0.6	0.9	-1.8	-2.2	-2.0	-2.2	-2.3	-1.9	-1.5	-1.4	-1.6	-1.0	-1.1
Type 2 Diabetes (T2D) (2012)	1.6	1.8	3.0	1.3	1.3	1.6	1.1	-0.9	-1.0	-1.6	-1.6	-1.0	-1.4	-1.2	-1.7	-1.5	-1.7	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.5	8.5	1.4	2.1	1.5	1.3	-1.1	-1.8	-1.9	-2.5	-1.1	-1.7	-1.8	-2.9	-1.8	-2.4	-2.0
Body mass index (BMI)	1.6	6.7	27.5	1.4	1.6	5.2	2.0	-0.2	-2.1	-2.2	-2.8	-2.5	-2.2	-1.1	-3.4	-2.6	-4.0	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.4	6.9	-0.8	-0.3	-0.6	-2.0	-2.5	-2.1	-1.4	-1.1	-2.5	-2.0	-2.3	-1.8	-2.4	-1.1	-2.6
Sensitivity / hurt feelings	1.5	2.6	6.2	0.7	0.9	-0.1	0.0	-1.8	-2.3	-1.9	-1.8	-1.6	-1.8	-2.5	-1.8	-1.6	-0.8	-1.9
Birth weight of first child	1.5	2.8	14.0	-1.6	-1.3	-3.7	-1.6	0.9	0.9	1.7	1.3	1.1	1.7	1.4	1.6	1.4	1.9	0.9
Arm fat percentage (left)	1.5	6.1	26.7	1.5	1.8	5.2	2.3	-0.4	-1.8	-2.0	-2.7	-2.5	-2.1	-0.8	-3.2	-2.3	-3.6	-0.2
Ulcerative Colitis (UC)	1.4	2.6	4.8	-2.0	-2.2	-1.9	-1.9	1.2	1.4	1.7	1.9	1.4	1.7	1.0	1.3	1.4	1.6	0.8
Hypothyroidism (self reported)	1.4	3.2	7.0	1.3	1.4	-0.0	0.8	-2.0	-2.0	-2.1	-1.9	-2.6	-2.2	-1.1	-2.4	-1.9	-1.9	-1.6
Relative age of first facial hair	1.4	2.9	4.9	1.7	2.2	1.0	1.1	-2.1	-1.9	-1.9	-2.0	-2.0	-1.8	-2.0	-1.0	-1.4	-1.1	-1.5
Severe depression (siblings)	1.4	1.6	3.6	-1.0	-0.5	-1.1	-1.1	0.6	1.3	1.6	1.1	1.1	1.5	1.7	1.2	1.6	1.9	0.6
Arm fat percentage (right)	1.4	5.4	22.7	1.3	1.5	4.8	1.9	-0.4	-1.7	-1.8	-2.4	-2.5	-2.0	-0.6	-3.2	-2.3	-3.6	-0.3
Medication: Blood pressure	1.4	2.5	5.0	0.3	0.3	0.9	-0.0	-1.8	-2.0	-1.6	-1.5	-2.1	-2.0	-0.7	-2.0	-2.2	-1.8	-1.9
Average weekly beer plus cider intake	1.4	2.0	4.2	1.1	1.0	0.5	1.0	-1.2	-2.0	-1.9	-2.0	-1.2	-1.5	-1.6	-1.7	-1.2	-1.3	-0.9
Diastolic blood pressure, automated reading	1.4	4.4	10.2	1.7	1.8	3.2	1.5	-1.5	-1.8	-1.9	-1.9	-2.2	-2.2	-1.8	-2.5	-2.3	-3.0	-1.3
Myopia	1.4	2.0	6.6	2.4	2.6	1.6	2.2	-0.6	0.2	-1.4	-1.1	-0.8	-1.3	-1.4	-0.5	-0.9	-1.5	-0.1
Alcohol drinker status: Previous	1.4	1.6	3.1	0.8	0.8	1.4	0.4	-1.6	-1.4	-1.3	-1.3	-1.3	-1.4	-0.9	-1.2	-1.4	-1.3	-1.8
Schizophrenia (2018)	1.3	2.6	6.1	2.2	1.4	0.9	1.5	-1.8	-1.6	-2.0	-1.9	-1.0	-1.5	-2.5	-1.5	-1.2	-1.2	-1.2
Prostate Cancer	1.3	1.8	5.0	1.0	0.1	1.1	-0.0	-1.6	-0.6	-1.1	-0.3	-1.4	-1.5	-1.0	-1.5	-1.9	-2.2	-2.2
HbA1C	1.3	1.4	3.1	-0.7	-0.8	-0.9	-0.8	1.0	1.2	1.3	0.8	1.8	1.6	1.0	0.5	1.7	1.7	1.1
Forced vital capacity (FVC)	1.3	5.1	32.0	-2.2	-2.5	-5.7	-2.9	0.4	0.6	1.7	1.6	0.9	1.7	0.9	2.0	1.5	2.5	0.9
Trunk fat-free mass	1.3	7.5	15.9	-3.1	-3.3	-4.0	-2.9	2.9	1.8	2.9	2.4	2.4	3.0	2.5	2.1	2.5	2.2	2.4
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	3.4	-1.2	-1.1	-0.9	-0.7	1.8	1.4	1.3	1.1	1.0	1.4	1.2	1.3	1.3	1.2	1.7
Depression (self-reported)	1.3	1.6	6.9	-0.3	0.6	0.2	-0.5	-0.6	-2.6	-0.8	-2.1	-1.5	-1.1	-1.0	-2.1	-1.0	-0.7	-0.1
Trunk predicted mass	1.3	7.5	16.0	-3.1	-3.3	-4.0	-2.9	2.9	1.8	2.8	2.4	2.4	3.0	2.5	2.0	2.5	2.2	2.4
Worry too long after embarrassment	1.3	2.2	6.6	0.1	1.3	0.8	-0.2	-1.5	-2.6	-1.4	-1.9	-1.5	-1.6	-2.0	-1.7	-1.4	-0.4	-1.5
Average weekly champagne plus white wine intake	1.3	1.8	3.1	-1.0	-0.9	-0.1	-0.2	1.7	1.5	1.5	1.2	1.4	1.6	1.4	1.2	1.8	1.4	1.6
Mother’s age at death	1.3	1.7	5.7	-0.8	-0.8	-1.4	-0.7	0.6	1.1	1.1	1.4	0.5	1.1	0.7	2.4	1.5	2.4	1.0
Unable to work because of sickness or disability	1.3	1.7	4.1	-0.6	0.2	1.0	-0.7	-1.6	-1.1	-1.1	-0.8	-1.3	-1.5	-1.1	-1.8	-2.0	-1.4	-1.9
Verbal and Numeric Reasoning (VNR)	1.2	2.9	4.6	1.9	2.1	2.0	1.6	-1.6	-1.6	-1.8	-1.8	-1.5	-1.9	-1.8	-1.1	-1.6	-1.6	-1.0
Relative age voice broke	1.2	1.8	4.5	1.0	1.1	0.7	0.9	-1.5	-1.9	-1.5	-1.6	-2.1	-1.6	-1.1	-1.0	-1.5	-1.1	-0.6
Hearing difficulty/problems with background noise	1.2	1.8	5.8	1.7	1.8	1.2	2.4	-0.3	-1.3	-1.5	-2.0	-1.0	-1.0	-0.9	-1.0	-0.5	-1.0	1.0
Body fat percentage	1.2	4.6	17.9	1.6	2.0	4.2	2.5	-0.2	-1.2	-1.6	-2.3	-2.0	-1.7	-0.5	-2.7	-1.9	-3.4	-0.0
Eye problems/disorders: None of the above	1.2	1.4	2.6	-0.8	-0.8	-1.1	-0.8	0.8	1.4	1.6	1.2	1.4	1.6	1.0	1.2	1.4	1.0	1.0
Supplements: Fish oil (including cod liver oil)	1.2	1.6	4.1	-1.5	-1.6	-2.0	-1.3	0.9	0.6	1.2	1.2	0.9	1.2	1.0	1.0	1.3	1.6	0.8
Medication: Paracetamol	1.2	1.9	4.0	1.5	1.2	1.8	1.8	-0.0	-1.2	-1.4	-2.0	-0.4	-1.0	-1.3	-1.9	-0.9	-1.9	0.6
Schizophrenia (2014)	1.1	2.5	5.7	2.4	2.0	0.7	1.9	-1.5	-1.4	-1.7	-2.0	-0.8	-1.2	-2.3	-1.4	-1.0	-1.0	-1.0
Ulcerative Colitis	1.1	1.6	4.8	-1.9	-2.0	-2.2	-2.2	0.3	0.4	1.1	1.3	0.3	0.8	0.5	0.7	0.5	1.1	-0.1
Heel T-Score	1.1	8.7	14.8	2.0	2.4	3.1	1.6	-2.1	-2.7	-3.1	-3.2	-3.3	-3.3	-2.8	-3.7	-3.4	-3.9	-2.8
Lung FEV1/FVC ratio	1.1	5.4	7.7	1.8	2.5	2.8	1.1	-2.0	-1.9	-2.5	-2.7	-2.2	-2.5	-2.5	-2.6	-2.5	-2.7	-2.0
Hearing difficulty/problems: Yes	1.1	1.8	7.5	1.8	2.0	1.6	2.7	0.1	-0.7	-1.2	-1.8	-0.6	-0.7	-0.2	-1.0	-0.4	-1.2	0.6
Average weekly fortified wine intake	1.1	1.3	2.7	-0.3	-0.6	-1.4	-0.1	0.7	1.6	1.0	1.5	1.6	1.2	1.4	1.4	1.2	1.2	0.8
Medication for cholesterol, blood pressure or diabetes	1.1	1.7	3.8	-0.2	-0.2	-0.6	0.1	1.4	1.5	1.4	1.1	1.5	1.7	0.6	2.0	1.9	1.7	1.7
Pulse wave peak to peak time	1.1	1.3	5.8	-1.6	-2.1	-1.4	-2.4	0.3	0.3	0.7	1.4	-0.2	0.4	-0.3	1.0	0.1	1.1	-0.1
Mineral and other dietary supplements	1.1	1.5	5.7	1.7	2.1	2.4	1.8	-0.1	-0.1	-0.8	-1.1	0.2	-0.6	-0.8	-1.0	-0.6	-1.4	-0.5
Worry (Nagel 2018)	1.0	2.1	3.4	1.7	1.7	-0.3	0.8	-1.8	-1.8	-1.6	-1.7	-1.7	-1.7	-1.4	-1.1	-1.4	-0.7	-1.1
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.8	-0.2	-0.0	0.8	-0.4	-0.9	-1.2	-1.1	-0.6	-1.7	-1.5	-0.4	-1.2	-1.6	-0.8	-1.1
Medication: Metformin	1.0	1.4	4.6	-0.9	-0.6	0.2	-0.4	1.6	1.6	1.3	1.2	0.6	1.1	2.1	1.1	1.0	1.0	1.5
Pack years adult smoking proportion	1.0	1.5	3.5	1.2	1.4	1.4	1.4	-1.0	-0.3	-1.1	-0.9	-1.1	-1.1	-0.5	-1.6	-1.2	-1.9	-1.1
Number of self-reported non-cancer illnesses	1.0	1.7	7.6	-2.8	-2.1	-0.6	-1.8	1.0	0.8	1.5	1.6	0.3	0.9	1.6	0.4	0.3	0.3	-0.1
Medication: Atorvastatin	1.0	1.3	3.5	-1.5	-1.2	0.2	-1.9	-1.0	-0.7	-0.5	0.3	-1.4	-1.2	-0.4	-1.0	-1.7	-0.9	-1.3
Pack years of smoking	1.0	1.4	3.3	1.2	1.3	1.4	1.3	-1.1	-0.4	-1.1	-0.9	-1.2	-1.2	-0.7	-1.4	-1.3	-1.8	-1.1
Neuroticism (Nagel 2018)	0.9	2.1	5.4	1.0	0.9	0.2	0.2	-1.8	-2.3	-1.7	-1.6	-1.9	-1.9	-1.4	-1.4	-1.6	-0.7	-1.0
Blood White Count	0.9	6.7	16.4	2.1	1.9	4.0	2.2	-1.8	-1.8	-2.8	-2.2	-2.9	-3.0	-2.4	-2.2	-3.0	-3.5	-1.6
Supplements: Zinc	0.9	1.0	4.6	-1.4	-1.3	-2.1	-1.9	0.2	-0.5	0.6	0.2	0.3	0.4	-0.5	0.2	0.3	0.9	1.1
Multivitamins +/- minerals	0.9	1.1	4.2	-1.6	-1.8	-1.5	-2.1	0.3	-0.7	0.7	0.5	0.8	0.6	-0.1	-0.0	0.8	1.2	0.1
Had other major operations	0.9	1.0	4.4	-0.5	-0.6	-0.9	-0.1	0.7	1.2	1.0	1.5	0.2	0.9	0.9	2.1	0.9	1.1	1.1
Peak expiratory flow (PEF)	0.9	2.0	15.8	-1.9	-1.4	-4.0	-2.7	-0.3	-0.4	0.3	0.3	-0.7	-0.1	-0.2	0.2	-0.7	0.2	0.1
Leg fat mass (right)	0.9	3.5	13.0	1.3	1.4	3.6	2.1	0.1	-1.0	-1.4	-1.9	-1.4	-1.3	-0.5	-2.5	-1.7	-3.4	0.1
Overall health rating	0.9	1.9	5.5	0.1	0.4	2.1	-0.1	-1.1	-0.7	-1.1	-0.7	-1.7	-1.6	-1.0	-1.5	-2.1	-2.3	-1.1
Chest pain or discomfort	0.9	1.3	4.1	1.2	1.3	2.0	1.3	-1.0	-0.5	-1.2	-1.2	-0.7	-0.9	-1.0	-1.0	-1.0	-1.5	-0.7
Had major operations	0.9	1.0	2.2	-0.9	-1.1	-1.4	-0.6	0.5	1.5	1.2	1.5	0.9	1.1	0.8	1.1	0.8	0.6	0.3
Knee pain experienced in last month	0.9	1.4	5.9	-2.3	-1.8	-1.1	-2.4	0.2	-1.2	-0.1	-0.0	-1.7	-0.5	0.2	-0.6	-0.9	0.3	-0.1
Whole body fat-free mass	0.9	5.1	9.5	-3.0	-3.1	-3.0	-2.8	2.7	1.1	2.3	1.8	1.7	2.4	2.1	1.3	1.9	1.6	2.2
Eye problems/disorders: Cataract	0.9	1.1	2.4	0.1	0.8	1.5	0.3	-0.6	-0.9	-0.9	-0.6	-1.2	-1.4	-1.6	-0.9	-1.4	-1.3	-0.9
Osteoarthritis (self-reported)	0.9	1.2	6.1	-2.0	-1.6	-1.2	-2.5	0.3	0.3	1.1	1.0	0.5	0.7	0.7	-0.1	0.1	0.5	-0.2
Risk taking	0.9	1.3	3.0	-1.4	-1.2	-0.6	-0.9	1.5	0.8	1.0	0.8	0.2	1.1	1.2	1.2	1.2	1.7	1.5
Ever depressed for a whole week	0.9	1.2	5.1	-2.1	-1.5	-1.1	-2.3	0.7	0.3	0.9	0.7	-0.2	0.7	0.4	0.3	0.6	1.3	0.1
Leg fat mass (left)	0.9	3.6	12.3	1.2	1.4	3.5	1.9	0.0	-1.2	-1.5	-2.0	-1.4	-1.4	-0.6	-2.6	-1.8	-3.4	-0.1
Intelligence (Savage-Jansen 2018)	0.8	2.5	4.1	1.3	1.9	1.2	0.5	-1.9	-1.7	-1.9	-1.5	-1.4	-2.0	-1.6	-1.5	-1.8	-1.4	-1.7
Lung FVC	0.8	4.3	13.7	-1.9	-2.0	-3.7	-3.4	-2.5	-1.5	-0.8	0.0	-2.7	-1.6	-0.9	-0.6	-2.4	-0.4	-2.4
Ever used hormone-replacement therapy (HRT)	0.8	1.1	1.7	1.2	1.1	0.4	1.0	-1.0	-1.2	-1.3	-1.3	-1.0	-1.2	-0.9	-0.7	-1.1	-1.3	-0.1
Diabetes (father)	0.8	1.0	1.9	1.0	0.9	1.1	1.2	-0.2	-0.8	-1.1	-1.3	-0.6	-0.9	-1.1	-1.4	-0.9	-1.3	-0.6
Time employed in main current job	0.8	1.0	3.1	-0.9	-0.1	0.3	-0.1	0.8	1.5	1.2	1.0	0.3	1.1	1.8	1.2	1.0	1.0	0.5
Gout (self-reported)	0.8	1.1	4.2	-2.0	-1.7	0.2	-1.5	0.4	-1.4	-0.4	-0.4	-1.6	-0.4	0.5	-1.1	-0.6	0.0	-0.1
Forced vital capacity (FVC), Best measure	0.8	2.9	27.5	-1.4	-1.9	-5.2	-2.6	-0.7	-0.2	0.5	0.7	0.2	0.4	-0.1	0.8	0.2	1.3	0.0
Medication: Seretide 50 evohaler	0.8	1.0	5.2	-1.4	-1.0	-1.0	-2.3	-0.7	0.5	0.7	1.0	-0.8	0.0	-0.4	0.4	-0.4	0.3	-1.3
Medication for cholesterol	0.8	1.2	2.7	1.4	1.7	1.3	1.3	-0.4	-0.7	-1.2	-1.1	-0.8	-1.1	-1.2	-0.4	-1.0	-1.2	-0.3
Medication: Gliclazide	0.8	0.9	2.2	0.4	1.0	1.3	0.4	-1.2	-0.3	-1.0	-0.5	-1.5	-1.2	-0.4	-0.5	-1.3	-0.8	-1.0
Whole body water mass	0.8	4.5	8.4	-2.8	-2.9	-2.8	-2.6	2.5	1.0	2.1	1.6	1.6	2.3	2.0	1.1	1.8	1.4	2.1
Fractured/broken bones in last 5 years	0.8	1.0	3.9	-0.4	-0.2	-2.0	-0.2	0.6	1.3	0.9	0.9	-0.5	0.7	1.4	1.5	0.7	1.0	1.0
Mean Putamen Volume	0.7	0.8	1.8	-0.2	0.0	-0.6	0.1	1.1	0.8	0.9	0.7	1.2	1.1	-0.0	1.4	1.3	1.2	1.1
Fasting Glucose	0.7	0.8	2.7	0.7	1.0	0.4	0.1	-1.1	-0.7	-0.8	-1.0	-1.6	-1.1	-1.2	-0.5	-0.9	-0.5	-0.5
HDL Cholesterol	0.7	1.2	2.8	0.3	0.1	0.4	-0.7	-1.3	-1.3	-1.1	-1.0	-1.3	-1.2	-1.7	-1.3	-1.5	-1.1	-1.1
Rheumatoid Arthritis	0.7	0.9	2.6	-0.0	-0.4	-0.5	-0.4	-0.5	-1.6	-1.3	-1.2	-1.3	-1.0	-0.6	-1.3	-1.2	-0.7	-0.5
Frequency of depressed mood in last 2 weeks	0.7	1.0	3.4	-1.8	-1.4	-0.9	-1.9	0.6	-0.4	0.8	0.5	-0.6	0.5	0.8	0.4	0.5	1.3	0.5
Trunk fat percentage	0.7	2.8	11.2	1.2	1.6	3.3	2.1	0.2	-0.9	-1.1	-1.8	-1.6	-1.2	-0.1	-2.0	-1.4	-2.6	0.4
Medication: Ramipril	0.7	0.9	4.6	-2.0	-1.3	0.4	-2.1	0.6	0.3	0.8	0.7	-0.8	0.2	0.2	0.1	-0.1	0.5	-0.1
Mouth/teeth dental problems: Dentures	0.7	1.1	2.9	1.2	0.8	1.7	0.9	-0.5	-1.0	-1.3	-1.3	-0.6	-1.1	-0.8	-1.1	-1.1	-1.2	0.4
Prospective memory result	0.7	0.8	2.4	0.2	0.2	-0.8	0.4	1.5	1.0	0.7	0.4	0.8	1.0	1.1	0.8	1.1	0.8	1.5
Lung cancer (father)	0.7	0.9	3.9	1.1	1.2	1.6	2.0	0.5	0.7	-0.3	-0.3	0.6	0.0	-0.0	0.1	0.4	-0.2	1.5
Pulse wave Arterial Stiffness index	0.7	0.8	4.0	1.1	1.7	0.8	2.0	0.0	0.0	-0.3	-1.0	0.7	0.1	0.6	-0.6	0.3	-0.5	0.4
Exposure to tobacco smoke at home	0.7	0.8	2.0	-0.7	-0.4	-1.0	-1.3	-1.1	-1.1	-0.6	-0.4	-1.4	-1.1	-0.6	-0.8	-1.3	-0.2	-0.8
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	3.8	0.5	0.2	-0.9	-0.0	-1.6	-1.6	-1.2	-1.3	-1.6	-1.3	-0.7	-1.9	-1.2	-1.2	-0.9
Medication: Allopurinol	0.7	0.9	3.3	-1.8	-1.7	0.3	-1.2	0.7	0.5	0.8	1.1	-0.4	0.5	1.5	0.4	0.3	0.6	0.3
Alcohol intake frequency.	0.7	1.6	4.7	1.0	1.2	1.8	0.8	-0.8	-1.7	-1.4	-2.2	-0.4	-1.0	-0.7	-2.0	-0.9	-1.3	-0.3
Number of full sisters	0.7	0.9	4.6	-0.0	0.3	-0.6	-1.0	-1.0	-0.9	-0.7	-0.4	-2.2	-1.0	-0.7	-0.1	-1.3	-0.4	-1.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	3.2	1.1	1.5	0.1	1.8	0.4	-0.1	0.1	-0.9	0.6	0.6	0.9	0.5	1.2	1.0	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	9.6	-1.3	-1.4	-3.1	-1.6	0.6	0.6	1.0	1.0	1.0	0.9	0.2	0.7	0.8	0.9	0.5
Handedness (chirality/laterality): Left-handed	0.7	0.8	3.8	0.2	0.6	0.1	-0.1	-1.1	-0.6	-0.5	-0.6	-1.0	-0.8	-0.3	-1.0	-1.2	-1.1	-1.9
Loneliness, isolation	0.7	1.0	4.0	-1.7	-1.3	-1.5	-2.0	0.4	-0.4	0.8	0.5	0.1	0.6	0.5	0.2	0.6	1.3	0.4
Arm fat mass (left)	0.7	2.9	11.9	0.7	0.9	3.5	1.4	0.2	-1.4	-1.2	-2.0	-1.7	-1.2	-0.2	-2.5	-1.6	-2.9	0.2
Irritable Bowel Disease (IBD)	0.6	1.3	2.5	-1.4	-1.6	-1.1	-1.2	1.1	1.0	1.3	1.3	1.0	1.4	0.9	0.8	1.1	1.0	1.0
Waist Hip Ratio (WHR)	0.6	2.5	8.2	-1.4	-1.0	-2.9	-0.8	1.8	0.8	1.6	0.9	2.1	1.8	0.2	1.4	1.9	1.7	1.8
Vitamin and mineral supplements	0.6	0.8	2.2	1.1	1.3	1.0	1.5	-0.1	1.1	-0.7	0.1	-0.2	-0.6	-0.2	0.1	-0.8	-1.4	-0.6
Medication: Co-codamol	0.6	0.7	2.2	1.2	1.3	1.5	1.3	-0.2	-0.1	-0.5	-0.5	0.2	-0.5	0.2	-0.9	-0.5	-1.2	-0.1
Supplements: Glucosamine	0.6	0.8	3.5	-1.3	-1.8	-1.9	-1.2	0.2	-0.4	0.6	0.5	0.0	0.5	0.3	0.2	0.4	0.6	0.5
Hair/balding pattern: Pattern 3	0.6	0.9	3.0	1.7	0.9	1.6	1.4	-0.8	0.2	-0.8	-0.6	0.3	-0.4	-0.1	-0.5	-0.5	-1.0	-1.0
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	17.8	-1.4	-1.5	-4.2	-2.4	-0.3	-0.1	0.6	0.6	-0.2	0.5	-0.2	1.0	0.3	1.2	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	16.6	-1.0	-1.4	-4.1	-2.3	-0.9	-0.7	-0.1	0.1	-0.4	-0.2	-0.9	0.1	-0.3	0.6	-0.2
Arm fat mass (right)	0.6	2.6	11.5	0.6	0.7	3.4	1.3	0.4	-1.1	-1.0	-1.7	-1.6	-1.1	-0.0	-2.4	-1.4	-2.8	0.4
High blood pressure (siblings)	0.6	0.8	2.2	-0.9	-0.7	0.6	0.3	1.5	1.1	0.9	0.9	1.1	1.0	1.0	0.5	1.0	0.6	0.8
Leg pain on walking	0.6	0.8	2.3	-0.5	0.2	0.0	-0.8	-0.7	-0.9	-0.6	-0.6	-1.5	-1.0	-0.7	-0.5	-1.4	-0.9	-1.3
Supplements: Vitamin C	0.6	0.8	2.0	-1.3	-1.4	-0.6	-1.3	0.4	-0.2	0.8	0.1	0.1	0.9	0.4	0.2	0.6	1.2	1.4
Leg fat-free mass (right)	0.6	3.2	9.2	-3.0	-2.9	-1.8	-2.9	2.1	0.0	1.6	1.0	0.7	1.5	1.4	0.4	1.0	1.1	1.9
Leg predicted mass (right)	0.6	3.1	9.1	-3.0	-2.9	-1.8	-2.9	2.0	0.0	1.6	0.9	0.6	1.5	1.4	0.3	0.9	1.0	1.8
Eye problems/disorders: Glaucoma	0.6	0.7	2.9	0.4	0.3	-0.0	1.5	0.9	0.6	0.3	0.2	0.3	0.7	1.7	0.8	1.1	0.8	1.1
Illnesses of father: High blood pressure	0.6	0.7	2.4	-1.2	-1.2	-0.4	-0.8	0.9	0.1	0.4	0.7	0.7	0.6	-0.4	0.9	0.9	1.6	0.4
Basal metabolic rate	0.6	3.3	6.0	-2.4	-2.5	-2.2	-2.1	2.4	0.8	1.8	1.2	1.2	1.9	1.8	0.9	1.4	1.0	2.1
Number of operations (self-reported)	0.6	0.9	3.3	-1.5	-1.1	-1.8	-1.1	0.5	0.7	0.9	1.1	-0.3	0.5	1.3	0.8	0.1	0.3	0.2
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.2	-1.5	-1.2	-1.4	-1.5	0.2	-0.3	0.8	0.6	-0.3	0.2	0.4	0.6	0.0	0.7	0.5
Heart disease (siblings)	0.6	0.7	1.8	-0.9	-0.9	-0.9	-0.4	1.4	0.5	0.8	0.3	1.0	0.9	1.0	-0.2	1.0	0.6	1.3
Bipolar Disorder or Schizophrenia	0.5	1.2	4.7	1.5	1.1	0.1	1.2	-1.2	-1.1	-1.2	-1.3	-0.6	-0.9	-2.2	-0.8	-0.6	-0.3	-0.9
Alzheimer’s Disease (including proxy)	0.5	0.7	2.2	-1.5	-0.9	-1.2	-1.2	0.2	0.9	0.8	1.0	0.2	0.6	0.4	0.7	0.5	0.7	-0.6
Breast Cancer	0.5	1.2	2.5	-1.5	-1.6	-1.6	-1.3	0.4	1.0	1.0	1.4	0.6	0.9	0.8	1.3	0.6	0.8	0.4
Blood Red Count	0.5	5.1	15.0	0.6	1.1	-0.9	-0.1	-2.8	-2.8	-2.1	-2.3	-3.9	-2.6	-1.5	-2.6	-2.8	-2.4	-2.1
Number of treatments/medications taken	0.5	1.0	3.2	-1.6	-1.4	-1.3	-1.4	0.5	-0.1	0.9	0.3	-0.0	0.7	1.8	-0.2	0.5	0.9	0.5
Diabetes (mother)	0.5	0.6	2.5	-0.9	-1.0	-0.5	-1.6	-0.8	-0.1	0.0	0.7	-0.9	-0.5	-0.0	-0.0	-0.9	-0.2	-1.1
Impedance of leg (right)	0.5	2.2	6.1	2.2	2.2	-2.0	2.5	-0.4	2.1	0.6	0.8	1.6	0.8	0.1	1.6	1.3	0.7	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	2.1	0.3	0.2	-0.1	-0.3	-0.6	-1.5	-0.7	-1.3	-1.2	-0.7	-0.8	-1.3	-0.5	-0.3	-0.3
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.2	-1.5	-1.2	-1.1	-1.5	-0.0	-0.3	0.4	0.3	0.2	0.3	-0.2	0.4	0.2	1.1	-0.6
Leg predicted mass (left)	0.5	2.5	7.0	-2.6	-2.6	-1.4	-2.4	2.1	0.1	1.4	0.8	0.6	1.4	1.4	0.2	0.9	0.8	1.9
Hair/balding pattern: Pattern 2	0.5	0.6	1.9	0.6	0.7	0.3	-0.1	-0.3	-0.8	-0.9	-1.2	-1.4	-0.8	-1.0	-0.9	-0.7	-0.6	-0.2
Impedance of arm (right)	0.5	2.3	7.6	-0.7	-0.4	-2.8	-0.6	0.2	1.7	1.6	1.6	1.1	1.4	1.6	1.8	1.6	2.3	0.7
Pulse rate	0.5	0.9	1.9	0.2	0.4	1.3	-0.1	-1.2	-0.5	-0.7	-0.5	-1.4	-1.1	-0.5	-1.1	-1.4	-1.1	-1.3
Asthma	0.5	1.0	2.3	0.2	0.2	1.1	0.2	-0.9	-0.6	-1.0	-0.4	-0.3	-1.1	-1.5	-1.5	-1.3	-1.5	-1.4
Medication: Lansoprazole	0.5	0.6	1.2	-0.5	-0.6	-0.7	-0.4	1.1	0.6	0.9	0.4	1.0	0.9	0.6	0.7	1.0	0.6	1.0
Illnesses of mother	0.5	0.6	1.9	-0.5	-0.5	-0.6	-0.3	0.4	1.4	0.8	1.0	1.2	0.7	1.2	0.5	0.3	-0.0	0.0
Medication: Paracetamol	0.5	0.8	2.5	0.5	0.3	1.0	0.7	0.5	-0.6	-0.8	-1.4	-0.1	-0.5	-0.9	-1.6	-0.7	-1.5	0.7
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.3	0.3	0.5	1.1	0.3	-0.6	-0.6	-0.8	-0.5	-1.0	-0.9	-0.4	-1.0	-1.0	-0.9	-0.5
Medication for pain relief, constipation, heartburn	0.5	0.8	2.8	0.5	0.3	-1.1	0.6	0.0	1.1	0.8	1.1	0.8	0.9	0.5	1.7	1.2	1.3	0.0
Medication: Ibuprofen	0.5	0.5	2.4	-0.5	-0.5	0.0	0.1	1.4	0.4	0.5	0.2	0.7	0.8	0.4	0.5	0.8	0.7	1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.2	0.8	1.2	0.6	0.7	-0.4	-0.7	-0.5	-0.7	-0.2	-0.5	-0.2	-1.5	-0.6	-0.7	-1.3
Whole body fat mass	0.5	2.1	8.0	0.7	0.9	2.8	1.5	0.5	-0.8	-0.8	-1.6	-1.1	-0.8	0.1	-2.2	-1.1	-2.7	0.5
Family relationship satisfaction	0.5	0.6	1.3	-0.2	-0.2	-0.1	0.6	0.7	0.8	0.6	0.6	0.7	1.0	1.2	0.9	1.1	1.1	0.8
Long-standing illness, disability or infirmity	0.5	0.7	2.5	-0.5	0.4	0.5	-0.5	-1.4	-0.3	-0.3	-0.2	-1.1	-0.8	0.6	-0.6	-1.3	-0.9	-1.6
Guilty feelings	0.5	0.8	3.4	-1.4	-1.6	-1.0	-1.8	0.0	-1.1	0.2	0.1	-0.1	0.1	-0.2	-0.2	0.1	1.3	-0.3
Arm fat-free mass (left)	0.5	2.5	5.2	-1.9	-2.0	-2.1	-1.6	2.3	0.8	1.6	1.0	1.2	1.8	1.7	0.7	1.3	0.5	2.0
Supplements: Calcium	0.5	0.6	3.4	-1.2	-0.9	-1.8	-1.4	-0.4	-0.5	0.3	0.1	-0.1	0.1	0.1	0.2	0.1	0.7	0.5
Basal cell carcinoma (self-reported)	0.5	0.6	3.2	0.9	1.4	0.7	1.8	0.6	0.4	-0.7	-0.5	0.4	-0.2	0.1	-0.1	-0.0	-0.7	0.6
Alzheimer’s Disease (in father)	0.4	0.5	1.4	-0.3	0.2	0.7	0.0	-0.6	-0.8	-0.9	-0.9	-0.7	-0.7	-0.1	-1.2	-0.7	-0.7	-0.7
Triglycerides	0.4	0.6	1.5	0.7	0.5	0.7	0.5	-0.4	-1.1	-0.8	-0.8	-1.0	-1.0	-0.5	-1.0	-0.9	-1.2	0.0
Neuroticism	0.4	1.0	4.2	0.4	0.7	-0.9	-0.3	-1.3	-2.0	-0.8	-1.3	-0.9	-0.9	-1.0	-1.1	-0.7	0.1	-1.1
Leg fat-free mass (left)	0.4	2.3	6.6	-2.6	-2.6	-1.5	-2.4	1.9	-0.0	1.4	0.7	0.5	1.3	1.3	0.2	0.8	0.7	1.8
Fed-up feelings	0.4	0.7	2.7	-0.3	-0.5	-0.3	0.1	1.2	0.3	0.6	0.2	1.1	1.0	0.5	0.7	1.2	1.0	1.6
Taking other prescription medications	0.4	0.6	2.7	-1.6	-1.0	-1.0	-1.1	0.2	-0.2	0.7	0.3	-0.6	0.3	1.1	-0.1	-0.1	0.3	0.1
Age when periods started (menarche)	0.4	1.0	3.7	-0.8	-0.8	-1.9	-1.2	-0.3	0.5	0.6	1.0	0.1	0.6	0.2	1.4	0.7	1.7	-0.8
Medication: Atenolol	0.4	0.5	1.6	0.6	0.2	-0.3	-0.1	-0.5	-1.1	-0.7	-1.2	-0.4	-0.5	-0.7	-1.3	-0.7	-0.9	-0.3
Impedance of leg (left)	0.4	1.9	5.1	1.8	1.9	-2.2	1.9	-0.5	1.9	0.5	0.8	1.5	0.7	-0.1	1.6	1.1	0.7	-0.3
Alcohol usually taken with meals	0.4	0.7	2.4	0.3	0.8	-0.3	0.5	-0.1	1.5	0.9	1.0	1.2	0.8	0.8	0.9	0.9	0.8	-0.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	4.3	-0.4	0.1	-2.1	-0.3	-0.4	0.5	0.4	0.5	0.6	0.5	0.5	0.7	0.6	1.2	-0.1
Medication: Simvastatin	0.4	0.7	1.4	1.0	1.0	0.7	0.9	-0.8	-0.2	-0.9	-0.7	-0.8	-0.9	0.3	-0.5	-0.9	-1.2	-0.6
Illnesses of siblings	0.4	0.6	2.2	0.5	0.2	-0.2	-0.4	-1.5	-0.4	-0.6	-0.0	-1.2	-0.8	-0.6	0.2	-1.0	-0.5	-1.3
Neuroticism score	0.4	0.9	4.7	-0.2	0.2	-0.4	-0.4	-0.8	-2.2	-0.8	-1.3	-1.0	-0.8	-1.4	-1.0	-0.5	0.5	-0.6
Noisy workplace	0.4	0.5	1.9	0.1	0.0	-1.4	0.6	0.5	0.8	0.4	0.3	1.1	0.8	0.5	0.8	1.0	0.5	0.5
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.9	-1.4	-0.9	-0.2	-1.4	0.7	-0.4	0.2	0.1	-1.0	0.2	0.3	-0.2	0.3	1.1	0.6
Blood clot in the leg (DVT)	0.4	0.5	1.0	0.4	0.7	0.4	-0.0	-0.8	-0.7	-0.7	-0.7	-0.2	-0.7	-0.8	-1.0	-0.8	-1.0	-0.9
Arm fat-free mass (right)	0.4	2.2	4.2	-1.9	-2.0	-1.9	-1.8	2.0	0.6	1.4	0.9	1.2	1.7	1.3	0.6	1.2	0.6	1.7
Comparative body size at age 10	0.4	1.2	3.9	-0.5	-0.5	1.3	0.0	2.0	1.3	1.1	0.9	1.1	1.1	0.9	0.7	1.2	0.7	1.6
Wheeze or whistling in the chest in last year	0.4	0.7	3.3	-1.8	-1.2	-0.7	-1.1	1.3	0.1	0.8	0.5	0.3	0.6	0.4	-0.1	0.4	0.3	0.6
Mean time to correctly identify matches	0.4	0.8	2.7	1.1	1.6	0.8	1.3	-1.1	0.5	-0.5	-0.5	-0.4	-0.4	0.2	-0.6	-0.5	-0.8	-1.6
Heart disease (mother)	0.4	0.4	1.7	0.8	0.7	-0.0	0.4	-0.7	-0.5	-0.7	-0.6	0.6	-0.5	-0.4	-1.3	-0.3	-0.7	-0.5
Arm predicted mass (right)	0.4	1.9	4.0	-1.7	-1.8	-2.0	-1.5	1.9	0.5	1.3	0.7	1.2	1.6	1.2	0.6	1.2	0.6	1.6
Smoking status: Previous	0.4	0.6	2.8	-0.8	-0.8	-1.7	-0.4	0.5	-0.6	0.4	0.3	0.5	0.5	0.9	0.8	0.5	1.3	0.4
Commuting to job workplace: Walk	0.4	0.4	2.2	0.8	0.3	1.5	1.2	0.4	0.3	-0.5	-0.3	0.2	-0.0	0.0	-0.1	0.1	-0.5	0.8
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.4	-0.6	0.0	-0.3	-0.6	-0.1	0.8	1.1	0.8	-0.1	0.6	1.5	0.5	0.5	0.8	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	1.8	-0.6	-0.9	-1.1	-0.4	0.3	0.2	0.4	0.5	-0.0	0.6	1.3	0.1	0.4	0.9	0.3
Medication: Blood pressure	0.4	0.8	2.9	-1.7	-1.1	-0.7	-1.6	0.6	0.2	1.0	0.6	0.5	0.7	1.0	-0.4	0.3	0.5	-0.4
Alcohol drinker status: Never	0.4	0.5	1.9	-1.4	-0.4	-1.2	-1.2	0.1	-0.0	0.6	0.1	0.5	0.5	0.7	-0.3	0.4	0.5	-0.0
Arm predicted mass (left)	0.4	1.9	4.2	-1.6	-1.8	-2.0	-1.5	1.9	0.7	1.4	0.9	1.0	1.5	1.5	0.6	1.0	0.3	1.6
Alzheimer’s Disease (in mother)	0.3	0.4	1.1	-1.0	-0.8	-0.9	-1.1	-0.4	0.4	0.4	0.8	-0.4	-0.0	-0.2	0.5	-0.1	0.1	-0.7
Reaction Time	0.3	0.6	1.8	0.7	1.2	0.2	0.5	-0.9	-0.1	-0.7	-0.8	-0.7	-0.5	-0.5	-0.8	-0.6	-0.5	-1.4
Bipolar Disorder (2011)	0.3	0.3	1.7	0.6	0.7	0.4	1.3	0.6	-0.0	0.1	-0.5	0.4	0.4	0.5	-0.0	0.7	0.3	0.7
Coronary Artery Disease (CAD)	0.3	0.4	1.7	0.7	-0.1	-0.3	1.3	0.6	-0.1	0.1	-0.1	1.2	0.3	0.2	-0.4	0.7	-0.2	1.0
LDL Cholesterol	0.3	0.5	1.5	0.4	0.6	1.2	0.6	-0.4	-0.1	-0.6	-0.5	-0.4	-0.5	-0.1	-1.0	-0.7	-1.2	-0.7
Neuroticism (2016)	0.3	0.4	1.7	0.1	0.6	0.4	0.2	-0.1	-1.3	-0.4	-1.0	-0.4	-0.2	0.3	-1.3	-0.1	0.0	-0.4
Smoking Status	0.3	0.6	2.5	0.1	0.1	-1.6	0.6	0.4	-0.1	0.3	-0.3	1.2	0.7	1.4	0.0	1.0	0.9	0.9
Medication for hormone replacement therapy	0.3	0.3	1.4	0.6	0.2	-0.1	0.8	-0.3	-1.2	-0.8	-0.9	-0.5	-0.5	-0.7	-0.2	-0.2	0.1	0.3
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.1	0.6	0.3	0.5	0.9	0.7	0.4	0.3	0.0	0.3	0.4	0.7	0.1	0.5	0.2	1.1
Medication: Levothyroxine sodium	0.3	0.6	2.8	-0.2	-0.6	-1.7	-0.6	-1.1	-1.0	-0.4	-0.4	-1.2	-0.7	-0.4	-0.4	-0.6	-0.2	-0.0
Past tobacco smoking	0.3	0.5	1.3	0.6	0.6	1.1	0.3	-0.4	0.0	-0.5	-0.4	-0.6	-0.6	-1.1	-0.9	-0.5	-1.1	-0.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.9	-1.1	-0.7	-1.4	-0.5	0.2	0.4	0.4	0.5	0.2	0.5	0.4	0.5	0.5	0.8	-0.1
Heart attack	0.3	0.4	1.1	-0.8	-0.9	0.4	-1.1	0.5	0.0	0.5	0.4	-0.9	-0.1	0.2	-0.6	-0.6	-0.7	0.3
Allergy	0.3	0.6	2.1	1.5	0.9	0.7	1.2	0.1	-1.0	-1.0	-1.2	-0.5	-0.5	-0.6	-0.4	-0.1	-0.5	0.3
Diabetes (self-reported)	0.3	0.4	1.6	-0.7	-0.4	-0.0	-1.3	-0.4	-0.4	-0.5	-0.2	-0.7	-0.7	0.3	-1.1	-0.9	-0.3	-0.1
Hip circumference	0.3	1.2	7.7	0.1	0.4	2.8	0.4	0.4	-0.5	-0.4	-1.1	-0.9	-0.4	0.5	-1.8	-0.8	-1.8	0.1
Worrier / anxious feelings	0.3	0.5	1.6	0.1	0.6	-1.1	-0.2	-0.2	-1.2	-0.4	-1.0	-0.3	-0.4	-1.3	-0.9	-0.2	0.4	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.8	-1.2	-1.2	-0.8	-1.4	0.1	-0.3	0.7	0.2	-0.4	0.3	0.3	-0.4	0.1	0.2	0.0
Impedance of arm (left)	0.3	1.3	4.7	0.1	0.1	-2.2	0.1	-0.1	1.2	1.0	1.0	1.0	1.0	0.9	1.5	1.5	2.0	0.6
Breastfed as a baby	0.3	0.4	1.5	0.3	-0.2	0.5	-0.4	-1.2	-1.0	-0.5	-0.3	-0.8	-0.9	0.1	-0.4	-1.1	-0.4	-0.5
Tense / ‘highly strung’	0.3	0.4	2.6	-0.0	0.5	-1.6	-0.4	-0.4	-0.8	-0.3	-0.7	0.0	-0.0	-1.0	0.1	0.3	0.8	0.2
Pulse wave reflection index	0.3	0.4	2.1	0.6	1.0	0.4	1.4	0.2	-0.2	-0.3	-0.7	0.3	-0.1	0.4	-0.4	0.1	-0.3	0.8
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.8	0.2	-0.1	-1.0	0.0	-0.8	0.5	-0.1	0.5	-0.9	-0.1	0.6	0.8	-0.2	0.3	-1.3
Age at first live birth	0.3	0.5	1.2	-0.4	-0.6	-0.4	-0.7	0.4	0.5	0.7	0.4	0.7	0.8	-0.2	0.6	0.9	1.0	1.1
Medication: Omeprazole	0.3	0.3	1.0	-0.6	-0.4	-0.4	-0.8	-0.5	-1.0	-0.1	-0.3	-0.9	-0.6	-0.2	-0.6	-0.8	-0.2	-0.3
Pulse rate, automated reading	0.3	1.0	2.4	-0.3	-0.2	1.4	-1.2	-0.8	-1.2	-0.5	-0.6	-1.0	-1.1	-0.7	-1.5	-1.3	-1.0	-1.1
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.4	-0.0	-0.2	-0.9	0.5	0.3	0.7	0.5	0.5	0.3	0.5	1.1	1.2	0.5	0.5	0.3
Hypertension (Self-reported)	0.3	0.8	1.7	-0.8	-0.6	1.3	-0.3	-0.5	-0.9	-0.3	-0.1	-1.3	-0.9	0.1	-0.8	-1.3	-1.1	-1.3
Qualifications: nursing, teaching	0.3	0.5	1.7	-0.4	-0.1	0.4	0.6	1.3	0.4	0.4	0.1	0.3	0.7	0.6	0.5	1.0	0.7	1.3
Asthma (self-reported)	0.3	0.7	1.6	0.2	0.2	1.1	0.3	-0.7	-0.3	-0.7	-0.2	0.0	-0.8	-1.1	-1.2	-0.9	-1.3	-1.2
Illnesses of father: None of the above (group 1)	0.3	0.4	1.0	0.7	0.3	-0.9	0.7	-0.4	1.0	0.4	0.6	0.1	0.4	0.9	0.9	0.3	-0.0	-0.4
Miserableness	0.3	0.4	1.6	0.2	-0.0	0.8	0.1	-0.6	-1.3	-0.7	-0.9	-0.4	-0.5	-0.2	-1.2	-0.5	-0.3	-0.6
Ever taken oral contraceptive pill	0.3	0.4	1.7	1.1	0.5	-0.0	1.3	0.7	-0.2	0.1	-0.3	0.2	0.4	0.1	0.2	0.8	0.4	0.8
Hearing aid user	0.3	0.3	2.0	-0.6	-0.7	-0.6	-0.4	-0.5	0.4	0.1	0.7	-0.5	-0.3	1.4	0.0	-0.6	-0.5	-0.1
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.0	-0.2	0.0	0.4	-0.2	-0.6	-0.6	-0.5	-0.5	-0.5	-0.6	-0.4	-0.9	-0.9	-0.9	-1.0
Medication: Lisinopril	0.3	0.3	1.0	0.1	0.5	-0.1	0.7	-0.5	-0.9	-0.4	-1.0	-0.4	-0.3	0.5	-1.0	-0.3	-0.5	-0.3
Ever smoked	0.3	0.6	2.0	-0.7	-0.9	-1.1	-0.7	-0.0	0.5	0.7	0.9	0.4	0.6	0.7	1.4	0.5	1.2	0.1
Irritability	0.3	0.5	2.0	-1.3	-1.0	-0.2	-1.4	-0.1	-0.7	0.2	0.3	-0.4	-0.2	-0.9	-0.2	-0.5	0.5	0.1
Ever had prostate specific antigen (PSA) test	0.3	0.4	0.8	0.3	0.2	0.6	0.6	0.5	0.6	0.4	0.5	0.3	0.5	0.8	0.9	0.7	0.6	0.9
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.6	0.3	0.2	-1.6	-0.2	0.6	0.8	0.5	0.3	1.4	1.0	0.0	0.9	1.3	1.5	0.8
Cholesterol lowering medication	0.3	0.4	1.1	-0.5	-0.5	-1.0	-1.0	-1.0	0.4	-0.0	0.4	-0.7	-0.3	0.7	0.1	-0.6	-0.2	-0.7
Pain experienced in last month	0.3	0.5	1.5	1.2	1.1	0.3	1.2	-1.2	-0.7	-0.6	-0.6	0.1	-0.5	-0.4	-0.5	-0.1	-0.2	-0.8
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.3	-0.8	-1.0	0.3	-1.1	0.4	-0.1	0.4	0.3	-1.0	-0.2	0.3	-0.7	-0.6	-0.8	0.2
Impedance of whole body	0.3	1.4	5.7	0.8	0.9	-2.4	0.9	-0.3	1.6	0.8	1.0	1.1	0.8	0.6	1.6	1.3	1.4	0.0
Body Mass Index (BMI) (2010)	0.2	0.2	0.9	0.1	0.0	0.9	0.7	0.9	0.1	0.2	0.2	0.3	0.3	0.6	0.3	0.4	0.1	0.6
Crohns Disease (2012)	0.2	0.3	0.7	0.2	-0.0	0.8	0.2	-0.4	-0.8	-0.7	-0.7	-0.5	-0.5	-0.1	-0.8	-0.5	-0.6	0.0
Lupus	0.2	0.3	1.2	0.2	-0.3	0.6	0.2	0.2	1.1	0.4	1.0	0.5	0.2	0.1	1.0	0.4	0.6	0.2
Primary Biliary Cirrhosis	0.2	0.3	1.4	-0.6	0.0	-0.5	0.5	1.2	0.2	0.4	0.1	0.1	0.4	0.7	0.5	0.5	0.4	0.7
Blood Eosinophil Count	0.2	1.8	8.0	-1.3	-0.3	-0.8	-0.6	2.2	1.0	1.5	0.7	1.0	1.3	1.3	0.9	1.1	0.6	2.8
Blood Platelet Count	0.2	2.0	9.1	-0.9	-0.6	3.0	-0.7	1.6	1.9	1.3	1.4	1.6	1.1	0.7	1.7	1.0	1.0	1.0
Systolic Blood Pressure	0.2	1.0	2.6	0.8	0.4	1.1	0.0	-0.9	-1.6	-1.0	-1.0	-0.7	-1.1	-0.8	-1.6	-1.0	-0.7	-0.9
Cardiovascular Disease	0.2	0.8	1.9	-0.1	-0.0	0.8	0.1	-0.8	-1.0	-0.9	-0.7	-1.4	-1.2	-0.8	-0.9	-1.3	-1.2	-0.8
Respiratory disease	0.2	0.5	2.6	0.4	0.3	1.6	0.9	-0.0	0.2	-0.4	-0.0	1.0	-0.2	-0.8	-0.8	-0.2	-1.2	-0.0
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.0	-0.5	0.2	0.8	-0.4	-0.3	-0.2	-0.7	-0.4	-0.5	-0.8	0.1	-1.0	-0.9	-0.7	-0.5
Tanning	0.2	2.6	5.8	1.4	2.0	0.1	1.2	-2.0	-1.2	-1.7	-1.5	-1.4	-1.8	-1.0	-1.6	-1.8	-1.9	-2.4
Average weekly spirits intake	0.2	0.2	0.9	-0.1	0.1	-0.6	-0.5	0.2	0.9	0.5	0.4	0.0	0.2	0.5	-0.3	-0.2	-0.6	-0.5
Ever had hysterectomy (womb removed)	0.2	0.2	1.0	-0.5	-0.1	-1.0	-0.3	0.2	-0.3	0.0	-0.0	-0.8	-0.2	0.4	0.0	-0.3	0.2	0.1
Systolic blood pressure, automated reading	0.2	0.6	2.8	1.0	0.6	1.7	0.5	-0.7	-0.1	-0.4	0.0	-0.6	-0.7	-0.4	-0.4	-0.9	-1.2	-1.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.6	-0.7	0.0	-0.3	-0.5	0.1	-0.7	0.0	-0.2	-1.3	-0.4	-0.1	0.5	-0.5	0.2	0.0
Qualifications: CSEs or equivalent	0.2	0.3	1.2	-0.4	-0.4	0.3	0.1	1.1	-0.9	-0.4	-0.5	0.2	-0.2	-0.8	-0.6	-0.0	-0.3	0.5
High blood pressure	0.2	0.6	2.1	-0.4	-0.4	1.4	-0.1	-0.5	-0.7	-0.4	-0.1	-1.1	-0.9	-0.1	-0.7	-1.2	-1.2	-1.0
Stomach or abdominal pain in last month	0.2	0.3	1.9	0.2	0.1	1.4	0.2	0.7	-0.2	0.3	-0.5	0.5	0.3	-0.4	-0.2	0.6	0.1	0.7
Chronic bronchitis/emphysema (father)	0.2	0.2	1.1	0.5	1.0	0.7	0.6	-0.1	0.2	-0.3	-0.3	0.5	0.0	0.1	-0.5	-0.0	-0.5	-0.4
Trunk fat mass	0.2	1.1	4.2	0.3	0.5	2.1	1.1	0.9	-0.3	-0.2	-1.1	-0.8	-0.3	0.5	-1.4	-0.6	-1.9	1.0
Waist circumference	0.2	0.7	4.0	-0.5	-0.2	2.0	0.1	0.9	-0.3	0.0	-0.6	-0.3	-0.1	0.5	-1.3	-0.5	-1.6	0.6
Number of incorrect matches in round	0.2	0.4	1.3	0.7	0.1	0.1	0.9	0.1	1.1	0.3	0.8	0.6	0.5	0.9	0.7	0.5	0.4	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.1	-0.9	-0.3	-1.0	-1.1	-0.3	-0.4	0.1	-0.0	-0.5	-0.1	-0.0	-0.3	-0.0	0.3	-0.4
Had menopause	0.2	0.2	0.9	0.3	0.3	1.0	0.8	-0.3	0.7	-0.1	0.5	0.2	-0.0	0.8	0.4	-0.2	-0.1	0.2
Financial difficulties in last 2 years	0.2	0.3	1.4	-0.9	-1.2	-0.1	-0.6	0.7	0.2	0.1	0.6	0.5	0.1	-0.1	0.0	0.1	0.1	0.4
Pain all over the body in last month	0.2	0.2	1.0	-0.6	-0.3	-0.0	-0.4	-0.0	-0.7	-0.2	-0.6	-1.0	-0.4	-0.4	0.1	-0.5	0.1	0.7
Weight	0.2	0.7	2.9	-1.0	-0.8	0.3	-0.3	1.7	0.3	0.7	-0.0	0.3	0.8	1.2	-0.4	0.4	-0.8	1.7
Alcohol intake versus 10 years previously	0.2	0.3	1.3	0.4	0.2	0.8	-0.1	-0.2	-0.2	-0.2	-0.6	1.1	0.1	-0.4	-1.1	-0.2	-0.5	-0.2
Father’s age at death	0.2	0.2	1.1	-0.2	-0.1	0.3	-0.2	-0.5	0.2	0.0	0.2	0.3	0.2	0.7	-0.0	0.3	1.0	-1.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.1	0.2	0.2	-0.1	0.9	0.4	0.5	0.5	0.5	1.0	0.4	0.4	0.5	0.6	0.0	0.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.7	-0.3	0.2	1.3	0.2	0.1	-0.3	-0.5	-0.1	-1.2	-0.5	0.2	0.2	-0.3	0.3	-0.4
Number of children fathered	0.2	0.2	0.4	0.4	0.4	0.3	0.5	-0.5	0.7	-0.5	0.2	-0.5	-0.5	0.4	0.2	-0.6	-0.5	-0.1
Health satisfaction	0.2	0.2	1.1	-1.0	-0.3	0.1	-1.0	0.4	-0.0	0.1	0.1	-0.5	-0.2	-0.3	-0.2	-0.5	-0.5	-0.1
Neck or shoulder pain in last month	0.2	0.3	1.5	-0.6	-0.9	-0.1	-1.2	0.6	0.1	0.2	0.1	0.3	0.2	-0.3	-0.6	-0.2	-0.3	-0.0
Migraine (self-reported)	0.2	0.2	0.7	0.4	0.6	-0.8	0.6	0.1	-0.0	-0.7	-0.5	-0.2	-0.3	-0.8	0.2	-0.2	-0.3	0.2
Illnesses of father: Heart disease	0.2	0.3	0.9	-0.1	0.4	0.2	-0.2	0.4	-0.6	-0.4	-0.7	-0.3	-0.5	-0.9	-0.5	-0.5	-0.7	0.9
Mood swings	0.2	0.3	0.9	-1.0	-0.8	0.2	-1.0	-0.0	-0.8	0.0	-0.3	-0.4	0.0	0.3	-0.5	-0.1	0.6	-0.0
Ever had bowel cancer screening	0.2	0.2	1.0	-0.1	0.1	0.3	0.3	0.2	1.0	0.3	0.7	0.4	0.4	0.8	0.6	0.5	0.3	-0.3
Diabetes diagnosed by doctor	0.2	0.3	0.9	-0.2	0.2	0.6	-0.4	-0.3	-0.0	-0.6	-0.2	-0.8	-0.7	0.9	-0.7	-0.8	-0.5	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	1.8	-0.2	-0.2	-0.2	-0.5	0.0	-0.2	0.4	0.3	0.4	0.5	0.3	0.5	0.8	1.3	0.4
Friendships satisfaction	0.2	0.2	0.8	0.5	0.8	-0.4	0.9	-0.6	0.1	-0.2	-0.2	-0.2	0.0	0.5	0.1	-0.0	0.1	-0.7
Breast cancer (self-reported)	0.2	0.3	1.1	-0.3	-0.6	1.1	0.1	0.4	0.4	0.3	0.9	0.0	-0.0	0.0	1.0	-0.0	0.1	0.6
Osteoporosis (self-reported)	0.2	0.2	0.7	-0.4	-0.0	-0.8	-0.5	-0.5	0.7	0.1	0.6	-0.3	-0.1	0.3	0.8	0.0	0.4	-0.2
Wears glasses or contact lenses	0.2	0.2	0.7	-0.1	-0.3	0.9	-0.2	-0.7	-0.6	-0.4	-0.2	-0.4	-0.6	-0.1	-0.2	-0.8	-0.5	-0.1
Commuting to job workplace: Public transport	0.2	0.2	0.9	0.0	-0.0	1.0	-0.3	0.5	0.1	0.1	0.1	0.4	0.2	-0.6	0.2	0.2	0.1	1.0
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.9	0.0	0.5	0.7	0.1	0.9	0.3	0.2	-0.3	0.8	0.3	-0.6	-0.6	0.2	-0.4	0.2
Commuting to job workplace: Cycle	0.2	0.2	0.6	0.3	0.4	-0.8	-0.0	-0.5	-0.5	-0.3	-0.3	-0.0	-0.3	-0.4	-0.4	-0.3	-0.3	-0.8
Bipolar Disorder (2018)	0.1	0.2	1.0	-0.4	-0.0	-0.9	0.0	0.3	0.2	0.5	0.3	0.4	0.5	-0.2	0.6	0.6	1.0	0.1
Depressed Affect (Nagel 2018)	0.1	0.3	1.5	-0.1	-0.2	0.0	-0.0	-0.5	-1.2	-0.5	-0.6	-0.9	-0.6	0.3	-0.5	-0.5	-0.2	0.2
Depression (Nagel 2018)	0.1	0.2	1.0	-0.1	-0.1	-0.1	-0.3	-0.3	-1.0	-0.2	-0.6	-1.0	-0.3	0.3	-0.4	-0.1	0.4	0.2
Crohns Disease (2017)	0.1	0.3	1.2	0.2	0.1	0.7	0.7	0.6	0.5	0.4	0.1	0.7	0.7	0.6	0.1	0.7	0.1	1.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.5	-0.2	0.1	-0.7	-0.5	-0.0	-0.4	0.0	-0.2	-0.4	-0.2	0.2	-0.4	-0.3	-0.3	0.0
Townsend deprivation index at recruitment	0.1	0.2	0.5	-0.6	-0.5	-0.2	-0.7	0.3	0.3	0.5	0.3	0.2	0.6	0.6	0.1	0.5	0.6	-0.0
Current tobacco smoking	0.1	0.1	0.5	0.2	0.3	-0.5	0.5	0.0	0.4	0.0	-0.0	0.0	0.2	0.7	-0.0	0.1	-0.2	0.1
Serious illness, injury or assault to yourself	0.1	0.2	0.7	-0.4	-0.2	-0.1	-0.7	0.2	0.8	0.5	0.7	0.1	0.0	0.0	0.1	-0.3	-0.6	-0.0
Qualifications: None of the above	0.1	0.3	1.1	0.2	0.4	0.6	0.0	-0.4	0.5	-0.5	-0.2	-0.5	-0.4	-0.6	-0.6	-0.7	-1.0	-0.3
Mouth/teeth dental problems	0.1	0.2	1.4	0.5	0.6	-1.2	0.3	-0.2	0.1	0.2	-0.1	0.6	0.2	-0.6	0.1	0.2	-0.3	-0.0
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.1	0.3	0.1	1.0	0.8	0.3	0.1	-0.1	0.1	-0.5	-0.4	-0.3	0.5	-0.3	-0.4	0.8
Medication: Cholesterol lowering	0.1	0.2	0.6	-0.1	-0.1	0.5	0.1	0.1	-0.1	-0.4	-0.0	-0.5	-0.5	0.1	-0.5	-0.6	-0.8	-0.2
Headache pain in last month	0.1	0.1	0.4	0.7	0.1	0.3	0.5	0.5	0.4	-0.1	-0.1	0.2	0.1	-0.2	0.3	0.2	-0.3	0.6
Medication: Amlodipine	0.1	0.2	0.6	0.3	0.5	0.5	0.7	0.3	0.6	0.1	0.2	0.4	0.1	0.7	0.1	0.1	-0.3	-0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.1	0.0	0.1	1.0	0.2	0.2	-0.3	-0.3	-0.3	-0.4	-0.3	-0.5	-0.3	-0.2	-0.1	-0.7
Exposure to tobacco smoke outside home	0.1	0.2	0.7	-0.6	-0.7	-0.0	-0.7	0.1	0.5	0.7	0.8	0.2	0.3	0.2	0.3	0.0	0.1	0.0
Number of full brothers	0.1	0.1	0.4	0.2	0.4	0.3	0.5	0.1	-0.6	-0.2	-0.3	-0.1	-0.1	0.0	-0.2	-0.0	0.4	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	-0.4	0.5	0.2	0.2	0.1	-0.6	0.3	-0.5	0.5	0.4	0.3	-0.3	0.5	0.5	0.1
Qualifications: College or University degree	0.1	0.2	1.0	0.3	0.1	-0.4	-0.5	-1.0	-0.2	0.1	0.3	-0.2	-0.3	-0.5	0.8	-0.2	0.4	-0.5
Age at last live birth	0.1	0.2	1.1	-0.0	-0.1	-0.6	-0.5	0.4	-0.5	-0.1	-0.3	-0.1	-0.0	-0.9	0.3	0.1	0.3	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	0.7	0.3	0.2	0.4	0.8	0.1	-0.2	-0.4	-0.0	0.1	-0.6	-0.3	-0.2	-0.6	-0.7	-0.1
Back pain experienced in last month	0.1	0.1	0.7	0.0	0.6	-0.3	-0.3	-0.0	0.8	0.2	0.3	0.4	0.3	-0.1	0.2	0.1	-0.1	-0.4
Smoking status: Current	0.1	0.2	0.6	0.2	0.2	-0.6	0.4	0.0	0.6	0.2	0.1	0.5	0.4	0.8	0.1	0.5	0.0	0.2
Financial situation satisfaction	0.1	0.1	0.4	-0.4	-0.5	-0.4	0.1	0.1	0.0	-0.4	0.1	-0.3	-0.3	0.4	-0.2	-0.3	-0.6	-0.3
High cholesterol (Self-reported)	0.1	0.1	0.3	0.4	-0.0	0.3	0.5	0.1	0.4	-0.3	-0.0	-0.4	-0.1	0.6	0.2	-0.1	-0.4	0.4
Medication: Bendroflumethiazide	0.1	0.2	0.5	-0.6	0.1	-0.7	0.5	0.7	-0.2	0.2	-0.3	0.5	0.2	0.7	-0.6	0.4	0.2	0.4
Age started oral contraceptive pill	0.1	0.2	0.6	0.3	-0.0	-0.4	-0.5	-0.8	0.4	0.2	0.3	-0.7	-0.0	-0.2	0.6	-0.1	0.4	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.4	0.0	0.2	0.2	-0.3	-0.4	-0.5	-0.3	-0.3	0.1	-0.3	-0.5	-0.6	-0.4	-0.5	-0.5
Ovarian Cancer	0.0	0.1	0.4	0.1	-0.2	0.1	0.0	0.2	-0.2	-0.1	-0.3	-0.3	-0.1	-0.3	-0.0	-0.2	-0.2	0.7
Hair Pigment	0.0	1.3	3.9	-1.9	-2.0	-0.3	-1.1	1.3	0.3	1.1	1.0	0.2	0.9	1.2	0.5	0.9	1.3	1.0
Fluid intelligence score	0.0	0.0	0.2	0.2	0.5	0.2	0.0	-0.1	-0.2	-0.1	-0.3	0.1	-0.1	-0.5	0.1	0.1	0.1	-0.1
Length of working week for main job	0.0	0.0	0.2	-0.2	0.2	-0.2	-0.3	-0.1	-0.4	-0.2	-0.2	0.1	-0.3	-0.0	-0.1	-0.1	0.3	-0.1

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