Best TWAS P=1.68e-10 · Best GWAS P=1.14e-08 conditioned to 0.00858
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AC006547.14 | 0.09 | 0.00 | lasso | 4 | 0.00 | 6.9e-01 | 4.8 | -6.4 | 1.7e-10 | 0.55 | 0.04 | 0.33 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | ZDHHC8 | 0.18 | 0.07 | enet | 26 | 0.14 | 8.9e-11 | -5.0 | -5.3 | 1.2e-07 | 0.32 | 0.09 | 0.91 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ARVCF | 0.04 | 0.00 | blup | 116 | 0.00 | 1.8e-01 | 4.8 | -5.6 | 2.0e-08 | 0.53 | 0.03 | 0.14 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARVCF | 0.03 | 0.01 | blup | 116 | 0.01 | 1.1e-02 | -2.8 | -5.4 | 6.2e-08 | 0.58 | 0.02 | 0.45 | FALSE |