Best TWAS P=1.11e-14 · Best GWAS P=1.66e-16 conditioned to 2.55e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MRPS9 | 0.20 | 0.18 | bslmm | 519 | 0.20 | 3.3e-23 | -4.3 | 5.3 | 9.0e-08 | 0.18 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Artery Tibial | MRPS9 | 0.17 | 0.10 | enet | 31 | 0.11 | 7.1e-09 | -4.1 | 5.5 | 3.1e-08 | 0.21 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Brain Caudate basal ganglia | MRPS9 | 0.24 | 0.01 | lasso | 6 | 0.00 | 3.6e-01 | -4.1 | 5.4 | 6.9e-08 | 0.18 | 0.08 | 0.22 | FALSE |
| 4 | GTEx | Brain Caudate basal ganglia | AC104655.2 | 0.25 | 0.00 | lasso | 9 | 0.02 | 8.5e-02 | 3.0 | 7.7 | 1.1e-14 | 0.65 | 0.06 | 0.60 | TRUE |
| 5 | GTEx | Brain Hippocampus | AC104655.2 | 0.23 | 0.04 | lasso | 7 | 0.06 | 1.9e-02 | 5.3 | 5.9 | 3.6e-09 | 0.44 | 0.11 | 0.16 | FALSE |
| 6 | GTEx | Esophagus Muscularis | MRPS9 | 0.18 | 0.09 | lasso | 5 | 0.08 | 1.4e-05 | -4.1 | 5.3 | 1.3e-07 | 0.13 | 0.99 | 0.00 | FALSE |
| 7 | GTEx | Skin Not Sun Exposed Suprapubic | AC104655.2 | 0.15 | 0.09 | enet | 12 | 0.05 | 6.5e-04 | -4.1 | 5.2 | 2.7e-07 | 0.24 | 0.81 | 0.08 | FALSE |