[Hub]/) : Traits : BMI : ← →

chr2:99,468,341-101,731,705

Best TWAS P=1.81e-18 · Best GWAS P=7.06e-19 conditioned to 0.0653

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AFF3 0.31 0.24 enet 32 0.25 9.2e-31 -5.6 -5.4 7.3e-08 -0.17 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex CHST10 0.05 0.02 blup 474 0.04 1.0e-05 5.9 -6.0 2.7e-09 -0.68 0.78 0.19 FALSE
3 GTEx Adrenal Gland CHST10 0.18 0.04 lasso 4 0.05 5.6e-03 -6.3 5.8 9.0e-09 0.48 0.35 0.09 FALSE
4 GTEx Artery Aorta AFF3 0.14 0.06 lasso 5 0.07 1.2e-04 -8.4 -8.8 1.8e-18 -0.43 0.06 0.93 TRUE
5 GTEx Artery Tibial AFF3 0.06 0.04 enet 6 0.04 4.3e-04 2.9 -5.3 1.4e-07 -0.20 0.47 0.36 FALSE
6 GTEx Cells EBV-transformed lymphocytes CHST10 0.25 0.15 lasso 4 0.12 9.1e-05 5.8 -5.1 2.9e-07 -0.54 0.36 0.09 TRUE
7 GTEx Muscle Skeletal LONRF2 0.07 0.08 lasso 4 0.08 2.5e-08 -6.2 -6.2 4.5e-10 -0.58 1.00 0.00 FALSE
8 GTEx Skin Sun Exposed Lower leg LONRF2 0.05 0.03 lasso 2 0.02 9.3e-03 6.3 -7.3 2.7e-13 -0.74 0.03 0.91 FALSE
9 GTEx Thyroid CHST10 0.05 0.05 lasso 5 0.03 2.6e-03 -6.3 -7.5 7.2e-14 -0.75 0.45 0.31 TRUE
10 ROSMAP Brain Pre-frontal Cortex AFF3 0.31 0.24 enet 38 0.25 3.5e-32 -5.7 -5.8 5.1e-09 -0.25 1.00 0.00 FALSE
11 ROSMAP Brain Pre-frontal Cortex AC092667.2 0.16 0.03 blup 439 0.10 2.2e-12 5.0 -5.6 2.1e-08 -0.36 0.99 0.00 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LONRF2 0.06 0.04 blup 69 0.04 3.4e-05 6.1 -7.7 1.8e-14 -0.72 0.70 0.27 FALSE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LONRF2 0.05 0.08 lasso 2 0.08 2.9e-05 6.0 -5.8 5.0e-09 -0.61 0.23 0.08 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma CHST10 0.04 0.04 lasso 3 0.03 2.6e-04 -6.0 -6.0 1.7e-09 -0.59 0.47 0.24 FALSE