[Hub]/) : Traits : BMI :

chr3:8,322,531-10,443,090

Best TWAS P=1.02e-08 · Best GWAS P=1.7e-09 conditioned to 5.36e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SETD5-AS1 0.18 0.17 lasso 9 0.15 3.3e-12 5.4 -5.3 1.2e-07 -0.49 0.08 0.92 FALSE
2 GTEx Adipose Subcutaneous RP11-380O24.1 0.07 0.09 lasso 5 0.08 8.3e-07 5.2 -5.3 1.1e-07 -0.43 0.08 0.92 FALSE
3 GTEx Breast Mammary Tissue SETD5-AS1 0.13 0.11 lasso 2 0.06 4.2e-04 5.2 -5.5 5.0e-08 -0.43 0.08 0.86 FALSE
4 GTEx Breast Mammary Tissue (Female) SETD5-AS1 0.19 0.04 lasso 4 0.03 3.6e-02 5.2 -5.2 2.3e-07 -0.55 0.08 0.46 FALSE
5 GTEx Cells Transformed fibroblasts SETD5-AS1 0.24 0.25 lasso 4 0.25 1.2e-18 5.4 -5.4 5.6e-08 -0.43 0.08 0.92 FALSE
6 GTEx Cells Transformed fibroblasts RP11-380O24.1 0.38 0.32 lasso 6 0.31 5.8e-24 5.4 -5.6 2.2e-08 -0.43 0.08 0.92 FALSE
7 GTEx Esophagus Mucosa RP11-380O24.1 0.24 0.18 lasso 7 0.16 3.5e-11 5.4 -5.4 5.3e-08 -0.41 0.08 0.92 FALSE
8 GTEx Esophagus Muscularis SRGAP3 0.52 0.10 enet 20 0.23 4.1e-14 5.6 5.3 1.4e-07 0.55 0.07 0.93 FALSE
9 GTEx Muscle Skeletal RP11-380O24.1 0.17 0.11 lasso 6 0.12 1.9e-11 5.4 -5.5 3.2e-08 -0.40 0.08 0.92 FALSE
10 GTEx Pancreas SETD5-AS1 0.21 0.09 enet 14 0.14 1.2e-06 5.4 -5.1 3.0e-07 -0.57 0.09 0.91 FALSE
11 GTEx Thyroid THUMPD3 0.24 0.10 lasso 7 0.10 4.6e-08 5.6 -5.5 3.7e-08 -0.38 0.06 0.94 FALSE
12 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LOC440944 0.07 0.02 blup 62 0.03 1.1e-02 5.4 -5.7 1.0e-08 -0.50 0.01 0.65 TRUE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC440944 0.04 0.05 enet 10 0.05 6.0e-06 5.4 -5.2 2.2e-07 -0.44 0.01 0.98 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma CIDECP 0.08 0.03 lasso 1 0.02 7.8e-04 5.5 5.5 3.3e-08 -0.06 0.00 0.92 TRUE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma VHL 0.04 0.00 blup 61 0.02 1.7e-03 1.6 -5.2 1.7e-07 0.05 0.01 0.27 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma VHL 0.03 0.00 blup 61 0.01 8.2e-02 4.3 -5.2 2.7e-07 0.09 0.01 0.29 FALSE