TWAS hub - VHL

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0970	0.0290	6.7e-05	0.055	0.042	0.027	0.054	0.047	2.6e-07	6.0e-06	2.5e-04	3.4e-07	2.1e-06
2	GTEx	Cells Transformed fibroblasts	0.1260	0.0450	1.5e-04	0.035	NA	0.019	NA	0.021	1.2e-03	NA	1.3e-02	NA	9.7e-03
3	GTEx	Esophagus Mucosa	0.1430	0.0550	1.9e-03	-0.002	NA	-0.004	NA	0.001	4.5e-01	NA	7.2e-01	NA	2.9e-01
4	ROSMAP	Brain Pre-frontal Cortex	0.2653	0.0391	1.4e-14	0.195	0.109	0.197	0.183	0.196	2.0e-24	7.3e-14	1.0e-24	5.6e-23	1.2e-24
5	YFS	Blood	0.1479	0.0265	5.6e-17	0.074	0.067	0.079	0.078	0.083	3.3e-23	5.3e-21	1.0e-24	2.2e-24	9.7e-26
6	TCGA	Lung Adenocarcinoma	0.0299	0.0183	9.7e-03	0.022	0.015	0.010	NA	0.013	1.2e-03	6.5e-03	1.9e-02	NA	1.0e-02
7	TCGA	Lung Squamous Cell Carcinoma	0.0404	0.0227	1.7e-03	0.002	0.021	0.011	NA	0.005	1.9e-01	1.7e-03	2.0e-02	NA	7.7e-02
8	TCGA	Prostate Adenocarcinoma	0.0252	0.0156	7.1e-03	0.003	0.005	0.001	NA	0.004	1.6e-01	8.2e-02	2.4e-01	NA	1.2e-01
9	TCGA	Thyroid Carcinoma	0.0440	0.0210	2.5e-04	0.001	0.019	0.020	NA	0.007	2.2e-01	4.9e-03	4.0e-03	NA	6.8e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Ulcerative Colitis	4.5	6.5	12.2	2.1	2.5	3.5	0.1	1.3	2.4	3.3	3.4	2.5
Medication: Aspirin	4.4	5.8	13.0	-2.0	-1.0	-2.9	-0.9	-1.0	-2.2	-3.6	-3.1	-2.9
Ulcerative Colitis (UC)	3.8	7.1	11.8	2.8	1.1	3.1	1.3	2.4	2.6	3.4	3.3	3.0
Long-standing illness, disability or infirmity	3.8	5.8	11.7	-2.2	-0.8	-3.0	-1.2	-1.3	-3.2	-2.1	-3.4	-2.7
Medication: Aspirin	3.3	4.3	10.3	-1.9	-0.9	-2.5	-0.8	-1.0	-1.8	-3.2	-2.6	-2.4
Number of operations (self-reported)	3.3	5.0	8.8	-2.6	-0.1	-1.8	-1.8	-1.9	-2.8	-2.2	-3.0	-2.5
Waist circumference	3.0	10.8	22.8	-2.6	-0.7	-3.5	-2.1	-2.5	-3.9	-3.7	-4.8	-4.0
Weight	3.0	14.8	32.1	-2.1	-2.7	-5.2	-0.8	-1.8	-4.3	-4.8	-5.7	-4.1
Alcohol intake versus 10 years previously	3.0	4.5	11.0	-2.0	-1.7	-2.2	-0.6	-1.6	-1.9	-3.3	-2.6	-2.1
Arm fat mass (left)	3.0	12.5	26.8	-2.4	-1.3	-3.8	-1.7	-2.3	-3.8	-4.7	-5.2	-4.3
Alcohol drinker status: Never	3.0	3.5	7.1	-1.6	-1.4	-2.0	-0.6	-0.8	-1.9	-2.5	-2.7	-2.4
Hip circumference	2.9	12.4	27.7	-1.8	-2.3	-4.7	-0.7	-1.6	-4.1	-4.3	-5.3	-3.9
Leg fat mass (left)	2.9	11.2	25.2	-2.1	-1.6	-3.8	-1.4	-2.1	-3.5	-4.3	-5.0	-4.0
Body mass index (BMI)	2.8	11.8	24.6	-2.5	-1.2	-3.6	-1.8	-2.4	-3.4	-4.8	-5.0	-4.2
Worry too long after embarrassment	2.7	4.6	10.4	1.6	1.9	2.4	0.2	0.9	2.2	3.2	2.8	2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.7	3.2	9.9	0.3	2.9	3.1	-1.5	-0.9	0.5	2.0	1.6	0.8
Pain type(s) experienced in last month: Hip pain	2.7	3.3	6.8	-2.2	0.6	-1.2	-1.9	-2.0	-2.0	-0.9	-2.0	-2.6
Arm fat mass (right)	2.6	10.8	24.0	-2.0	-1.2	-3.5	-1.6	-2.2	-3.6	-4.4	-4.9	-4.0
Leg fat mass (right)	2.6	10.0	22.9	-1.9	-1.4	-3.6	-1.5	-2.1	-3.4	-4.0	-4.8	-3.8
Trunk fat mass	2.5	10.7	23.9	-2.0	-1.4	-3.9	-1.4	-2.0	-3.7	-4.1	-4.9	-3.8
Neck or shoulder pain in last month	2.5	3.5	7.9	-0.9	0.0	-1.5	-1.6	-1.6	-2.5	-1.7	-2.8	-2.6
Heart disease (mother)	2.5	3.1	12.1	0.7	-3.5	-2.0	2.4	0.9	0.7	-1.9	-0.8	-0.0
Whole body fat mass	2.5	10.5	23.4	-2.1	-1.4	-3.8	-1.5	-2.1	-3.6	-4.1	-4.8	-3.8
Commuting to job workplace: Walk	2.5	2.7	4.0	-1.8	-1.2	-2.0	-0.9	-1.7	-2.0	-1.2	-1.9	-1.7
Leg fat-free mass (left)	2.4	12.9	29.0	-1.4	-3.3	-5.4	0.2	-1.0	-3.8	-4.5	-5.2	-3.3
Leg predicted mass (left)	2.4	12.6	28.6	-1.4	-3.3	-5.3	0.2	-1.1	-3.8	-4.5	-5.1	-3.2
Leg fat-free mass (right)	2.4	12.8	30.6	-1.5	-3.6	-5.5	0.4	-0.7	-3.8	-4.4	-5.0	-3.2
Leg predicted mass (right)	2.4	12.9	30.7	-1.5	-3.5	-5.5	0.4	-0.7	-3.9	-4.4	-5.1	-3.2
Arm fat-free mass (left)	2.4	12.0	25.6	-1.2	-3.7	-5.1	0.5	-0.8	-3.7	-4.2	-5.0	-3.1
Arm predicted mass (left)	2.4	12.4	27.4	-1.3	-3.8	-5.2	0.5	-0.8	-3.7	-4.2	-5.0	-3.1
Illnesses of siblings	2.3	3.2	7.3	1.4	2.1	2.7	-0.6	-0.1	1.1	2.4	2.2	1.6
Basal metabolic rate	2.3	12.8	27.9	-1.4	-3.5	-5.3	0.2	-1.0	-3.9	-4.3	-5.2	-3.3
BMI	2.2	12.8	27.4	-2.4	-1.7	-4.1	-1.3	-2.3	-3.5	-5.2	-5.2	-4.1
Impedance of leg (right)	2.2	10.5	22.4	2.4	1.9	3.7	1.1	1.9	3.3	4.7	4.4	3.8
Pain all over the body in last month	2.2	2.4	5.8	-1.2	-0.4	-0.8	-1.3	-1.6	-2.4	-0.8	-2.3	-1.7
Arm fat percentage (left)	2.2	8.8	17.7	-2.4	0.0	-2.3	-2.3	-2.5	-3.2	-3.7	-4.2	-3.9
Bipolar Disorder (2011)	2.1	2.1	4.5	-1.1	1.7	1.9	-2.1	-1.3	-1.0	-0.4	-1.0	-1.6
Medication: Co-codamol	2.1	2.5	7.6	-1.0	-1.6	-2.8	0.1	-0.3	-1.3	-1.7	-2.0	-1.5
Impedance of leg (left)	2.1	10.2	22.7	2.3	1.7	3.6	1.3	2.3	3.2	4.8	4.3	3.6
Time employed in main current job	2.1	2.5	4.6	1.9	0.8	2.1	1.1	1.3	1.9	1.3	1.8	1.3
Arm fat-free mass (right)	2.1	11.0	24.4	-1.3	-3.8	-4.9	0.6	-0.7	-3.5	-4.0	-4.7	-2.9
Arm predicted mass (right)	2.1	10.5	24.2	-1.2	-3.7	-4.9	0.6	-0.7	-3.3	-3.9	-4.5	-2.7
Medication for cholesterol	2.1	3.2	7.3	2.7	0.3	1.1	1.5	1.9	1.6	2.3	1.8	1.7
Whole body water mass	2.1	11.9	27.3	-1.2	-3.7	-5.2	0.6	-0.7	-3.8	-4.1	-4.9	-3.0
Medication: Blood pressure	2.1	4.1	7.9	-2.8	-0.5	-1.8	-1.6	-2.0	-2.2	-2.4	-2.2	-1.7
Whole body fat-free mass	2.0	11.5	26.8	-1.1	-3.8	-5.2	0.7	-0.6	-3.6	-4.0	-4.8	-2.9
Hearing aid user	2.0	2.3	4.3	-1.6	1.4	-0.0	-2.0	-1.7	-2.1	0.0	-1.6	-1.5
Alzheimer’s Disease (in mother)	1.9	2.3	6.0	-1.0	2.1	0.9	-2.4	-2.4	-1.0	1.1	-0.4	-0.5
Financial difficulties in last 2 years	1.9	2.5	4.4	2.1	0.2	1.5	1.4	1.4	1.8	1.4	1.8	2.0
Arm fat percentage (right)	1.9	7.5	15.9	-2.0	-0.1	-2.2	-2.0	-2.2	-2.9	-3.6	-4.0	-3.6
Age started oral contraceptive pill	1.9	2.4	4.5	1.8	-0.0	1.7	1.4	1.3	1.9	1.1	1.7	2.1
Heart disease (siblings)	1.9	2.4	5.6	0.9	-2.2	-1.7	2.2	2.4	1.2	-1.0	-0.1	0.2
Bilateral oophorectomy (both ovaries removed)	1.8	2.0	4.1	-2.0	-1.3	-1.8	-0.5	-0.7	-1.8	-1.1	-1.5	-1.4
Serious illness, injury or assault to yourself	1.8	2.2	6.0	1.1	-2.4	-2.0	1.9	1.2	0.3	-1.6	-0.9	0.0
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	8.6	1.2	1.8	1.2	-0.1	0.7	0.7	2.9	1.6	1.8
Shortness of breath walking on level ground	1.8	2.1	4.8	-1.6	2.2	-0.4	-2.2	-1.2	-1.3	0.5	-1.1	-1.4
Supplements: Vitamin C	1.8	2.1	5.0	0.9	-2.2	-0.8	2.1	0.9	1.6	0.3	1.1	1.8
Knee pain experienced in last month	1.8	2.9	6.8	-0.5	-1.4	-2.6	-0.4	-1.0	-2.3	-0.9	-2.5	-1.7
Illnesses of father: High blood pressure	1.8	2.2	4.8	-1.7	0.5	-0.9	-1.5	-1.4	-2.2	-1.1	-1.6	-1.9
Trunk fat percentage	1.7	6.6	15.0	-1.7	-0.6	-2.8	-1.4	-1.7	-2.8	-3.3	-3.9	-3.1
Medication: Atenolol	1.7	2.2	4.9	-2.0	1.6	0.2	-2.2	-1.8	-1.7	-0.6	-0.8	-1.1
Body fat percentage	1.7	6.8	14.9	-1.9	-0.4	-2.5	-1.8	-2.1	-2.7	-3.3	-3.9	-3.2
Breast cancer (self-reported)	1.7	2.1	4.2	1.5	-0.2	1.6	1.4	0.8	2.0	1.2	1.4	1.9
Pain experienced in last month	1.7	2.8	6.7	0.8	1.0	2.6	0.5	0.5	1.8	2.1	2.2	1.9
Impedance of whole body	1.7	8.6	20.4	1.8	2.4	3.5	0.5	1.6	2.4	4.5	4.0	3.3
Trunk fat-free mass	1.6	9.2	21.1	-0.8	-3.6	-4.6	0.8	-0.4	-3.3	-3.5	-4.2	-2.5
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.3	8.7	1.2	-2.8	-0.8	3.0	1.7	1.6	-0.5	1.0	1.9
Average weekly red wine intake	1.6	2.3	5.8	-1.3	-2.2	-2.4	1.0	0.5	-0.9	-1.8	-1.6	-1.1
Leg fat percentage (left)	1.6	5.8	12.6	-1.7	-0.3	-2.0	-1.8	-2.0	-2.3	-3.2	-3.5	-3.2
Smoking Status	1.5	3.7	6.4	-1.6	-1.8	-2.5	-0.5	-1.6	-2.2	-1.8	-2.5	-1.8
Angina	1.5	2.0	5.8	-0.7	-1.3	-2.4	0.2	0.2	-1.1	-2.1	-1.9	-0.7
Trunk predicted mass	1.5	8.8	19.8	-0.8	-3.5	-4.5	0.8	-0.5	-3.3	-3.3	-4.2	-2.5
Had major operations	1.5	1.8	3.8	-1.4	-0.4	-1.7	-0.6	-0.6	-1.5	-1.4	-1.9	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.7	3.8	-1.3	0.1	-1.2	-1.0	-0.9	-1.6	-2.0	-1.4	-1.4
Mineral and other dietary supplements	1.5	2.0	4.2	-1.6	1.0	-0.5	-1.9	-1.4	-2.1	-0.9	-1.6	-1.1
Vascular/heart problems diagnosed by doctor	1.5	4.0	7.0	2.2	-0.4	1.8	1.8	1.7	2.2	2.6	2.4	1.9
Alzheimer’s Disease (including proxy)	1.4	2.1	4.7	-1.4	1.8	0.9	-2.2	-2.2	-0.9	1.6	-0.1	-0.0
Irritable Bowel Disease (IBD)	1.4	3.4	9.1	1.4	0.8	1.9	0.6	1.5	1.8	3.0	2.5	1.9
Primary Biliary Cirrhosis	1.4	2.0	4.5	1.0	-2.1	-0.0	2.1	1.4	1.4	-0.9	0.8	1.6
Diabetes (mother)	1.4	1.8	3.4	-1.8	0.8	-0.8	-1.3	-1.1	-0.8	-1.7	-1.4	-1.8
Impedance of arm (right)	1.4	6.6	16.4	1.8	2.3	3.0	0.4	1.4	1.9	4.0	3.4	2.9
Leg fat percentage (right)	1.4	5.0	10.6	-1.5	0.0	-1.7	-1.8	-2.0	-2.1	-2.9	-3.3	-2.9
Exposure to tobacco smoke outside home	1.4	1.9	5.2	-1.6	0.0	-0.1	-1.4	-1.4	-1.6	-2.3	-1.3	-1.3
Angina (self-reported)	1.4	1.9	5.8	-0.6	-1.5	-2.4	0.4	0.4	-1.0	-2.0	-1.7	-0.5
Alcohol intake frequency.	1.4	3.2	7.5	-1.5	-1.8	-2.1	-0.4	-0.9	-1.9	-1.6	-2.7	-2.2
Friendships satisfaction	1.4	1.8	5.4	1.0	0.7	1.1	0.4	0.3	0.7	2.3	1.8	1.9
Medication: Metformin	1.3	1.9	6.3	-0.8	-1.4	-1.8	0.5	0.4	-0.3	-2.5	-1.7	-1.3
Comparative height size at age 10	1.3	7.3	18.7	0.4	-3.5	-4.3	1.6	0.9	-2.9	-2.7	-3.5	-1.8
Diabetes diagnosed by doctor	1.3	2.1	4.4	-1.5	-0.6	-2.0	-0.5	-0.4	-1.3	-1.8	-2.1	-1.6
Osteoarthritis (self-reported)	1.3	1.7	3.8	-0.8	-1.2	-1.9	-0.0	-0.5	-1.2	-1.6	-1.9	-1.4
Hearing difficulty/problems: Yes	1.2	1.8	4.7	-1.3	-0.2	-1.3	-0.6	-1.0	-1.7	-1.2	-2.2	-1.4
Heart attack	1.2	1.6	4.0	-1.1	0.5	-1.4	-1.3	-0.8	-2.0	-0.8	-1.4	-1.3
Birth weight	1.2	2.7	6.2	-0.5	-2.0	-2.5	0.9	0.9	-1.4	-2.5	-1.5	-1.1
Age at last live birth	1.2	1.7	2.8	1.2	1.6	1.7	-0.1	0.3	1.2	1.7	1.5	1.3
Smoking status: Previous	1.2	1.8	3.9	-1.2	-1.2	-1.6	-0.5	-1.6	-2.0	-1.3	-1.3	-1.0
Illnesses of father: None of the above (group 1)	1.2	1.5	4.0	2.0	-1.4	-0.2	1.9	1.3	1.2	-0.1	0.2	0.8
Supplements: Calcium	1.2	1.3	2.7	1.6	0.4	1.2	1.1	0.9	1.6	0.7	1.2	1.2
Heart attack/myocardial infarction (self-reported)	1.2	1.6	3.9	-1.1	0.4	-1.5	-1.3	-0.6	-2.0	-0.9	-1.5	-1.4
Schizophrenia (2014)	1.1	2.4	5.8	0.1	1.3	2.4	0.0	-0.0	1.6	1.8	2.3	1.8
Supplements: Zinc	1.1	1.2	2.6	1.2	-1.1	0.2	1.4	0.9	1.1	0.7	0.8	1.6
Alcohol usually taken with meals	1.1	1.7	4.4	1.4	-1.4	-0.5	2.1	1.8	1.3	0.5	0.7	1.0
Impedance of arm (left)	1.1	5.2	13.2	1.2	2.5	2.8	-0.2	0.8	1.4	3.6	3.1	2.5
Qualifications: College or University degree	1.1	3.3	8.8	0.7	1.2	2.4	0.2	0.2	2.0	1.8	3.0	2.6
Medication for pain relief, constipation, heartburn	1.1	1.9	7.8	0.2	1.0	1.4	-0.2	-0.4	0.6	2.8	1.7	1.6
Migraine (self-reported)	1.1	1.3	4.0	-0.3	-1.4	-1.5	0.6	0.4	-0.7	-2.0	-1.5	-0.7
Type 2 Diabetes (T2D) (2018)	1.0	1.9	4.7	-1.6	-0.6	-2.2	-0.7	-0.6	-1.6	-1.1	-1.8	-1.3
Diabetes (father)	1.0	1.2	2.6	0.4	0.3	1.3	0.6	1.0	1.2	1.6	1.5	1.2
High blood pressure	1.0	2.8	4.7	-2.0	0.8	-1.2	-1.8	-1.6	-1.7	-2.2	-1.8	-1.5
Hair/balding pattern: Pattern 3	1.0	1.5	4.0	-1.4	1.3	0.1	-2.0	-2.0	-1.2	0.1	-0.7	-0.6
Headache pain in last month	1.0	1.7	3.8	0.1	-1.9	-1.9	1.7	1.2	0.6	-1.8	-0.4	-0.2
Age at first live birth	1.0	1.8	3.4	1.6	1.3	1.7	0.4	0.8	1.4	1.0	1.8	1.4
Pulse wave peak to peak time	1.0	1.1	2.9	0.3	-1.7	-1.7	1.2	1.0	-0.4	-1.0	-0.7	-0.3
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	3.0	-1.4	1.7	-0.4	-1.7	-1.0	-0.8	-0.1	-0.2	-1.3
Illnesses of siblings: Diabetes	1.0	1.2	3.1	-1.0	0.2	-0.8	-0.8	-0.1	-0.9	-1.4	-1.6	-1.8
Number of self-reported non-cancer illnesses	1.0	1.7	3.2	-1.7	1.0	-1.2	-1.5	-0.9	-1.8	-0.8	-1.4	-0.8
Ovarian Cancer	0.9	1.2	6.8	0.3	0.2	1.0	0.0	-0.3	0.1	2.6	1.1	1.3
Type 2 Diabetes (T2D) (2012)	0.9	1.0	2.4	1.5	0.2	0.8	0.2	-0.2	1.1	1.3	1.3	1.1
Number of treatments/medications taken	0.9	1.7	4.0	-0.5	-1.4	-1.8	0.3	-0.0	-0.9	-2.0	-1.8	-1.2
Pulse wave Arterial Stiffness index	0.9	1.0	2.8	-0.1	1.6	1.7	-1.0	-0.8	0.4	1.2	0.7	0.5
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.1	1.4	-0.5	0.3	1.3	1.0	1.4	0.9	0.7	1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	2.5	-0.1	1.6	1.2	-0.9	-0.8	0.1	1.4	1.1	0.9
Emphysema/chronic bronchitis	0.9	1.0	2.3	-1.1	-0.1	-0.7	-1.0	-0.7	-1.5	-0.7	-1.0	-1.4
Hypertension (Self-reported)	0.9	2.4	3.8	-2.0	0.7	-1.2	-1.5	-1.3	-1.7	-1.9	-1.7	-1.4
Medication: Paracetamol	0.9	1.5	3.2	1.6	-1.4	-0.3	1.8	1.7	1.1	-0.4	0.4	0.9
Risk taking	0.9	1.3	4.3	0.7	-2.1	-0.8	1.3	1.1	0.1	-1.3	-0.9	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	3.0	-1.2	0.0	-1.2	-0.4	-0.1	-0.7	-1.7	-1.1	-1.4
Worry (Nagel 2018)	0.8	1.7	3.7	1.4	-0.1	0.6	0.7	0.9	1.7	1.8	1.5	1.9
Vitamin and mineral supplements	0.8	1.1	2.8	-0.4	0.1	-1.2	-0.4	0.2	-1.3	-1.1	-1.6	-1.7
Taking other prescription medications	0.8	1.3	4.6	-0.2	-0.5	-1.2	-0.3	-0.2	-1.0	-2.1	-1.7	-1.3
Sitting height	0.8	5.6	16.4	1.4	-4.0	-3.9	2.5	1.5	-1.7	-1.2	-2.0	-0.5
Qualifications: A levels/AS levels or equivalent	0.8	1.7	3.2	1.1	1.2	1.8	0.3	0.5	1.8	1.2	1.8	1.2
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.5	-0.4	-1.6	-1.5	0.7	0.1	-0.7	-1.4	-1.2	-0.4
Illnesses of father: Heart disease	0.8	1.1	2.5	-1.6	1.1	0.1	-1.3	-1.0	-0.5	-1.0	-0.4	-1.4
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.4	1.0	-1.3	-0.2	1.5	0.7	1.3	0.7	1.0	0.8
Medication: Atorvastatin	0.8	1.0	3.5	0.6	1.9	1.1	-0.5	0.6	1.1	0.8	1.0	0.7
Ever depressed for a whole week	0.8	1.0	4.9	-0.6	0.5	0.2	-1.5	-2.2	-0.8	-0.4	-0.3	-0.3
HDL Cholesterol	0.7	1.1	3.2	-1.4	1.8	0.5	-1.6	-0.6	-1.0	0.5	-0.1	-0.4
Blood Eosinophil Count	0.7	5.0	12.6	-1.4	3.2	2.2	-2.7	-1.7	-2.2	3.5	0.5	0.5
Average weekly spirits intake	0.7	0.9	2.0	-1.2	0.3	-0.0	-0.8	-0.4	-0.9	-1.1	-1.4	-1.3
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.1	-0.2	-0.9	-1.4	0.8	0.8	0.0	-0.9	-1.1	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	1.9	-0.8	0.3	-1.0	-1.1	-1.2	-1.4	-0.5	-1.1	-0.8
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	3.3	0.6	-0.6	-1.2	0.0	-0.1	-0.2	-1.8	-0.5	-0.9
Mouth/teeth dental problems	0.7	1.1	2.2	0.3	0.8	1.2	0.2	0.6	1.5	1.5	1.4	0.8
Tense / ‘highly strung’	0.7	1.1	3.4	0.9	0.7	1.0	-0.2	0.2	1.2	1.8	1.2	1.2
Loud music exposure frequency	0.7	0.8	3.1	0.8	0.4	1.2	-0.0	0.2	0.5	1.8	0.9	0.8
Health satisfaction	0.7	0.9	1.6	-0.8	1.0	-0.9	-1.2	-1.0	-1.3	-0.0	-1.0	-0.8
Eye problems/disorders: None of the above	0.7	0.9	2.1	0.5	0.7	1.3	-0.4	-0.6	0.8	1.5	1.2	0.8
Medication: Omeprazole	0.7	0.8	2.3	-1.2	0.4	-1.0	-0.6	-0.0	-0.6	-1.5	-0.8	-1.2
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.1	-0.3	-0.1	-0.9	0.5	1.3	-0.0	-1.8	-0.9	-0.7
Financial situation satisfaction	0.7	0.9	2.0	-1.0	-0.4	-1.3	-0.6	-0.4	-1.4	-0.5	-1.2	-1.1
Fractured/broken bones in last 5 years	0.7	0.9	2.2	0.3	0.4	-0.6	-0.5	-0.8	-1.3	-1.2	-1.5	-1.2
Major Depression (MDD)	0.6	0.7	1.3	-1.1	0.1	-0.2	-0.7	-0.9	-0.6	-0.9	-1.1	-1.1
Height	0.6	10.9	33.2	-0.4	-3.8	-5.8	1.0	0.6	-4.5	-1.5	-4.6	-2.2
Cardiovascular Disease	0.6	1.8	6.3	-1.5	-0.0	-1.8	-0.6	-0.8	-0.8	-2.5	-1.4	-1.1
Hypothyroidism (self reported)	0.6	1.3	2.9	-1.1	1.5	1.5	-1.7	-1.4	-0.7	0.9	0.2	-0.3
Lung FEV1/FVC ratio	0.6	2.9	10.4	1.0	2.5	3.2	-0.8	-0.5	1.9	0.7	1.6	0.9
Pack years adult smoking proportion	0.6	0.9	2.1	-0.1	1.1	-0.5	-1.1	-0.6	-0.5	-1.4	-0.9	-1.4
Fed-up feelings	0.6	1.1	3.0	0.0	1.7	0.5	-1.7	-1.5	-0.7	0.5	0.1	-0.5
Pulse wave reflection index	0.6	0.7	2.1	0.5	0.3	1.3	0.5	0.7	1.4	0.4	1.0	0.9
High blood pressure (siblings)	0.6	0.9	2.8	-0.2	-1.7	-1.4	0.7	-0.3	-0.6	-1.1	-1.1	-0.6
Back pain experienced in last month	0.6	0.8	2.9	-1.0	-0.2	-1.7	-0.2	0.3	-1.4	0.0	-0.8	-0.9
Guilty feelings	0.6	0.8	3.0	1.7	0.6	1.2	0.0	0.3	0.6	1.1	0.8	0.6
Tinnitus: Yes, now most or all of the time	0.6	0.7	3.1	-0.7	1.1	1.8	-0.4	-0.2	0.5	0.6	0.7	0.4
Basal cell carcinoma (self-reported)	0.6	0.7	1.3	-0.5	1.1	1.1	-1.1	-1.0	-0.5	0.9	0.3	-0.1
Pack years of smoking	0.6	0.9	2.0	-0.4	1.0	-0.6	-1.1	-0.5	-0.5	-1.3	-1.0	-1.4
Neuroticism (Nagel 2018)	0.5	1.1	2.3	1.5	0.3	0.0	0.4	0.7	1.2	1.3	1.2	1.4
Reaction Time	0.5	0.9	2.6	1.2	0.4	0.4	0.7	0.8	0.9	1.6	0.8	1.2
Crohns Disease (2012)	0.5	0.8	2.5	-0.2	0.8	0.8	-0.3	0.2	0.9	1.6	1.5	0.7
Neuroticism	0.5	1.2	3.8	1.2	0.7	0.8	-0.1	0.4	0.8	2.0	1.3	1.3
Hand grip strength (left)	0.5	1.3	3.2	1.0	-1.3	-1.0	1.8	1.6	0.8	-1.0	0.0	0.2
Ever had hysterectomy (womb removed)	0.5	0.5	1.9	-0.2	-1.4	-0.9	0.8	0.7	0.0	-0.4	-0.9	-0.2
Severe depression (siblings)	0.5	0.5	1.7	0.1	0.3	-0.1	-0.5	-0.6	-0.3	-0.9	-1.3	-1.1
Townsend deprivation index at recruitment	0.5	0.6	1.6	-0.2	1.2	0.3	-1.3	-0.9	-1.2	0.1	-0.3	-0.6
Average weekly fortified wine intake	0.5	0.5	1.4	-1.2	0.8	0.7	-0.9	-1.0	-0.1	0.6	0.1	0.2
Age when periods started (menarche)	0.5	1.2	2.5	0.8	-0.1	0.9	1.1	0.6	1.4	1.1	1.5	1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.2	-1.0	0.5	-0.2	-1.1	-0.6	-0.9	-1.2	-1.5	-1.5
Hayfever, allergic rhinitis or eczema	0.5	1.0	3.3	0.4	1.6	0.7	-0.0	0.9	0.4	1.8	1.2	0.7
Supplements: Glucosamine	0.5	0.7	1.7	0.3	0.9	1.1	-0.0	-0.3	0.9	1.1	1.3	0.7
Medication: Levothyroxine sodium	0.5	0.8	1.7	-0.8	0.4	0.5	-1.1	-1.0	-1.3	-0.8	-0.9	-0.9
Hearing difficulty/problems with background noise	0.5	0.8	1.8	-0.7	1.3	1.3	-1.1	-1.2	-0.5	0.3	-0.2	0.2
Had other major operations	0.5	0.6	1.5	0.2	1.0	1.2	-0.6	-0.9	-0.0	0.9	0.5	0.8
Medication: Ramipril	0.5	0.6	2.0	-0.5	-0.9	-1.0	0.2	-0.2	-0.5	-1.4	-0.9	-0.7
Neuroticism score	0.5	1.1	3.2	1.2	0.9	1.1	-0.4	-0.1	0.7	1.8	1.1	1.0
Happiness	0.5	0.6	1.7	0.0	1.3	0.5	-1.1	-0.7	-0.5	0.9	0.1	-0.6
Asthma	0.5	0.9	3.3	0.1	0.9	0.5	-0.0	0.7	1.1	0.7	1.8	1.2
Standing height	0.5	5.2	17.4	0.7	-3.4	-4.2	2.1	1.3	-2.4	-0.8	-2.2	-0.2
Exposure to tobacco smoke at home	0.5	0.5	1.1	-0.6	1.0	0.4	-1.0	-0.8	-0.4	-0.8	-0.4	-0.8
Hair/balding pattern: Pattern 4	0.5	1.2	3.2	0.8	-1.8	-0.7	1.8	1.7	0.7	-0.5	-0.3	-0.1
Eye problems/disorders: Cataract	0.5	0.5	1.5	-0.3	-0.8	-1.0	0.3	0.1	-0.5	-1.2	-0.8	-0.6
Miserableness	0.5	0.8	2.2	-0.3	-0.7	-1.5	-0.1	-0.3	-1.3	-0.8	-1.3	-0.7
Wears glasses or contact lenses	0.5	0.6	1.9	-0.3	0.4	1.0	0.2	0.1	0.9	0.6	1.2	1.4
Myopia	0.5	0.7	1.9	0.6	-1.3	-0.5	1.4	0.8	1.1	-0.9	-0.1	0.1
Depression (Nagel 2018)	0.4	0.6	1.4	-0.3	-0.1	-0.6	-0.8	-1.2	-0.8	-0.9	-1.0	-0.5
Breast Cancer	0.4	0.9	3.8	-0.3	-1.0	-1.3	0.0	-0.5	0.0	-1.9	-0.7	-0.6
Prostate Cancer	0.4	0.5	1.8	-0.1	0.7	1.3	-0.1	0.0	0.6	1.0	0.9	0.5
Rheumatoid Arthritis	0.4	0.6	1.9	0.2	-1.1	-1.4	0.9	0.7	0.2	-0.9	-0.1	0.1
Heel T-Score	0.4	3.5	6.4	1.6	1.3	2.5	0.3	0.7	2.4	2.5	2.4	1.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.5	-0.0	-0.1	-0.8	-0.6	-0.7	-1.2	0.7	-1.0	-0.3
Medication for hormone replacement therapy	0.4	0.4	1.0	-0.6	0.4	0.6	-0.1	0.2	0.5	0.9	1.0	0.8
Maternal smoking around birth	0.4	0.6	2.3	-0.4	0.5	0.2	-1.0	-0.8	-0.8	1.5	-0.3	-0.1
Qualifications: CSEs or equivalent	0.4	0.6	1.5	0.5	1.2	0.5	-0.5	-0.0	0.2	1.2	0.9	0.7
Stomach or abdominal pain in last month	0.4	0.4	2.2	-0.8	-0.7	-0.6	0.4	0.1	0.1	-1.5	-0.3	0.1
Chronic bronchitis/emphysema (father)	0.4	0.5	1.1	-0.8	0.6	-0.4	-0.8	-0.7	-0.5	-0.2	-1.0	-0.8
Number of incorrect matches in round	0.4	0.7	1.2	0.9	0.3	0.8	0.8	1.1	1.1	0.9	0.7	0.7
Past tobacco smoking	0.4	0.7	1.4	0.7	0.9	1.1	0.0	0.9	1.2	0.8	0.9	0.5
Father’s age at death	0.4	0.6	1.6	-0.4	0.5	-0.6	-0.8	-0.7	-1.3	-0.1	-0.7	-1.0
Falls in the last year	0.4	0.6	1.5	-0.2	1.2	0.8	-1.0	-0.6	-0.7	1.2	0.1	0.1
Noisy workplace	0.4	0.5	1.1	-0.2	0.7	0.2	-0.8	-0.7	-0.0	-0.7	-1.1	-1.0
Mouth/teeth dental problems: Dentures	0.4	0.7	1.4	-0.5	0.2	-0.7	-0.9	-0.6	-0.8	-1.1	-1.2	-1.0
Depression (self-reported)	0.4	0.5	1.2	1.1	-0.6	0.2	0.7	0.6	0.7	0.8	0.6	0.9
Medication: Lansoprazole	0.4	0.4	0.8	-0.7	0.7	-0.1	-0.9	-0.5	-0.6	-0.5	-0.6	-0.9
Medication: Paracetamol	0.4	0.6	1.8	1.4	-0.6	0.1	1.0	1.0	0.8	-0.4	0.2	0.4
Glaucoma (self-reported)	0.4	0.5	1.2	-0.3	1.0	0.7	-1.1	-0.7	-0.7	0.2	-0.5	-0.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.8	-0.8	0.8	0.9	-1.3	-1.3	-1.0	0.4	-0.3	-0.5
Number of full brothers	0.4	0.5	1.7	-0.4	-0.7	-1.3	0.3	0.5	-0.4	-0.6	-0.8	-0.7
Medication: Ibuprofen	0.4	0.4	2.2	0.7	-0.5	-0.2	0.2	0.1	0.0	-1.5	-0.6	-0.9
Medication: Allopurinol	0.4	0.5	1.9	-0.1	-1.4	-0.8	0.3	-0.6	0.0	-1.0	-0.5	0.0
Medication: Seretide 50 evohaler	0.4	0.4	2.0	0.4	0.8	0.5	-0.1	0.1	0.4	1.4	0.6	0.6
Number of full sisters	0.4	0.5	1.6	-0.2	1.3	-0.1	-1.0	-1.1	-0.6	0.8	0.0	-0.1
Chest pain or discomfort	0.4	0.6	1.5	-0.8	0.7	-0.1	-1.2	-1.0	-0.9	-0.2	-0.6	-0.7
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.4	1.2	-0.5	-0.5	1.0	1.1	0.3	0.5	0.1	0.4
Loneliness, isolation	0.4	0.5	1.3	0.6	1.2	0.4	-0.4	-0.7	0.0	1.1	0.5	1.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.0	-0.0	-1.4	-0.9	0.3	-0.5	-1.0	-1.1	-0.3	0.4
Asthma (self-reported)	0.4	0.8	3.0	-0.1	1.0	0.6	-0.3	0.5	0.9	0.7	1.7	1.1
Medication: Gliclazide	0.4	0.4	1.2	-0.5	0.2	-1.1	0.2	1.0	0.2	-0.9	-0.2	-0.6
Mother’s age at death	0.4	0.5	1.3	-0.3	1.1	0.7	-1.0	-1.1	-0.7	0.0	-0.1	-0.5
Medication: Lisinopril	0.4	0.5	1.8	-0.9	-0.7	-1.3	-0.2	-0.3	-0.8	-0.0	-0.4	-0.5
Ever smoked	0.4	0.7	1.6	-0.8	-0.8	-1.1	-0.1	-0.7	-1.3	-0.1	-0.9	-0.6
Irritability	0.4	0.7	1.5	0.4	-1.2	-1.2	0.8	0.7	0.3	-1.1	-0.4	-0.2
Commuting to job workplace: Cycle	0.4	0.5	1.2	0.7	-0.1	0.9	0.4	1.0	0.2	1.1	0.9	0.3
Alcohol drinker status: Previous	0.4	0.5	1.0	0.9	-1.0	0.5	0.7	0.3	0.8	1.0	0.0	0.6
Schizophrenia (2018)	0.3	0.6	1.3	-0.7	1.0	0.8	-0.3	-0.6	0.7	0.5	1.1	0.9
Schizophrenia vs Biploar Disorder	0.3	0.4	1.0	0.3	0.3	0.5	0.4	0.4	0.9	-0.3	1.0	1.0
Alzheimer’s Disease (in father)	0.3	0.3	0.7	-0.8	0.6	0.0	-0.7	-0.7	-0.8	0.3	-0.3	0.1
Body Mass Index (BMI) (2010)	0.3	0.5	1.4	0.7	0.8	1.2	-0.4	-0.2	-0.4	1.0	-0.4	-0.2
Mean Putamen Volume	0.3	0.3	0.6	-0.6	-0.8	-0.8	0.0	0.1	-0.4	-0.8	-0.6	-0.4
Fasting Glucose	0.3	0.3	0.8	0.5	-0.2	0.3	0.5	0.8	0.5	0.5	0.9	0.7
Neuroticism (2016)	0.3	0.4	1.0	0.5	-0.3	0.5	0.5	0.7	0.4	1.0	0.6	1.0
Triglycerides	0.3	0.5	1.1	0.2	-1.1	-0.2	0.3	0.2	-0.3	-0.9	-1.0	-1.0
Blood White Count	0.3	2.0	4.0	-1.5	0.7	-1.1	-1.3	-1.0	-2.0	-1.7	-1.4	-1.4
Allergy or Eczema	0.3	0.8	2.4	-0.1	1.5	0.6	-0.3	0.5	0.3	1.5	1.1	0.7
Chronotype (morning person)	0.3	0.6	1.9	-0.9	-0.8	-1.2	0.2	-0.4	-0.2	-1.4	-0.5	-0.2
Sensitivity / hurt feelings	0.3	0.5	1.2	1.0	0.7	0.8	-0.2	0.1	0.4	1.1	0.4	0.9
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.9	0.0	0.3	0.6	-0.9	-1.4	-0.6	0.1	-0.2	0.1
Relative age of first facial hair	0.3	0.7	1.2	-1.0	-0.3	-0.4	-0.7	-1.0	-1.0	-0.8	-1.1	-0.9
Ever used hormone-replacement therapy (HRT)	0.3	0.4	2.2	-0.2	-0.5	0.0	0.3	0.5	-0.1	1.5	0.5	0.8
Multivitamins +/- minerals	0.3	0.4	2.3	-0.6	-0.1	0.3	-0.6	-1.5	-0.2	-0.2	-0.0	0.3
Hair/balding pattern: Pattern 2	0.3	0.4	1.5	-0.7	1.2	0.4	-0.7	-0.7	-0.0	-0.3	0.1	-0.3
Had menopause	0.3	0.4	1.3	-0.0	-0.3	-0.0	0.8	1.1	0.8	0.5	0.3	0.8
Forced vital capacity (FVC)	0.3	1.0	5.1	0.3	-2.2	-1.0	1.5	0.4	0.1	-0.1	-0.3	0.5
Diabetes (self-reported)	0.3	0.5	1.1	-0.7	-0.6	-1.0	-0.1	-0.4	-0.4	-0.9	-0.9	-0.5
Medication: Simvastatin	0.3	0.5	2.6	-0.8	-0.5	-0.7	-0.2	-0.3	0.4	-1.6	-0.2	-0.4
Worrier / anxious feelings	0.3	0.6	1.7	0.7	0.3	-0.0	0.2	0.0	0.8	1.0	1.0	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.4	-0.3	0.4	-1.2	-0.5	-0.1	-1.0	-0.6	-1.0	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.7	1.0	-0.3	0.1	0.4	0.3	0.3	-1.3	-0.5	-0.8
Illnesses of mother	0.3	0.4	1.2	0.1	0.1	0.8	0.0	0.3	0.2	0.7	1.1	1.1
Breastfed as a baby	0.3	0.3	0.9	-0.3	0.7	0.6	-0.6	-1.0	0.2	0.1	0.8	0.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	1.3	0.2	-0.3	0.9	0.3	-0.4	0.4	1.1	0.8	0.7
Gout (self-reported)	0.3	0.4	0.9	0.1	-1.0	-0.2	0.8	0.2	0.7	-0.4	0.4	0.9
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.9	-0.6	0.6	-0.0	-0.6	-0.6	-0.6	0.2	-0.9	-0.3
Number of children fathered	0.3	0.4	1.4	-0.5	1.2	-0.1	-0.8	0.3	-0.5	0.3	-0.3	-0.8
Mean time to correctly identify matches	0.3	0.5	1.6	0.9	0.7	0.4	0.3	0.5	0.5	1.2	0.5	0.9
Suffer from ‘nerves’	0.3	0.5	1.2	-0.1	-1.1	-1.0	-0.0	-0.3	-0.3	-0.6	-1.1	-0.8
Family relationship satisfaction	0.3	0.4	1.4	0.8	0.6	0.1	-0.2	-0.5	0.3	1.2	0.6	0.7
Osteoporosis (self-reported)	0.3	0.4	1.1	0.4	1.0	0.7	-0.5	-0.4	0.3	1.0	0.6	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.4	-0.7	0.7	0.9	-1.1	-1.5	-0.1	-0.4	0.2	0.0
Average weekly beer plus cider intake	0.3	0.5	1.3	0.5	1.1	1.1	-0.9	-0.6	-0.3	0.4	-0.1	-0.4
Unable to work because of sickness or disability	0.3	0.4	0.8	0.8	-0.0	0.9	0.5	0.5	0.8	0.7	0.3	0.7
Bipolar Disorder or Schizophrenia	0.2	0.4	0.8	-0.6	0.6	0.8	0.1	-0.2	0.7	0.9	0.9	0.7
Crohns Disease (2017)	0.2	0.4	1.8	-0.5	0.0	0.2	-0.1	0.2	0.6	1.3	0.9	0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.4	0.9	-0.0	1.1	0.4	-0.1	-0.3	1.2	-0.1	0.4
LDL Cholesterol	0.2	0.4	1.2	1.1	0.3	0.9	0.2	0.9	0.6	0.2	0.1	0.2
Waist Hip Ratio (WHR)	0.2	0.7	1.8	-0.0	1.2	1.2	-1.1	-0.5	0.1	1.3	0.7	0.0
Respiratory disease	0.2	0.5	1.7	-1.3	0.8	-0.7	-0.9	-0.1	-0.7	-0.2	0.5	-0.1
Hair Pigment	0.2	4.4	11.0	0.4	-3.3	-3.0	1.8	0.8	-0.1	-3.3	-1.8	-1.3
Hand grip strength (right)	0.2	0.5	1.8	-0.3	-0.6	-1.3	0.4	0.4	-0.3	-1.3	-0.5	-0.5
Current tobacco smoking	0.2	0.4	1.3	-0.2	-0.5	-0.7	-0.0	0.1	-0.5	-0.8	-1.1	-0.8
Nervous feelings	0.2	0.3	1.0	0.5	-0.4	-0.7	0.6	0.4	0.5	0.2	0.4	1.0
Qualifications: None of the above	0.2	0.5	1.3	-0.7	0.4	0.2	-0.8	0.0	-1.0	-0.2	-1.0	-1.1
Allergy	0.2	0.4	1.4	0.7	-1.2	0.1	0.7	-0.3	0.1	-0.7	-0.5	-0.0
Number of live births	0.2	0.3	1.6	0.4	0.0	1.2	0.1	0.0	1.0	-0.0	0.4	0.1
Pulse rate	0.2	0.4	1.1	0.7	1.0	0.5	-0.6	-0.6	0.3	0.3	0.6	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.6	0.0	-0.7	-0.8	0.1	-0.4	-0.3	-0.8	-0.6	-0.5
Medication: Cholesterol lowering	0.2	0.3	1.1	0.1	0.6	-0.7	-0.5	0.1	0.1	-1.0	-0.2	-0.3
Prospective memory result	0.2	0.2	0.7	0.9	0.3	0.1	-0.3	-0.8	0.4	0.0	-0.1	-0.2
Lung cancer (father)	0.2	0.3	1.3	1.2	0.1	0.5	0.5	0.4	0.4	-0.2	0.1	0.3
Birth weight of first child	0.2	0.4	0.8	-0.1	0.5	0.3	-0.8	-0.9	-0.9	0.2	-0.8	-0.8
Qualifications: O levels/GCSEs or equivalent	0.2	0.2	1.4	-0.5	-0.0	0.0	0.0	-0.1	0.1	-1.2	-0.1	-0.7
Blood clot in the leg (DVT)	0.2	0.2	0.6	-0.6	-0.4	-0.7	0.2	-0.2	0.4	-0.8	-0.3	-0.4
Medication: Amlodipine	0.2	0.3	0.8	0.4	-0.4	-0.1	0.7	0.7	0.9	-0.3	0.3	0.5
Forced vital capacity (FVC), Best measure	0.2	0.6	2.6	0.1	-1.6	-1.1	1.0	0.1	-0.2	-0.2	-0.4	0.1
Comparative body size at age 10	0.2	0.6	1.7	-0.9	0.3	-0.6	-1.0	-0.8	-1.3	-0.2	-1.0	-0.4
Wheeze or whistling in the chest in last year	0.2	0.4	1.1	-0.9	0.1	-1.1	-0.3	0.1	-0.8	-0.6	-0.7	-0.3
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.0	1.0	0.4	0.4	-0.0	0.3	-0.4	0.8	-0.0	0.0
Medication: Blood pressure	0.2	0.3	0.5	-0.2	0.4	-0.5	-0.6	-0.4	-0.6	-0.6	-0.7	-0.6
Mood swings	0.2	0.3	0.7	-0.3	0.2	-0.3	-0.8	-0.6	-0.7	-0.6	-0.5	-0.6
Ever had bowel cancer screening	0.2	0.2	0.7	-0.5	0.1	0.1	-0.7	-0.8	-0.5	-0.4	-0.1	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.8	0.6	-0.9	0.0	0.8	0.6	0.4	-0.3	0.2	0.3
Ever taken oral contraceptive pill	0.2	0.2	0.7	-0.2	-0.9	-0.3	0.0	-0.6	-0.0	0.0	-0.4	-0.7
Commuting to job workplace: Public transport	0.2	0.2	0.6	0.2	-0.2	0.6	0.2	-0.7	0.5	0.4	0.5	0.7
Eye problems/disorders: Glaucoma	0.2	0.2	0.9	-0.1	0.9	0.1	-0.6	-0.2	-0.4	0.0	-0.1	-0.3
High cholesterol (Self-reported)	0.2	0.4	1.6	-0.3	1.3	0.2	-0.6	0.2	0.6	0.2	1.0	0.7
Medication: Bendroflumethiazide	0.2	0.3	0.7	-0.7	0.8	0.5	-0.6	-0.3	0.1	0.1	-0.5	-0.6
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.6	0.2	0.1	-0.2	-0.2	0.3	-0.4	-0.5	-0.5	-0.8
Cholesterol lowering medication	0.2	0.3	0.9	-0.6	1.0	0.5	-0.8	-0.5	0.6	-0.4	0.1	0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.7	-0.5	-0.3	-0.5	0.3	-0.1	0.5	-0.8	-0.1	-0.3
Bipolar Disorder (2018)	0.1	0.1	0.6	-0.1	-0.3	0.3	0.4	0.4	0.3	0.8	0.0	0.0
Depressed Affect (Nagel 2018)	0.1	0.2	0.4	0.6	0.6	-0.3	-0.5	-0.2	-0.1	0.5	0.3	0.4
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.7	0.4	-0.5	0.0	0.8	0.5	-0.3	0.6	-0.3	0.2
Age at First Birth	0.1	0.2	0.6	0.1	-0.1	0.1	0.1	0.1	-0.6	0.8	0.5	0.6
Coronary Artery Disease (CAD)	0.1	0.2	0.7	-0.6	0.4	0.8	-0.4	-0.2	0.3	-0.1	-0.2	-0.3
HbA1C	0.1	0.2	0.4	-0.1	-0.6	-0.6	0.5	0.5	0.1	-0.5	-0.0	0.1
Lupus	0.1	0.2	0.6	-0.6	-0.2	-0.7	-0.1	-0.1	-0.3	-0.8	-0.1	0.1
Blood Platelet Count	0.1	0.7	1.9	-1.4	0.8	0.0	-0.9	-0.7	-0.8	-1.1	-0.1	-0.5
Systolic Blood Pressure	0.1	0.7	1.5	0.7	-0.5	-0.2	1.0	0.9	1.2	-0.3	0.9	1.0
Lung FVC	0.1	0.5	2.0	-0.4	-1.4	-0.1	0.5	-0.4	0.6	-1.0	-0.2	-0.5
Tanning	0.1	1.0	2.0	-0.9	-0.9	-1.4	-0.5	-1.1	-0.9	-0.9	-1.2	-1.0
Relative age voice broke	0.1	0.2	0.9	-0.2	-0.9	-0.7	0.4	-0.0	0.2	0.1	0.2	0.4
High blood pressure (mother)	0.1	0.1	0.2	-0.1	0.4	-0.5	0.1	-0.1	0.3	-0.1	0.4	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.5	0.5	-0.2	-0.7	0.2	0.3	-0.5	0.2	-0.6	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.7	0.0	0.5	0.5	-0.6	-0.5	-0.0	-0.8	-0.8	-0.6
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.5	0.4	-0.1	0.1	-0.2	-0.3	-0.4	0.0	-0.4	-0.7
Fluid intelligence score	0.1	0.3	1.0	0.1	-0.4	0.1	0.6	0.2	-0.5	-0.1	-1.0	-0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.6	0.5	-1.3	0.1	1.0	-0.1	0.6	0.1	0.1	0.5
Length of working week for main job	0.1	0.1	0.6	-0.4	-0.3	-0.8	0.3	0.4	-0.1	0.1	-0.1	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.5	-0.2	-0.0	0.4	-0.4	-0.7	-0.1	-0.4	-0.3	-0.1
Peak expiratory flow (PEF)	0.1	0.3	1.2	-0.6	-0.3	0.7	-0.3	-1.1	0.1	-0.4	0.0	0.2
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.4	-0.6	-0.2	-0.6	0.2	0.3	0.1	-0.1	0.5	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.2	0.5	0.4	-0.1	0.1	-0.2	0.1	-0.3	0.3
Pulse rate, automated reading	0.1	0.2	0.8	0.9	0.1	-0.2	0.1	0.1	-0.1	0.2	-0.6	-0.5
Overall health rating	0.1	0.3	0.6	-0.1	0.5	-0.8	-0.6	-0.5	-0.1	-0.7	-0.6	-0.1
Leg pain on walking	0.1	0.1	0.3	-0.1	-0.0	-0.5	-0.3	-0.3	-0.6	0.5	-0.3	0.4
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.4	0.2	-0.6	-0.0	0.4	0.3	-0.0	0.3	0.0	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.5	-0.4	0.1	0.1	-0.3	-0.7	-0.3	0.2	-0.2	-0.4
Smoking status: Current	0.1	0.2	0.9	-0.1	-0.3	-0.4	-0.1	-0.0	-0.3	-0.5	-0.9	-0.7
Average weekly champagne plus white wine intake	0.1	0.2	0.8	0.0	0.2	-0.0	-0.3	-0.1	-0.4	0.1	-0.6	-0.9
Diastolic blood pressure, automated reading	0.1	0.3	0.9	-0.1	-0.2	-0.3	-0.3	-1.0	-0.5	-0.8	-0.7	-0.5
Blood Red Count	0.0	0.2	0.5	-0.4	-0.7	-0.6	0.1	0.1	-0.4	-0.4	-0.6	-0.2
Systolic blood pressure, automated reading	0.0	0.1	0.1	0.0	-0.3	-0.1	0.3	-0.1	0.3	-0.3	0.2	0.3
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.1	0.4	-0.0	-0.3	-0.1	0.0	0.1	-0.0	0.0	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.4	0.4	-0.7	0.0	0.6	-0.1	0.3	0.1	0.0	0.4
Qualifications: nursing, teaching	0.0	0.1	0.3	0.4	0.1	0.2	0.0	-0.5	0.1	-0.1	-0.0	0.3

Hub : Genes

VHL

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Trait associations