Best TWAS P=7.87e-09 · Best GWAS P=1.04e-07 conditioned to 0.423
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | EXOG | 0.18 | 0.08 | lasso | 4 | 0.05 | 1.7e-02 | -5.3 | -5.3 | 1.4e-07 | 0.99 | 0.03 | 0.86 | FALSE |
| 2 | GTEx | Colon Transverse | XYLB | 0.08 | 0.03 | enet | 15 | 0.05 | 1.7e-03 | -5.3 | 5.8 | 7.9e-09 | -0.85 | 0.03 | 0.93 | TRUE |
| 3 | GTEx | Esophagus Mucosa | EXOG | 0.13 | 0.05 | lasso | 3 | 0.03 | 5.0e-03 | -5.1 | -5.2 | 2.2e-07 | 0.98 | 0.04 | 0.91 | FALSE |
| 4 | GTEx | Nerve Tibial | EXOG | 0.10 | 0.00 | lasso | 5 | 0.00 | 1.7e-01 | -5.1 | -5.2 | 1.7e-07 | 0.87 | 0.03 | 0.82 | FALSE |
| 5 | GTEx | Pancreas | EXOG | 0.22 | 0.08 | enet | 15 | 0.03 | 2.6e-02 | -5.3 | -5.1 | 2.8e-07 | 0.91 | 0.03 | 0.93 | FALSE |
| 6 | GTEx | Stomach | EXOG | 0.14 | 0.05 | lasso | 6 | 0.02 | 2.5e-02 | -5.1 | -5.2 | 2.1e-07 | 1.00 | 0.02 | 0.95 | FALSE |
| 7 | GTEx | Testis | EXOG | 0.35 | 0.28 | lasso | 5 | 0.26 | 8.1e-12 | -5.3 | -5.4 | 8.4e-08 | 1.00 | 0.02 | 0.98 | FALSE |
| 8 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | EXOG | 0.02 | 0.02 | blup | 56 | 0.01 | 1.0e-02 | -5.1 | -5.2 | 2.3e-07 | 0.96 | 0.02 | 0.88 | FALSE |