TWAS hub - EXOG

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0990	0.0450	8.2e-03	-0.001	NA	0.004	NA	-0.001	3.6e-01	NA	1.3e-01	NA	4.3e-01
2	GTEx	Brain Cerebellum	0.1860	0.0760	1.6e-03	0.230	NA	0.210	NA	0.200	2.0e-07	NA	7.8e-07	NA	1.5e-06
3	GTEx	Brain Frontal Cortex BA9	0.1771	0.0791	7.9e-03	0.082	NA	0.011	NA	0.052	3.5e-03	NA	1.6e-01	NA	1.7e-02
4	GTEx	Breast Mammary Tissue	0.0810	0.0380	7.9e-03	0.056	NA	0.055	NA	0.050	7.3e-04	NA	8.6e-04	NA	1.4e-03
5	GTEx	Esophagus Mucosa	0.1280	0.0500	1.6e-03	0.052	NA	0.014	NA	0.029	2.2e-04	NA	4.0e-02	NA	5.0e-03
6	GTEx	Nerve Tibial	0.0996	0.0451	8.5e-03	0.002	NA	0.000	NA	0.004	2.3e-01	NA	3.3e-01	NA	1.7e-01
7	GTEx	Ovary	0.3330	0.0890	9.7e-05	0.246	NA	0.170	NA	0.207	9.8e-07	NA	5.7e-05	NA	8.1e-06
8	GTEx	Pancreas	0.2160	0.0810	2.5e-04	0.077	NA	0.027	NA	0.024	3.6e-04	NA	2.6e-02	NA	3.5e-02
9	GTEx	Stomach	0.1440	0.0580	2.0e-03	0.045	NA	0.023	NA	0.024	3.2e-03	NA	2.7e-02	NA	2.5e-02
10	GTEx	Testis	0.3500	0.0830	5.8e-10	0.275	NA	0.176	NA	0.258	1.2e-12	NA	3.1e-08	NA	8.1e-12
11	GTEx	Thyroid	0.1850	0.0460	9.1e-10	0.199	NA	0.165	NA	0.187	3.7e-15	NA	1.2e-12	NA	2.9e-14
12	NTR	Blood	0.0234	0.0074	2.6e-06	0.028	0.021	0.025	0.022	0.029	1.5e-09	1.7e-07	1.1e-08	9.7e-08	1.0e-09
13	ROSMAP	Brain Pre-frontal Cortex	0.0954	0.0251	6.4e-11	0.130	0.078	0.105	0.102	0.119	2.4e-16	2.9e-10	2.2e-13	5.1e-13	4.8e-15
14	TCGA	Bladder Urothelial Carcinoma	0.0690	0.0350	5.5e-04	0.005	0.036	0.035	NA	0.023	1.1e-01	4.6e-04	5.4e-04	NA	4.5e-03
15	TCGA	Colon Adenocarcinoma	0.2240	0.0840	5.7e-04	0.000	0.061	0.055	NA	0.006	3.2e-01	2.0e-04	4.1e-04	NA	1.3e-01
16	TCGA	Glioblastoma Multiforme	0.2850	0.1090	7.2e-04	0.053	0.110	0.101	NA	0.107	1.0e-02	3.2e-04	5.7e-04	NA	3.9e-04
17	TCGA	Head and Neck Squamous Cell Carcinoma	0.0396	0.0206	8.0e-04	0.009	0.030	0.026	NA	0.021	3.0e-02	2.3e-04	5.8e-04	NA	2.0e-03
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0806	0.0325	6.8e-07	0.023	0.064	0.056	NA	0.048	1.0e-03	9.1e-08	6.1e-07	NA	3.5e-06
19	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1450	0.0620	3.4e-06	0.090	0.088	0.066	NA	0.072	7.6e-06	9.5e-06	1.2e-04	NA	6.0e-05
20	TCGA	Lung Adenocarcinoma	0.0622	0.0277	1.2e-04	0.010	0.027	0.026	NA	0.024	2.0e-02	3.7e-04	4.8e-04	NA	7.3e-04
21	TCGA	Lung Squamous Cell Carcinoma	0.0162	0.0101	5.3e-03	0.018	0.013	0.002	NA	0.013	3.1e-03	1.0e-02	1.8e-01	NA	1.2e-02
22	TCGA	Pheochromocytoma and Paraganglioma	0.0970	0.0560	5.3e-03	0.020	0.031	0.007	NA	0.023	5.4e-02	2.1e-02	1.7e-01	NA	4.1e-02
23	TCGA	Prostate Adenocarcinoma	0.0617	0.0348	4.2e-03	0.006	0.025	0.022	NA	0.013	7.5e-02	9.9e-04	2.0e-03	NA	1.4e-02
24	TCGA	Thyroid Carcinoma	0.1140	0.0430	9.9e-09	0.051	0.098	0.083	NA	0.077	9.0e-06	9.5e-10	1.8e-08	NA	5.3e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Impedance of arm (right)	21.8	101.5	139.2	10.5	11.5	11.7	10.8	11.6	10.4	11.1	10.4	11.7	11.8	11.5	-11.0	11.0	7.2	7.3	3.0	10.3	9.2	11.0	6.2	11.8	10.2	3.1	9.9
Impedance of arm (left)	20.4	94.6	132.2	10.4	11.0	11.4	10.6	11.1	9.8	10.7	10.3	11.3	11.5	11.1	-10.9	10.5	6.7	7.1	2.5	9.9	8.7	10.6	5.8	11.5	9.8	3.0	9.5
Impedance of whole body	14.9	75.8	108.2	9.3	9.8	10.3	9.5	10.0	8.7	9.3	9.1	10.1	10.3	9.9	-9.8	9.4	6.1	6.4	2.2	8.9	7.9	9.4	5.0	10.4	9.0	2.7	8.3
Arm predicted mass (right)	8.6	43.9	64.3	-7.1	-7.8	-7.8	-8.0	-8.0	-6.3	-7.6	-6.9	-7.8	-7.9	-7.7	6.9	-7.3	-4.4	-3.9	-1.7	-6.5	-5.8	-7.3	-3.8	-7.6	-6.2	-1.2	-6.6
Arm fat-free mass (right)	8.2	42.2	64.0	-6.8	-7.7	-7.7	-8.0	-7.8	-6.2	-7.6	-6.6	-7.7	-7.8	-7.6	6.8	-7.2	-4.1	-4.0	-1.5	-6.3	-5.6	-7.2	-3.6	-7.5	-6.0	-1.1	-6.5
Arm predicted mass (left)	7.0	35.6	53.4	-6.5	-7.0	-7.0	-7.3	-7.1	-5.7	-6.8	-6.4	-7.1	-7.2	-7.0	6.4	-6.5	-3.7	-3.5	-1.1	-5.8	-5.1	-6.6	-3.1	-6.9	-5.6	-1.0	-5.9
Trunk fat-free mass	6.9	39.6	63.7	-6.8	-7.4	-7.4	-8.0	-7.5	-5.9	-7.4	-6.5	-7.4	-7.6	-7.3	6.7	-6.9	-4.1	-3.8	-1.3	-6.2	-5.3	-6.9	-3.6	-7.3	-5.8	-0.9	-6.2
Arm fat-free mass (left)	6.9	35.2	53.6	-6.4	-7.0	-7.0	-7.3	-7.1	-5.7	-6.9	-6.3	-7.0	-7.1	-7.0	6.3	-6.5	-3.7	-3.7	-1.1	-5.7	-5.0	-6.6	-3.2	-6.8	-5.4	-0.7	-5.9
Trunk predicted mass	6.8	39.0	61.9	-6.7	-7.3	-7.4	-7.9	-7.4	-5.9	-7.4	-6.5	-7.3	-7.5	-7.2	6.7	-6.8	-4.1	-3.6	-1.3	-6.1	-5.3	-6.9	-3.6	-7.2	-5.8	-0.9	-6.2
Alcohol intake frequency.	6.5	15.1	26.8	2.4	4.9	4.7	4.1	4.9	4.3	4.5	4.4	4.8	4.7	4.9	-5.2	4.9	2.1	2.4	-0.1	3.3	2.5	4.1	1.8	4.8	3.3	-0.2	3.3
Impedance of leg (left)	5.9	28.9	42.2	5.7	5.9	6.3	5.9	6.1	5.1	5.4	5.5	6.2	6.5	6.0	-6.0	5.7	4.3	4.1	1.6	5.6	5.1	5.7	3.3	6.5	5.8	2.1	5.0
Whole body water mass	5.7	32.3	53.2	-6.2	-6.7	-6.7	-7.3	-6.8	-5.4	-6.6	-5.9	-6.7	-6.8	-6.6	6.0	-6.2	-3.6	-3.4	-1.1	-5.5	-4.8	-6.3	-3.1	-6.5	-5.2	-0.8	-5.6
Bilateral oophorectomy (both ovaries removed)	5.6	6.5	13.1	-2.8	-2.5	-2.7	-2.4	-2.6	-1.7	-2.4	-2.6	-2.6	-2.7	-2.5	2.1	-2.5	-2.4	-0.9	-1.9	-3.0	-3.5	-2.7	-2.3	-2.9	-3.6	-1.6	-2.4
Whole body fat-free mass	5.6	32.0	52.4	-6.2	-6.6	-6.6	-7.2	-6.8	-5.4	-6.6	-5.9	-6.7	-6.8	-6.6	5.9	-6.2	-3.6	-3.4	-1.2	-5.5	-4.8	-6.2	-3.1	-6.5	-5.2	-0.9	-5.6
Impedance of leg (right)	5.5	26.7	40.3	5.9	5.8	6.2	5.6	6.0	5.3	5.2	5.1	6.0	6.2	5.8	-6.0	5.5	3.7	4.0	1.1	5.3	4.6	5.5	2.8	6.3	5.5	1.5	4.7
Falls in the last year	5.5	7.4	11.0	1.6	3.1	3.2	2.7	3.3	2.5	2.3	2.4	3.1	3.2	3.2	-2.7	3.3	2.4	1.9	1.9	3.2	2.7	2.6	2.2	3.1	2.8	2.1	3.0
Birth weight	5.5	11.8	21.7	-4.7	-4.1	-4.0	-4.3	-4.2	-3.3	-4.0	-3.7	-3.9	-3.9	-4.0	4.4	-4.1	-2.7	0.6	-0.2	-3.0	-2.4	-2.5	-2.2	-4.2	-3.5	-0.2	-2.4
Chronotype (morning person)	4.6	10.7	16.5	1.3	3.9	3.7	3.6	4.1	3.0	3.0	4.1	3.8	3.8	3.9	-3.5	3.8	3.5	0.6	1.7	3.2	3.3	3.1	2.8	3.8	3.8	1.3	2.8
Maternal smoking around birth	4.6	6.7	11.4	-1.6	-2.8	-2.9	-2.4	-2.9	-2.7	-2.3	-2.8	-2.8	-2.9	-2.8	2.2	-2.6	-2.4	-1.0	-2.2	-3.1	-3.0	-2.1	-2.3	-3.0	-3.4	-2.5	-2.5
Number of incorrect matches in round	4.5	7.4	14.1	-2.2	-3.3	-3.6	-3.5	-3.4	-2.1	-3.0	-2.9	-3.4	-3.5	-3.3	3.8	-3.0	-1.8	-1.3	-0.2	-2.4	-1.9	-2.8	-1.3	-3.4	-2.5	0.0	-2.2
Hand grip strength (left)	4.4	11.5	20.6	-3.9	-4.0	-4.1	-4.5	-4.1	-3.8	-3.8	-3.9	-4.0	-4.2	-4.0	4.4	-3.9	-1.6	-1.7	0.8	-3.0	-1.6	-2.8	-0.9	-4.5	-2.9	-0.6	-2.4
Hand grip strength (right)	4.4	11.9	23.4	-3.1	-4.3	-4.3	-4.8	-4.1	-3.8	-4.0	-3.7	-4.3	-4.4	-4.3	4.3	-4.2	-2.0	-2.4	1.0	-2.5	-1.3	-3.1	-1.1	-4.3	-2.3	0.1	-2.7
Basal metabolic rate	4.4	24.6	41.0	-5.5	-5.9	-5.9	-6.4	-6.0	-4.8	-5.7	-5.2	-5.9	-6.0	-5.8	5.1	-5.4	-3.0	-2.9	-0.9	-4.7	-4.2	-5.5	-2.5	-5.7	-4.5	-0.6	-4.9
Schizophrenia (2014)	4.1	8.9	20.4	-2.8	-3.5	-3.8	-2.7	-3.4	-2.6	-3.6	-2.1	-3.6	-3.8	-3.4	4.5	-3.2	0.2	-3.5	1.3	-2.5	-1.8	-4.1	0.3	-3.8	-2.1	1.2	-2.4
Comparative body size at age 10	4.0	10.9	15.3	-0.8	-3.5	-3.7	-3.1	-3.6	-3.2	-3.0	-3.2	-3.7	-3.9	-3.6	3.3	-3.5	-2.9	-3.7	-1.7	-3.7	-3.7	-3.9	-2.3	-3.8	-3.9	-2.1	-3.4
Reason for reducing amount of alcohol drunk: Health precaution	4.0	4.7	7.7	-0.6	-2.5	-2.8	-2.8	-2.5	-1.8	-2.5	-2.6	-2.5	-2.6	-2.6	2.3	-2.6	-1.8	-0.2	-0.7	-2.1	-1.9	-2.1	-1.8	-2.6	-2.2	-0.4	-2.1
Mouth/teeth dental problems: Bleeding gums	3.9	5.1	11.1	-2.0	-2.1	-2.0	-1.6	-2.2	-1.2	-2.2	-2.9	-2.2	-2.3	-2.2	2.5	-2.2	-2.3	-1.1	-1.6	-2.9	-2.4	-1.5	-2.5	-2.9	-3.3	-2.5	-2.0
Number of operations (self-reported)	3.8	5.6	10.0	1.8	3.1	3.0	2.9	2.9	2.6	2.8	2.4	3.1	3.2	3.1	-2.9	3.0	0.3	1.9	-1.6	1.1	0.6	2.8	-0.2	2.7	0.9	-1.8	1.6
Ever had hysterectomy (womb removed)	3.7	4.1	7.9	-2.2	-2.3	-2.0	-2.1	-2.3	-1.8	-2.7	-2.8	-2.2	-2.1	-2.3	2.2	-2.3	-1.4	1.2	-0.8	-1.7	-2.2	-1.5	-1.7	-2.4	-2.7	-0.3	-1.2
BMI	3.3	18.9	28.7	-4.2	-5.1	-5.3	-4.7	-5.2	-5.2	-4.4	-5.1	-5.2	-5.4	-5.1	4.8	-4.7	-2.0	-2.5	-0.6	-4.0	-4.2	-5.1	-1.5	-5.2	-4.5	-0.4	-3.8
Loud music exposure frequency	3.3	3.6	6.4	0.9	2.3	2.1	2.5	2.4	0.9	1.9	1.4	2.3	2.2	2.3	-1.7	2.1	1.4	1.8	0.8	2.0	2.1	2.5	0.9	2.1	1.8	0.9	2.2
Average weekly red wine intake	3.1	4.6	8.9	-1.4	-2.3	-2.6	-2.1	-2.3	-1.8	-2.3	-2.1	-2.4	-2.5	-2.3	2.6	-2.5	-3.0	-0.9	-1.3	-2.1	-1.8	-1.4	-2.4	-2.5	-2.5	-1.3	-1.8
Osteoporosis (self-reported)	3.1	3.9	7.3	1.9	2.4	2.4	2.3	2.3	1.6	2.0	2.6	2.4	2.3	2.5	-2.7	2.5	0.2	2.0	-0.8	1.4	0.6	2.3	0.3	2.4	1.0	-0.4	1.7
Diabetes (mother)	3.0	3.9	8.8	-1.6	-2.4	-2.3	-2.1	-2.2	-2.0	-3.0	-2.4	-2.3	-2.3	-2.2	2.7	-2.3	-1.5	0.3	0.2	-1.8	-1.0	-1.5	-1.5	-2.6	-1.9	0.1	-1.4
Age when periods started (menarche)	3.0	7.2	13.7	0.1	3.0	3.1	2.4	2.9	2.6	3.3	2.7	3.0	3.1	2.9	-3.7	2.9	2.8	0.9	0.6	2.4	3.0	3.1	2.3	3.4	3.5	-0.1	1.9
Leg predicted mass (right)	3.0	15.9	29.2	-4.6	-4.8	-4.7	-5.4	-4.9	-3.9	-4.5	-4.0	-4.8	-4.9	-4.7	4.1	-4.3	-2.3	-2.4	-0.6	-3.7	-3.2	-4.4	-1.9	-4.6	-3.5	-0.4	-3.9
Schizophrenia (2018)	2.9	6.0	16.1	-2.5	-3.0	-3.2	-2.1	-2.9	-1.7	-2.5	-1.7	-3.0	-3.1	-3.0	4.0	-2.7	0.0	-2.7	1.4	-2.1	-1.3	-3.1	0.4	-3.3	-1.8	0.8	-1.9
Lung FVC	2.9	14.9	22.8	-4.3	-4.3	-4.4	-4.6	-4.3	-4.0	-4.8	-3.3	-4.3	-4.4	-4.2	4.1	-4.1	-3.4	-1.7	-1.6	-4.2	-3.2	-3.2	-3.5	-4.7	-4.1	-1.8	-3.6
Leg fat-free mass (left)	2.9	15.3	27.5	-4.2	-4.7	-4.6	-5.2	-4.8	-3.7	-4.4	-4.0	-4.7	-4.8	-4.6	4.0	-4.3	-2.3	-2.4	-0.7	-3.7	-3.3	-4.4	-1.9	-4.5	-3.5	-0.5	-3.8
Leg predicted mass (left)	2.9	15.4	27.9	-4.3	-4.7	-4.6	-5.3	-4.8	-3.7	-4.5	-4.0	-4.7	-4.8	-4.6	4.0	-4.3	-2.3	-2.4	-0.7	-3.7	-3.3	-4.4	-1.9	-4.5	-3.5	-0.5	-3.9
Illnesses of siblings	2.9	4.0	6.5	1.9	2.4	2.3	1.8	2.3	2.3	2.0	2.2	2.4	2.2	2.5	-1.8	2.6	2.0	0.2	1.0	1.8	1.9	1.9	1.7	2.2	2.0	0.9	2.0
Qualifications: NVQ or HND or HNC or equivalent	2.9	3.5	6.1	-1.5	-2.2	-2.2	-2.2	-2.2	-1.5	-2.3	-2.3	-2.2	-2.2	-2.1	2.1	-2.3	-1.1	-0.4	-0.4	-2.0	-1.5	-1.5	-1.1	-2.5	-2.1	-1.0	-1.6
Leg fat-free mass (right)	2.9	15.4	28.1	-4.5	-4.7	-4.7	-5.3	-4.8	-3.8	-4.5	-3.9	-4.7	-4.8	-4.6	4.1	-4.3	-2.2	-2.3	-0.5	-3.7	-3.1	-4.4	-1.8	-4.5	-3.4	-0.2	-3.7
Medication: Paracetamol	2.8	4.3	8.2	1.4	2.5	2.6	2.9	2.5	2.0	2.4	2.0	2.5	2.7	2.4	-2.3	2.4	1.6	1.4	-0.1	1.8	1.4	2.2	1.2	2.4	1.5	0.5	2.2
Time employed in main current job	2.6	3.0	7.9	-0.9	-1.8	-1.9	-2.6	-1.9	-2.2	-2.3	-2.1	-1.9	-2.1	-1.9	2.8	-1.7	-0.1	0.1	1.1	-1.1	-1.0	-1.8	-0.1	-2.4	-1.8	1.2	-0.5
Tense / ‘highly strung’	2.6	4.4	8.3	-1.8	-2.5	-2.5	-2.3	-2.4	-2.9	-2.7	-2.2	-2.5	-2.5	-2.5	2.1	-2.5	-1.5	-1.0	-0.4	-1.8	-1.6	-2.2	-1.4	-2.4	-1.7	-0.5	-1.9
Financial situation satisfaction	2.6	3.2	8.1	0.9	1.6	1.7	1.4	1.7	2.2	1.6	1.5	1.7	1.7	1.6	-0.6	1.6	2.1	1.2	2.3	2.0	2.9	2.1	2.0	1.3	2.3	1.3	2.0
Supplements: Fish oil (including cod liver oil)	2.6	3.3	7.9	-1.6	-2.1	-2.0	-2.1	-2.1	-1.6	-2.8	-2.3	-2.1	-2.2	-1.9	2.3	-1.9	-1.3	-0.9	-0.4	-1.8	-1.4	-2.0	-1.5	-2.0	-1.5	0.5	-1.7
Relative age voice broke	2.5	3.8	6.6	0.8	2.5	2.5	2.2	2.3	1.8	2.0	1.7	2.5	2.4	2.6	-1.6	2.4	1.8	1.6	1.0	1.8	1.3	1.9	1.7	2.0	1.3	1.0	2.5
Worry too long after embarrassment	2.5	4.2	6.5	-2.3	-2.2	-2.1	-1.8	-2.3	-2.5	-1.9	-2.4	-2.2	-2.2	-2.2	2.0	-2.0	-1.9	-1.0	-1.2	-2.4	-2.1	-2.0	-1.8	-2.5	-2.5	-1.3	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	2.5	3.2	6.0	-1.3	-1.7	-1.6	-1.7	-1.7	-0.9	-1.7	-2.3	-1.7	-1.7	-1.5	1.9	-1.5	-2.4	-0.7	-1.5	-2.3	-1.6	-0.8	-2.3	-2.0	-2.2	-2.5	-1.9
Mouth/teeth dental problems: Loose teeth	2.4	2.9	7.1	-0.0	-1.9	-1.8	-1.3	-2.0	-1.3	-1.3	-1.6	-1.9	-1.9	-1.9	2.0	-2.0	-1.0	-0.9	-0.8	-1.7	-2.7	-2.6	-0.9	-1.9	-2.3	-0.6	-1.6
Bipolar Disorder or Schizophrenia	2.3	5.6	12.5	-2.4	-2.8	-3.1	-2.3	-2.6	-1.8	-2.6	-1.4	-2.9	-3.0	-2.9	3.5	-2.5	0.1	-2.4	1.0	-2.0	-1.5	-3.2	0.1	-3.0	-1.7	0.7	-2.0
Bipolar Disorder (2011)	2.2	2.1	6.0	-0.7	-1.2	-1.3	-1.7	-1.4	-1.4	-1.7	-0.7	-1.2	-1.2	-1.3	1.0	-1.0	-1.2	-1.1	-1.4	-2.0	-2.5	-2.1	-1.5	-1.4	-2.1	-0.8	-1.6
Diabetes (father)	2.2	2.7	5.3	-1.4	-1.5	-1.6	-1.4	-1.6	-2.3	-1.1	-1.7	-1.5	-1.5	-1.6	0.5	-1.5	-2.2	-0.4	-2.3	-1.8	-1.9	-1.2	-2.3	-1.1	-1.7	-1.6	-2.0
Tinnitus: Yes, but not now, but have in the past	2.2	2.4	4.8	1.5	1.8	1.9	2.2	1.7	0.7	2.1	0.6	1.8	1.9	1.8	-1.2	1.9	0.9	2.2	1.1	1.6	0.8	1.3	1.3	1.3	0.4	0.8	2.1
Osteoarthritis (self-reported)	2.2	2.9	6.2	0.6	2.3	2.1	2.2	2.4	1.7	2.1	1.9	2.2	2.1	2.3	-2.1	2.5	0.5	0.5	-0.4	1.2	0.4	1.6	0.5	2.0	0.9	-0.8	1.3
Medication: Allopurinol	2.1	2.8	6.8	-1.4	-1.6	-1.9	-1.3	-1.7	-1.1	-1.1	-0.9	-1.7	-1.8	-1.7	0.3	-1.6	-1.9	-0.8	-2.3	-1.9	-2.6	-1.8	-1.7	-1.2	-1.9	-1.9	-2.2
Body mass index (BMI)	2.0	8.7	12.7	-3.3	-3.5	-3.5	-2.8	-3.5	-3.3	-2.5	-3.5	-3.5	-3.5	-3.4	2.8	-3.2	-1.4	-2.1	-0.8	-2.9	-3.2	-3.6	-0.9	-3.5	-3.2	-0.8	-2.8
Number of full sisters	2.0	2.4	3.9	-0.4	1.7	1.7	0.8	1.9	1.9	1.4	1.2	1.8	1.8	1.8	-1.0	1.7	1.3	1.0	1.4	1.8	1.9	1.0	1.3	1.8	2.0	1.9	1.5
Chest pain or discomfort	2.0	2.8	5.6	2.4	1.7	1.6	2.3	1.8	0.8	2.1	0.7	1.6	1.6	1.6	-1.2	1.5	1.6	0.9	1.6	2.1	1.9	1.5	1.7	1.6	1.9	1.6	2.0
Pack years of smoking	2.0	2.9	5.6	-1.7	-1.8	-1.6	-1.8	-2.0	-2.0	-1.8	-1.8	-1.7	-1.6	-1.7	1.1	-1.7	-1.2	-1.3	-1.7	-2.4	-1.6	-1.4	-1.8	-1.6	-1.5	-1.6	-2.3
Ulcerative Colitis (UC)	1.9	3.5	18.7	1.0	0.4	0.4	1.1	0.6	-0.2	0.7	0.6	0.4	0.2	0.3	0.1	0.4	2.2	0.9	4.1	2.9	2.8	0.3	3.3	0.8	2.6	4.3	2.0
Had major operations	1.9	2.3	4.2	1.3	2.0	1.9	1.4	1.8	2.1	1.8	1.3	1.9	1.9	2.0	-2.0	2.0	1.3	1.3	-0.3	1.0	0.4	1.1	0.7	1.9	1.0	-0.2	0.9
Eye problems/disorders: Cataract	1.9	2.2	9.9	0.6	1.0	0.9	0.4	1.2	2.1	0.3	1.3	1.0	1.0	1.1	-2.3	1.2	-1.2	-2.3	-3.1	-0.8	-1.0	-0.2	-2.1	1.7	0.5	-2.3	-1.8
Systolic blood pressure, automated reading	1.8	5.1	8.6	-2.4	-2.5	-2.4	-2.0	-2.5	-2.5	-2.6	-2.1	-2.5	-2.4	-2.5	2.9	-2.4	-1.4	-1.4	-0.9	-2.6	-2.3	-2.3	-1.6	-2.8	-2.8	-0.8	-2.0
Medication: Ibuprofen (e.g. Nurofen)	1.8	2.2	4.0	1.1	2.0	1.7	2.0	1.9	1.6	1.8	1.5	1.9	1.9	2.0	-1.5	2.0	1.6	0.1	0.2	0.9	1.0	1.4	1.0	1.5	1.2	-0.2	1.3
Birth weight of first child	1.8	3.3	8.8	-3.0	-2.2	-1.8	-2.7	-2.3	-2.1	-2.1	-2.1	-2.0	-1.9	-2.2	2.1	-2.3	-1.0	-0.3	0.0	-1.4	-0.9	-1.2	-1.0	-2.1	-1.4	-0.3	-1.4
Medication: Omeprazole	1.8	2.2	11.8	0.1	0.8	0.8	0.9	0.6	1.3	0.3	0.5	0.7	0.8	0.8	-1.2	0.7	-2.3	1.0	-3.2	-1.3	-1.6	1.2	-2.7	0.3	-1.6	-3.4	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	3.2	1.1	1.7	1.7	1.5	1.7	1.5	1.3	1.8	1.7	1.8	1.8	-1.8	1.6	0.8	1.7	-0.3	1.2	1.0	1.7	0.1	1.7	1.1	0.4	1.3
Illnesses of father: High blood pressure	1.8	2.3	4.8	-0.2	-1.6	-1.6	-0.5	-1.4	-1.6	-1.8	-1.1	-1.6	-1.7	-1.6	1.0	-1.5	-1.1	-1.0	-1.8	-2.0	-1.5	-1.4	-2.2	-1.4	-1.4	-1.2	-2.0
Heel T-Score	1.7	13.1	22.7	-3.5	-4.2	-4.1	-3.6	-4.0	-3.1	-4.8	-3.5	-4.2	-4.3	-4.2	3.1	-4.0	-2.5	-3.5	-2.2	-4.0	-3.0	-3.6	-3.2	-3.8	-3.0	-2.0	-4.3
Trunk fat percentage	1.7	6.9	12.8	2.9	2.7	3.0	3.0	2.7	2.2	3.6	2.2	2.8	3.0	2.7	-3.3	2.7	2.8	2.0	0.8	2.8	1.8	2.4	2.6	3.1	2.5	0.9	2.5
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.6	5.3	-2.3	-1.6	-1.5	-1.4	-1.8	-1.8	-2.2	-2.2	-1.5	-1.5	-1.5	1.4	-1.5	-0.7	-0.1	-1.0	-2.0	-1.9	-1.7	-1.4	-1.8	-2.1	-0.4	-1.3
Medication for pain relief, constipation, heartburn	1.7	3.0	4.8	-1.4	-2.2	-2.2	-2.1	-2.1	-1.9	-1.9	-1.8	-2.2	-2.2	-2.1	2.1	-2.1	-1.6	-1.0	0.3	-1.4	-0.8	-1.5	-0.9	-2.1	-1.3	-0.5	-1.6
Alcohol drinker status: Never	1.7	2.0	3.8	1.2	1.6	1.5	1.1	1.5	1.7	1.9	1.8	1.6	1.7	1.6	-1.5	1.6	1.4	-0.1	0.2	1.2	1.4	1.4	1.4	1.9	1.8	0.2	1.0
Type 2 Diabetes (T2D) (2012)	1.6	1.8	4.1	0.7	1.6	1.5	0.7	1.4	2.0	1.1	1.6	1.5	1.5	1.6	-1.2	1.6	2.0	0.4	0.9	1.1	1.3	0.9	1.4	1.4	1.6	1.0	1.1
Depression (self-reported)	1.6	1.9	4.8	-1.3	-1.1	-1.3	-1.2	-1.1	-0.6	-1.1	-1.5	-1.1	-1.2	-1.1	1.4	-0.9	-1.4	-1.6	-1.1	-2.0	-1.5	-1.0	-1.4	-1.5	-1.7	-2.2	-1.6
Pack years adult smoking proportion	1.5	2.3	4.6	-2.0	-1.6	-1.4	-1.7	-1.8	-1.8	-1.7	-1.6	-1.5	-1.4	-1.5	0.9	-1.5	-1.0	-1.2	-1.5	-2.1	-1.1	-1.1	-1.7	-1.3	-1.1	-1.5	-2.1
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.5	5.5	-1.9	-2.1	-2.0	-2.0	-1.9	-2.1	-2.3	-2.1	-2.1	-2.1	-2.1	1.6	-2.0	-0.8	-1.1	-0.7	-2.0	-2.1	-2.3	-1.0	-2.1	-2.2	-0.2	-1.7
High blood pressure	1.5	4.2	9.6	-1.3	-1.9	-1.8	-0.8	-1.9	-1.5	-1.4	-2.1	-1.9	-1.9	-1.9	1.1	-1.8	-2.3	-1.1	-3.1	-2.8	-3.1	-2.0	-2.4	-1.7	-2.8	-2.2	-2.5
Number of live births	1.5	2.1	3.9	0.3	1.6	1.9	1.7	1.6	0.7	1.3	1.5	1.7	1.8	1.6	-0.9	1.6	1.5	0.6	1.0	1.4	1.9	2.0	1.3	1.4	1.5	0.2	1.7
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.7	4.1	1.1	1.7	1.6	1.6	1.6	2.0	1.4	1.4	1.6	1.6	1.6	-1.8	1.7	1.3	-0.6	-0.4	0.5	0.4	0.8	0.7	1.4	0.7	-0.4	0.8
Medication: Lansoprazole	1.5	1.7	2.8	1.6	1.4	1.4	1.7	1.5	1.2	0.9	1.4	1.4	1.5	1.4	-1.5	1.3	1.5	1.5	0.6	1.2	0.9	1.1	0.9	1.4	1.1	0.9	1.2
Medication: Ventolin 100micrograms inhaler	1.5	1.9	5.6	0.5	1.2	1.2	0.6	1.4	1.1	0.6	0.7	1.1	1.1	1.3	-0.6	1.3	2.0	0.6	2.2	1.7	1.9	0.8	2.0	1.1	1.8	2.4	1.6
Supplements: Zinc	1.4	1.6	4.4	-1.7	-1.0	-1.1	-1.0	-1.2	-0.2	-1.2	-1.8	-1.1	-1.2	-1.0	1.1	-1.1	-1.0	0.6	-1.1	-1.6	-1.9	-1.0	-1.3	-1.5	-2.1	-0.9	-0.8
Weight	1.4	6.7	11.0	-2.8	-3.2	-3.1	-3.3	-3.3	-2.8	-2.7	-3.0	-3.2	-3.1	-3.1	2.5	-2.9	-0.9	-1.4	-0.2	-2.3	-2.3	-3.0	-0.6	-3.0	-2.2	0.0	-2.4
Mouth/teeth dental problems: Dentures	1.4	2.3	8.6	2.9	1.7	1.8	1.6	1.6	0.8	1.5	0.8	1.7	1.7	1.8	-1.5	1.8	1.5	0.9	0.4	1.4	1.0	1.1	1.4	1.9	1.6	0.9	1.2
Peak expiratory flow (PEF)	1.4	3.3	10.1	-1.8	-2.0	-1.9	-3.2	-2.1	-2.3	-3.0	-1.8	-1.8	-1.8	-1.8	2.0	-1.8	-0.7	-0.2	0.0	-2.1	-0.8	-1.3	-1.4	-2.3	-1.5	-0.6	-1.7
Pulse wave reflection index	1.4	1.8	4.4	0.5	1.7	1.6	2.0	1.7	1.9	1.5	1.6	1.5	1.5	1.6	-2.1	1.6	-0.0	-0.1	-1.1	0.5	-0.6	0.9	0.2	1.4	0.1	-1.6	0.6
Emphysema/chronic bronchitis	1.4	1.6	3.4	0.5	1.6	1.4	1.3	1.6	0.9	1.6	1.1	1.5	1.4	1.4	-1.8	1.4	0.5	1.5	0.3	1.6	0.6	1.1	0.8	1.6	1.0	0.8	1.3
Smoking status: Current	1.4	2.3	4.4	-1.3	-1.4	-1.1	-1.7	-1.6	-1.7	-1.5	-1.6	-1.3	-1.1	-1.3	0.8	-1.1	-1.4	-0.5	-1.9	-1.9	-2.0	-1.6	-2.1	-1.1	-1.6	-1.2	-2.0
Alzheimer’s Disease (in mother)	1.3	1.5	3.4	1.2	1.4	1.3	1.4	1.4	0.7	1.8	1.0	1.3	1.3	1.2	-1.8	1.2	0.9	0.9	0.6	1.5	0.9	1.2	1.2	1.4	1.2	0.2	1.3
Body Mass Index (BMI) (2010)	1.3	1.7	4.2	-2.0	-1.7	-1.6	-1.5	-1.4	-1.7	-1.2	-1.0	-1.7	-1.7	-1.6	1.9	-1.7	0.0	0.5	1.4	0.1	-0.1	-0.9	0.4	-1.4	-0.3	1.4	-0.2
Prospective memory result	1.3	1.6	9.5	0.3	-0.1	-0.4	0.2	-0.0	-1.2	0.2	-0.0	-0.2	-0.3	-0.1	0.8	0.0	1.6	0.8	3.1	1.6	1.7	0.0	2.5	-0.0	1.4	2.8	1.2
Hypertension (Self-reported)	1.3	3.7	8.0	-1.5	-1.8	-1.8	-0.6	-1.9	-1.5	-1.3	-2.2	-1.9	-1.8	-1.8	1.1	-1.7	-2.2	-0.8	-2.7	-2.5	-2.8	-1.8	-2.1	-1.7	-2.6	-1.8	-2.1
Long-standing illness, disability or infirmity	1.3	2.0	5.0	1.7	1.7	1.7	2.2	1.6	1.0	1.8	1.1	1.7	1.7	1.8	-2.1	1.7	0.1	1.7	-1.1	0.9	-0.2	1.3	0.0	1.7	0.2	-0.5	1.1
Illnesses of father: None of the above (group 1)	1.3	1.6	3.0	-1.0	1.5	1.4	0.5	1.4	1.3	1.2	1.7	1.4	1.4	1.5	-0.7	1.6	1.5	0.5	1.2	1.0	1.1	1.3	1.7	0.9	0.8	0.1	1.6
Ulcerative Colitis	1.2	1.8	8.5	0.4	0.5	0.3	1.4	0.6	-0.1	0.4	0.9	0.3	0.1	0.4	0.2	0.4	1.9	0.6	2.9	1.9	2.0	0.4	2.4	0.4	1.7	2.8	1.5
Multivitamins +/- minerals	1.2	1.6	7.2	-0.6	-0.6	-0.6	-0.3	-0.5	0.2	-1.1	-0.1	-0.6	-0.7	-0.5	-0.4	-0.5	-1.6	-0.6	-2.7	-1.7	-2.1	-0.9	-2.4	-0.4	-1.4	-2.0	-1.8
Stomach or abdominal pain in last month	1.2	1.5	4.2	-0.9	-1.4	-1.3	-1.6	-1.2	-2.0	-2.0	-1.1	-1.3	-1.3	-1.4	1.1	-1.5	-0.9	0.4	-0.5	-1.0	-1.1	-1.2	-1.3	-1.3	-1.1	-0.0	-1.1
Exposure to tobacco smoke outside home	1.2	1.6	5.8	0.9	1.5	1.3	0.9	1.4	2.4	0.8	0.9	1.4	1.2	1.6	-2.0	1.6	0.1	-0.4	-1.8	-0.3	0.1	1.3	-0.7	1.2	0.4	-1.9	0.0
Pulse rate, automated reading	1.2	3.7	14.7	0.5	-1.6	-1.2	-2.5	-1.6	-2.4	-1.5	-3.5	-1.4	-1.3	-1.5	2.1	-1.7	-0.1	3.4	2.8	1.2	2.2	0.2	0.3	-1.0	1.1	3.8	0.7
Wears glasses or contact lenses	1.2	1.4	4.1	-1.2	-0.8	-1.0	-1.3	-0.8	-1.1	-1.3	-1.1	-0.9	-1.2	-0.8	1.4	-0.7	-1.0	-0.6	-1.2	-1.4	-2.0	-1.4	-1.3	-1.0	-1.7	-0.8	-1.1
Ovarian Cancer	1.1	1.5	3.5	1.0	1.3	1.5	1.1	1.2	1.7	1.9	0.9	1.4	1.4	1.4	-1.5	1.4	0.2	1.0	-0.5	1.2	0.9	1.4	0.4	1.6	1.1	-0.2	1.0
Relative age of first facial hair	1.1	2.2	5.3	-0.0	1.6	1.5	1.1	1.6	1.1	0.7	1.9	1.6	1.6	1.6	-0.8	1.7	2.3	0.1	1.5	1.1	2.2	1.3	1.4	1.4	2.0	1.3	1.2
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	4.5	1.6	1.1	1.4	0.9	1.0	0.6	1.2	1.4	1.2	1.5	1.0	-2.1	1.0	1.2	0.4	-0.5	0.7	0.5	0.7	0.5	1.7	1.5	-0.3	0.2
Chronic bronchitis/emphysema (father)	1.1	1.3	5.0	1.5	0.9	0.9	0.9	1.0	0.1	1.1	-0.3	0.8	0.9	0.9	-0.7	0.9	0.3	2.2	1.5	1.9	1.0	1.2	1.1	0.7	0.6	1.4	1.9
Forced vital capacity (FVC)	1.1	4.2	13.9	-1.8	-2.3	-2.3	-3.7	-2.3	-1.9	-3.7	-1.7	-2.2	-2.3	-2.1	2.1	-2.1	-1.4	-0.8	-0.4	-2.2	-0.7	-1.4	-2.0	-2.3	-1.3	-0.3	-2.1
Alcohol intake versus 10 years previously	1.1	1.6	4.1	0.5	1.6	1.5	1.2	1.5	0.7	1.6	0.5	1.5	1.5	1.6	-1.4	1.7	-1.0	2.0	-1.2	0.7	-0.5	1.5	-0.6	1.2	-0.6	-1.0	1.4
Breastfed as a baby	1.1	1.4	2.7	0.9	1.4	1.6	1.0	1.3	1.5	1.3	1.2	1.4	1.6	1.4	-1.2	1.1	1.2	-0.2	0.4	1.2	1.0	1.1	0.8	1.4	1.3	0.1	1.1
Medication: Paracetamol	1.1	1.9	3.4	0.2	1.6	1.8	1.7	1.6	0.9	1.4	1.6	1.7	1.8	1.6	-1.8	1.5	1.1	1.1	-0.3	1.1	0.9	1.5	0.6	1.7	1.1	0.4	1.4
Medication: Amlodipine	1.1	1.5	3.8	-0.1	-1.2	-1.1	-0.9	-1.2	-0.8	-1.3	-1.2	-1.1	-1.0	-1.1	0.9	-1.1	-1.4	-0.7	-1.8	-1.8	-1.0	-0.5	-1.9	-1.1	-1.2	-1.9	-1.6
Eye problems/disorders: None of the above	1.1	1.2	4.9	-0.5	-1.0	-0.9	-1.3	-1.1	-1.3	-1.3	-1.0	-0.9	-0.9	-0.9	2.0	-1.1	0.8	0.3	2.2	-0.0	0.8	-0.4	0.9	-1.5	-0.3	1.6	0.5
Supplements: Vitamin C	1.1	1.3	4.0	-0.7	-1.1	-1.2	-1.1	-1.1	-0.3	-2.0	-1.1	-1.1	-1.0	-1.0	1.8	-1.3	-0.9	-0.7	-0.6	-1.4	-0.9	-1.0	-1.6	-1.3	-1.2	-0.2	-1.0
Handedness (chirality/laterality): Left-handed	1.1	1.3	2.9	1.0	1.4	1.3	1.0	1.4	0.5	1.7	0.5	1.2	1.0	1.4	-1.2	1.4	0.4	1.6	0.8	1.5	0.7	1.1	1.2	1.2	0.8	0.7	1.7
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	6.0	0.2	0.9	0.8	0.9	0.6	1.2	0.5	0.7	0.8	0.7	0.8	-1.2	0.7	-1.5	1.5	-2.4	-0.8	-1.2	1.1	-2.1	0.4	-1.1	-2.5	-0.2
Leg fat mass (left)	1.1	4.1	7.0	-2.1	-2.6	-2.4	-2.0	-2.6	-2.6	-1.8	-2.5	-2.6	-2.4	-2.6	1.8	-2.3	-0.2	-1.2	-0.2	-1.7	-1.9	-2.6	-0.1	-2.3	-1.7	-0.1	-2.0
Alzheimer’s Disease (in father)	1.0	1.1	2.9	0.1	-1.3	-1.2	-1.3	-1.4	-0.7	-1.7	-1.5	-1.3	-1.4	-1.3	1.3	-1.2	0.4	0.0	0.6	-0.5	0.2	-1.1	-0.1	-1.1	0.0	1.3	-0.7
Age at First Birth	1.0	1.4	4.3	0.8	1.4	1.3	1.6	1.2	2.1	1.6	1.5	1.3	1.3	1.3	-1.7	1.5	0.2	-0.5	-0.9	0.4	0.2	1.0	-0.1	1.3	0.5	-1.1	0.5
Smoking Status	1.0	2.3	4.2	-1.9	-1.4	-1.4	-1.3	-1.4	-2.0	-2.0	-1.3	-1.4	-1.4	-1.4	1.5	-1.3	-1.4	-0.8	-1.4	-1.8	-1.7	-1.5	-2.0	-1.4	-1.6	-0.7	-1.7
Medication for hormone replacement therapy	1.0	1.1	2.1	0.8	1.2	1.2	0.3	1.3	0.6	0.7	1.2	1.3	1.3	1.3	-1.0	1.4	1.1	0.6	0.3	0.7	1.4	1.4	0.5	1.1	1.4	0.0	0.8
Severe depression (siblings)	1.0	1.1	2.4	-0.4	-0.9	-0.8	-1.0	-1.1	-0.8	-0.9	-1.2	-0.9	-0.9	-1.0	1.4	-0.8	-1.1	-0.2	-1.1	-1.4	-1.1	-0.6	-1.3	-1.2	-1.6	-1.4	-0.9
Pulse rate	1.0	1.8	10.5	0.9	-0.6	-0.6	-0.9	-0.6	-1.6	-0.6	-1.8	-0.5	-0.7	-0.6	1.4	-0.7	0.9	1.8	2.5	1.1	1.9	0.2	1.1	-0.5	1.0	3.2	1.1
Exposure to tobacco smoke at home	1.0	1.2	2.7	-0.2	1.4	0.9	1.3	1.3	0.8	1.5	0.6	1.2	1.0	1.4	-1.0	1.5	0.6	1.6	0.5	1.1	0.2	1.2	1.3	1.0	0.3	-0.0	1.5
Hair/balding pattern: Pattern 4	1.0	2.5	4.3	2.0	1.8	1.8	2.1	1.9	1.6	1.2	1.7	1.9	1.7	1.9	-1.6	1.9	1.3	-0.7	0.5	1.4	1.4	1.3	1.0	1.9	1.8	0.6	1.3
Glaucoma (self-reported)	1.0	1.1	3.5	-1.9	-1.0	-1.1	-0.6	-1.1	-1.1	-0.1	-1.3	-1.0	-1.1	-1.1	1.4	-0.9	-1.0	1.2	0.3	-0.9	-1.0	-0.5	-0.2	-1.7	-1.8	-0.5	-0.1
Leg fat mass (right)	1.0	4.0	6.8	-2.2	-2.6	-2.4	-2.0	-2.6	-2.4	-1.8	-2.6	-2.5	-2.4	-2.5	1.7	-2.3	-0.3	-1.1	-0.2	-1.7	-1.9	-2.5	-0.2	-2.2	-1.8	-0.1	-1.9
Mouth/teeth dental problems: Mouth ulcers	1.0	1.7	5.2	1.3	1.5	1.4	2.2	1.5	0.9	2.3	1.0	1.3	1.3	1.3	-1.6	1.3	-0.2	1.1	-0.2	1.0	0.5	1.9	0.4	1.1	0.2	-1.2	1.4
Ever taken oral contraceptive pill	1.0	1.1	3.2	-1.0	-1.0	-1.1	-1.6	-0.9	-1.1	-1.4	-1.8	-1.1	-1.2	-1.0	1.7	-1.0	-0.2	0.3	1.4	-0.1	0.8	-0.3	0.0	-1.2	0.0	1.1	-0.2
Irritability	1.0	1.7	4.4	0.4	1.5	1.3	0.8	1.5	0.8	0.6	0.9	1.4	1.4	1.6	-1.4	1.5	2.1	-0.2	1.4	1.3	1.4	0.4	1.7	1.5	1.9	1.4	0.9
Average weekly spirits intake	0.9	1.1	3.2	-1.2	-1.3	-1.3	-1.1	-1.2	-0.8	-1.2	-1.0	-1.3	-1.3	-1.3	1.8	-1.3	0.0	-0.1	1.0	-0.6	-0.4	-0.6	0.5	-1.6	-0.9	-0.2	-0.4
Vitamin and mineral supplements	0.9	1.3	5.1	1.1	0.6	0.6	0.9	0.5	-0.4	1.6	0.1	0.5	0.5	0.4	-0.4	0.6	1.1	1.0	2.0	1.7	1.5	0.8	2.3	0.6	1.3	1.3	1.5
Current tobacco smoking	0.9	1.5	3.3	-0.9	-1.1	-0.9	-1.4	-1.2	-1.2	-1.2	-1.3	-0.9	-0.8	-1.0	0.6	-0.7	-1.1	-0.6	-1.6	-1.6	-1.6	-1.4	-1.8	-0.8	-1.2	-1.0	-1.8
Taking other prescription medications	0.9	1.4	2.9	1.7	1.5	1.5	1.2	1.6	0.8	1.0	0.9	1.5	1.4	1.5	-1.3	1.6	-0.0	1.7	-1.0	0.4	-0.4	1.2	-0.7	1.1	-0.3	-0.8	0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	3.4	-1.5	-1.6	-1.6	-1.3	-1.4	-1.7	-1.9	-1.8	-1.7	-1.7	-1.6	0.9	-1.6	-1.3	-0.9	-1.2	-1.6	-1.3	-1.0	-1.4	-1.5	-1.5	-0.8	-1.3
Financial difficulties in last 2 years	0.9	1.3	3.8	-1.2	-0.5	-0.5	-0.7	-0.7	-0.1	-1.1	-1.2	-0.6	-0.7	-0.5	0.6	-0.5	-1.3	0.2	-1.9	-1.7	-1.7	-0.5	-1.8	-1.0	-1.9	-1.6	-0.9
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.1	-1.0	-1.4	-1.3	-1.8	-1.3	-1.7	-1.2	-1.4	-1.3	-1.4	-1.3	1.3	-1.4	-0.1	-0.2	0.2	-0.8	-0.2	-0.8	-0.3	-1.4	-0.7	0.0	-0.8
Headache pain in last month	0.9	1.6	3.0	1.1	1.5	1.6	1.2	1.7	1.0	1.2	1.3	1.5	1.6	1.6	-1.3	1.7	0.7	1.0	0.0	1.0	1.1	1.6	0.3	1.4	1.1	-0.0	1.3
High blood pressure (siblings)	0.9	1.2	2.9	-0.7	-1.3	-1.1	-0.8	-1.2	-0.6	-1.1	-1.0	-1.2	-1.1	-1.3	0.9	-1.4	-1.7	-0.1	-1.0	-1.2	-1.0	-0.6	-1.4	-1.1	-1.2	-1.1	-1.2
Cholesterol lowering medication	0.9	1.4	4.0	0.2	1.0	1.0	2.0	1.1	0.9	1.3	0.7	1.0	1.3	0.9	-1.3	0.9	1.3	-0.1	1.1	1.5	1.4	0.7	1.5	1.3	1.5	1.5	1.0
Mean Putamen Volume	0.8	1.0	3.6	0.9	0.5	0.7	0.8	0.4	0.6	1.1	0.1	0.5	0.7	0.5	0.1	0.5	1.9	1.1	1.6	1.0	0.7	0.5	1.9	0.0	0.0	1.5	1.7
Qualifications: CSEs or equivalent	0.8	1.1	3.9	-1.2	-1.1	-1.0	-0.6	-1.1	-2.0	-0.6	-0.4	-1.2	-1.2	-1.2	1.3	-1.1	0.6	0.2	1.7	0.0	0.4	-1.0	1.1	-1.1	-0.1	1.6	-0.1
Waist circumference	0.8	3.0	5.8	-1.5	-2.1	-1.9	-1.4	-2.2	-2.1	-1.3	-1.8	-2.1	-2.0	-2.1	1.3	-1.9	-0.5	-1.1	-0.7	-1.7	-2.4	-2.4	-0.2	-1.9	-2.0	-0.6	-1.8
Heart attack	0.8	1.0	5.2	-0.4	1.0	1.0	0.8	0.9	0.4	0.8	1.7	1.0	1.0	1.1	-2.3	1.1	0.6	-0.5	-1.7	-0.0	-0.7	-0.3	-0.2	1.6	0.7	-0.3	-0.5
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	10.4	-1.5	-1.8	-1.7	-3.2	-1.8	-1.3	-3.2	-1.0	-1.6	-1.8	-1.6	1.5	-1.5	-1.1	-0.5	-0.7	-1.9	-0.7	-1.1	-1.9	-1.8	-1.0	-0.5	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	5.3	-1.2	-0.7	-0.6	-1.1	-0.6	-1.7	-1.2	-0.9	-0.6	-0.4	-0.5	0.7	-0.5	-1.5	0.7	-1.5	-1.4	-1.2	-0.3	-2.3	-0.9	-1.5	-1.5	-1.0
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	8.8	0.6	-0.8	-0.3	-0.2	-0.6	-0.6	-0.8	0.1	-0.6	-0.4	-0.7	-0.8	-0.9	-1.5	-1.3	-3.0	-1.4	-2.0	-1.2	-2.3	0.0	-1.1	-1.7	-2.0
Chronic bronchitis/emphysema (mother)	0.8	1.0	4.0	-0.9	-0.4	-0.3	-0.9	-0.7	-0.7	-0.0	-0.7	-0.4	-0.2	-0.4	0.2	-0.3	-1.3	-1.1	-1.5	-1.5	-1.7	-0.7	-0.8	-0.7	-1.7	-2.0	-0.9
Forced vital capacity (FVC), Best measure	0.8	2.8	11.1	-1.2	-1.9	-1.9	-3.3	-1.8	-1.5	-3.3	-1.2	-1.8	-1.9	-1.6	1.9	-1.6	-1.1	-0.5	-0.1	-1.7	-0.1	-0.9	-1.6	-1.9	-0.8	-0.1	-1.6
Medication: Blood pressure	0.8	1.3	5.5	-0.1	-0.7	-0.8	-0.3	-0.7	-0.3	-0.7	-0.5	-0.8	-0.9	-0.7	-0.1	-0.7	-1.1	-1.8	-2.3	-1.8	-1.2	-0.7	-1.6	-0.4	-0.8	-2.1	-1.9
Medication: Ibuprofen	0.8	0.9	2.0	0.8	1.2	1.2	1.3	1.2	1.1	0.9	1.0	1.2	1.2	1.2	-1.0	1.4	1.4	-0.3	0.1	0.4	0.3	0.4	0.7	1.0	0.6	0.2	0.7
Illnesses of father: Heart disease	0.8	1.1	2.9	-0.0	-0.9	-1.1	-0.2	-0.9	-0.9	-0.7	-0.9	-1.1	-1.1	-1.0	0.6	-1.1	-1.4	-1.7	-1.3	-1.1	-1.2	-1.1	-1.3	-0.7	-0.9	-1.1	-1.5
Mother’s age at death	0.8	0.9	8.7	1.1	0.0	-0.0	0.9	-0.0	0.3	0.5	0.2	0.0	0.0	-0.0	-0.2	-0.3	-1.6	-0.3	-1.9	-0.9	-0.7	0.8	-1.5	-0.2	-0.8	-2.9	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	5.2	-0.4	-0.5	-0.5	0.5	-0.6	-0.4	-0.9	-0.2	-0.5	-0.4	-0.4	-0.7	-0.6	-1.3	-1.1	-2.3	-1.2	-1.0	-0.6	-1.9	0.1	-0.4	-1.8	-1.7
Verbal and Numeric Reasoning (VNR)	0.7	1.6	5.9	0.2	-0.8	-1.0	-0.2	-0.9	-0.0	-0.3	-0.8	-0.9	-1.1	-0.9	-0.7	-0.9	-1.8	-1.9	-2.4	-1.4	-2.2	-1.5	-1.5	-0.2	-1.0	-1.8	-2.0
Fasting Glucose	0.7	0.9	2.1	-1.2	-1.1	-1.1	-1.1	-1.0	-1.2	-1.0	-0.7	-1.1	-1.1	-1.2	0.8	-1.5	-0.0	-1.1	0.3	-0.6	-0.6	-1.3	0.1	-0.8	-0.2	0.2	-1.0
Respiratory disease	0.7	1.5	3.8	1.7	1.2	0.7	0.4	1.3	1.0	0.8	0.5	1.0	0.7	1.2	-0.5	1.3	1.7	0.9	1.7	1.5	1.0	0.8	1.9	0.9	1.1	1.6	1.6
Average weekly fortified wine intake	0.7	0.8	3.7	1.9	0.7	0.6	0.9	0.9	-0.1	1.2	0.3	0.7	0.7	0.7	-0.5	0.6	1.3	-0.8	0.8	1.0	0.4	0.2	1.7	0.8	0.7	0.5	1.0
Medication: Atenolol	0.7	0.9	2.5	-0.8	-1.2	-1.1	-1.0	-1.1	-0.6	-0.5	-0.4	-1.2	-1.2	-1.3	0.8	-1.1	-0.6	-1.0	-0.4	-0.7	-1.2	-1.6	-0.0	-0.7	-0.6	0.2	-1.1
Medication: Levothyroxine sodium	0.7	1.2	7.3	2.2	0.3	0.7	0.8	0.3	0.1	-0.0	0.5	0.4	0.6	0.3	-1.8	0.2	-0.9	-0.2	-2.7	-0.8	-1.4	-0.3	-1.9	0.8	-0.6	-1.4	-1.1
Hair/balding pattern: Pattern 2	0.7	0.9	2.2	0.5	1.1	0.7	1.1	0.9	0.8	1.5	0.4	0.9	1.0	0.8	-1.4	0.9	-1.0	1.2	-1.5	0.3	-0.7	0.6	-0.7	0.9	-0.4	-1.4	0.3
Had menopause	0.7	0.9	6.5	2.5	0.2	0.5	0.7	0.3	0.3	0.6	0.5	0.4	0.6	0.1	-0.0	0.2	1.4	-0.2	1.4	1.3	0.2	-0.5	1.9	0.7	0.8	1.7	0.7
Fluid intelligence score	0.7	1.5	4.7	0.4	-0.9	-1.0	-0.7	-1.0	-0.2	-0.5	-0.7	-1.1	-1.1	-1.0	-0.5	-1.1	-1.4	-2.2	-2.1	-1.2	-1.9	-1.6	-1.3	-0.3	-0.8	-1.4	-1.9
Lung cancer (father)	0.7	0.8	2.5	0.5	0.8	0.7	0.2	0.9	1.3	0.3	0.8	0.9	0.8	0.9	-0.7	1.0	0.9	0.1	1.1	1.2	0.5	-0.1	1.1	0.9	0.9	1.6	0.9
Gout (self-reported)	0.7	0.9	5.0	0.3	-0.3	-0.5	-0.1	-0.3	0.1	0.1	0.0	-0.4	-0.4	-0.4	-0.8	-0.3	-1.3	-0.4	-2.2	-0.9	-2.0	-0.8	-1.3	0.1	-1.0	-1.9	-1.4
Body fat percentage	0.7	2.8	5.8	1.8	1.6	1.9	2.1	1.6	1.2	2.4	1.2	1.7	2.0	1.7	-2.3	1.7	2.2	1.3	0.4	1.8	0.9	1.4	2.0	2.0	1.5	0.5	1.5
Number of children fathered	0.7	0.7	3.6	-1.9	-0.8	-0.6	-0.7	-0.8	-0.8	-0.7	-0.4	-0.7	-0.7	-0.7	1.2	-0.9	0.9	-1.2	0.4	-0.9	-0.7	-1.0	0.3	-1.1	-0.9	-0.2	-0.5
Health satisfaction	0.7	0.9	5.5	-0.0	0.7	0.7	1.2	0.7	0.5	0.5	0.6	0.7	0.8	0.6	-0.8	0.8	-0.6	-1.0	-2.0	-0.9	-0.9	0.4	-1.2	0.4	-0.8	-2.3	-0.5
Commuting to job workplace: Walk	0.7	0.7	2.5	0.5	0.9	0.9	1.2	0.6	1.2	1.6	1.3	0.8	0.9	0.8	-1.4	0.7	0.1	-0.3	-0.5	0.6	-0.0	0.4	0.8	1.1	0.6	-0.5	0.4
Mineral and other dietary supplements	0.7	0.9	3.6	0.5	0.9	0.9	1.0	1.0	0.1	1.9	0.8	1.0	1.0	0.8	-1.1	0.8	0.2	0.8	0.5	1.1	1.0	1.4	1.0	0.9	0.8	-0.6	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	2.7	-0.1	-1.1	-1.3	-0.9	-1.2	-0.6	-1.6	-0.9	-1.2	-1.3	-1.1	1.4	-1.1	-1.5	-0.6	-0.7	-1.5	-1.2	-0.8	-1.5	-1.5	-1.6	-1.1	-1.1
Medication: Lisinopril	0.7	0.9	2.2	-0.1	-1.3	-1.4	-0.4	-1.0	-0.8	-1.2	-1.0	-1.4	-1.5	-1.3	0.8	-1.3	-0.8	-0.7	0.1	-0.6	-0.5	-1.1	-0.4	-1.1	-0.6	0.4	-0.9
Age started oral contraceptive pill	0.7	0.9	2.8	0.0	-0.8	-1.1	-0.5	-0.6	0.6	-0.7	-0.9	-0.9	-0.9	-0.9	1.7	-0.8	0.8	-1.4	1.7	0.0	-0.1	-1.4	1.1	-0.9	-0.1	1.2	-0.2
Vascular/heart problems diagnosed by doctor	0.7	2.0	5.8	0.8	1.1	1.2	0.2	1.2	1.3	0.7	1.7	1.2	1.2	1.2	-0.4	1.1	1.4	0.7	2.4	1.9	2.4	1.5	1.6	1.0	1.9	1.6	1.8
Basal cell carcinoma (self-reported)	0.7	0.8	1.9	1.1	0.8	0.7	1.3	0.8	0.8	1.1	1.0	0.8	0.8	0.7	-0.4	0.7	0.5	0.6	1.2	1.4	0.9	0.6	1.2	0.8	1.0	1.1	1.1
Heart attack/myocardial infarction (self-reported)	0.7	1.0	4.9	-0.2	1.0	1.0	0.8	0.9	0.4	0.7	1.7	1.0	1.0	1.0	-2.2	1.0	0.8	-0.5	-1.5	0.0	-0.5	-0.2	-0.1	1.6	0.8	-0.2	-0.5
Heart disease (siblings)	0.7	0.8	2.8	-0.7	-0.9	-1.1	-0.1	-0.8	-1.7	-0.8	-1.1	-1.0	-1.0	-1.0	0.2	-0.9	-1.1	-0.2	-1.0	-0.8	-0.9	-0.7	-1.0	-0.7	-0.8	-0.6	-1.0
Depressed Affect (Nagel 2018)	0.6	1.3	3.7	0.2	1.1	1.3	1.9	1.2	-0.1	1.0	0.8	1.2	1.4	1.1	-1.5	1.4	0.9	1.2	0.4	1.5	0.7	0.7	0.7	1.5	1.2	1.1	1.0
Alzheimer’s Disease (including proxy)	0.6	0.8	2.6	1.6	0.7	0.7	0.8	0.6	-0.1	0.9	0.3	0.6	0.5	0.4	-1.1	0.7	1.3	0.5	0.9	1.2	1.1	0.5	1.2	0.9	1.4	1.0	0.7
Irritable Bowel Disease (IBD)	0.6	1.5	4.9	0.7	0.6	0.7	0.7	0.8	0.5	0.8	0.8	0.6	0.6	0.6	-0.3	0.6	1.5	0.5	2.2	1.8	2.2	0.8	1.9	0.9	2.0	2.2	1.3
HDL Cholesterol	0.6	1.0	3.8	1.9	0.9	0.9	0.9	1.0	0.5	0.9	0.8	0.9	1.0	0.9	-0.7	0.7	0.8	1.2	0.8	1.2	0.7	0.5	1.1	1.0	1.0	1.3	1.1
Hearing difficulty/problems: Yes	0.6	1.0	2.2	-0.1	1.4	1.4	1.3	1.4	0.1	0.4	0.8	1.5	1.5	1.5	-0.6	1.5	1.0	-0.0	0.1	0.2	1.0	1.2	0.2	1.0	0.7	-0.1	0.7
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	3.1	-0.1	0.8	1.0	1.7	0.7	0.1	1.7	0.2	0.7	0.8	0.7	-1.6	0.6	-0.3	1.2	-1.1	0.6	-0.2	1.0	-0.1	1.1	0.2	-1.0	0.3
Serious illness, injury or assault to yourself	0.6	0.7	2.2	0.0	0.9	1.0	0.6	0.9	0.9	0.6	0.4	0.9	0.9	0.9	-1.0	0.8	0.7	1.5	0.6	1.1	0.7	0.7	0.6	0.9	0.7	1.0	1.1
Arm fat percentage (right)	0.6	2.2	5.9	1.2	1.4	1.6	2.1	1.4	1.0	2.4	0.8	1.5	1.6	1.4	-1.9	1.5	1.7	1.3	0.6	1.6	0.8	1.3	1.8	1.6	1.2	0.6	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	8.9	-0.9	-1.5	-1.5	-2.8	-1.4	-1.0	-3.0	-0.7	-1.4	-1.6	-1.2	1.4	-1.2	-0.9	-0.5	-0.5	-1.6	-0.5	-0.9	-1.7	-1.5	-0.8	-0.3	-1.5
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	4.0	0.5	0.7	0.8	0.4	0.7	0.3	0.8	0.5	0.8	0.9	0.7	0.2	0.6	1.2	0.8	2.0	1.4	1.0	0.5	1.5	0.4	0.6	1.7	1.7
Commuting to job workplace: Car/motor vehicle	0.6	0.7	4.1	-0.6	0.7	0.7	-0.1	0.9	0.9	-0.1	0.5	0.7	0.7	0.7	-0.3	0.7	0.4	1.0	0.8	0.4	2.0	1.7	-0.1	0.4	1.1	0.3	0.7
Medication: Aspirin	0.6	0.8	3.1	-1.1	-0.9	-0.8	-0.9	-1.0	-0.7	-0.3	-0.9	-0.9	-0.9	-0.9	-0.1	-1.0	-0.5	-0.9	-1.3	-0.5	-1.7	-1.8	-0.4	-0.1	-0.5	0.2	-1.1
Illnesses of siblings: Diabetes	0.6	0.8	1.8	-1.0	-1.0	-1.0	-1.3	-1.0	-1.3	-1.1	-0.9	-1.0	-0.9	-1.0	0.9	-1.1	-0.1	0.2	0.4	-0.7	-0.6	-1.0	-0.2	-1.1	-0.8	0.2	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.9	0.7	0.8	0.9	1.4	0.9	0.6	0.9	0.8	0.8	0.9	0.7	-1.2	0.6	0.8	-0.4	0.3	1.1	0.4	0.3	0.9	1.1	1.0	0.6	0.6
Back pain experienced in last month	0.6	0.9	2.5	0.3	-0.8	-1.0	0.4	-0.6	-1.5	-1.3	-1.3	-0.9	-0.9	-0.8	0.9	-0.6	-1.5	0.6	-1.1	-0.6	-1.3	-0.5	-1.6	-0.8	-1.4	-0.2	-0.4
Unable to work because of sickness or disability	0.6	0.7	4.0	0.9	0.4	0.6	0.3	0.5	-0.1	1.0	0.6	0.5	0.6	0.4	-0.3	0.4	0.4	2.0	1.2	1.3	1.1	1.1	0.9	0.5	0.8	1.0	1.2
Commuting to job workplace: Cycle	0.6	0.7	3.2	1.8	1.2	0.9	1.3	1.1	1.2	0.5	0.1	1.0	0.9	1.1	-0.8	1.3	0.2	0.6	-0.3	0.3	-0.2	0.3	-0.0	0.8	0.1	0.0	0.6
Alcohol drinker status: Previous	0.6	0.6	1.7	-0.4	1.0	0.8	1.0	1.0	0.6	0.6	0.8	1.0	0.9	1.0	-1.3	0.8	0.0	0.9	-0.9	0.2	0.2	1.1	-0.5	0.9	0.4	-0.7	0.4
Neuroticism (Nagel 2018)	0.5	1.1	2.9	-0.1	1.0	1.1	1.7	1.0	-0.2	0.8	0.8	1.1	1.2	0.9	-1.2	1.1	1.5	0.6	0.8	1.3	1.0	0.6	1.2	1.2	1.3	1.2	1.0
Coronary Artery Disease (CAD)	0.5	0.6	2.5	-1.4	-0.5	-0.3	-0.3	-0.6	-1.3	-1.0	-0.5	-0.3	-0.2	-0.5	0.3	-0.3	-1.3	1.6	-0.6	-0.0	-0.3	0.1	-1.4	-0.2	-0.5	0.7	-0.1
Hypothyroidism (self reported)	0.5	1.2	5.0	0.1	-1.0	-0.5	-0.2	-0.8	-0.6	-0.6	-0.3	-0.8	-0.6	-1.0	-0.6	-1.2	-1.4	-1.4	-2.2	-1.1	-1.4	-1.0	-1.9	-0.1	-0.6	-1.3	-1.8
Medication: Co-codamol	0.5	0.5	1.8	0.6	0.8	0.7	0.4	0.8	0.9	0.6	0.1	0.7	0.6	0.8	-1.0	0.9	-1.2	-0.1	-1.3	0.3	-0.6	0.4	-0.8	0.9	-0.1	-0.8	0.2
Had other major operations	0.5	0.7	1.7	0.6	0.8	0.8	1.3	0.8	0.1	1.1	0.9	0.8	0.9	0.7	-1.3	0.5	-0.6	-0.1	-1.3	0.1	0.2	1.0	-0.7	1.0	0.5	-1.2	-0.1
Medication: Simvastatin	0.5	0.7	2.7	-0.2	0.9	0.9	1.7	1.0	0.8	1.0	0.8	0.9	1.0	0.9	-1.2	1.0	0.6	-0.3	-0.3	0.7	0.8	0.5	0.4	1.3	1.2	0.2	0.2
Hair/balding pattern: Pattern 3	0.5	0.8	3.4	-1.3	-1.0	-0.9	-1.6	-0.9	-1.2	-0.7	-0.5	-0.9	-0.9	-1.0	0.9	-1.0	-1.0	1.9	0.5	0.1	-0.3	-0.0	-0.3	-0.9	-0.5	0.3	0.1
Blood clot in the leg (DVT)	0.5	0.7	3.3	-0.1	-0.5	-0.5	0.5	-0.5	-0.4	-0.9	-0.3	-0.4	-0.4	-0.3	-0.6	-0.6	-0.9	-0.8	-1.8	-1.0	-0.9	-0.7	-1.5	0.0	-0.3	-1.3	-1.5
Number of full brothers	0.5	0.6	2.4	-1.5	-0.6	-0.7	-1.0	-0.4	0.1	-1.4	-0.0	-0.6	-0.6	-0.6	-0.2	-0.5	-0.2	-1.3	-0.5	-0.6	-0.1	-1.0	-0.8	0.1	0.7	0.0	-1.5
Medication: Seretide 50 evohaler	0.5	0.5	2.9	1.7	0.5	0.5	1.0	0.6	0.4	0.9	0.5	0.5	0.6	0.5	-0.9	0.4	-0.6	-0.7	-1.3	-0.1	-0.5	0.3	-0.2	0.8	-0.0	-1.2	-0.3
Myopia	0.5	0.8	2.1	0.5	1.1	1.4	0.1	0.9	0.8	0.9	1.3	1.3	1.4	1.3	-0.8	1.2	0.9	-0.3	0.2	0.4	0.4	0.2	0.6	1.1	0.8	0.4	0.5
Bipolar Disorder (2018)	0.4	0.6	1.7	-0.8	-0.9	-1.1	-1.0	-0.6	-0.7	-1.1	-0.2	-0.9	-1.0	-1.0	0.7	-0.7	0.1	-0.5	-0.2	-0.6	-0.8	-1.3	-0.4	-0.7	-0.4	0.2	-0.9
Major Depression (MDD)	0.4	0.4	2.3	-0.8	0.5	0.3	-0.3	0.7	-0.3	-0.0	1.0	0.4	0.3	0.6	-0.8	0.7	-0.7	-1.5	-0.9	0.0	0.1	0.2	-0.8	0.8	0.6	-0.7	-0.5
Reaction Time	0.4	0.7	2.3	-0.8	0.9	0.8	0.9	0.6	0.5	1.5	0.5	0.8	0.9	0.8	-0.6	0.8	0.3	1.5	0.2	0.6	0.3	1.3	0.7	0.4	-0.1	-0.6	1.4
Rheumatoid Arthritis	0.4	0.6	1.5	0.2	0.7	0.8	0.6	0.5	-0.3	0.8	0.6	0.8	0.8	0.7	-1.0	0.9	-1.1	0.5	-1.2	0.1	0.2	1.0	-1.2	0.7	0.1	-0.9	0.3
Sensitivity / hurt feelings	0.4	0.6	2.7	-1.1	-0.5	-0.2	-0.3	-0.5	-1.0	-0.8	-0.2	-0.3	-0.2	-0.4	-0.6	-0.4	-0.9	-0.5	-1.6	-0.8	-1.1	-0.5	-1.3	-0.0	-0.5	-1.2	-1.1
Ever used hormone-replacement therapy (HRT)	0.4	0.6	3.2	0.3	-0.6	-0.4	-0.2	-0.7	-1.0	-0.2	-0.3	-0.5	-0.3	-0.6	0.4	-0.6	0.2	-0.6	-0.6	-0.9	-1.8	-1.4	0.1	-0.6	-1.4	-0.5	-0.8
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	2.6	-0.7	-0.0	-0.3	-0.0	-0.1	0.4	0.3	-0.1	-0.2	-0.4	0.0	-0.5	-0.0	-1.6	1.1	-1.6	-0.3	-0.7	0.5	-1.2	0.2	-0.3	-1.0	-0.3
Nervous feelings	0.4	0.7	3.5	-0.6	0.1	0.1	0.9	0.1	-0.8	0.0	0.2	0.1	0.2	0.0	0.3	0.1	1.9	0.7	1.7	0.7	1.1	0.3	1.7	0.0	0.9	1.4	0.9
Length of working week for main job	0.4	0.4	2.1	0.4	0.0	-0.1	-0.9	0.1	0.4	-0.6	-0.4	-0.0	-0.1	0.1	-0.7	0.1	-1.3	-0.1	-1.5	-0.3	-0.5	0.0	-1.4	0.4	-0.1	-0.9	-0.7
Heart disease (mother)	0.4	0.5	3.0	1.7	0.6	0.6	1.1	0.6	1.0	0.6	0.9	0.6	0.6	0.6	-1.0	0.5	0.6	-0.4	-0.3	0.4	0.3	0.3	0.4	1.0	1.0	0.1	-0.0
Leg pain on walking	0.4	0.5	3.2	0.4	0.5	0.6	1.0	0.4	-0.8	0.2	-0.0	0.6	0.7	0.5	0.2	0.6	0.2	1.8	0.4	0.5	0.7	1.3	-0.2	0.2	0.1	0.2	0.9
Illness, injury, bereavement, stress in last 2 years	0.4	0.4	2.2	-0.1	-0.9	-0.8	-0.4	-0.9	-1.5	-0.0	-0.3	-1.0	-0.9	-0.9	0.6	-0.9	-0.7	-0.1	0.7	0.3	0.2	-0.4	0.2	-0.5	0.2	0.7	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	3.6	-1.2	-1.0	-1.0	-1.9	-1.1	-0.9	-1.4	-0.6	-1.0	-1.1	-0.9	0.8	-1.0	-0.7	0.5	0.1	-0.6	-0.7	-0.9	-0.5	-0.9	-0.6	0.3	-0.8
Arm fat percentage (left)	0.4	1.5	4.6	1.0	1.1	1.3	1.9	1.0	0.7	2.1	0.7	1.1	1.3	1.1	-1.8	1.1	1.4	1.2	0.2	1.3	0.5	1.0	1.5	1.3	0.9	0.3	1.2
Mood swings	0.4	0.7	3.4	-1.7	-0.7	-0.6	-0.4	-0.7	-1.9	-0.8	-1.0	-0.7	-0.6	-0.6	0.1	-0.5	-0.5	1.0	-0.5	-0.3	-1.0	-0.8	-0.7	-0.4	-0.7	0.2	-0.6
Medication: Gliclazide	0.4	0.5	3.0	-1.0	0.5	0.6	0.7	0.3	0.6	0.8	0.7	0.5	0.5	0.4	-1.7	0.3	0.1	0.5	-1.2	0.2	-0.9	-0.6	0.1	1.1	0.2	0.1	-0.2
Average weekly champagne plus white wine intake	0.4	0.5	2.5	0.0	-0.6	-0.3	-1.0	-0.8	-0.8	0.6	0.3	-0.5	-0.2	-0.7	0.7	-0.9	1.3	-1.0	1.1	0.1	0.2	-0.5	1.6	-0.5	0.2	0.0	-0.1
Miserableness	0.4	0.8	3.8	-2.0	-0.4	-0.3	-0.1	-0.3	-1.0	-0.9	-0.1	-0.3	-0.3	-0.2	-0.7	-0.0	-0.8	-1.9	-1.3	-0.8	-0.9	-1.1	-1.1	0.1	-0.1	-0.5	-1.4
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.2	0.4	0.8	0.8	1.1	0.9	0.8	0.8	0.6	0.8	0.9	0.8	-0.7	0.8	-0.5	0.2	-0.1	0.6	0.3	0.7	-0.3	0.9	0.4	-0.0	0.4
Eye problems/disorders: Glaucoma	0.4	0.5	3.1	-1.8	-0.5	-0.6	0.0	-0.7	-0.5	0.4	-0.4	-0.6	-0.7	-0.7	0.5	-0.5	-0.5	0.8	0.1	-0.5	-1.1	-0.6	0.2	-1.0	-1.3	-0.4	0.0
Pain experienced in last month	0.4	0.7	2.0	0.2	-1.1	-1.0	-1.4	-1.2	-0.2	-0.5	-1.1	-1.0	-1.0	-1.1	1.0	-1.4	-0.1	-0.2	0.9	-0.2	0.5	-0.7	0.3	-0.8	0.3	0.6	-0.7
Depression (Nagel 2018)	0.3	0.4	2.0	0.9	0.7	0.7	1.2	0.6	-0.2	0.4	0.0	0.6	0.6	0.6	-0.6	0.7	0.1	1.4	-0.2	0.5	-0.3	0.5	-0.2	0.5	-0.3	0.3	0.8
Crohns Disease (2012)	0.3	0.5	3.0	0.7	0.2	0.1	-0.5	0.2	0.7	-0.1	0.2	0.3	0.3	0.4	-0.5	0.3	-0.7	-0.8	-1.7	-0.7	-0.1	0.4	-1.4	0.4	0.1	-1.4	-0.7
HbA1C	0.3	0.3	1.6	-0.1	0.5	0.3	0.8	0.6	0.7	0.7	0.4	0.4	0.4	0.5	-0.4	0.3	-1.3	0.1	-0.8	-0.0	-0.3	0.7	-0.7	0.3	-0.4	-0.9	0.3
Lupus	0.3	0.4	1.4	1.2	-0.7	-1.1	0.2	-0.7	0.3	-0.5	0.0	-0.9	-1.1	-1.0	0.1	-0.7	-0.6	-0.2	-0.2	0.2	-0.7	-0.9	0.2	-0.2	-0.1	0.4	-0.5
Cardiovascular Disease	0.3	0.9	5.2	-1.7	-0.2	-0.4	0.6	-0.3	-0.8	0.0	-0.6	-0.4	-0.5	-0.2	-0.7	-0.0	-1.4	-0.3	-2.3	-1.1	-1.2	-0.5	-1.5	0.0	-0.8	-1.2	-1.1
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.7	-0.1	0.2	0.1	0.7	0.2	0.3	-0.3	-0.3	0.2	0.2	0.3	-0.5	0.2	-1.2	0.6	-1.6	-0.7	-0.3	0.6	-1.6	0.1	-0.5	-1.3	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.4	-0.2	-0.5	-0.5	0.0	-0.5	-1.2	-0.6	-1.0	-0.6	-0.6	-0.6	0.3	-0.5	-0.1	0.8	0.4	0.1	-1.0	-1.1	0.2	-0.5	-0.8	1.1	0.0
Sitting height	0.3	2.2	7.0	2.3	0.9	1.2	-1.1	0.9	1.8	0.3	1.6	1.2	1.1	1.1	-0.6	1.1	1.5	1.1	1.8	1.4	2.6	1.7	1.4	1.2	2.5	1.2	1.0
Alcohol usually taken with meals	0.3	0.5	2.8	0.5	0.2	0.1	0.0	0.3	0.6	0.0	1.0	0.1	-0.1	0.1	-0.5	-0.1	-1.3	-0.9	-1.7	-0.4	0.1	0.6	-1.5	0.5	0.4	-1.4	-0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.5	0.2	0.2	0.4	-0.0	0.3	0.7	0.4	0.5	0.3	0.5	0.2	-0.1	0.5	0.4	-0.2	0.8	0.9	1.1	0.2	0.6	0.6	1.2	0.8	0.3
Allergy	0.3	0.7	2.1	0.4	0.6	0.7	1.0	0.4	0.8	1.0	1.3	0.6	0.8	0.5	-0.5	0.7	1.4	-0.4	0.8	0.8	0.6	-0.0	1.5	0.8	1.1	0.7	0.4
Diabetes (self-reported)	0.3	0.5	3.7	-0.2	0.0	0.2	0.3	0.1	0.1	-0.2	-0.0	0.1	0.2	0.1	-0.8	-0.0	-1.1	0.4	-1.9	-0.7	-0.8	0.1	-1.5	0.4	-0.3	-1.4	-1.0
Medication: Ramipril	0.3	0.3	1.5	-0.1	0.4	0.3	0.9	0.3	0.7	0.7	0.6	0.4	0.3	0.4	-1.1	0.3	0.5	0.2	-1.2	-0.5	-0.6	-0.0	-0.0	0.5	-0.0	-1.1	-0.4
Neuroticism score	0.3	0.6	3.7	-1.8	-0.8	-0.6	-0.1	-0.8	-1.9	-0.9	-0.8	-0.7	-0.6	-0.8	0.1	-0.6	-0.2	0.5	-0.4	-0.6	-0.8	-0.8	-0.5	-0.5	-0.5	0.1	-0.7
Asthma	0.3	0.6	2.8	-0.4	-0.7	-0.9	-1.7	-0.5	-0.9	-1.1	-1.0	-0.8	-1.0	-0.7	0.7	-0.6	-0.6	-0.7	-0.1	-0.7	-0.8	-0.7	-0.2	-0.8	-0.8	-0.3	-0.7
Wheeze or whistling in the chest in last year	0.3	0.5	2.0	-1.0	-0.6	-0.8	-0.1	-0.6	-0.7	-0.4	-0.6	-0.7	-0.8	-0.6	0.2	-0.7	0.4	-1.2	0.3	-0.4	-0.9	-1.4	0.7	-0.6	-0.5	0.3	-0.6
Migraine (self-reported)	0.3	0.4	2.6	0.7	0.7	0.9	-0.2	0.8	1.6	0.4	0.5	0.8	0.9	0.9	-0.3	0.7	0.5	0.1	-0.2	0.1	0.3	0.6	-0.1	0.7	0.4	-0.4	0.3
Suffer from ‘nerves’	0.3	0.4	2.3	-0.6	0.1	-0.0	0.8	0.2	-1.0	0.5	-0.5	0.0	0.0	0.1	0.2	0.0	0.4	1.5	1.1	0.5	0.9	0.8	0.8	-0.2	0.2	0.7	0.9
Family relationship satisfaction	0.3	0.4	1.0	0.3	0.7	0.6	0.7	0.6	0.8	0.8	-0.1	0.7	0.6	0.7	-0.8	0.6	0.9	0.6	-0.1	0.5	0.5	0.5	0.5	1.0	1.0	0.4	0.3
Loneliness, isolation	0.3	0.5	1.2	0.3	0.4	0.8	1.1	0.2	-0.4	0.8	0.5	0.6	0.9	0.4	-1.0	0.6	1.0	1.1	-0.1	0.7	-0.1	-0.1	0.9	0.9	0.4	0.8	0.6
Friendships satisfaction	0.3	0.4	1.0	0.6	0.6	0.8	0.8	0.7	0.7	0.8	-0.1	0.7	0.8	0.7	-0.9	0.6	-0.5	1.0	-0.5	0.6	-0.0	0.5	-0.5	0.8	0.2	0.0	0.4
Qualifications: nursing, teaching	0.3	0.5	2.1	1.5	0.4	0.5	0.5	0.4	0.8	0.8	0.9	0.4	0.6	0.5	-1.2	0.3	-0.7	-0.3	-1.3	0.3	-0.5	0.2	-0.5	1.0	0.4	-0.8	-0.2
Arm fat mass (left)	0.3	1.2	2.5	-1.2	-1.5	-1.4	-0.9	-1.5	-1.5	-0.4	-1.6	-1.5	-1.4	-1.5	0.7	-1.3	-0.1	-0.2	0.1	-0.7	-1.1	-1.3	0.3	-1.2	-1.0	0.1	-0.8
Number of self-reported non-cancer illnesses	0.3	0.6	3.3	-0.8	-0.1	-0.1	0.2	0.1	-0.3	0.2	-0.6	-0.0	-0.0	-0.0	-0.3	0.1	-1.3	0.4	-1.8	-0.8	-0.9	0.4	-1.4	-0.0	-0.9	-1.7	-0.6
Hearing aid user	0.3	0.4	1.1	0.8	0.7	0.8	0.8	0.7	0.5	0.3	0.2	0.8	0.9	0.7	-0.1	0.6	0.5	0.6	0.0	0.1	0.8	1.0	-0.0	0.5	0.4	-0.2	0.5
Medication: Atorvastatin	0.3	0.3	3.1	1.8	0.4	0.3	0.4	0.4	0.4	0.3	0.3	0.3	0.3	0.4	-0.8	0.6	0.9	0.3	0.3	0.4	0.2	0.0	0.7	0.4	0.5	0.5	0.4
Risk taking	0.3	0.5	2.5	-0.3	0.8	0.7	0.1	0.5	1.6	0.3	0.8	0.8	0.7	0.8	-1.0	0.9	0.2	0.8	-1.1	-0.2	-0.7	0.4	-0.3	0.6	-0.4	-0.8	0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	2.6	0.7	-0.2	-0.2	-0.5	-0.2	-0.5	-0.2	-0.1	-0.1	-0.1	-0.2	0.1	-0.3	-0.4	-0.8	-0.9	-0.7	-0.0	0.2	-0.7	0.0	0.3	-1.6	-1.0
Diastolic blood pressure, automated reading	0.3	1.0	5.5	-2.3	-1.0	-0.9	-1.2	-1.1	-1.5	-1.3	-1.3	-1.0	-1.0	-0.9	1.2	-0.8	-0.3	-0.4	0.1	-0.8	-0.2	-0.7	-0.5	-0.9	-0.4	0.6	-0.7
Intelligence (Savage-Jansen 2018)	0.2	0.7	3.3	-0.2	-0.6	-0.9	-0.2	-0.7	0.7	-0.3	-0.3	-0.7	-0.8	-0.6	-0.6	-0.7	-0.9	-0.5	-1.5	-0.8	-1.8	-1.4	-0.8	-0.2	-0.8	-0.7	-1.3
Crohns Disease (2017)	0.2	0.5	1.2	0.4	0.7	0.8	0.0	0.8	1.0	0.6	0.8	0.8	0.9	0.8	-0.8	0.8	0.2	0.0	-0.5	0.2	0.8	1.1	-0.3	0.8	0.7	-0.8	0.2
Prostate Cancer	0.2	0.3	0.9	-0.1	0.5	0.4	0.2	0.7	0.0	0.1	0.8	0.5	0.5	0.6	-0.3	0.7	-0.8	-0.3	-0.7	-0.1	0.2	0.8	-0.9	0.4	0.1	-0.9	0.1
LDL Cholesterol	0.2	0.3	0.9	0.9	0.6	0.6	0.9	0.6	-0.0	0.2	0.8	0.5	0.6	0.5	-0.8	0.8	0.3	0.0	-0.4	0.1	-0.2	0.2	-0.1	0.6	0.0	-0.3	0.0
Primary Biliary Cirrhosis	0.2	0.2	0.6	-0.8	-0.5	-0.5	0.3	-0.6	-0.6	-0.2	-0.6	-0.7	-0.6	-0.5	0.4	-0.6	0.0	0.3	0.4	-0.2	0.6	0.2	-0.1	-0.6	-0.1	0.5	0.0
Triglycerides	0.2	0.3	1.2	-0.9	0.1	0.2	-0.4	-0.0	-0.7	-0.4	-0.1	0.1	0.0	0.1	-0.5	0.3	-0.2	0.7	-1.1	-0.4	-0.8	0.2	-0.8	0.1	-0.5	-1.0	-0.3
Blood Eosinophil Count	0.2	1.9	9.8	3.1	1.5	1.1	1.1	1.7	1.5	1.6	1.2	1.3	1.0	1.4	-1.5	1.4	0.3	0.1	0.6	1.4	1.3	1.4	1.0	1.4	1.4	0.2	1.3
Blood Platelet Count	0.2	1.9	6.7	0.7	1.5	1.7	1.5	1.8	1.4	1.1	1.4	1.5	1.7	1.5	-2.6	1.3	-0.7	1.4	-1.7	0.8	-0.3	1.0	-0.9	1.8	0.5	-0.8	0.6
Lung FEV1/FVC ratio	0.2	1.0	6.8	1.0	0.5	0.5	0.0	0.3	1.0	0.2	0.7	0.5	0.5	0.5	-1.1	0.4	-0.9	-0.2	-2.6	-1.0	-1.1	0.3	-1.6	0.6	-0.5	-2.4	-0.8
Number of treatments/medications taken	0.2	0.4	1.3	0.7	0.7	0.7	1.1	0.8	0.5	0.8	0.2	0.7	0.7	0.7	-0.9	0.8	0.5	1.0	-0.5	0.4	-0.4	0.2	0.2	0.8	0.0	0.3	0.6
Angina	0.2	0.2	1.0	0.3	-0.1	-0.2	-0.6	-0.3	-0.4	-0.4	0.2	-0.1	-0.1	-0.1	-0.4	-0.1	-0.3	-0.0	-1.0	-0.5	-1.0	-0.5	-0.6	0.1	-0.5	-0.5	-0.6
Townsend deprivation index at recruitment	0.2	0.3	1.8	-0.9	-0.5	-0.4	-0.6	-0.5	-0.1	0.2	0.0	-0.4	-0.3	-0.5	-0.3	-0.6	0.2	-1.3	-0.5	-0.2	-0.7	-1.2	0.3	0.1	0.2	0.1	-0.9
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.4	-0.1	-0.6	-0.5	-0.9	-0.6	-0.8	-1.1	-1.2	-0.6	-0.8	-0.6	0.9	-0.6	-0.9	0.7	-0.2	-0.7	-0.4	-0.0	-1.1	-1.0	-1.1	-0.1	-0.1
High blood pressure (mother)	0.2	0.2	1.2	1.1	0.2	0.2	0.5	0.3	0.5	-0.1	0.5	0.2	0.1	0.1	-0.5	0.1	0.9	-0.1	0.4	0.4	0.6	0.1	0.5	0.4	0.8	0.7	0.2
Past tobacco smoking	0.2	0.4	1.4	0.8	0.5	0.4	-0.4	0.4	1.2	0.6	0.2	0.5	0.4	0.5	-0.7	0.7	0.6	0.6	0.7	0.7	0.9	0.5	0.9	0.6	1.0	0.7	0.6
Qualifications: None of the above	0.2	0.5	1.1	0.5	0.8	0.9	0.9	1.0	-0.5	0.1	0.7	0.9	1.1	0.8	-0.7	1.1	0.8	-0.0	0.1	0.3	0.9	0.6	-0.2	0.8	0.8	0.2	0.2
Mouth/teeth dental problems	0.2	0.4	2.3	-1.5	-0.4	-0.4	-1.2	-0.3	-0.5	-1.0	0.8	-0.3	-0.2	-0.3	-0.3	-0.4	-0.4	-0.0	-0.6	-0.2	-0.1	-0.4	-0.8	0.2	0.3	0.6	-0.7
Happiness	0.2	0.3	0.6	0.1	0.4	0.5	0.6	0.3	0.4	0.5	0.3	0.5	0.6	0.5	-0.4	0.4	0.6	0.8	0.2	0.4	0.7	0.8	0.5	0.5	0.7	-0.1	0.4
Noisy workplace	0.2	0.2	0.9	-0.9	0.1	-0.2	0.0	0.0	-0.9	-0.3	-0.9	-0.0	-0.2	0.0	0.3	0.2	-0.4	0.8	-0.2	-0.5	-0.6	-0.2	-0.6	-0.4	-0.9	-0.0	0.1
Medication: Cholesterol lowering	0.2	0.4	2.4	-0.2	0.1	0.0	0.4	0.0	0.3	0.2	0.5	0.1	0.1	0.0	-0.9	0.1	-0.2	-0.9	-1.6	-0.6	-0.7	-0.3	-0.6	0.5	0.1	-1.4	-1.1
Illnesses of mother	0.2	0.3	1.9	-1.4	0.2	0.2	-0.1	0.1	-0.2	0.4	0.1	0.3	0.3	0.2	0.1	0.3	-0.8	0.1	-0.8	-0.5	-0.1	0.6	-0.7	0.0	-0.4	-1.4	-0.3
Arm fat mass (right)	0.2	0.9	2.0	-1.0	-1.3	-1.2	-0.7	-1.3	-1.2	-0.3	-1.4	-1.3	-1.2	-1.3	0.6	-1.1	0.1	-0.3	0.1	-0.6	-1.1	-1.3	0.5	-1.1	-0.9	0.1	-0.7
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.9	-0.2	-0.2	-0.3	0.0	-0.3	-0.8	-0.3	-0.3	-0.2	-0.1	-0.3	0.1	-0.2	-0.7	0.0	-0.9	-0.4	-1.0	-0.5	-0.7	-0.1	-0.7	-0.4	-0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	2.1	0.3	-0.1	-0.1	0.3	-0.1	0.3	1.0	0.1	-0.1	-0.1	-0.2	-0.6	-0.3	-0.8	-0.5	-1.1	-0.3	-0.5	0.1	-0.3	0.1	-0.3	-1.4	-0.4
Age at first live birth	0.2	0.3	2.1	-0.5	-0.0	-0.2	-0.1	-0.2	0.4	0.1	0.2	-0.1	-0.2	-0.0	-0.3	-0.2	-0.3	-1.4	-0.9	-0.9	-0.8	-0.7	-0.5	-0.1	-0.5	-0.8	-0.8
Shortness of breath walking on level ground	0.2	0.3	0.8	0.9	-0.5	-0.3	-0.4	-0.4	-0.3	-0.7	-0.4	-0.4	-0.3	-0.6	0.6	-0.6	-0.8	0.7	0.2	-0.1	0.0	0.2	-0.8	-0.7	-0.7	0.2	0.1
Neck or shoulder pain in last month	0.2	0.3	1.7	-0.6	0.1	-0.1	0.2	-0.0	-0.9	0.2	-0.2	-0.0	0.0	-0.0	-0.2	0.1	-0.9	-0.1	-0.9	-0.6	-0.9	0.0	-0.7	-0.3	-1.2	-1.3	-0.1
Mean time to correctly identify matches	0.2	0.4	2.2	-0.4	0.6	0.4	1.0	0.3	-0.0	1.5	0.2	0.5	0.6	0.4	-0.2	0.4	0.2	0.6	-0.1	0.2	-0.1	0.9	0.6	0.0	-0.4	-1.0	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	1.3	-1.1	0.3	0.2	0.7	0.1	0.2	0.3	-0.5	0.2	0.0	0.3	-0.2	0.1	1.0	0.1	0.4	0.3	-0.1	-0.5	0.9	0.2	0.1	1.0	0.4
Comparative height size at age 10	0.2	0.9	2.5	0.2	-1.2	-1.0	-1.6	-1.1	-1.3	-1.5	-0.8	-1.1	-1.1	-1.0	1.4	-0.9	-1.0	1.2	0.2	-0.4	-0.0	-0.1	-1.0	-1.2	-0.6	0.4	-0.3
Age at last live birth	0.2	0.3	1.4	0.2	0.7	0.7	1.2	0.5	0.7	0.9	0.7	0.6	0.7	0.6	-0.5	0.5	0.5	-0.7	-0.1	0.2	-0.3	-0.2	0.4	0.5	-0.0	0.1	0.3
Smoking status: Previous	0.2	0.3	1.7	0.0	0.6	0.6	1.3	0.7	0.1	0.4	0.7	0.5	0.5	0.5	0.0	0.3	0.5	-0.2	0.4	0.5	0.6	0.7	0.5	0.2	0.2	-0.1	0.7
Diabetes diagnosed by doctor	0.2	0.4	2.8	0.3	0.2	0.1	0.7	0.3	0.5	0.1	0.0	0.2	0.2	0.3	-0.9	0.2	-0.9	0.5	-1.7	-0.4	-0.7	0.1	-1.1	0.6	-0.1	-1.0	-0.7
Breast cancer (self-reported)	0.2	0.3	2.2	-0.4	0.4	0.2	1.5	0.2	-0.3	0.5	0.5	0.3	0.2	0.4	-0.4	0.3	-0.0	1.1	0.1	0.5	-0.1	0.5	0.4	0.3	-0.0	0.5	0.7
Asthma (self-reported)	0.2	0.4	1.8	-0.3	-0.6	-0.8	-1.4	-0.4	-0.8	-0.8	-0.9	-0.7	-0.9	-0.5	0.5	-0.5	-0.6	-0.6	-0.1	-0.5	-0.7	-0.6	-0.1	-0.7	-0.7	-0.3	-0.4
Medication: Aspirin	0.2	0.3	1.5	-0.7	-0.3	-0.1	-0.2	-0.3	-0.1	0.2	-0.3	-0.2	-0.2	-0.2	-0.6	-0.3	0.0	-0.4	-0.9	0.2	-1.0	-1.2	0.1	0.6	0.2	0.9	-0.5
Commuting to job workplace: Public transport	0.2	0.2	2.3	-0.1	-0.2	-0.4	-0.5	-0.3	0.0	0.3	0.1	-0.3	-0.4	-0.2	0.5	-0.4	0.7	-1.5	0.2	-0.2	-0.4	-0.8	0.7	-0.2	0.1	-0.1	-0.4
Ever depressed for a whole week	0.2	0.3	1.0	-0.7	0.3	0.5	-0.8	0.3	0.3	-0.2	0.1	0.4	0.5	0.5	-0.1	0.7	0.1	1.0	0.6	0.7	0.5	0.2	0.1	0.4	0.6	0.6	0.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.4	0.1	0.1	0.1	0.3	-0.2	0.1	0.3	0.6	0.0	0.1	0.0	0.5	-0.2	0.5	0.2	0.2	-0.1	-0.3	0.2	0.7	-0.3	-0.6	-0.2	0.7
Worry (Nagel 2018)	0.1	0.2	0.9	-0.6	-0.2	-0.1	0.9	-0.2	-0.8	-0.1	-0.1	-0.1	0.0	-0.3	0.1	-0.2	1.0	0.4	0.5	0.1	0.3	0.2	0.5	-0.2	0.2	0.5	0.4
Breast Cancer	0.1	0.2	0.9	0.9	-0.1	0.3	-0.6	-0.0	0.7	0.5	-0.9	0.1	0.3	-0.1	0.3	-0.3	0.1	0.7	0.4	0.4	0.3	0.2	0.2	-0.0	-0.1	0.3	0.5
Neuroticism (2016)	0.1	0.2	1.7	-1.3	0.0	0.2	-0.5	-0.2	-1.0	-0.3	-0.3	-0.1	0.0	0.1	0.4	0.3	0.3	0.1	0.2	-0.5	-0.1	0.0	0.1	-0.3	-0.3	-0.5	0.0
Blood Red Count	0.1	1.1	4.3	-0.9	-1.3	-1.4	-1.0	-1.1	-0.3	-2.0	-0.9	-1.4	-1.4	-1.2	2.1	-1.2	-0.0	1.0	0.8	-0.6	0.5	0.0	-0.3	-1.4	-0.2	0.7	-0.3
Blood White Count	0.1	0.5	3.6	1.9	-0.8	-0.8	-0.7	-0.5	0.4	-0.4	-0.9	-0.9	-0.8	-0.9	0.2	-0.9	-0.9	0.4	-0.3	-0.1	0.2	-0.2	-0.6	-0.3	0.3	0.0	-0.7
Waist Hip Ratio (WHR)	0.1	0.4	2.0	0.5	0.5	0.5	1.4	0.3	-0.1	0.6	1.3	0.4	0.5	0.3	-0.8	0.3	-0.1	0.4	-1.1	-0.0	-0.8	0.1	0.0	0.5	-0.3	-0.8	0.2
Systolic Blood Pressure	0.1	0.5	2.4	-1.5	-0.8	-0.6	-0.6	-0.9	-0.8	-0.3	0.2	-0.8	-0.7	-0.9	0.6	-0.9	-0.4	-0.3	-0.5	-0.9	-0.6	-0.5	-0.3	-0.8	-0.7	-0.4	-0.7
Allergy or Eczema	0.1	0.4	3.8	2.0	0.3	0.5	0.5	0.4	0.6	0.3	-0.2	0.4	0.2	0.3	0.1	0.2	0.4	1.2	0.4	0.4	0.2	0.7	0.2	0.0	-0.2	0.3	0.8
Neuroticism	0.1	0.3	2.6	-1.3	-0.1	0.2	0.6	-0.1	-1.6	-0.5	-0.4	0.0	0.3	-0.2	-0.4	-0.0	0.1	0.7	-0.5	0.1	-0.2	-0.3	-0.5	0.2	-0.0	0.6	-0.0
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.1	-0.2	0.0	-0.0	0.2	-0.1	-0.5	0.1	-0.9	-0.0	-0.1	0.1	-0.7	0.1	-0.4	1.0	-0.8	0.0	-0.5	0.1	-0.5	0.2	-0.3	0.0	0.1
Medication: Metformin	0.1	0.1	0.9	-0.0	-0.0	-0.0	0.8	-0.0	-0.0	0.1	-0.2	-0.0	0.0	0.0	-0.8	-0.2	-0.2	0.4	-0.9	-0.1	-0.5	-0.2	-0.4	0.4	0.0	-0.3	-0.5
Fed-up feelings	0.1	0.3	1.9	-1.3	-0.3	-0.1	-0.2	-0.3	-1.4	-0.4	-0.4	-0.2	-0.1	-0.3	-0.3	-0.1	0.8	-0.0	0.1	-0.1	-0.3	-0.8	0.4	0.0	0.2	0.3	-0.6
Supplements: Glucosamine	0.1	0.1	0.6	0.5	0.1	0.2	0.6	0.2	0.3	0.4	0.2	0.1	0.2	0.1	0.0	0.0	-0.5	0.8	-0.3	0.1	-0.3	0.4	-0.3	0.1	-0.4	-0.2	0.3
Trunk fat mass	0.1	0.5	2.0	0.7	0.3	0.6	0.5	0.3	0.2	1.1	0.1	0.4	0.5	0.4	-1.0	0.4	1.4	0.7	0.4	0.9	0.2	0.2	1.4	0.7	0.7	0.6	0.6
Hearing difficulty/problems with background noise	0.1	0.2	1.9	-1.4	0.4	0.3	0.6	0.2	-0.3	-0.5	-0.5	0.4	0.4	0.5	0.2	0.4	0.5	-0.9	0.1	-0.4	-0.0	-0.2	0.0	-0.0	-0.1	0.1	0.0
Pain all over the body in last month	0.1	0.1	0.8	-0.5	0.4	0.3	0.2	0.3	-0.0	0.3	-0.9	0.3	0.3	0.5	-0.2	0.2	0.2	-0.3	-0.3	-0.2	-0.4	-0.1	0.0	0.2	-0.3	-0.0	0.2
Hip circumference	0.1	0.6	1.5	-0.4	-1.0	-0.9	-1.1	-1.1	-0.8	-0.5	-1.2	-1.0	-0.9	-0.9	0.6	-0.8	0.4	-0.3	0.3	-0.5	-0.8	-1.2	0.5	-0.9	-0.7	0.4	-0.6
Father’s age at death	0.1	0.1	1.0	-0.2	0.3	-0.1	0.2	0.3	0.1	0.5	-0.0	0.1	0.0	0.2	0.3	0.1	-0.8	-0.1	-0.1	-0.2	0.1	0.5	-0.3	-0.1	-0.2	-1.0	0.0
Worrier / anxious feelings	0.1	0.2	1.7	-1.1	-0.0	0.0	0.5	-0.1	-0.4	-0.1	0.0	-0.1	0.0	-0.1	-0.0	-0.1	0.0	0.5	-0.8	-0.8	-0.4	0.4	-0.4	-0.3	-0.7	-1.3	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.4	-0.3	0.3	0.4	0.3	0.4	-1.2	0.2	-0.0	0.3	0.3	0.3	-0.9	0.5	0.1	0.5	0.2	0.6	-0.1	-0.3	0.2	0.5	0.3	1.0	0.3
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.6	-0.9	-0.3	-0.4	0.2	-0.3	0.2	0.4	0.7	-0.4	-0.4	-0.4	-0.8	-0.5	-0.2	-1.3	-0.7	0.0	-0.3	-0.6	0.1	0.4	0.7	-0.5	-0.8
Pulse wave Arterial Stiffness index	0.1	0.1	0.8	0.8	0.4	0.3	0.9	0.4	-0.0	-0.1	-0.4	0.3	0.2	0.2	0.1	0.3	-0.2	-0.2	0.0	-0.1	-0.3	0.0	0.1	-0.0	-0.4	-0.4	0.2
Standing height	0.1	1.2	4.1	0.9	0.3	0.6	-1.2	0.4	0.9	-0.6	0.8	0.5	0.5	0.5	-0.3	0.5	0.9	1.6	1.5	1.3	2.0	1.0	0.8	0.9	2.0	2.0	0.7
Leg fat percentage (right)	0.1	0.3	1.2	-0.3	-0.6	-0.4	0.3	-0.6	-0.7	0.1	-1.1	-0.6	-0.3	-0.6	-0.1	-0.5	1.0	-0.5	0.0	-0.2	-0.8	-0.9	0.8	-0.4	-0.4	0.1	-0.4
Pulse wave peak to peak time	0.1	0.2	1.2	-0.7	-0.5	-0.4	-1.1	-0.5	0.0	-0.0	0.3	-0.4	-0.4	-0.4	0.0	-0.4	0.1	0.2	-0.0	-0.0	0.3	-0.0	-0.2	-0.1	0.4	0.3	-0.3
Qualifications: College or University degree	0.1	0.3	1.1	-0.1	-0.4	-0.5	-1.0	-0.5	0.4	-0.3	-0.1	-0.4	-0.5	-0.4	-0.2	-0.4	-1.0	-0.4	-0.9	-0.1	-0.8	-0.4	-0.6	0.1	-0.2	-0.4	-0.5
Angina (self-reported)	0.1	0.2	0.9	0.1	0.0	-0.1	-0.6	-0.2	-0.4	-0.4	0.3	-0.0	-0.0	0.0	-0.5	0.0	-0.1	-0.1	-0.9	-0.4	-0.9	-0.5	-0.5	0.2	-0.3	-0.3	-0.6
Whole body fat mass	0.1	0.5	1.2	-0.5	-1.1	-0.8	-0.7	-1.1	-1.1	-0.2	-1.1	-1.0	-0.8	-1.0	0.1	-0.9	0.5	0.1	0.1	-0.3	-0.8	-1.0	0.6	-0.6	-0.4	0.3	-0.6
Overall health rating	0.1	0.2	0.7	-0.3	0.5	0.6	0.7	0.4	-0.3	0.8	0.1	0.5	0.5	0.5	-0.8	0.6	0.6	0.5	-0.3	0.2	-0.3	0.3	0.4	0.4	-0.1	0.1	0.5
Knee pain experienced in last month	0.1	0.2	0.6	-0.8	0.4	0.5	0.3	0.5	-0.2	-0.2	0.8	0.4	0.4	0.5	-0.4	0.8	-0.2	0.2	-0.5	0.1	-0.0	0.4	-0.5	0.4	0.0	-0.1	0.3
Ever had bowel cancer screening	0.1	0.1	0.4	-0.2	0.4	0.3	-0.5	0.3	0.1	-0.1	0.0	0.4	0.3	0.5	-0.2	0.5	0.6	-0.2	-0.2	-0.4	-0.0	0.1	0.0	0.2	0.2	-0.5	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.5	0.4	0.4	0.4	0.4	0.4	0.7	0.0	-0.5	0.4	0.3	0.4	0.3	0.4	-0.1	-0.1	-0.2	-0.3	0.0	0.4	-0.3	-0.1	-0.4	-0.6	0.3
Guilty feelings	0.1	0.1	1.0	-1.0	0.0	-0.0	0.3	-0.1	-0.6	-0.1	-0.3	-0.0	0.0	-0.0	0.2	0.1	0.2	1.0	0.4	0.1	0.0	0.0	0.2	-0.2	-0.2	0.5	0.3
Medication: Blood pressure	0.1	0.2	1.1	-0.6	-0.4	-0.1	0.4	-0.5	-0.2	-0.1	-0.6	-0.4	-0.3	-0.4	0.3	-0.3	0.1	-0.1	-0.3	-0.3	-1.0	-0.9	0.3	-0.4	-1.0	0.6	0.1
Pain type(s) experienced in last month: Hip pain	0.1	0.2	1.4	0.1	-0.4	-0.3	0.2	-0.3	-0.7	-0.0	-0.4	-0.3	-0.1	-0.3	0.6	-0.1	-0.4	1.2	0.2	0.2	-0.5	-0.3	0.1	-0.3	-0.6	0.2	0.1
High cholesterol (Self-reported)	0.1	0.1	0.8	-0.4	0.0	-0.0	0.9	0.0	0.5	0.3	0.3	0.0	0.1	-0.0	-0.5	0.2	0.1	-0.2	-0.4	0.2	-0.0	-0.2	0.2	0.5	0.5	0.1	-0.4
Medication: Bendroflumethiazide	0.1	0.2	1.1	-1.0	-0.2	-0.1	0.5	-0.2	-0.5	0.1	-0.1	-0.3	-0.3	-0.3	-0.6	-0.3	-0.0	-0.4	-0.9	-0.3	-0.6	-0.5	0.0	0.2	-0.1	-0.2	-0.5
Ever smoked	0.1	0.2	1.3	-0.5	-0.1	-0.0	0.8	0.1	-0.6	-0.2	0.3	-0.1	-0.0	-0.2	0.3	-0.3	-0.3	-1.1	-0.4	-0.3	-0.4	-0.3	-0.7	-0.1	-0.4	-0.3	-0.4
Leg fat percentage (left)	0.1	0.4	1.4	-0.6	-0.7	-0.4	0.3	-0.7	-0.9	0.1	-0.9	-0.6	-0.4	-0.6	0.1	-0.6	1.2	-0.6	0.1	-0.3	-0.8	-1.0	0.9	-0.5	-0.4	0.1	-0.4
Average weekly beer plus cider intake	0.1	0.2	0.6	-0.3	-0.4	-0.4	-0.2	-0.5	0.2	0.2	-0.7	-0.3	-0.1	-0.4	0.2	-0.3	-0.2	-0.2	-0.3	-0.6	-0.7	-0.5	-0.1	-0.5	-0.8	-0.6	-0.3
Fractured/broken bones in last 5 years	0.1	0.1	1.8	-1.4	-0.1	-0.1	-0.3	-0.1	0.3	-0.1	-0.2	-0.2	-0.1	-0.1	-0.2	-0.1	0.4	-0.6	-0.1	-0.1	-0.2	-0.5	0.2	0.0	0.2	-0.1	-0.4
Supplements: Calcium	0.1	0.1	0.7	0.2	0.1	-0.2	0.5	0.1	0.6	-0.2	0.1	0.0	-0.1	0.2	0.1	0.2	0.9	-0.3	0.4	0.0	-0.1	-0.5	0.5	0.0	0.2	0.6	0.0
Height	0.0	0.8	3.9	1.1	-0.6	-0.5	-1.4	-0.8	0.3	-1.0	-0.0	-0.2	0.2	-0.5	0.9	-0.5	0.6	1.4	1.9	0.8	1.0	0.2	0.9	-0.4	0.4	2.0	0.7
Hair Pigment	0.0	0.3	0.9	-0.1	0.6	0.7	0.4	0.6	0.9	0.2	0.2	0.6	0.6	0.7	-0.1	0.7	0.7	-0.5	0.4	0.3	0.4	0.0	0.5	0.3	0.5	0.7	0.3
Tanning	0.0	0.5	2.5	-1.6	-0.8	-0.8	-0.1	-0.7	-0.9	-0.1	-0.5	-0.8	-0.7	-0.8	1.3	-0.8	-0.5	-0.1	0.2	-0.5	-0.4	-0.3	-0.1	-1.0	-0.8	-0.9	-0.4
Medication for cholesterol	0.0	0.1	0.4	0.1	-0.0	-0.1	-0.3	-0.1	0.1	-0.2	0.0	0.0	-0.1	0.0	-0.0	-0.1	-0.4	0.4	-0.3	-0.1	-0.2	0.1	-0.6	0.0	-0.0	-0.3	-0.2

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