Best TWAS P=6.44e-14 · Best GWAS P=1.36e-13 conditioned to 0.0235
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | C5orf34 | 0.10 | 0.01 | enet | 20 | 0.01 | 0.02960 | 0.79 | 6.0 | 1.6e-09 | -0.62 | 0.02 | 0.76 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | NNT-AS1 | 0.12 | -0.01 | enet | 34 | 0.03 | 0.02100 | -7.30 | 7.5 | 6.4e-14 | -0.50 | 0.02 | 0.55 | TRUE |
| 3 | GTEx | Pancreas | AC025171.1 | 0.14 | 0.05 | lasso | 2 | 0.07 | 0.00092 | -5.50 | -6.3 | 2.4e-10 | 0.76 | 0.05 | 0.82 | TRUE |
| 4 | GTEx | Stomach | ZNF131 | 0.10 | 0.05 | enet | 13 | 0.04 | 0.00332 | -7.11 | -5.2 | 1.6e-07 | 0.83 | 0.02 | 0.96 | FALSE |
| 5 | GTEx | Whole Blood | CTD-2201E18.3 | 0.08 | 0.00 | lasso | 5 | 0.02 | 0.01020 | -7.26 | -6.0 | 2.5e-09 | 0.63 | 0.04 | 0.32 | FALSE |