TWAS hub - NNT-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1100	0.0510	1.4e-03	0.056	NA	0.004	NA	0.017	2.3e-05	NA	1.3e-01	NA	1.4e-02
2	GTEx	Adrenal Gland	0.1437	0.0675	6.7e-03	0.009	NA	-0.004	NA	-0.002	1.5e-01	NA	5.0e-01	NA	4.0e-01
3	GTEx	Artery Tibial	0.0833	0.0424	6.9e-03	0.004	NA	0.020	NA	0.013	1.5e-01	NA	9.8e-03	NA	3.0e-02
4	GTEx	Cells EBV-transformed lymphocytes	0.1640	0.0570	2.8e-05	0.143	NA	0.092	NA	0.074	2.2e-05	NA	6.6e-04	NA	2.0e-03
5	GTEx	Cells Transformed fibroblasts	0.0800	0.0290	3.8e-06	0.036	NA	0.038	NA	0.053	9.6e-04	NA	7.7e-04	NA	7.8e-05
6	GTEx	Colon Transverse	0.1070	0.0490	9.6e-03	0.072	NA	0.024	NA	0.071	2.7e-04	NA	2.5e-02	NA	2.9e-04
7	GTEx	Esophagus Gastroesophageal Junction	0.1250	0.0530	6.3e-03	-0.008	NA	0.034	NA	-0.008	9.5e-01	NA	2.1e-02	NA	9.8e-01
8	GTEx	Esophagus Mucosa	0.1130	0.0430	8.4e-04	-0.004	NA	0.010	NA	0.009	7.4e-01	NA	7.1e-02	NA	7.7e-02
9	GTEx	Esophagus Muscularis	0.1830	0.0580	1.1e-05	0.017	NA	0.059	NA	0.048	3.2e-02	NA	1.9e-04	NA	7.0e-04
10	GTEx	Lung	0.0717	0.0329	7.5e-03	0.025	NA	0.000	NA	0.015	4.8e-03	NA	3.0e-01	NA	2.3e-02
11	GTEx	Muscle Skeletal	0.0489	0.0288	9.6e-03	0.041	NA	0.025	NA	0.029	6.6e-05	NA	1.4e-03	NA	6.6e-04
12	GTEx	Nerve Tibial	0.1123	0.0409	3.2e-04	0.022	NA	0.068	NA	0.064	9.8e-03	NA	1.4e-05	NA	2.6e-05
13	GTEx	Pituitary	0.2930	0.0970	2.0e-04	0.203	NA	0.169	NA	0.163	8.2e-06	NA	5.0e-05	NA	6.9e-05
14	GTEx	Spleen	0.4020	0.0940	4.2e-06	0.008	NA	0.232	NA	0.149	1.9e-01	NA	1.2e-06	NA	1.2e-04
15	GTEx	Thyroid	0.1080	0.0360	9.2e-06	0.109	NA	0.067	NA	0.096	1.1e-08	NA	8.0e-06	NA	8.9e-08
16	GTEx	Uterus	0.2770	0.1210	4.9e-03	-0.010	NA	-0.010	NA	-0.008	5.8e-01	NA	5.8e-01	NA	5.0e-01
17	GTEx	Whole Blood	0.0970	0.0390	6.2e-04	0.000	NA	0.014	NA	0.008	2.9e-01	NA	1.6e-02	NA	5.0e-02
18	ROSMAP	Brain Pre-frontal Cortex	0.1525	0.0427	0.0e+00	0.172	0.167	0.160	0.165	0.163	1.4e-21	5.6e-21	4.2e-20	1.3e-20	1.8e-20

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Diabetes (father)	5.6	6.9	15.5	3.7	3.2	2.1	3.9	3.8	3.6	-0.2	2.1	2.2	0.9	-2.2	2.0	3.2	0.9	3.3	1.0	0.9	3.4
Breast cancer (self-reported)	5.5	6.5	13.0	-3.4	-3.5	-2.5	-3.2	-2.7	-3.6	-3.3	-1.2	-2.6	-1.0	1.0	-2.7	-2.1	-1.1	-3.4	-0.3	-0.5	-3.5
Alzheimer’s Disease (in father)	5.0	5.4	16.0	-2.8	-2.9	-2.0	-3.2	-2.6	-2.5	-0.3	-1.9	-0.8	-0.4	1.2	-2.6	-0.7	-2.4	-2.7	-0.4	-4.0	-3.5
Frequency of depressed mood in last 2 weeks	4.4	6.1	14.6	2.7	2.5	2.9	2.1	0.9	2.8	2.8	2.2	2.6	2.1	0.6	3.8	2.8	2.4	3.0	2.6	1.5	2.1
Age at first live birth	4.4	7.9	15.3	-3.1	-3.4	-2.8	-3.4	-3.0	-2.8	-2.1	-2.5	-0.9	-2.2	1.4	-3.4	-2.9	-3.9	-3.1	-0.6	-3.0	-3.4
Breast Cancer	4.2	10.2	21.7	4.3	3.4	2.1	4.0	3.7	4.0	1.7	2.8	1.4	1.4	-2.4	4.0	1.6	4.7	4.0	-1.6	2.4	4.2
Depressed Affect (Nagel 2018)	4.1	8.5	16.0	3.7	4.0	2.6	3.8	2.9	3.5	2.9	1.2	2.0	1.2	-1.4	3.5	2.9	3.9	3.6	0.7	1.3	3.7
Fed-up feelings	4.1	7.5	16.0	3.7	4.0	2.4	3.6	2.6	3.6	2.7	1.1	1.9	0.7	-1.1	3.0	3.1	2.6	3.7	1.0	0.7	3.6
Depression (Nagel 2018)	3.8	5.7	13.5	2.6	2.0	2.1	2.3	1.8	2.3	3.6	2.3	1.6	2.1	-1.0	3.5	2.8	3.7	2.6	1.3	1.2	2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	3.8	5.0	12.8	2.0	1.9	2.0	1.9	2.0	1.5	2.8	3.0	1.1	3.0	-1.2	3.3	2.4	3.6	2.1	1.4	2.0	1.1
Primary Biliary Cirrhosis	3.7	5.2	10.1	-3.0	-2.7	-2.0	-3.1	-2.4	-3.0	-2.2	-0.8	-2.0	-0.9	1.0	-2.4	-3.2	-1.8	-3.0	-1.4	-1.1	-2.6
Loneliness, isolation	3.7	5.1	10.2	2.4	2.8	3.2	2.0	0.7	2.6	2.4	1.0	3.1	1.6	1.1	2.7	2.2	3.2	2.8	0.5	1.1	2.5
Ever had prostate specific antigen (PSA) test	3.7	4.2	9.9	2.5	2.1	1.4	3.1	3.1	2.2	0.7	1.4	0.3	0.9	-2.1	1.9	1.9	2.1	2.2	0.5	2.7	2.7
Medication for pain relief, constipation, heartburn	3.6	6.2	16.5	-3.3	-2.5	-0.9	-4.1	-3.9	-3.2	-0.3	-0.8	-0.7	0.7	2.9	-1.7	-3.2	-1.3	-2.8	-1.4	-1.1	-4.0
Medication: Co-codamol	3.5	4.1	8.8	1.9	2.9	3.0	1.8	0.6	2.2	2.6	1.7	2.6	1.5	1.0	2.5	1.0	1.5	2.3	0.3	2.0	2.4
Frequency of tiredness / lethargy in last 2 weeks	3.5	5.7	13.9	2.2	2.4	2.4	2.0	1.6	2.1	3.7	2.3	1.8	3.0	-0.8	3.5	2.1	3.1	2.5	1.2	2.2	2.1
Irritability	3.2	5.4	14.3	3.5	3.0	1.2	3.8	3.1	3.4	0.4	-0.2	1.5	-0.9	-1.9	1.4	2.6	0.6	3.1	1.2	-0.2	3.4
Ever had hysterectomy (womb removed)	3.1	3.6	8.4	2.2	2.5	1.9	2.0	1.5	2.2	1.9	1.9	1.7	1.2	-0.3	2.9	0.8	2.0	2.4	0.7	1.6	2.3
Mouth/teeth dental problems: Dentures	3.1	5.3	14.0	1.7	2.4	2.1	2.2	1.6	1.7	3.7	2.0	0.8	2.2	-0.9	2.5	2.4	3.1	1.8	1.9	3.7	2.4
Alcohol drinker status: Previous	3.1	3.5	6.5	2.1	2.2	2.4	1.4	1.2	2.1	1.9	2.2	1.9	2.3	0.0	2.5	2.2	1.3	2.3	1.7	0.5	1.3
Serious illness, injury or assault to yourself	3.0	3.7	14.3	0.8	1.5	2.6	0.4	0.1	0.9	0.2	3.8	1.9	2.6	1.2	2.8	0.4	2.6	1.2	1.2	3.3	0.5
Noisy workplace	3.0	3.7	10.5	2.4	1.9	0.2	3.0	3.2	1.8	-0.2	0.7	-0.4	-0.1	-2.8	0.9	3.0	1.4	2.0	1.4	0.8	2.6
Qualifications: CSEs or equivalent	2.9	3.8	8.1	2.9	2.7	1.9	2.7	2.0	2.8	1.5	0.8	1.4	0.5	-0.6	2.0	1.7	1.6	2.8	0.6	-0.1	2.7
Mouth/teeth dental problems	2.8	4.3	16.6	-1.8	-1.6	-0.4	-2.1	-2.7	-1.3	-3.2	-1.1	1.3	-1.4	2.8	-1.7	-3.0	-4.1	-1.4	-0.5	-1.6	-1.4
Medication: Cholesterol lowering	2.8	4.3	9.9	2.9	2.3	1.7	2.8	2.3	2.7	1.9	0.5	1.3	0.5	-1.1	1.9	3.0	0.4	2.8	1.5	0.2	3.2
Taking other prescription medications	2.7	4.2	13.6	2.7	2.6	0.7	3.2	3.0	2.5	2.0	-1.0	0.2	-1.0	-2.3	0.7	2.1	0.4	2.3	0.2	0.1	3.7
Type 2 Diabetes (T2D) (2018)	2.5	4.7	9.2	1.9	2.9	2.9	2.1	1.7	2.1	3.0	1.9	2.3	1.7	-0.1	2.1	2.5	1.3	2.1	0.9	2.5	2.7
Trunk fat percentage	2.5	10.0	29.7	4.1	4.3	2.3	4.3	3.2	3.8	5.5	-0.8	1.7	-0.4	-1.7	1.6	3.6	0.0	3.9	0.2	0.3	5.4
Qualifications: A levels/AS levels or equivalent	2.5	5.6	12.1	-3.4	-2.6	-1.3	-3.5	-3.2	-3.1	-1.3	-0.5	-0.8	-0.7	2.3	-2.1	-3.0	-2.1	-3.2	-1.6	0.2	-3.1
Pack years of smoking	2.5	3.7	12.4	1.5	1.0	1.3	1.9	2.0	0.8	3.5	2.0	0.5	2.6	-2.0	2.3	2.7	1.9	1.3	1.7	1.5	1.5
Coronary Artery Disease (CAD)	2.4	2.8	5.6	2.0	2.2	1.9	2.0	1.3	1.9	0.9	1.1	1.2	1.4	-0.2	2.2	1.3	1.2	2.2	1.2	2.4	2.0
Qualifications: O levels/GCSEs or equivalent	2.4	3.8	10.1	-2.5	-2.0	-0.1	-2.8	-2.7	-2.2	-2.8	0.9	0.1	0.4	2.6	-0.7	-2.4	-0.7	-2.1	-1.1	0.1	-3.2
Body fat percentage	2.4	9.3	31.4	3.8	4.0	2.0	4.1	3.3	3.4	5.6	-0.9	1.3	-0.4	-2.1	1.4	3.6	0.2	3.5	-0.0	0.4	5.2
Overall health rating	2.4	5.1	14.7	2.2	2.1	2.1	2.0	1.7	1.9	3.8	2.1	1.2	2.5	-1.1	3.2	3.0	1.8	2.4	2.6	1.6	1.8
Mood swings	2.4	4.3	9.8	2.5	2.6	2.3	2.3	1.6	2.3	1.9	1.8	1.5	2.0	-0.4	3.1	2.0	2.4	2.6	1.1	0.7	2.1
Back pain experienced in last month	2.4	3.5	8.7	2.6	2.2	0.9	2.7	2.6	2.4	1.9	0.3	0.7	0.1	-1.9	1.6	2.1	0.3	2.4	1.1	0.1	2.9
Alzheimer’s Disease (including proxy)	2.3	3.3	10.2	-2.0	-1.3	-0.8	-2.1	-2.1	-1.7	-1.2	-2.1	0.3	-0.6	1.6	-2.3	-0.6	-2.5	-1.8	-0.2	-3.2	-2.6
Neuroticism score	2.3	4.7	10.1	2.5	3.2	2.8	2.2	0.9	2.5	2.5	1.4	2.0	1.5	0.5	3.0	1.5	2.6	2.9	0.6	1.0	2.4
Age at last live birth	2.3	3.3	7.9	-1.7	-2.8	-2.7	-2.0	-1.0	-1.7	-2.1	-0.9	-1.3	-1.3	-0.5	-1.9	-1.1	-2.2	-1.9	0.4	-2.2	-2.6
Commuting to job workplace: Car/motor vehicle	2.3	2.7	6.4	2.1	1.8	1.2	2.3	2.1	2.4	1.3	0.8	2.0	-0.2	-1.0	1.1	1.8	0.6	1.9	0.5	0.8	2.5
Miserableness	2.3	3.9	11.0	1.8	2.4	2.1	1.6	1.2	1.6	3.0	1.8	1.0	2.4	-0.3	3.2	1.5	3.3	2.0	0.6	1.6	1.3
Diabetes (mother)	2.2	2.8	10.0	1.6	1.1	0.5	1.9	2.0	1.5	2.0	1.5	0.8	1.6	-2.0	1.7	2.2	0.9	1.6	3.2	0.1	1.3
Medication: Gliclazide	2.2	2.5	6.0	2.1	1.5	1.5	1.8	1.5	1.9	0.9	1.7	0.9	0.6	-0.5	1.7	2.1	0.4	2.1	2.5	0.6	1.8
Medication: Bendroflumethiazide	2.2	3.3	11.4	1.0	1.2	2.7	0.7	0.1	1.0	3.4	2.1	1.7	2.9	0.8	2.4	1.0	2.5	1.5	0.4	2.2	0.7
Pack years adult smoking proportion	2.1	3.2	10.6	1.5	0.8	0.9	1.9	2.1	0.8	3.3	1.5	0.1	2.3	-2.2	1.9	2.7	1.8	1.3	1.6	0.9	1.3
Father’s age at death	2.1	2.9	7.9	-1.1	-1.5	-2.8	-0.8	0.3	-1.3	-2.8	-1.4	-2.8	-2.4	-1.5	-2.0	-1.2	-0.9	-1.4	-0.9	-1.4	-1.3
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.7	6.5	2.0	1.6	0.8	2.5	2.5	2.1	0.5	0.6	1.0	-0.0	-1.7	1.1	2.5	1.4	1.8	1.5	0.6	2.4
Commuting to job workplace: Public transport	2.1	2.5	6.5	-2.2	-1.4	0.0	-2.2	-2.3	-2.1	-0.2	0.4	-0.5	0.9	1.8	-0.4	-2.5	-0.4	-1.7	-1.9	1.3	-1.9
Worrier / anxious feelings	2.0	3.8	6.9	2.4	2.4	2.5	2.5	1.7	2.1	1.9	1.6	1.5	2.1	-0.5	2.4	1.8	1.6	2.6	0.6	1.1	2.0
Mouth/teeth dental problems: Bleeding gums	2.0	2.6	6.7	2.3	1.4	0.2	2.0	2.6	1.9	1.0	0.8	-0.6	0.0	-2.2	1.5	1.8	2.2	1.9	-0.6	-0.4	2.0
Number of full brothers	2.0	2.6	8.2	-2.1	-1.6	-1.2	-2.0	-1.5	-2.0	-2.3	0.1	-0.5	-0.0	0.7	-1.5	-1.1	-1.0	-2.1	1.2	-1.9	-2.9
Diabetes diagnosed by doctor	2.0	3.2	6.6	1.3	1.7	2.5	1.6	1.2	1.6	2.4	1.7	2.2	1.6	0.1	1.4	2.4	0.8	1.4	1.2	2.5	2.6
Neuroticism (2016)	1.9	2.8	6.2	2.0	2.3	1.2	2.5	2.3	1.8	1.6	0.8	1.2	0.5	-1.4	2.2	1.1	1.2	2.1	-0.2	0.8	2.2
Impedance of leg (left)	1.9	9.2	26.3	3.5	1.6	-1.9	4.0	5.1	2.8	-4.8	-1.9	-1.9	-3.4	-4.9	-1.4	2.6	-1.1	2.3	1.0	-3.2	2.3
Migraine (self-reported)	1.9	2.3	7.5	1.4	0.1	-0.1	2.0	2.6	1.2	0.7	1.5	-0.2	1.4	-2.7	1.7	1.3	1.9	1.2	1.2	1.8	1.2
Medication: Aspirin	1.9	2.5	6.0	2.3	1.2	0.1	2.4	2.5	2.0	0.5	0.3	-0.3	-0.7	-2.1	1.2	2.3	1.0	1.9	0.9	0.2	2.4
Neuroticism (Nagel 2018)	1.8	4.3	8.1	2.8	2.6	1.9	2.7	1.9	2.8	2.1	0.7	1.7	0.6	-0.9	2.6	2.3	2.2	2.8	0.4	0.3	2.5
Smoking Status	1.8	4.3	11.8	2.1	1.8	0.7	2.7	2.8	1.4	3.4	0.2	-0.8	1.8	-2.6	1.9	2.6	3.3	1.8	0.5	1.1	1.9
Chronotype (morning person)	1.8	4.2	12.7	2.5	1.9	0.9	3.3	3.6	2.3	0.8	1.0	1.1	1.6	-3.0	1.4	2.5	1.1	2.1	1.9	0.6	2.1
Maternal smoking around birth	1.8	2.5	15.3	1.2	0.8	1.6	1.3	0.9	0.7	3.9	1.6	0.4	2.8	-0.5	2.4	1.0	1.0	1.4	0.4	1.1	1.1
Heart attack	1.8	2.3	7.6	2.0	1.1	1.2	2.1	1.9	1.7	-0.4	1.0	0.6	0.6	-1.1	1.4	2.3	-0.1	1.9	0.9	1.3	2.8
Diabetes (self-reported)	1.8	2.7	6.5	1.4	1.5	2.3	1.3	0.9	1.7	2.5	1.2	2.1	1.4	0.4	1.3	2.6	0.7	1.5	1.1	1.7	2.2
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	7.4	-2.5	-1.7	-1.1	-2.3	-1.6	-2.3	-2.1	0.5	-0.9	0.0	0.8	-1.1	-2.7	0.3	-2.3	-1.5	0.7	-2.6
Medication: Aspirin	1.8	2.4	5.7	2.2	1.4	0.8	2.1	2.1	1.9	0.7	0.8	0.3	-0.1	-1.5	1.6	2.4	1.0	1.9	0.8	0.4	2.3
Arm fat percentage (right)	1.7	6.7	35.6	2.8	3.4	2.2	3.0	2.0	2.6	6.0	-0.1	1.6	0.4	-1.0	1.8	2.5	1.0	2.8	-0.7	0.9	4.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.6	19.7	1.5	-0.1	-2.8	2.7	3.9	0.6	-3.5	-0.9	-3.2	-3.3	-4.4	-1.5	-0.5	-1.2	0.4	-2.2	-1.2	1.8
Qualifications: College or University degree	1.7	5.2	9.8	-2.7	-2.2	-1.9	-3.0	-2.8	-2.2	-2.5	-1.6	-0.8	-1.8	1.8	-2.8	-2.4	-3.1	-2.6	-1.1	-1.5	-2.7
Medication: Blood pressure	1.7	3.0	8.0	2.4	1.4	1.1	2.3	1.5	2.3	2.3	-0.4	1.1	0.0	-0.8	1.2	2.6	-0.5	2.2	1.7	-0.8	2.8
Medication: Ibuprofen	1.7	2.0	5.8	1.6	1.0	-0.2	2.3	2.4	1.6	-0.3	-0.6	-0.0	-1.1	-2.1	0.1	2.1	0.7	1.2	1.0	-0.4	2.2
Medication: Seretide 50 evohaler	1.7	1.9	4.4	1.3	1.6	1.1	1.2	1.0	1.1	2.1	1.5	0.4	1.1	-0.7	1.6	2.0	1.8	1.3	0.3	1.9	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.5	17.5	1.6	-0.5	-1.9	2.4	4.0	0.5	-1.9	0.6	-2.6	-1.5	-4.2	-0.2	0.0	0.2	0.7	-1.5	-0.3	1.4
Number of self-reported non-cancer illnesses	1.7	2.9	9.0	1.8	1.3	-0.3	2.6	2.9	1.4	1.1	-1.1	-1.2	-0.7	-3.0	0.3	2.4	-0.5	1.3	0.1	0.7	2.9
Leg fat percentage (left)	1.7	6.2	31.8	2.7	3.1	1.3	3.1	2.5	2.3	5.6	-1.5	0.6	-0.4	-1.9	0.5	3.2	0.3	2.4	-0.7	0.4	4.1
Age started oral contraceptive pill	1.7	2.1	4.1	-1.9	-2.0	-1.0	-1.8	-1.4	-1.9	-1.8	0.1	-1.1	-0.2	0.8	-1.1	-1.8	-1.9	-1.8	-0.9	1.3	-1.6
Impedance of whole body	1.7	8.9	25.1	3.9	1.9	-1.4	4.2	5.0	3.3	-4.7	-1.0	-1.5	-3.1	-4.5	-0.6	2.1	-0.7	2.9	1.1	-2.9	2.7
Lung FVC	1.6	8.0	31.7	3.3	-0.1	-1.0	4.2	5.6	1.8	-2.3	3.2	-2.3	-0.1	-5.4	2.6	0.1	2.9	2.4	-1.1	1.2	2.4
Sensitivity / hurt feelings	1.6	2.7	5.4	1.7	1.8	2.3	1.4	0.3	1.9	1.3	1.7	1.9	0.7	1.1	2.3	0.3	2.1	2.0	-0.9	1.8	2.0
Impedance of leg (right)	1.6	7.8	27.4	2.8	0.8	-2.2	3.4	4.7	2.2	-5.2	-1.2	-2.1	-3.1	-4.8	-1.5	1.9	-1.6	1.7	1.2	-3.0	1.5
Depression (self-reported)	1.6	1.9	4.5	1.9	1.7	1.0	1.5	1.3	1.5	1.8	0.5	0.5	0.9	-0.7	1.8	2.1	1.1	1.9	1.3	-0.2	1.0
Hair/balding pattern: Pattern 4	1.6	3.8	9.6	-2.8	-2.6	-1.6	-3.1	-2.8	-2.9	1.2	-1.2	-1.3	0.3	1.1	-1.6	-0.5	-1.1	-2.7	0.0	-0.7	-2.7
Arm fat percentage (left)	1.6	6.6	37.6	2.8	3.3	2.2	2.9	1.9	2.6	6.1	-0.2	1.7	0.4	-0.9	1.7	2.4	0.7	2.8	-0.4	0.6	4.2
Neuroticism	1.5	3.6	7.8	2.5	2.8	2.0	2.2	1.5	2.3	2.4	0.7	1.2	0.6	-0.3	2.4	1.8	2.3	2.5	0.5	0.3	2.3
Average weekly fortified wine intake	1.5	1.7	3.3	-1.7	-1.0	-0.9	-1.7	-1.8	-1.5	-0.9	-1.4	-0.5	-0.9	1.1	-1.7	-1.4	-1.5	-1.5	-1.0	-1.1	-1.2
Trunk fat mass	1.5	6.6	31.1	2.9	3.5	2.0	3.0	1.9	2.8	5.6	-1.2	1.6	-0.4	-0.8	1.1	2.8	-0.6	2.8	0.0	0.3	4.5
Leg fat percentage (right)	1.5	5.4	27.9	2.5	2.6	1.1	2.9	2.5	2.1	5.3	-1.1	0.5	-0.3	-2.1	0.5	3.0	-0.1	2.2	-0.2	0.5	3.8
Qualifications: nursing, teaching	1.5	2.4	6.2	-2.3	-1.7	-0.0	-2.4	-2.2	-1.8	-0.6	0.6	0.8	0.5	2.1	-0.4	-1.8	-1.1	-2.1	-0.3	0.5	-2.5
Heart attack/myocardial infarction (self-reported)	1.5	2.0	6.3	1.8	1.0	1.2	1.9	1.7	1.5	-0.5	0.9	0.5	0.6	-1.0	1.4	2.1	0.1	1.7	0.8	1.4	2.5
Deep venous thrombosis (DVT) (self-reported)	1.5	1.9	8.6	1.5	0.6	1.0	1.2	1.7	1.3	0.4	2.9	0.6	1.8	-1.3	2.1	1.0	1.1	1.5	0.2	0.6	0.7
Crohns Disease (2012)	1.4	2.3	5.2	-1.4	-1.6	-2.3	-1.2	-0.6	-1.5	-1.4	-2.2	-2.3	-2.0	-0.5	-1.9	-0.6	-1.1	-1.8	-0.8	-0.7	-1.3
Systolic blood pressure, automated reading	1.4	4.2	15.6	0.7	1.0	-1.9	2.0	2.2	0.3	-0.6	-3.9	-2.7	-3.7	-2.6	-2.6	0.5	-0.8	-0.1	-1.6	-1.2	2.5
Medication: Metformin	1.4	2.0	4.8	1.8	1.7	1.6	1.7	1.6	1.8	1.3	0.4	1.0	0.2	-0.3	0.9	2.2	0.7	1.8	1.0	1.0	2.0
Prospective memory result	1.4	1.7	4.5	1.2	1.2	1.9	0.9	0.5	1.4	1.2	1.3	2.0	1.3	0.7	2.1	0.3	0.9	1.3	1.2	1.0	1.4
Pulse wave reflection index	1.4	1.7	5.0	0.9	0.8	2.0	0.1	-1.0	1.3	1.5	1.1	2.0	1.2	2.2	2.0	0.3	1.0	1.3	1.1	1.0	0.7
Glaucoma (self-reported)	1.4	1.6	5.4	1.6	0.8	-0.4	1.6	2.1	1.1	0.5	1.3	-0.9	0.1	-2.3	1.3	1.0	0.7	1.2	-0.2	1.5	1.5
Mouth/teeth dental problems: Loose teeth	1.4	1.6	11.5	1.0	0.2	-0.5	1.0	1.5	0.5	3.4	-0.6	-1.3	0.4	-1.9	1.0	1.0	2.0	0.8	-0.1	-0.8	0.3
Whole body fat mass	1.4	5.7	32.2	2.5	3.1	1.8	2.7	1.7	2.4	5.7	-1.0	1.5	-0.1	-0.8	1.0	2.6	-0.6	2.4	-0.0	0.5	4.1
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	8.2	-1.2	-1.8	-2.1	-1.3	-0.5	-1.4	-1.1	-1.1	-2.0	-0.4	-0.8	-1.4	0.4	0.2	-1.3	0.4	-2.9	-2.8
Myopia	1.4	2.0	5.8	-1.5	-1.3	-0.5	-1.8	-2.2	-1.4	-1.6	-1.2	-0.5	-0.9	1.8	-1.0	-2.4	-1.6	-1.4	-0.9	-0.3	-0.8
Leg fat mass (left)	1.4	5.3	36.7	2.1	2.8	1.5	2.4	1.5	2.0	6.1	-1.5	1.1	-0.1	-0.9	0.6	2.9	-0.4	2.0	-0.3	0.5	3.9
Schizophrenia vs Biploar Disorder	1.3	1.7	4.3	-1.7	-0.2	0.8	-1.9	-2.1	-1.5	1.3	-0.2	0.4	1.4	2.1	-0.4	-0.9	0.2	-1.3	-1.0	1.3	-1.7
Fasting Glucose	1.3	1.6	3.9	1.7	0.7	0.4	1.8	2.0	1.3	0.1	1.6	-0.2	0.9	-1.7	1.3	1.8	1.2	1.5	0.6	0.4	1.0
Number of treatments/medications taken	1.3	2.4	7.7	1.9	1.7	1.0	2.4	2.0	1.8	1.1	-0.1	0.7	-0.3	-1.3	1.0	2.4	-0.1	1.6	0.9	1.0	2.8
High blood pressure	1.3	3.5	11.1	2.4	1.9	0.6	2.9	2.5	2.2	2.1	-1.7	0.3	-0.9	-1.9	0.2	2.3	-1.2	2.1	0.3	-0.2	3.3
Medication: Simvastatin	1.3	1.9	4.9	1.8	1.6	1.4	1.9	1.6	1.5	1.0	0.5	0.6	0.9	-0.8	1.2	2.2	0.5	1.7	0.9	0.9	2.2
Impedance of arm (right)	1.3	6.2	19.6	3.3	1.7	-0.9	3.6	4.1	2.8	-4.4	-0.0	-0.9	-2.5	-3.5	0.0	1.3	-0.1	2.6	0.6	-2.2	2.4
Forced expiratory volume in 1-second (FEV1)	1.3	4.3	14.2	2.1	0.1	-1.9	3.0	3.7	1.4	-3.0	-0.5	-1.9	-2.6	-3.8	-0.6	-0.3	-1.2	1.3	-1.0	-1.6	1.8
Exposure to tobacco smoke at home	1.3	1.4	4.8	-1.6	-0.4	-0.0	-1.4	-1.4	-1.7	0.1	0.1	-0.6	0.4	1.0	-0.4	-1.2	1.4	-1.6	-2.2	1.7	-0.8
Blood clot in the leg (DVT)	1.3	1.7	6.3	1.5	0.8	1.0	1.4	1.8	1.4	0.2	2.5	0.6	1.5	-1.3	1.9	1.2	0.9	1.5	0.2	0.5	1.0
Had major operations	1.3	1.5	3.9	1.4	1.3	0.9	1.3	0.8	1.7	0.5	0.7	2.0	0.5	-0.2	1.7	1.0	0.9	1.5	1.4	1.3	1.4
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	11.2	-0.8	-0.6	-1.6	-0.8	-0.9	-0.6	-3.3	-2.2	-1.1	-2.8	0.6	-2.1	-0.9	-2.6	-1.0	0.0	-2.5	-0.5
Basal cell carcinoma (self-reported)	1.3	1.6	6.3	1.5	0.8	-0.7	1.9	2.1	1.0	0.4	-0.0	-1.3	0.0	-2.5	0.3	1.8	0.2	1.2	0.7	0.0	1.5
Mean Putamen Volume	1.2	1.4	5.4	0.9	0.5	0.2	2.0	2.3	0.7	1.6	-0.2	0.4	0.4	-2.2	0.4	1.4	-0.1	0.6	-0.3	0.9	1.6
Relative age voice broke	1.2	1.9	6.5	-1.3	-1.2	-0.9	-1.3	-1.5	-1.2	-1.7	-0.9	-1.5	-1.5	1.1	-1.4	-2.5	-0.6	-1.1	-2.2	0.3	-0.7
Medication: Atenolol	1.2	1.5	3.3	1.7	1.7	1.5	1.4	0.8	1.6	1.2	0.2	1.0	0.3	0.2	1.4	1.3	0.0	1.8	0.2	0.9	1.8
Waist circumference	1.2	4.3	29.5	1.6	2.8	2.2	1.7	0.7	1.8	5.4	-0.5	2.1	0.7	0.3	1.3	2.4	-0.1	1.8	0.0	0.8	3.0
Impedance of arm (left)	1.2	5.5	15.5	3.3	1.5	-0.9	3.3	3.6	2.9	-3.9	-0.6	-0.9	-2.8	-3.0	-0.1	1.0	-0.6	2.6	0.7	-2.5	2.4
Forced vital capacity (FVC), Best measure	1.2	4.4	14.3	1.2	-0.4	-2.8	2.2	3.1	0.6	-3.0	-1.1	-2.9	-3.4	-3.8	-1.4	-0.5	-1.2	0.2	-1.7	-1.0	1.8
Comparative body size at age 10	1.2	3.4	17.6	-0.6	0.4	2.2	-1.7	-3.3	0.3	2.9	0.2	3.1	1.0	4.2	1.0	-0.9	-0.3	0.1	1.7	-0.2	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	2.5	-1.3	-1.4	-1.5	-1.1	-1.0	-1.5	-0.2	-1.1	-1.5	-1.0	-0.1	-1.6	-1.2	-1.4	-1.6	-1.3	-1.4	-1.1
Shortness of breath walking on level ground	1.2	1.4	4.2	1.2	1.3	1.6	0.5	-0.6	1.5	-0.6	0.8	2.0	-0.0	1.8	1.5	0.1	-1.0	1.6	1.5	0.2	1.0
Eye problems/disorders: None of the above	1.2	1.4	8.2	-0.5	0.8	1.8	-0.9	-1.9	0.1	0.5	0.3	2.1	0.5	2.9	0.0	-1.2	-0.9	-0.0	-0.4	0.0	-0.1
Leg fat mass (right)	1.2	4.7	32.7	2.0	2.5	1.2	2.3	1.6	1.9	5.7	-1.4	0.9	-0.2	-1.2	0.5	2.8	-0.7	1.9	0.0	0.2	3.6
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	6.6	-0.5	-0.8	-0.8	-0.5	-0.8	-0.4	-0.5	-1.9	-0.0	-1.9	0.7	-1.5	-1.7	-1.0	-0.8	-2.6	-1.6	0.1
Guilty feelings	1.2	1.8	4.0	1.3	1.3	1.8	0.9	-0.5	1.7	1.6	0.9	2.0	0.7	1.4	1.9	0.6	0.9	1.7	1.2	0.9	1.3
Number of operations (self-reported)	1.2	1.8	4.8	0.9	0.8	1.2	0.7	0.5	1.1	1.1	1.7	1.6	1.9	-0.1	2.2	1.4	1.7	1.2	1.6	1.6	0.3
Vascular/heart problems diagnosed by doctor	1.2	3.3	10.7	-2.3	-2.0	-0.4	-2.9	-2.7	-2.0	-1.3	1.6	0.4	1.1	2.2	0.0	-2.4	0.9	-1.8	0.1	0.0	-3.3
Supplements: Calcium	1.2	1.4	6.1	-0.7	-0.5	1.0	-1.1	-1.2	-0.6	-1.7	2.5	0.9	1.2	1.8	1.2	-0.8	1.0	-0.1	-0.0	0.9	-1.4
Waist Hip Ratio (WHR)	1.1	5.0	11.7	3.2	2.9	1.3	3.4	3.2	3.2	-0.2	0.2	1.1	-0.6	-1.9	1.0	3.4	1.2	2.9	1.4	-0.6	2.5
Lung FEV1/FVC ratio	1.1	5.8	17.7	3.0	3.2	1.6	4.0	4.2	2.6	0.5	2.0	0.6	0.8	-2.6	2.0	0.8	2.4	2.7	-1.4	1.6	2.8
Multivitamins +/- minerals	1.1	1.4	5.8	-0.4	-0.2	1.6	-1.0	-1.6	0.1	0.0	1.9	1.8	1.2	2.4	1.3	-0.9	0.4	0.1	0.2	1.0	-0.7
Body mass index (BMI)	1.1	4.6	45.7	1.0	2.2	2.3	1.1	0.0	1.1	6.8	-0.2	1.8	1.4	0.6	1.5	1.7	0.7	1.4	-0.7	1.8	2.6
Arm fat mass (right)	1.1	4.4	35.6	1.7	2.5	1.9	1.9	0.8	1.6	6.0	-0.7	1.6	0.4	-0.1	1.1	1.8	-0.0	1.8	-0.6	0.9	3.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	4.1	1.3	1.0	0.5	1.7	2.0	0.8	1.3	1.0	-0.6	1.2	-1.9	1.3	1.6	1.2	1.1	-0.2	1.7	1.0
Headache pain in last month	1.1	1.8	5.0	1.5	0.9	0.2	1.8	2.1	1.3	0.6	1.6	0.1	0.5	-2.0	1.5	1.3	2.2	1.2	-0.0	1.1	1.3
Gout (self-reported)	1.1	1.5	5.5	0.5	0.7	-1.5	1.1	1.3	0.6	-0.7	-1.8	-0.7	-2.3	-1.7	-1.5	0.2	-1.6	0.0	-0.1	-1.4	1.2
Supplements: Vitamin C	1.1	1.3	3.3	1.5	0.8	0.6	1.6	1.3	1.7	0.1	0.5	1.2	0.1	-0.9	0.8	1.8	0.6	1.5	0.6	0.8	1.8
Hypertension (Self-reported)	1.1	2.9	8.9	2.1	1.6	0.5	2.6	2.2	1.9	2.5	-1.5	0.2	-0.6	-1.8	0.3	2.3	-0.8	1.7	0.5	-0.1	3.0
Eye problems/disorders: Glaucoma	1.1	1.3	5.2	1.1	0.7	-0.4	1.4	2.0	0.8	0.7	1.1	-0.6	0.4	-2.3	0.9	1.4	1.0	0.8	-0.0	1.4	1.1
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	4.9	1.4	2.0	0.2	2.2	1.8	1.4	0.0	-0.7	0.5	-0.9	-1.5	0.0	0.6	-0.4	1.1	0.6	0.2	1.7
Prostate Cancer	1.0	1.4	8.5	1.2	0.4	-0.7	1.5	2.0	0.8	-2.9	0.4	-0.9	-0.6	-2.0	0.1	0.9	-0.2	0.8	0.6	-0.6	0.4
Triglycerides	1.0	1.6	3.3	1.4	1.4	0.9	1.8	1.4	1.8	1.0	0.8	1.8	1.0	-0.6	1.3	1.0	0.5	1.7	0.0	1.2	1.5
Ulcerative Colitis	1.0	1.4	5.8	-0.2	0.2	1.8	-0.8	-1.5	-0.1	2.2	1.2	0.9	1.3	2.4	1.5	-0.4	0.4	0.3	0.0	1.3	0.2
Townsend deprivation index at recruitment	1.0	1.4	9.8	-0.5	-0.5	0.9	-0.4	-0.4	-0.7	1.4	1.9	0.1	3.1	0.1	1.6	0.6	1.3	-0.2	1.3	1.4	-0.5
Past tobacco smoking	1.0	1.9	4.9	-1.5	-1.5	-0.7	-2.0	-1.9	-1.2	-1.7	-0.2	0.1	-1.2	1.8	-1.2	-2.2	-1.4	-1.4	-0.6	-0.1	-1.2
Time employed in main current job	1.0	1.1	2.2	1.2	0.9	0.6	1.3	1.5	1.1	1.4	1.2	0.3	0.8	-1.1	1.3	0.8	1.1	1.1	0.7	1.0	0.9
Trunk predicted mass	1.0	5.5	18.8	-3.4	-1.8	-0.5	-3.4	-4.3	-2.5	1.5	-1.7	0.6	-0.6	3.5	-1.7	-2.2	-3.1	-2.9	-1.0	-0.0	-1.6
Birth weight	1.0	2.2	6.3	-1.6	-1.2	0.7	-1.9	-2.2	-1.3	-1.6	1.6	0.3	0.5	2.5	0.5	-2.3	1.2	-1.2	-1.2	1.3	-1.5
Chronic bronchitis/emphysema (mother)	1.0	1.2	4.2	-1.2	-1.4	-0.1	-1.2	-1.1	-1.4	-0.3	1.6	-0.1	1.6	0.5	0.4	-1.2	-0.3	-1.1	0.4	0.4	-2.0
Heart disease (mother)	1.0	1.3	3.5	1.3	0.9	1.2	1.2	0.8	1.3	1.5	0.6	1.1	0.5	-0.3	1.5	0.8	0.7	1.4	-0.3	1.4	1.9
Number of full sisters	1.0	1.2	3.3	-1.2	-1.8	-0.7	-1.2	-0.4	-1.4	-1.6	0.1	-0.9	0.1	0.1	-0.3	-1.4	-0.5	-1.0	-1.0	-1.5	-1.5
Suffer from ‘nerves’	1.0	1.6	4.5	-1.6	-1.3	-0.7	-2.0	-2.0	-1.6	0.1	-0.6	-0.8	0.2	1.2	-0.7	-1.7	-0.7	-1.4	-0.3	-1.0	-2.1
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	3.5	1.1	-0.0	1.2	0.9	0.9	1.0	0.6	1.9	0.9	1.5	-0.3	1.8	0.9	1.3	1.1	1.3	0.2	0.2
Illnesses of father: None of the above (group 1)	1.0	1.3	5.9	1.0	1.2	-0.7	1.6	1.7	1.2	-2.4	-0.8	-0.2	-1.7	-1.2	-0.5	0.5	0.4	0.7	0.6	0.3	1.0
Arm fat mass (left)	1.0	4.0	35.4	1.6	2.4	1.7	1.7	0.6	1.6	6.0	-1.0	1.5	0.2	-0.0	0.9	1.7	-0.4	1.7	-0.6	0.3	3.2
Tinnitus: Yes, now most or all of the time	1.0	1.2	2.8	0.6	0.7	1.7	0.0	-0.4	0.6	1.4	1.2	1.2	1.5	1.3	1.7	0.7	0.9	1.0	0.7	1.5	0.5
Illnesses of father: High blood pressure	1.0	1.2	3.3	-1.6	-1.1	0.0	-1.5	-1.6	-1.6	0.7	0.1	-0.6	1.0	1.1	-0.1	-1.5	0.1	-1.2	-1.8	0.8	-0.9
Unable to work because of sickness or disability	1.0	1.3	4.9	1.4	0.4	0.7	1.2	0.9	1.1	0.3	1.5	-0.0	1.2	-0.7	2.2	0.8	1.6	1.5	1.6	0.5	0.6
Age when periods started (menarche)	0.9	2.2	9.0	-1.0	-1.9	-1.0	-1.3	-0.3	-1.3	-3.0	2.8	-0.5	1.1	-0.4	0.4	-1.7	0.5	-1.0	1.2	-0.4	-2.4
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	3.0	0.6	0.7	0.9	1.1	0.9	0.6	1.6	1.0	1.0	1.1	-0.7	1.4	0.2	1.7	0.6	-0.5	1.4	0.9
Chronic bronchitis/emphysema (father)	0.9	1.1	7.0	0.5	0.7	1.4	0.2	-0.8	0.6	2.6	0.1	1.4	0.7	1.3	1.3	0.6	0.5	0.9	-0.0	0.3	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.3	3.3	1.3	1.4	0.9	1.4	0.8	1.2	1.7	0.2	0.4	0.6	-0.6	1.2	0.7	1.8	1.4	-0.8	1.4	1.6
Forced vital capacity (FVC)	0.9	3.4	11.0	1.7	-0.4	-2.1	2.4	3.0	1.1	-2.9	-0.9	-1.9	-2.6	-3.3	-0.7	-0.2	-1.4	0.9	-0.6	-1.6	1.6
Qualifications: None of the above	0.9	2.0	5.0	1.3	1.5	0.1	2.0	2.0	0.8	1.7	-0.6	-0.7	0.4	-2.2	0.7	1.6	2.2	1.1	0.5	0.4	2.2
Trunk fat-free mass	0.9	5.3	18.0	-3.3	-1.7	-0.5	-3.4	-4.2	-2.5	1.5	-1.7	0.7	-0.6	3.4	-1.7	-2.1	-3.2	-2.8	-0.8	-0.0	-1.6
Peak expiratory flow (PEF)	0.9	2.2	9.8	1.8	1.1	-0.2	2.8	3.1	1.4	-1.1	0.8	-0.3	-0.5	-2.8	0.3	0.6	0.0	1.4	-0.5	-0.1	1.7
Neck or shoulder pain in last month	0.9	1.3	6.8	0.7	-0.0	-1.2	1.6	2.2	0.1	-0.7	-0.3	-1.4	-1.2	-2.6	-0.6	0.2	0.9	0.2	-1.6	-0.1	0.8
Medication: Omeprazole	0.9	1.0	3.1	1.0	1.8	0.1	1.6	1.1	1.2	-0.1	-1.3	0.6	-1.2	-0.8	-0.5	0.5	-1.2	0.7	0.6	-0.4	1.4
Knee pain experienced in last month	0.9	1.4	2.8	0.9	1.4	1.1	1.2	1.5	0.7	1.4	0.9	0.6	0.9	-0.9	1.1	1.6	1.7	1.0	-0.8	1.5	1.4
Illnesses of father: Heart disease	0.9	1.3	8.4	0.8	0.6	1.1	0.6	0.8	0.4	2.9	1.4	0.5	1.9	-0.6	1.7	0.1	0.3	0.8	0.6	0.8	0.8
Handedness (chirality/laterality): Left-handed	0.9	1.0	4.5	0.4	-0.2	1.0	-0.0	-0.1	0.3	0.1	2.0	0.6	2.1	0.3	1.7	-0.4	0.5	0.6	0.4	2.1	-0.0
Osteoporosis (self-reported)	0.9	1.1	5.4	0.0	-0.1	-1.4	0.5	1.2	-0.2	-2.3	-0.6	-1.7	-1.5	-1.4	-1.2	-0.6	0.1	-0.4	-0.7	-0.3	-0.4
Ever taken oral contraceptive pill	0.9	0.9	2.4	1.5	1.2	0.6	1.4	1.6	1.2	0.2	0.7	0.4	0.0	-0.8	0.8	1.3	0.6	1.3	0.4	-0.2	1.1
Pain experienced in last month	0.9	1.5	5.8	-1.4	-1.1	0.2	-1.9	-2.3	-1.2	-0.4	-0.7	0.1	-0.1	2.4	-1.2	-1.2	-1.1	-1.2	-0.7	-0.6	-1.2
Reaction Time	0.8	1.4	3.5	-1.2	-1.0	-0.7	-1.7	-1.9	-1.5	0.9	-1.2	-1.2	-0.3	1.2	-0.5	-1.6	0.4	-1.0	0.0	-1.8	-1.3
HDL Cholesterol	0.8	1.3	3.3	-1.5	-1.8	-0.1	-1.6	-1.6	-1.4	-1.2	0.2	-0.2	-0.0	1.3	-0.6	-1.2	-1.1	-1.2	0.8	-0.2	-1.6
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.8	1.3	1.0	0.1	1.1	1.2	1.1	0.1	0.2	-0.1	-0.0	-1.2	0.5	1.7	0.1	1.1	1.4	0.7	1.3
BMI	0.8	4.7	56.2	0.3	2.0	1.9	0.5	-0.6	0.4	7.5	-0.8	2.2	1.9	0.7	1.1	2.0	-0.3	0.8	0.4	0.6	1.8
Respiratory disease	0.8	1.7	3.4	-1.7	-1.2	-1.2	-1.8	-1.7	-1.8	1.4	-1.6	-1.5	-0.3	0.4	-1.2	-0.2	-0.9	-1.6	1.0	-0.9	-1.3
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	3.7	-1.2	-1.2	-0.3	-1.4	-1.7	-1.2	-0.9	-0.1	0.1	0.0	1.3	0.0	-1.9	-0.3	-1.0	0.8	0.4	-1.1
Supplements: Glucosamine	0.8	1.1	5.1	-0.8	-0.2	0.7	-1.1	-1.5	-0.3	-1.6	0.9	1.0	-0.1	2.2	0.1	-2.0	-0.1	-0.3	-0.9	0.5	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.8	5.6	0.3	0.8	2.4	0.3	-0.3	0.6	1.5	2.1	2.4	2.1	1.4	1.8	0.1	0.4	0.6	0.4	1.2	0.7
Exposure to tobacco smoke outside home	0.8	1.1	6.1	0.1	0.3	1.3	0.1	-0.1	0.2	0.3	2.0	1.2	1.5	0.6	1.3	-0.4	2.5	0.4	0.5	0.6	-0.2
Angina (self-reported)	0.8	1.0	5.9	-0.0	1.3	1.1	0.1	0.0	-0.0	0.8	1.0	0.4	0.9	0.4	0.8	-0.2	1.7	0.0	-1.8	2.4	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	3.0	0.9	1.7	0.8	1.7	1.1	1.0	0.7	-1.1	0.1	-0.7	-0.6	-0.6	0.2	-0.4	0.7	-1.0	0.5	1.7
Long-standing illness, disability or infirmity	0.8	1.3	4.7	1.3	0.1	-0.6	1.3	1.7	1.1	0.9	0.5	-0.6	0.0	-2.2	1.4	1.2	0.5	1.0	1.3	0.8	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	3.0	1.2	0.8	-0.2	1.5	1.7	0.8	-0.7	0.2	-0.8	-0.3	-1.6	0.0	1.6	0.7	0.8	-0.5	0.5	0.8
Wears glasses or contact lenses	0.8	0.9	3.0	1.2	0.3	0.1	1.3	1.7	0.6	-0.5	0.7	-0.6	0.4	-1.6	0.5	1.1	0.3	0.9	0.7	1.4	1.2
Hearing aid user	0.8	0.9	2.6	1.1	1.6	1.0	1.3	0.6	1.5	-0.5	-0.3	1.2	-0.7	0.5	0.5	0.3	-0.1	1.3	0.9	-0.2	1.2
Crohns Disease (2017)	0.7	1.4	5.2	-0.4	-1.0	-1.7	-0.6	-0.3	-0.4	-0.7	-2.1	-1.8	-2.3	-0.3	-1.4	0.1	-1.2	-0.8	-1.5	-0.9	-0.1
Systolic Blood Pressure	0.7	3.6	15.3	1.5	1.3	-1.3	2.2	2.2	1.2	-0.2	-3.9	-2.1	-3.2	-2.1	-1.8	1.8	-0.7	0.9	-0.5	-1.9	1.9
Average weekly spirits intake	0.7	0.9	4.3	0.3	0.7	1.6	0.3	-0.6	0.5	1.1	0.4	0.8	0.8	1.4	0.9	-0.1	0.7	0.6	-0.1	2.1	0.9
Angina	0.7	0.9	4.7	0.1	1.2	1.1	0.1	-0.0	0.1	0.8	0.8	0.4	0.8	0.5	0.8	-0.0	1.7	0.1	-1.6	2.2	0.7
Hayfever, allergic rhinitis or eczema	0.7	1.5	3.8	-1.1	-0.7	-1.4	-1.3	-0.4	-0.9	-1.9	-1.3	-0.7	-1.3	-0.1	-1.7	0.2	-1.8	-1.2	0.5	-1.5	-1.7
Hair/balding pattern: Pattern 2	0.7	0.9	3.5	0.3	1.1	-0.3	1.2	1.2	0.3	0.3	-0.7	-0.5	-1.1	-1.2	-1.1	-0.3	-1.9	-0.0	-1.0	0.1	1.8
Breastfed as a baby	0.7	0.8	2.9	1.3	0.5	0.6	1.2	0.8	1.2	0.9	0.1	0.8	0.1	-0.5	1.3	0.3	0.6	1.3	0.3	0.6	1.7
Tense / ‘highly strung’	0.7	1.2	2.9	1.6	1.1	0.3	1.7	1.5	1.3	1.0	-0.0	-0.0	-0.2	-1.2	0.6	1.4	0.0	1.5	-0.2	-0.9	1.4
Loud music exposure frequency	0.7	0.8	2.9	0.7	0.4	-1.1	0.8	1.2	0.2	-0.8	-1.2	-1.5	-0.9	-1.7	-0.4	0.6	-0.2	0.3	-0.0	-1.4	0.3
Medication: Paracetamol	0.7	1.1	5.8	0.4	0.3	-0.1	1.3	1.7	0.2	-0.1	1.1	-0.7	0.4	-2.0	0.4	1.1	0.9	0.1	0.1	2.4	1.1
Medication: Amlodipine	0.7	1.0	3.9	0.8	-0.6	-0.5	0.8	1.4	0.4	1.4	-0.3	-1.1	-0.0	-2.0	0.2	1.7	1.2	0.5	1.0	-0.5	1.0
Worry too long after embarrassment	0.7	1.2	5.2	-0.0	0.5	1.7	-0.5	-1.6	0.5	0.8	0.7	1.8	1.0	2.3	1.2	-0.8	0.8	0.5	-0.6	1.0	-0.1
Chest pain or discomfort	0.7	1.1	5.5	0.4	0.9	0.4	0.9	1.1	0.2	1.2	0.6	-0.5	1.0	-1.0	1.2	0.5	1.9	0.4	0.6	2.4	1.0
Whole body fat-free mass	0.7	4.0	14.4	-2.7	-1.1	-0.0	-2.8	-3.8	-2.0	2.6	-1.7	0.9	-0.2	3.2	-1.3	-1.5	-2.6	-2.2	-0.8	0.2	-0.9
Eye problems/disorders: Cataract	0.7	0.8	3.5	-0.3	-0.8	-1.0	0.1	0.7	-0.9	-0.7	0.3	-1.7	0.5	-1.5	0.5	-0.6	1.9	-0.5	0.2	1.0	-0.7
Whole body water mass	0.7	4.0	14.5	-2.7	-1.0	0.1	-2.7	-3.8	-1.9	2.7	-1.6	1.0	-0.1	3.3	-1.2	-1.5	-2.5	-2.1	-0.7	0.2	-0.9
Alcohol drinker status: Never	0.7	0.8	2.8	-0.9	-1.3	-0.9	-0.9	-0.6	-1.1	-1.4	0.2	-1.2	-0.8	0.2	-0.6	-1.7	-0.2	-0.9	-0.5	0.7	-0.8
Risk taking	0.7	1.0	3.5	0.4	-0.7	-1.0	1.0	1.5	0.1	-1.6	0.1	-1.4	-0.4	-1.9	-0.2	0.9	1.5	-0.0	0.9	-0.7	0.3
Fractured/broken bones in last 5 years	0.7	0.9	3.3	-0.9	-0.4	-0.2	-0.5	-1.2	-0.7	-0.1	-1.5	0.4	-0.9	0.9	-1.0	-1.8	-1.0	-0.9	-0.8	-1.2	-0.2
Ulcerative Colitis (UC)	0.6	1.1	5.0	-0.5	-0.4	1.2	-1.1	-1.6	-0.5	1.3	1.0	0.3	1.1	2.2	1.0	-1.2	0.1	-0.2	-0.7	1.4	-0.0
Major Depression (MDD)	0.6	0.8	7.3	0.6	0.6	0.9	0.6	0.3	0.6	2.7	-0.2	0.6	0.6	-0.2	0.4	1.2	0.3	0.7	-0.3	0.7	0.8
Verbal and Numeric Reasoning (VNR)	0.6	1.5	7.8	-0.7	-0.3	0.1	-1.1	-1.8	-0.2	-0.2	-0.9	0.6	-1.1	1.9	-0.7	-2.3	-2.8	-0.5	-1.5	-0.2	0.1
Blood Eosinophil Count	0.6	5.0	19.9	-0.2	1.8	4.1	-0.6	-2.6	0.6	3.0	1.1	3.8	2.2	4.5	1.8	-0.9	0.5	0.8	-0.8	2.2	1.5
Blood White Count	0.6	4.6	16.6	-1.1	0.6	3.2	-1.6	-3.2	-0.5	3.3	1.2	3.1	3.1	4.1	1.5	-1.2	1.5	-0.0	-0.4	1.9	-0.5
Nervous feelings	0.6	1.1	4.3	-1.1	-0.3	0.1	-1.5	-2.1	-0.8	0.0	-1.0	0.1	-0.3	1.9	-0.5	-1.5	-1.2	-0.8	-1.1	-0.3	-0.8
Had menopause	0.6	0.8	2.2	-1.1	-1.5	0.0	-1.4	-1.5	-1.1	-0.8	0.1	-0.2	0.2	1.4	-0.0	-0.8	0.5	-0.9	-0.4	0.9	-0.7
Fluid intelligence score	0.6	1.2	5.0	0.0	0.3	0.4	-0.3	-1.2	0.5	0.1	-1.9	0.6	-1.7	1.7	-1.0	-1.2	-2.2	0.3	-1.5	-0.2	0.9
Weight	0.6	2.7	27.8	0.5	1.8	1.5	0.5	-0.7	0.7	5.3	-1.2	1.6	0.1	1.1	0.3	1.2	-1.3	0.7	-0.4	0.6	2.4
Number of live births	0.6	0.8	2.3	-1.1	-0.9	-0.9	-0.5	0.5	-1.4	-0.5	0.9	-1.5	0.6	-1.1	-0.6	-0.6	0.4	-1.3	-0.6	0.6	-1.0
Medication: Lansoprazole	0.6	0.6	2.0	0.6	0.7	0.7	0.6	0.8	0.5	0.4	1.4	-0.2	0.9	-0.5	1.1	0.1	1.1	0.7	-0.9	1.3	0.7
Lung cancer (father)	0.6	0.7	2.4	0.5	-0.0	0.8	1.0	1.1	0.5	0.1	1.1	0.8	1.5	-0.6	1.0	0.7	0.9	0.4	0.8	1.3	0.0
Illnesses of mother	0.6	0.7	3.1	-0.7	-0.6	-1.1	-0.6	-0.2	-0.6	-1.8	-0.7	-0.5	-0.9	-0.1	-0.8	-0.8	-0.9	-0.8	0.6	-0.9	-0.9
Birth weight of first child	0.6	1.1	4.1	0.1	-0.6	1.2	-0.6	-1.2	0.4	1.3	2.0	1.8	0.8	1.7	1.2	0.2	0.9	0.6	1.1	-0.1	-0.2
Arm fat-free mass (right)	0.6	3.0	9.5	-2.1	-0.5	0.2	-2.1	-3.1	-1.4	2.9	-2.0	1.0	-0.3	2.7	-1.3	-0.7	-2.7	-1.6	-0.3	-0.0	-0.4
Alcohol intake frequency.	0.6	1.4	5.7	0.2	-0.2	0.5	0.1	0.6	-0.3	1.2	2.4	-0.4	2.2	-0.7	1.8	0.4	1.4	0.4	1.3	2.1	-0.3
Smoking status: Previous	0.6	0.9	2.9	0.9	1.2	0.7	1.6	1.5	0.8	0.6	0.0	0.1	0.8	-1.2	0.5	1.7	0.4	0.9	0.4	0.6	1.1
Leg fat-free mass (right)	0.6	3.2	15.1	-1.9	-0.1	0.9	-2.1	-3.4	-1.2	3.9	-1.2	1.5	0.4	3.3	-0.4	-0.9	-1.5	-1.3	-0.7	0.4	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.7	0.5	0.7	-0.3	1.0	1.0	0.3	-1.6	-0.7	-0.8	-0.9	-0.9	-0.7	0.0	-0.2	0.3	-1.3	0.2	0.9
Commuting to job workplace: Walk	0.6	0.6	3.9	-0.6	-0.1	-0.9	-0.4	-0.1	-1.0	-0.8	-0.6	-2.0	0.4	-0.6	-0.5	-0.3	1.0	-0.7	0.5	-0.1	-1.3
Smoking status: Current	0.6	0.9	6.3	0.4	0.0	-0.4	0.3	0.5	-0.2	2.2	0.0	-1.4	0.8	-1.1	0.8	0.4	2.5	0.1	-0.1	0.1	0.1
Leg predicted mass (right)	0.6	3.1	14.6	-1.9	-0.1	0.9	-2.1	-3.4	-1.2	3.8	-1.2	1.4	0.3	3.2	-0.4	-0.9	-1.5	-1.2	-0.8	0.3	-0.1
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.7	1.0	0.9	-0.1	1.3	1.5	0.8	0.3	0.0	-0.5	-0.7	-1.4	0.0	0.6	0.2	0.6	0.0	1.2	1.6
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.8	-0.3	-0.3	0.7	-0.5	-0.4	-0.2	-1.1	1.9	0.4	0.7	0.8	0.8	-0.8	1.3	-0.1	-1.1	1.7	-0.1
Medication: Paracetamol	0.6	1.0	5.2	0.3	0.1	-0.1	1.3	1.5	0.1	-0.4	1.2	-0.5	0.1	-1.8	0.3	1.0	0.9	-0.1	-0.1	2.3	1.3
Medication: Lisinopril	0.6	0.7	7.1	0.3	0.9	0.5	0.2	-0.0	0.0	0.2	-1.1	-0.5	-0.6	0.6	-0.2	-0.7	-0.8	0.2	-2.7	-0.9	0.8
Medication: Atorvastatin	0.6	0.7	2.2	-0.1	-0.4	-1.2	0.3	0.8	-0.2	0.4	-1.5	-0.3	-1.1	-1.5	-1.5	1.3	-0.8	-0.5	0.2	-0.5	0.4
Ever smoked	0.6	1.0	3.5	0.8	0.8	0.1	1.4	1.6	0.4	0.9	0.5	-0.4	1.1	-1.9	1.0	1.5	1.7	0.5	0.5	0.3	0.4
Arm fat-free mass (left)	0.6	3.2	10.6	-2.3	-0.6	0.4	-2.2	-3.3	-1.6	3.2	-1.7	1.2	-0.0	2.9	-1.1	-0.8	-2.3	-1.8	-0.7	0.4	-0.3
Arm predicted mass (left)	0.6	3.0	9.9	-2.2	-0.6	0.3	-2.2	-3.1	-1.6	3.0	-1.6	0.9	-0.1	2.8	-1.1	-0.9	-2.0	-1.8	-1.0	0.6	-0.4
Bipolar Disorder (2018)	0.5	0.7	1.9	-1.2	-0.9	-0.4	-1.4	-1.0	-1.4	-0.1	0.6	-0.5	0.3	0.6	-0.4	-0.9	-0.2	-1.0	-0.9	-1.1	-0.9
Bipolar Disorder or Schizophrenia	0.5	1.1	3.3	-1.4	-1.2	-0.3	-1.8	-1.8	-1.4	0.5	0.1	-0.1	0.3	1.4	-0.6	-1.2	-0.5	-1.1	-0.4	-1.0	-1.0
Alzheimer’s Disease (in mother)	0.5	0.6	1.7	-0.7	0.4	0.2	-0.5	-0.6	-0.5	-1.3	-1.2	0.7	-0.4	1.0	-1.0	0.1	-1.1	-0.4	0.4	-1.3	-1.0
Bipolar Disorder (2011)	0.5	0.5	1.8	-0.8	-0.6	-0.0	-1.0	-1.3	-0.4	-0.0	-0.3	0.0	-0.6	1.3	-0.7	-1.0	-1.2	-0.6	-0.2	-0.0	-0.4
Height	0.5	8.8	37.4	-1.5	-1.6	-2.9	-1.9	-2.0	-0.9	-4.4	-4.0	-1.3	-5.2	1.3	-4.3	-1.2	-6.1	-1.8	0.3	-3.2	-0.3
Hypothyroidism (self reported)	0.5	1.0	4.0	-1.0	-0.3	0.3	-1.1	-2.0	-0.3	1.3	-0.8	1.5	-0.8	2.0	-0.8	-0.7	-0.5	-0.7	-0.2	-1.2	-0.1
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	2.3	-0.5	-1.1	-0.6	-0.5	0.0	-0.8	-0.6	-0.7	-1.2	-0.3	-0.5	-1.0	0.6	-1.5	-0.7	0.1	-0.2	-0.2
Supplements: Zinc	0.5	0.5	2.6	0.1	0.1	0.8	-0.5	-1.0	0.4	-0.8	0.9	1.0	0.1	1.6	0.6	-0.7	-0.0	0.4	0.6	0.4	-0.2
Leg fat-free mass (left)	0.5	2.8	15.8	-1.7	-0.1	0.9	-1.8	-3.0	-1.2	4.0	-1.0	1.4	0.5	2.9	-0.3	-0.7	-1.8	-1.1	-0.4	0.5	0.1
Current tobacco smoking	0.5	0.8	4.2	0.6	0.1	-0.5	0.5	0.9	0.1	2.0	-0.0	-1.1	0.8	-1.4	0.7	0.7	2.0	0.3	0.5	-0.1	0.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.9	0.6	0.9	0.9	0.8	0.4	0.5	0.9	0.1	0.9	0.2	0.1	0.7	1.4	0.3	0.6	0.8	0.5	0.8
Sitting height	0.5	3.4	16.8	0.1	-0.2	-1.8	0.3	-0.1	0.4	-3.0	-2.3	-0.5	-3.6	-0.3	-2.1	-1.1	-4.1	-0.3	0.2	-2.5	0.8
Leg predicted mass (left)	0.5	2.8	15.1	-1.7	-0.2	0.8	-1.9	-3.1	-1.2	3.9	-1.0	1.4	0.4	2.9	-0.3	-0.8	-1.9	-1.2	-0.5	0.5	0.0
Financial difficulties in last 2 years	0.5	0.7	2.8	-0.6	-1.3	-1.1	-0.5	0.4	-1.1	-0.2	0.4	-1.5	0.8	-1.2	-0.1	0.1	-0.3	-0.7	0.2	-0.1	-1.7
Pain all over the body in last month	0.5	0.5	2.3	-0.4	0.3	0.4	-0.3	-0.3	-0.4	0.1	1.1	0.2	1.5	0.2	0.8	0.1	0.9	-0.2	1.5	0.7	-1.1
Medication: Ramipril	0.5	0.6	2.7	-0.0	0.6	0.0	0.3	0.3	0.1	0.6	-1.0	0.1	0.2	-0.5	-0.4	1.5	-1.5	-0.1	1.7	0.9	0.6
Illnesses of siblings	0.5	0.7	2.5	1.1	0.9	0.2	1.1	0.9	1.2	0.6	0.2	0.6	0.1	-0.5	0.8	0.6	1.6	1.0	0.7	-0.0	0.7
Hip circumference	0.5	2.0	21.1	-0.1	1.2	1.2	-0.0	-1.1	0.0	4.6	-1.0	1.2	0.3	1.4	0.3	0.3	-1.4	0.2	-0.8	1.1	1.6
Length of working week for main job	0.5	0.6	2.7	0.1	0.3	0.4	0.1	0.3	0.3	0.4	1.1	0.3	1.0	-0.1	1.1	0.2	1.6	0.2	1.4	1.2	-0.1
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.2	-0.9	0.4	0.6	-1.0	-1.4	-0.6	1.5	0.1	0.7	1.0	1.3	-0.0	0.2	0.2	-0.7	0.8	0.5	-0.8
Emphysema/chronic bronchitis	0.5	0.5	1.6	0.2	0.0	0.8	-0.1	-0.3	-0.2	1.3	0.6	-0.3	1.2	0.3	1.1	1.2	1.0	0.5	0.8	0.8	0.2
Mean time to correctly identify matches	0.5	0.9	2.4	-1.1	-0.7	-0.2	-1.5	-1.6	-1.4	1.3	-0.6	-1.1	0.1	1.1	-0.2	-1.4	0.9	-0.9	-0.6	0.1	-0.6
Arm predicted mass (right)	0.5	2.8	9.2	-2.1	-0.5	0.2	-2.0	-3.0	-1.4	2.9	-1.7	1.0	-0.2	2.7	-1.2	-0.9	-2.4	-1.7	-0.3	0.3	-0.4
Mineral and other dietary supplements	0.5	0.7	3.4	0.4	0.5	-0.4	0.8	0.7	0.1	1.8	-1.7	-0.3	-0.1	-1.1	-0.5	0.9	-0.7	-0.0	0.6	-0.6	0.6
Basal metabolic rate	0.5	2.8	12.2	-1.9	-0.3	0.4	-1.9	-3.0	-1.2	3.5	-1.6	1.1	-0.2	2.7	-0.9	-0.8	-2.3	-1.4	-0.7	0.2	0.0
Cholesterol lowering medication	0.5	0.8	2.5	-1.3	-0.6	-1.0	-0.7	-0.3	-1.4	-0.8	-0.6	-0.8	-0.3	-0.5	-1.4	-0.5	-0.6	-1.6	-0.9	0.6	-0.3
Irritable Bowel Disease (IBD)	0.4	0.9	2.8	-0.8	-1.1	-0.2	-1.4	-1.7	-0.7	0.3	-0.8	-0.7	-0.7	1.7	-0.4	-0.9	-0.9	-0.7	-1.2	0.4	-0.3
Body Mass Index (BMI) (2010)	0.4	0.5	5.8	0.1	0.5	0.3	-0.0	-0.3	-0.0	2.4	-0.9	0.4	0.2	0.2	0.0	0.1	-0.4	0.1	-0.7	-0.9	0.7
HbA1C	0.4	0.4	1.5	-0.2	1.2	0.6	0.3	0.1	0.5	-0.8	-1.1	0.8	-1.1	0.6	-0.8	0.1	0.2	0.2	0.0	-0.0	0.3
Lupus	0.4	0.7	5.7	-0.0	-0.1	-0.7	0.3	0.5	0.1	-0.2	-2.4	-0.8	-1.1	-0.5	-1.2	0.1	-1.2	-0.3	-0.2	-0.1	0.3
Schizophrenia (2014)	0.4	0.8	2.2	-1.2	-1.0	-0.4	-1.5	-1.3	-1.4	0.2	0.3	-0.3	0.2	0.9	-0.7	-1.1	-0.5	-1.0	-0.7	-0.4	-0.9
Cardiovascular Disease	0.4	1.4	3.8	1.0	0.8	-0.4	1.6	1.4	0.7	1.8	-1.9	-0.8	-0.7	-1.7	-0.4	1.9	-0.2	0.6	-0.2	0.1	1.6
Hand grip strength (left)	0.4	1.0	2.7	0.9	0.8	0.1	1.3	1.6	0.7	0.1	1.0	-0.4	1.0	-1.6	0.9	1.2	0.3	0.7	1.0	1.6	0.6
Hearing difficulty/problems: Yes	0.4	0.6	1.6	0.7	1.0	0.5	0.7	0.4	1.1	-1.3	0.8	1.1	-0.5	0.2	0.8	-0.6	0.9	0.7	-0.1	0.2	0.8
Relative age of first facial hair	0.4	0.8	3.3	-0.9	0.1	0.8	-0.5	-1.1	-0.6	-0.6	-0.1	0.7	0.4	1.6	-0.4	-1.3	-0.1	-0.7	-1.2	1.8	-0.4
Vitamin and mineral supplements	0.4	0.5	3.4	-0.0	0.6	-0.5	0.1	0.1	-0.3	0.9	-1.8	-1.0	-0.9	-0.3	-1.0	-0.1	-0.2	-0.2	-0.6	-0.8	0.4
Hearing difficulty/problems with background noise	0.4	0.7	1.7	1.3	0.6	0.3	1.1	1.0	1.3	-0.3	0.8	0.4	-0.6	-0.4	0.7	0.8	-0.3	1.2	0.4	-0.7	1.1
Alcohol intake versus 10 years previously	0.4	0.5	1.6	-0.9	-0.1	-0.9	-0.5	0.1	-0.9	-0.2	-0.0	-1.1	-0.1	-0.6	-0.6	-1.3	-0.5	-0.8	-1.3	0.2	-1.1
Asthma	0.4	0.9	5.2	-0.9	-0.2	0.1	-1.3	-1.2	-0.8	2.3	-0.1	0.1	1.0	0.5	-0.0	0.2	-0.3	-0.6	1.3	-0.3	-1.4
Pulse wave Arterial Stiffness index	0.4	0.5	2.0	0.8	-0.3	-0.5	0.4	0.1	0.8	-0.7	-1.0	0.1	-1.4	0.1	-0.3	0.2	-1.0	0.5	-0.1	-1.3	0.8
Standing height	0.4	4.3	20.3	-1.2	-0.9	-1.9	-1.2	-1.6	-0.6	-2.7	-2.9	-0.4	-3.3	1.1	-2.7	-1.2	-4.5	-1.3	0.5	-2.8	-0.3
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	3.1	-1.1	-0.4	0.6	-1.1	-1.7	-0.6	1.8	0.1	1.2	0.4	1.7	-0.1	-0.6	0.3	-0.8	0.0	0.2	-0.5
High blood pressure (siblings)	0.4	0.5	5.9	0.1	0.2	0.5	0.2	-0.4	0.1	-0.1	-0.7	0.4	-0.7	0.8	-0.0	-0.5	-2.4	0.2	-0.9	-0.0	0.6
Wheeze or whistling in the chest in last year	0.4	0.7	3.1	-0.5	-0.5	-0.2	-0.3	0.3	-0.7	1.8	0.2	-0.8	1.3	-1.0	0.1	1.2	0.5	-0.6	0.8	0.8	-0.9
Number of children fathered	0.4	0.5	2.6	-0.3	0.5	1.1	-0.2	-0.6	-0.2	0.9	-0.2	1.0	0.3	1.1	0.1	-0.6	0.1	-0.1	-0.7	1.6	0.3
Pulse wave peak to peak time	0.4	0.5	1.6	-1.1	0.1	0.4	-0.8	-0.5	-1.0	0.6	0.7	-0.1	1.2	0.2	-0.0	-0.4	0.7	-0.8	-0.0	1.0	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	3.4	-0.1	-0.5	0.1	-0.5	-0.4	-0.1	0.1	1.8	0.5	1.0	0.2	0.7	-0.4	-0.6	0.1	0.5	-0.7	-1.3
Family relationship satisfaction	0.4	0.5	1.9	0.1	-0.6	0.3	-0.4	-0.4	-0.0	1.1	1.2	0.3	1.4	0.1	1.1	0.9	0.5	0.3	1.1	0.1	-0.2
Leg pain on walking	0.4	0.5	1.1	0.5	0.7	0.9	0.4	-0.1	0.8	-0.4	0.6	1.1	-0.2	0.8	0.7	-0.4	0.7	0.6	0.9	0.6	0.8
Friendships satisfaction	0.4	0.5	2.1	0.6	0.5	0.5	0.8	0.1	1.1	-0.3	-0.1	1.4	-0.4	0.5	0.6	0.4	0.4	0.7	0.6	0.7	1.2
Asthma (self-reported)	0.4	0.8	5.3	-0.8	-0.2	-0.1	-1.1	-1.0	-0.8	2.3	-0.5	-0.1	0.9	0.3	-0.1	0.4	-0.2	-0.6	1.2	-0.6	-1.3
Diastolic blood pressure, automated reading	0.4	1.2	5.2	0.3	1.6	-0.1	1.0	0.5	0.5	0.5	-2.3	-0.4	-2.0	-0.2	-1.4	-0.1	-0.7	0.1	-1.1	0.1	1.8
Intelligence (Savage-Jansen 2018)	0.3	1.1	4.4	0.4	0.5	0.5	-0.1	-0.9	0.7	-1.2	-0.9	0.8	-1.6	1.6	-0.4	-1.1	-2.1	0.5	-1.1	-1.0	1.0
Schizophrenia (2018)	0.3	0.6	2.0	-0.9	-0.9	-0.1	-1.3	-1.4	-0.8	0.8	-0.4	0.1	0.1	1.2	-0.6	-0.9	-0.4	-0.7	0.2	-0.6	-0.7
LDL Cholesterol	0.3	0.4	2.5	-0.8	-0.4	-0.8	-0.4	-0.4	-0.7	-0.7	0.1	-0.2	-0.2	-0.2	-0.8	-0.8	-1.6	-0.5	-0.2	-0.3	-0.9
Blood Red Count	0.3	2.8	9.3	1.0	1.3	-0.8	1.6	1.4	0.9	0.6	-2.9	-0.6	-2.2	-1.5	-2.1	0.3	-3.0	0.6	-1.6	-1.8	2.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.0	0.3	0.5	1.4	0.3	-0.1	0.5	0.6	1.3	1.3	1.2	0.9	1.3	0.0	0.4	0.4	0.7	0.7	0.5
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.4	-0.7	-0.9	0.0	-0.9	-1.2	-0.7	0.3	-0.3	-0.1	0.2	1.1	-0.1	-0.8	-0.4	-0.5	-0.1	0.4	-0.7
Medication: Levothyroxine sodium	0.3	0.5	2.1	-0.8	-0.8	-0.1	-0.9	-1.0	-0.6	1.4	-0.3	0.3	-0.0	0.8	-0.4	-0.1	0.4	-0.6	-0.5	-0.8	-0.6
Alcohol usually taken with meals	0.3	0.5	5.9	-0.3	-0.3	-0.3	-0.4	-0.2	-0.1	-2.4	1.0	0.2	-0.8	0.7	-0.1	-0.3	-0.3	-0.2	-0.4	0.4	-0.8
Had other major operations	0.3	0.4	3.1	-0.3	-0.7	-0.4	0.1	0.6	-0.5	-0.5	0.3	-0.6	0.7	-0.9	0.0	0.0	0.4	-0.3	0.2	1.7	-0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.5	-0.3	-0.4	-0.7	-0.2	0.4	-0.7	0.2	0.4	-1.2	0.8	-1.2	0.4	0.6	0.2	-0.5	0.2	-0.2	-0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.9	-0.4	-0.6	-1.0	-0.5	0.2	-0.5	-1.1	-0.4	-1.4	-0.5	-0.6	-0.5	0.5	-0.2	-0.5	0.6	0.1	-0.8
Hair/balding pattern: Pattern 3	0.3	0.4	1.5	-0.5	-0.6	0.4	-0.7	-0.9	-0.6	0.0	-0.1	0.1	0.7	1.0	0.3	-1.2	0.9	-0.3	-0.2	-0.2	-0.9
Pulse rate	0.3	0.5	1.7	-0.7	-1.1	-0.4	-0.9	-1.0	-0.7	0.0	-0.2	0.0	-0.2	0.6	-0.6	0.0	-0.0	-0.6	0.6	-1.0	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	3.8	0.5	0.2	-0.1	0.2	0.4	0.6	0.2	0.4	0.5	0.5	-0.6	0.7	0.4	-0.2	0.5	2.0	0.1	-0.1
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.5	-0.1	-0.2	0.3	0.2	0.0	-0.3	1.0	0.3	-0.2	0.5	-0.1	0.6	-0.9	1.2	-0.2	-1.1	1.2	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.6	0.1	0.6	1.0	0.2	0.0	0.1	0.0	-0.6	0.3	0.5	0.7	-0.0	1.3	-0.5	0.3	-0.5	-1.2	0.0
Health satisfaction	0.3	0.4	1.0	0.7	0.1	0.2	0.7	0.8	0.5	0.2	0.5	-0.2	0.6	-0.8	1.0	0.7	0.7	0.7	0.9	0.7	0.2
Medication: Allopurinol	0.3	0.4	1.2	0.3	0.5	-0.6	0.6	0.6	0.4	-0.1	-0.9	-0.6	-1.1	-0.8	-0.8	0.4	-0.8	0.0	0.6	-0.3	0.7
Pulse rate, automated reading	0.3	1.1	3.2	-1.3	-1.0	-0.2	-1.6	-1.8	-1.2	0.6	0.2	-0.2	-0.1	1.3	-0.6	-1.2	0.8	-1.1	-0.3	-0.9	-1.4
Illnesses of siblings: Diabetes	0.3	0.4	2.9	-0.2	0.1	0.3	-0.2	0.5	-0.2	-0.1	1.1	-0.0	0.6	-0.4	0.1	0.9	1.7	-0.2	0.2	0.5	-0.6
Ever had bowel cancer screening	0.3	0.4	1.0	0.7	0.5	0.3	0.7	0.9	0.7	-1.0	0.8	0.3	-0.3	-0.5	0.7	-0.2	0.6	0.6	0.6	-0.0	0.6
Mother’s age at death	0.3	0.4	1.5	-0.5	-0.6	0.1	-0.7	-0.5	-0.5	-0.3	0.5	-0.2	-0.4	0.6	-0.1	-1.1	0.8	-0.5	-1.1	1.2	-0.1
Medication: Blood pressure	0.3	0.5	1.2	0.4	0.4	0.4	0.9	1.0	0.2	1.0	-0.5	-0.5	0.2	-1.0	-0.1	1.1	-0.4	0.3	-1.0	0.9	1.0
Worry (Nagel 2018)	0.2	0.5	1.1	0.9	1.0	0.8	0.8	0.4	1.0	0.8	-0.6	0.8	0.1	-0.1	0.4	0.7	-0.3	0.9	-0.0	-0.7	0.7
Age at First Birth	0.2	0.3	2.0	-0.2	0.0	0.1	-0.3	-0.5	0.1	-1.4	0.8	0.7	-0.2	0.8	-0.1	-0.6	-0.6	-0.2	-0.2	0.6	-0.2
Rheumatoid Arthritis	0.2	0.3	1.2	0.5	0.0	0.0	0.6	1.1	0.2	0.0	0.9	-0.4	0.3	-1.1	0.2	1.0	0.5	0.3	0.4	-0.0	0.5
Heel T-Score	0.2	1.6	5.8	0.5	1.2	1.7	0.8	1.1	0.5	1.1	2.0	1.8	2.4	0.2	1.9	0.1	1.4	0.7	-1.2	0.6	-0.2
Allergy or Eczema	0.2	0.6	1.9	-0.5	-0.2	-0.8	-0.9	-0.4	-0.4	-1.2	-1.1	-0.4	-1.4	0.2	-1.1	0.6	-1.2	-0.6	0.3	-0.7	-0.3
Hair Pigment	0.2	4.6	11.4	-2.6	-2.2	-1.0	-3.2	-3.4	-2.3	-0.7	-2.0	-1.0	-1.0	2.5	-2.3	-2.4	-0.4	-2.4	-1.9	-1.1	-2.8
Medication for hormone replacement therapy	0.2	0.2	0.4	0.5	0.1	0.4	0.3	-0.0	0.5	-0.1	-0.1	0.5	-0.1	0.3	0.5	0.6	0.2	0.6	0.5	-0.5	0.5
Severe depression (siblings)	0.2	0.3	0.8	-0.7	-0.6	-0.0	-0.2	-0.4	-0.8	0.4	0.2	0.5	0.8	0.1	-0.0	-0.9	-0.9	-0.6	-0.2	0.6	-0.5
Stomach or abdominal pain in last month	0.2	0.3	1.4	0.4	0.7	0.2	0.8	0.6	0.5	1.2	-0.9	0.6	-0.3	-0.5	-0.0	0.2	-0.1	0.4	0.0	-0.0	0.7
High blood pressure (mother)	0.2	0.3	1.3	-0.4	-0.6	-0.7	0.0	0.1	-0.3	0.5	-1.1	-0.6	-0.5	-0.6	-1.0	0.3	-0.4	-0.5	-0.5	-0.3	-0.4
Allergy	0.2	0.5	2.5	0.6	0.3	0.4	1.1	0.3	0.8	0.2	0.1	0.6	-0.2	0.1	0.4	-1.1	0.8	0.5	-1.1	0.9	1.6
Happiness	0.2	0.3	2.2	0.1	-0.2	-0.2	-0.0	-0.1	0.0	0.5	0.5	0.2	0.2	-0.2	0.3	1.1	0.4	0.1	1.5	0.5	-0.1
Comparative height size at age 10	0.2	1.4	5.7	0.4	0.6	0.2	0.2	-0.4	0.8	1.4	-1.9	0.7	-1.4	1.0	-0.8	1.6	-2.4	0.4	1.4	-1.4	1.1
Average weekly red wine intake	0.2	0.3	1.4	0.2	-0.1	-0.1	-0.3	0.1	-0.0	-0.6	1.2	-0.6	0.6	-0.4	0.8	0.3	0.3	0.2	0.8	-0.2	-0.7
Osteoarthritis (self-reported)	0.2	0.3	0.9	0.3	0.5	0.6	0.5	0.5	-0.0	0.8	0.3	-0.3	0.9	-0.3	0.6	0.4	0.9	0.3	-0.4	0.9	0.6
Average weekly champagne plus white wine intake	0.2	0.3	0.9	-0.6	-0.1	0.3	-0.8	-0.8	-0.4	0.1	0.5	0.3	0.4	0.9	0.5	-0.4	0.8	-0.4	-0.5	1.0	-0.3
Financial situation satisfaction	0.2	0.2	1.9	0.0	-0.2	-0.2	0.4	0.5	0.1	-0.7	0.5	0.1	-0.7	-0.3	-0.3	-0.6	-0.1	-0.1	-1.4	0.1	0.1
High cholesterol (Self-reported)	0.2	0.4	2.1	0.3	0.3	-0.0	0.7	1.0	0.1	0.7	0.0	0.0	0.6	-1.2	0.0	1.4	0.5	0.1	0.4	0.4	0.5
Ever depressed for a whole week	0.2	0.3	1.0	-0.5	-0.6	-0.3	-0.4	0.2	-0.6	0.2	0.7	-0.3	0.8	-0.6	0.5	0.1	0.4	-0.6	-1.0	0.4	-0.8
Commuting to job workplace: Cycle	0.2	0.2	1.3	-0.2	-0.0	0.5	-0.5	-0.9	-0.3	-0.1	0.2	0.1	0.1	1.2	0.7	-0.8	-0.0	-0.0	0.1	0.1	-0.0
Heart disease (siblings)	0.2	0.2	0.7	-0.6	-0.6	-0.1	-0.5	-0.4	-0.8	0.2	0.4	-0.3	0.6	-0.2	0.0	-0.3	0.3	-0.5	0.4	0.3	-0.2
Ovarian Cancer	0.1	0.2	1.2	-0.1	0.7	0.2	-0.2	-0.5	0.1	0.6	-1.1	0.3	-0.1	0.6	-0.3	0.5	0.0	0.0	0.1	-0.3	-0.3
Tanning	0.1	1.7	8.9	-0.5	-1.9	-1.7	-0.1	1.2	-0.7	-3.0	1.0	-0.6	0.0	-2.0	-0.5	-0.3	-0.5	-0.9	0.6	-1.8	-1.6
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.5	0.1	0.1	0.3	0.2	-0.1	0.3	-0.3	-0.0	0.3	-0.2	0.1	0.1	0.4	0.0	0.1	0.1	0.4	0.7
Hand grip strength (right)	0.1	0.4	1.2	0.5	0.0	-0.5	0.8	1.0	0.4	-0.0	-0.5	-0.6	-0.6	-1.1	-0.3	0.9	-0.4	0.2	0.4	0.8	0.3
Number of incorrect matches in round	0.1	0.2	0.7	-0.2	0.4	0.8	-0.1	-0.3	-0.7	0.7	0.4	-0.3	0.8	0.7	0.3	-0.3	0.4	-0.1	-0.6	0.2	0.2
Falls in the last year	0.1	0.1	1.3	0.0	0.1	0.0	0.1	0.1	-0.0	0.3	-0.1	0.3	0.5	-0.3	0.4	0.2	0.6	-0.1	1.2	-0.0	-0.1
Medication for cholesterol	0.1	0.2	1.5	0.3	0.1	-0.1	0.0	-0.2	0.5	-0.3	0.2	0.4	-0.3	0.5	0.3	-0.5	0.3	0.3	1.2	-0.7	-0.5
Average weekly beer plus cider intake	0.1	0.2	0.9	0.2	0.2	0.1	0.6	0.9	-0.0	0.5	0.5	-0.1	0.2	-0.9	-0.2	0.1	-0.4	0.1	-0.6	-0.4	0.4
Blood Platelet Count	0.0	0.3	0.7	0.5	0.7	0.7	0.7	0.4	0.7	-0.7	-0.8	0.8	-0.2	0.4	0.1	0.2	-0.3	0.6	0.4	-0.2	0.4

Hub : Genes

NNT-AS1

Models

Trait associations