Best TWAS P=3.35e-33 · Best GWAS P=1.94e-35 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | TMEM161B-AS1 | 0.19 | 0.09 | lasso | 6 | 0.09 | 4.2e-04 | 4.5 | 6.7 | 2.2e-11 | 0.36 | 0.27 | 0.17 | TRUE |
| 2 | GTEx | Pituitary | TMEM161B-AS1 | 0.22 | 0.23 | lasso | 4 | 0.24 | 8.6e-07 | 3.7 | 5.1 | 2.8e-07 | 0.22 | 0.44 | 0.03 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 12.0 | 12.0 | 3.4e-33 | 0.95 | 0.00 | 1.00 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -8.5 | -7.6 | 3.6e-14 | 0.13 | 1.00 | 0.00 | TRUE |
| 5 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | RASA1 | 0.04 | 0.01 | lasso | 3 | 0.01 | 4.0e-02 | 5.8 | -5.9 | 3.3e-09 | -0.06 | 0.02 | 0.77 | TRUE |