Best TWAS P=6.47e-09 · Best GWAS P=4.46e-07 conditioned to 7.2e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FUT10 | 0.12 | 0.20 | lasso | 11 | 0.21 | 4.2e-25 | -4.8 | -5.6 | 2.1e-08 | 0.06 | 0.02 | 0.97 | FALSE |
2 | GTEx | Artery Aorta | RP11-722E23.2 | 0.10 | 0.08 | enet | 24 | 0.05 | 6.0e-04 | -4.5 | -5.7 | 9.0e-09 | 0.05 | 0.04 | 0.93 | FALSE |
3 | GTEx | Artery Tibial | FUT10 | 0.15 | 0.19 | lasso | 6 | 0.20 | 2.1e-15 | -4.7 | -5.2 | 1.8e-07 | 0.05 | 0.04 | 0.94 | FALSE |
4 | GTEx | Lung | RP11-722E23.2 | 0.13 | 0.09 | lasso | 6 | 0.10 | 6.1e-08 | -5.0 | -5.2 | 1.8e-07 | 0.08 | 0.03 | 0.96 | FALSE |
5 | GTEx | Muscle Skeletal | FUT10 | 0.09 | 0.07 | enet | 17 | 0.07 | 1.7e-07 | -4.4 | -5.3 | 1.0e-07 | 0.09 | 0.03 | 0.95 | FALSE |
6 | GTEx | Nerve Tibial | FUT10 | 0.22 | 0.29 | enet | 18 | 0.32 | 1.3e-23 | -5.0 | -5.3 | 1.2e-07 | 0.06 | 0.02 | 0.98 | FALSE |
7 | GTEx | Pancreas | FUT10 | 0.28 | 0.23 | enet | 20 | 0.22 | 1.4e-09 | -4.5 | -5.8 | 6.5e-09 | 0.20 | 0.03 | 0.96 | TRUE |
8 | GTEx | Thyroid | FUT10 | 0.22 | 0.20 | enet | 22 | 0.26 | 8.6e-20 | -4.8 | -5.2 | 1.5e-07 | 0.06 | 0.03 | 0.95 | FALSE |
9 | GTEx | Uterus | FUT10 | 0.28 | 0.18 | enet | 21 | 0.18 | 1.7e-04 | -4.5 | -5.2 | 2.0e-07 | 0.09 | 0.05 | 0.81 | FALSE |
10 | GTEx | Whole Blood | FUT10 | 0.25 | 0.24 | lasso | 5 | 0.23 | 7.0e-21 | -5.0 | -5.2 | 1.8e-07 | 0.11 | 0.01 | 0.99 | FALSE |
11 | NTR | Blood | MAK16 | 0.02 | 0.01 | lasso | 3 | 0.01 | 5.1e-05 | -4.7 | -5.8 | 7.7e-09 | 0.32 | 0.03 | 0.64 | FALSE |
12 | ROSMAP | Brain Pre-frontal Cortex | FUT10 | 0.04 | 0.04 | enet | 11 | 0.04 | 2.1e-05 | -4.4 | -5.2 | 2.2e-07 | 0.05 | 0.03 | 0.95 | FALSE |
13 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | FUT10 | 0.10 | 0.11 | enet | 14 | 0.12 | 1.2e-10 | -5.0 | -5.3 | 1.3e-07 | 0.06 | 0.02 | 0.98 | FALSE |
14 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | FUT10 | 0.12 | 0.10 | blup | 68 | 0.09 | 2.6e-04 | -4.8 | -5.2 | 1.7e-07 | 0.04 | 0.02 | 0.94 | FALSE |