TWAS
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Cardiovascular Disease
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chr1:88,621,347-90,053,563
Best TWAS P=2.03e-09 · Best GWAS P=1.59e-08 conditioned to 0.347
88.6M
88.8M
89M
89.2M
89.4M
89.6M
89.8M
90M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
YFS
Blood
GTF2B
0.01
0.00
lasso
3
0.01
0.00023
5.7
6.0
2.0e-09
0.86
0.01
0.97
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
GTF2B
0.04
0.01
blup
53
0.01
0.02230
-4.2
5.5
4.6e-08
0.50
0.07
0.15
FALSE