TWAS hub - GTF2B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.0107	0.0060	0.0097	0.005	0.008	0.008	0.008	0.010	0.0082	0.00086	0.00081	0.00093	0.00023
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0422	0.0281	0.0055	0.014	0.010	0.001	NA	0.007	0.0093	0.02200	0.24000	NA	0.05300

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Vascular/heart problems diagnosed by doctor	13.1	35.8	48.9	-7.0	-4.8
Systolic Blood Pressure	12.8	64.0	82.1	9.1	6.8
High blood pressure	11.6	32.3	41.1	6.4	4.8
Hypertension (Self-reported)	10.6	29.6	37.3	6.1	4.7
Medication: Blood pressure	10.4	19.8	33.3	5.8	2.5
Cardiovascular Disease	10.0	33.0	36.0	6.0	5.5
Systolic blood pressure, automated reading	9.0	26.1	43.3	6.6	3.0
High blood pressure (mother)	7.3	10.3	12.1	2.9	3.5
Prospective memory result	6.8	8.4	11.8	3.4	2.2
Medication: Blood pressure	6.6	11.6	16.0	4.0	2.7
Birth weight of first child	6.4	11.7	20.6	-4.5	-1.6
Number of self-reported non-cancer illnesses	6.4	11.1	13.5	3.0	3.7
Medication for cholesterol, blood pressure or diabetes	5.7	9.4	11.4	-3.4	-2.7
Height	5.0	96.8	185.0	-13.6	-2.9
Medication: Atenolol	5.0	6.3	11.8	3.4	0.8
Medication: Bendroflumethiazide	4.8	7.2	10.1	3.2	2.1
Heel T-Score	4.7	37.4	66.1	8.1	2.9
Standing height	4.7	46.4	89.3	-9.4	-1.9
Medication: Ramipril	4.6	5.9	10.6	3.2	1.1
Number of children fathered	4.6	5.2	5.8	2.4	2.1
Illnesses of siblings	4.4	6.2	11.5	-3.4	-0.9
Illnesses of mother	4.2	5.2	5.6	-2.4	-2.2
Illnesses of siblings: Diabetes	4.2	5.1	7.4	2.7	1.7
Medication for cholesterol	4.2	6.4	12.3	-3.5	-0.6
Sitting height	4.0	28.5	53.0	-7.3	-2.0
Noisy workplace	3.9	4.8	8.3	2.9	-1.1
Leg fat percentage (right)	3.9	14.0	27.5	5.2	0.7
Commuting to job workplace: Car/motor vehicle	3.8	4.4	5.3	2.3	1.9
Blood Red Count	3.7	36.0	68.7	8.3	1.8
Qualifications: College or University degree	3.7	11.7	22.8	-4.8	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	3.6	7.4	14.5	-3.8	0.6
Diastolic blood pressure, automated reading	3.6	11.0	15.7	4.0	2.5
Supplements: Calcium	3.6	4.0	8.0	-2.8	0.2
Heart disease (siblings)	3.6	4.4	8.1	2.9	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	3.5	4.5	8.8	-0.4	-3.0
Heel bone mineral density (BMD) T-score, automated (left)	3.4	7.8	10.3	3.2	2.3
Stomach or abdominal pain in last month	3.4	4.2	5.1	-1.8	-2.3
Leg fat percentage (left)	3.3	11.9	23.5	4.8	0.4
Heel bone mineral density (BMD) T-score, automated (right)	3.2	7.3	10.8	3.3	1.9
Intelligence (Savage-Jansen 2018)	3.1	9.6	18.3	-4.3	-0.9
Alzheimer’s Disease (in father)	3.1	3.3	3.6	-1.9	-1.7
Worry (Nagel 2018)	3.0	6.3	10.6	3.3	1.4
Waist Hip Ratio (WHR)	2.9	13.0	17.1	-4.1	-3.0
Chronotype (morning person)	2.9	6.7	7.7	2.8	-2.4
Serious illness, injury or assault of a close relative in last 2 years	2.9	3.3	5.7	2.4	1.0
Tense / ‘highly strung’	2.9	4.8	6.3	2.5	1.8
Illnesses of father: High blood pressure	2.8	3.4	3.6	1.9	1.8
Ever had prostate specific antigen (PSA) test	2.7	3.1	5.8	-0.6	-2.4
Coronary Artery Disease (CAD)	2.6	3.1	4.8	2.2	1.2
Qualifications: CSEs or equivalent	2.6	3.4	6.5	2.6	0.5
Alcohol intake versus 10 years previously	2.6	3.8	5.6	2.4	1.4
Medication: Ventolin 100micrograms inhaler	2.6	3.3	6.6	0.2	2.6
Medication: Aspirin	2.6	3.5	5.0	2.2	1.4
Medication: Aspirin	2.6	3.4	4.7	2.2	1.5
Breast Cancer	2.5	6.1	12.2	3.5	-0.3
Angina	2.4	3.1	4.9	2.2	1.2
Hair/balding pattern: Pattern 2	2.4	3.0	6.0	-2.5	0.2
Qualifications: None of the above	2.4	5.2	10.0	3.2	0.6
Fluid intelligence score	2.4	4.9	9.4	-3.1	-0.6
Exposure to tobacco smoke at home	2.4	2.7	5.2	-2.3	-0.5
Ever had bowel cancer screening	2.4	2.8	4.9	-0.8	-2.2
Medication: Gliclazide	2.4	2.7	5.3	2.3	-0.3
Loneliness, isolation	2.3	3.1	4.7	-2.2	-1.3
Number of treatments/medications taken	2.2	3.9	6.3	2.5	1.2
Relative age voice broke	2.2	3.3	4.1	-2.0	-1.6
Medication: Cholesterol lowering	2.2	3.4	3.5	1.9	1.8
Breastfed as a baby	2.2	2.7	5.3	0.4	-2.3
Angina (self-reported)	2.2	2.9	4.8	2.2	1.0
Ever taken oral contraceptive pill	2.2	2.5	3.7	-1.9	-1.1
Frequency of depressed mood in last 2 weeks	2.1	2.9	5.8	0.0	-2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.8	3.1	-1.8	-1.6
Serious illness, injury or assault to yourself	2.1	2.5	4.4	-0.8	-2.1
Body mass index (BMI)	2.1	8.8	16.7	4.1	0.9
Birth weight	2.1	4.6	9.1	-3.0	-0.4
Comparative height size at age 10	2.1	11.6	21.8	-4.7	-1.1
High cholesterol (Self-reported)	2.1	3.6	4.9	2.2	1.6
Schizophrenia vs Biploar Disorder	2.0	2.6	2.8	1.7	1.6
Age at last live birth	2.0	2.8	5.7	-2.4	0.1
Commuting to job workplace: Walk	2.0	2.2	3.3	-1.0	-1.8
Alzheimer’s Disease (including proxy)	1.9	2.8	3.1	-1.8	-1.6
Sensitivity / hurt feelings	1.9	3.2	4.6	-2.1	-1.4
Hair/balding pattern: Pattern 4	1.9	4.6	9.2	3.0	0.2
Forced vital capacity (FVC), Best measure	1.9	7.0	13.8	-3.7	0.4
Mouth/teeth dental problems: Loose teeth	1.9	2.2	4.4	-2.1	-0.2
Mineral and other dietary supplements	1.9	2.5	5.1	2.2	0.1
Neuroticism (2016)	1.8	2.6	3.3	1.8	-1.4
Forced vital capacity (FVC)	1.8	6.9	13.6	-3.7	-0.4
Qualifications: A levels/AS levels or equivalent	1.8	4.0	4.8	-2.2	1.8
Pulse wave reflection index	1.8	2.2	4.3	2.1	-0.1
Age at first live birth	1.8	3.2	5.4	-2.3	0.9
Eye problems/disorders: Glaucoma	1.8	2.2	3.1	1.1	1.8
Hand grip strength (right)	1.7	4.5	8.9	-3.0	-0.2
Time employed in main current job	1.7	1.9	3.1	0.8	1.8
Impedance of arm (left)	1.7	8.1	13.3	-3.6	-1.7
High blood pressure (siblings)	1.7	2.5	4.2	2.1	0.9
Irritability	1.7	2.8	5.1	2.3	-0.7
Bipolar Disorder (2018)	1.6	2.5	5.0	-0.3	-2.2
Lung FEV1/FVC ratio	1.6	8.0	8.5	2.9	2.8
Medication: Lansoprazole	1.6	1.8	1.8	1.4	1.3
Miserableness	1.6	2.8	4.8	-0.8	-2.2
Ever depressed for a whole week	1.6	1.9	2.1	-1.3	-1.4
Commuting to job workplace: Cycle	1.6	1.9	3.1	-1.8	-0.9
Heart attack/myocardial infarction (self-reported)	1.6	2.1	4.2	2.0	-0.0
Hand grip strength (left)	1.5	4.1	8.0	-2.8	0.4
Townsend deprivation index at recruitment	1.5	2.1	2.8	-1.2	-1.7
Hearing difficulty/problems with background noise	1.5	2.3	3.0	-1.3	-1.7
Hayfever/allergic rhinitis (self-reported)	1.5	1.9	2.4	1.2	1.5
Breast cancer (self-reported)	1.5	1.7	2.6	-1.6	-1.0
Major Depression (MDD)	1.4	1.8	2.7	-1.6	-0.9
Allergy or Eczema	1.4	3.8	5.1	2.2	1.6
Ever had hysterectomy (womb removed)	1.4	1.6	2.9	-0.6	-1.7
Number of incorrect matches in round	1.4	2.2	4.2	2.0	-0.5
Arm fat percentage (right)	1.4	5.6	11.2	3.3	0.2
Chronic bronchitis/emphysema (mother)	1.4	1.6	1.9	1.2	1.4
Age at First Birth	1.3	1.9	3.7	-1.9	0.3
LDL Cholesterol	1.3	2.0	2.7	-1.6	-1.2
Blood White Count	1.3	9.4	17.4	4.2	1.2
Heart attack	1.3	1.7	3.3	1.8	-0.2
Headache pain in last month	1.3	2.2	3.7	-1.9	-0.8
Leg fat mass (right)	1.3	5.2	9.9	3.1	0.7
Hearing aid user	1.3	1.5	2.2	0.8	1.5
Medication: Paracetamol	1.3	2.0	3.7	1.9	0.5
Medication: Atorvastatin	1.3	1.7	2.7	1.6	0.8
Alcohol drinker status: Previous	1.3	1.5	2.7	-1.6	-0.5
Type 2 Diabetes (T2D) (2012)	1.2	1.3	2.1	1.5	0.7
BMI	1.2	7.1	14.1	3.8	0.3
Multivitamins +/- minerals	1.2	1.5	1.9	-1.1	1.4
Had other major operations	1.2	1.4	2.7	-0.4	-1.6
Impedance of arm (right)	1.2	5.7	8.6	-2.9	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	2.1	-1.4	-1.2
Arm fat percentage (left)	1.2	4.7	9.3	3.0	0.2
Osteoarthritis (self-reported)	1.2	1.6	3.1	0.2	-1.8
Bipolar Disorder (2011)	1.1	1.0	1.7	0.6	-1.3
Nervous feelings	1.1	2.1	4.1	2.0	0.2
Had menopause	1.1	1.4	1.8	-1.3	-1.0
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	2.2	-1.5	-0.7
Medication: Simvastatin	1.1	1.7	2.2	1.5	1.1
Worrier / anxious feelings	1.1	2.0	3.8	1.9	0.5
Number of live births	1.1	1.5	2.7	-0.6	-1.6
Glaucoma (self-reported)	1.1	1.3	2.6	0.1	1.6
Wheeze or whistling in the chest in last year	1.1	2.0	3.3	-1.8	-0.8
Shortness of breath walking on level ground	1.1	1.3	2.6	0.1	-1.6
Knee pain experienced in last month	1.1	1.7	2.9	1.7	-0.7
Medication: Lisinopril	1.1	1.4	2.1	1.5	0.8
Basal cell carcinoma (self-reported)	1.1	1.4	1.5	-1.2	-1.1
Leg fat mass (left)	1.1	4.5	8.6	2.9	0.6
Crohns Disease (2017)	1.0	2.3	2.3	1.5	-1.5
Verbal and Numeric Reasoning (VNR)	1.0	2.5	4.8	-2.2	0.3
Rheumatoid Arthritis	1.0	1.4	2.1	1.5	0.8
Blood Platelet Count	1.0	11.1	21.3	4.6	0.9
Pack years adult smoking proportion	1.0	1.5	2.5	-1.6	-0.7
Hayfever, allergic rhinitis or eczema	1.0	2.2	3.3	1.8	1.1
Gout (self-reported)	1.0	1.4	2.8	-0.1	-1.7
Body fat percentage	1.0	4.0	8.0	2.8	-0.0
Smoking status: Previous	1.0	1.5	2.9	0.3	-1.7
Tinnitus: Yes, now most or all of the time	1.0	1.1	1.3	1.1	-1.0
Unable to work because of sickness or disability	1.0	1.3	1.3	1.1	-1.1
Body Mass Index (BMI) (2010)	0.9	1.2	1.4	1.0	-1.2
Fasting Glucose	0.9	1.1	2.0	1.4	0.3
Age when periods started (menarche)	0.9	2.2	4.0	-0.6	2.0
Happiness	0.9	1.1	2.1	-1.5	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	3.8	-2.0	1.4
Medication for pain relief, constipation, heartburn	0.9	1.6	2.6	-1.6	-0.7
Neck or shoulder pain in last month	0.9	1.3	2.2	0.6	-1.5
Irritable Bowel Disease (IBD)	0.8	1.9	3.0	1.7	-0.8
Neuroticism	0.8	2.0	3.8	1.9	0.5
Medication for hormone replacement therapy	0.8	0.8	1.5	-0.4	-1.2
Vitamin and mineral supplements	0.8	1.1	2.0	1.4	-0.5
Medication: Metformin	0.8	1.1	2.2	1.5	-0.0
Bilateral oophorectomy (both ovaries removed)	0.8	1.0	1.1	-0.9	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	1.8	0.9	-1.4
Mouth/teeth dental problems	0.8	1.2	1.9	0.7	1.4
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	1.8	-1.3	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	1.9	-1.4	-0.9
Commuting to job workplace: Public transport	0.8	1.0	1.8	-0.5	-1.3
Alcohol drinker status: Never	0.8	0.9	1.1	1.1	0.8
Age started oral contraceptive pill	0.8	1.0	1.8	-1.3	-0.4
Type 2 Diabetes (T2D) (2018)	0.7	1.3	1.9	1.4	0.8
Relative age of first facial hair	0.7	1.4	1.8	-1.0	-1.3
Arm fat mass (right)	0.7	2.8	5.6	2.4	0.2
Medication: Paracetamol	0.7	1.1	2.0	1.4	0.4
Medication: Amlodipine	0.7	1.0	1.7	1.3	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.2	-1.1	-0.6
Health satisfaction	0.7	0.9	1.2	1.1	-0.7
Migraine (self-reported)	0.7	0.9	1.2	-1.1	-0.7
Mood swings	0.7	1.2	2.5	1.6	0.2
Guilty feelings	0.7	1.0	2.0	-0.0	-1.4
Pack years of smoking	0.7	1.0	1.3	-1.1	-0.9
Impedance of whole body	0.7	3.7	5.1	-2.3	-1.5
Ovarian Cancer	0.6	0.8	1.6	-0.0	1.3
Crohns Disease (2012)	0.6	0.9	1.7	0.4	-1.3
Respiratory disease	0.6	1.3	2.2	-1.5	0.6
Supplements: Zinc	0.6	0.6	1.2	-0.0	1.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	0.8	0.9	-0.8
Past tobacco smoking	0.6	1.0	2.1	-0.0	1.4
Neuroticism score	0.6	1.2	1.7	1.3	-0.8
Mouth/teeth dental problems: Dentures	0.6	1.0	1.1	0.9	-1.0
Ever highly irritable/argumentative for 2 days	0.6	0.7	0.9	0.9	-0.7
Number of full brothers	0.6	0.7	1.2	-0.5	-1.1
Emphysema/chronic bronchitis	0.6	0.6	1.0	-0.5	-1.0
Chest pain or discomfort	0.6	0.9	1.3	0.7	-1.2
Had major operations	0.6	0.7	1.0	-0.6	-1.0
Illnesses of father: Heart disease	0.6	0.9	1.7	1.3	0.3
Leg fat-free mass (right)	0.6	3.4	6.8	-2.6	-0.3
Average weekly red wine intake	0.6	0.8	1.3	-1.1	0.6
Eye problems/disorders: Cataract	0.6	0.7	1.0	-1.0	0.6
Leg predicted mass (right)	0.6	3.4	6.7	-2.6	-0.3
Arm fat mass (left)	0.6	2.3	4.6	2.1	0.2
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.5	-1.2	-0.1
Ever smoked	0.6	1.1	2.1	-0.3	-1.5
Risk taking	0.6	0.8	1.7	-1.3	0.1
Bipolar Disorder or Schizophrenia	0.5	1.1	2.1	-0.3	-1.5
Medication: Co-codamol	0.5	0.6	1.1	-0.2	1.1
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.6	-0.8	0.6
Pain all over the body in last month	0.5	0.6	1.1	0.2	1.1
Trunk fat-free mass	0.5	2.7	5.0	-2.2	0.6
Asthma	0.5	0.9	1.5	-1.2	0.6
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.0	-1.0	0.8
Suffer from ‘nerves’	0.5	0.8	1.4	0.4	-1.2
Whole body fat-free mass	0.5	2.8	5.5	-2.3	0.3
Long-standing illness, disability or infirmity	0.5	0.8	1.6	0.2	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	1.1	-0.1	-1.0
Wears glasses or contact lenses	0.5	0.5	0.9	-0.4	-0.9
Number of operations (self-reported)	0.5	0.7	1.0	-0.7	-1.0
Neuroticism (Nagel 2018)	0.4	0.9	1.6	1.3	-0.5
Ulcerative Colitis (UC)	0.4	0.7	1.3	1.1	-0.4
Leg fat-free mass (left)	0.4	2.0	3.9	-2.0	0.0
Trunk fat percentage	0.4	1.6	3.0	1.7	-0.4
Leg predicted mass (left)	0.4	2.0	4.0	-2.0	0.0
Alcohol usually taken with meals	0.4	0.7	1.1	1.1	0.6
Allergy	0.4	1.0	1.6	-1.3	-0.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	2.4	-1.6	0.8
Trunk predicted mass	0.4	2.5	4.6	-2.1	0.6
Worry too long after embarrassment	0.4	0.7	0.8	-0.9	-0.7
Medication: Seretide 50 evohaler	0.4	0.5	0.8	-0.9	0.5
Heart disease (mother)	0.4	0.5	0.9	0.9	0.3
Alcohol intake frequency.	0.4	0.9	1.6	-0.5	1.3
Qualifications: nursing, teaching	0.4	0.6	1.3	-1.1	0.1
Asthma (self-reported)	0.4	0.8	1.5	-1.2	0.4
Whole body water mass	0.4	2.5	4.9	-2.2	0.4
Mother’s age at death	0.4	0.5	0.7	0.9	0.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.6	-0.8	-0.7
Depressed Affect (Nagel 2018)	0.3	0.7	1.4	0.2	-1.2
Alzheimer’s Disease (in mother)	0.3	0.3	0.5	-0.4	-0.7
HDL Cholesterol	0.3	0.4	0.8	0.1	-0.9
Ulcerative Colitis	0.3	0.4	0.8	0.1	-0.9
Lung FVC	0.3	1.3	2.6	0.2	1.6
Diabetes (father)	0.3	0.4	0.6	0.8	0.4
Severe depression (siblings)	0.3	0.4	0.4	-0.7	-0.6
Diabetes (self-reported)	0.3	0.5	1.1	-0.1	-1.0
Pulse wave Arterial Stiffness index	0.3	0.3	0.3	-0.6	-0.6
Medication: Allopurinol	0.3	0.4	0.8	0.0	-0.9
Whole body fat mass	0.3	1.1	2.2	1.5	-0.2
Family relationship satisfaction	0.3	0.4	0.7	-0.8	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.3	0.6	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.1	-0.1	1.1
Basal metabolic rate	0.3	1.6	3.1	-1.8	0.3
Prostate Cancer	0.2	0.3	0.5	0.3	-0.7
Schizophrenia (2014)	0.2	0.5	0.7	0.8	0.5
Blood Eosinophil Count	0.2	1.7	2.7	1.6	-0.9
Smoking Status	0.2	0.6	1.1	-0.2	-1.1
Hair Pigment	0.2	5.5	10.8	3.3	-0.5
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.6	0.2	-0.7
Diabetes (mother)	0.2	0.2	0.2	0.4	-0.5
Fed-up feelings	0.2	0.4	0.8	-0.2	-0.9
Taking other prescription medications	0.2	0.3	0.3	0.5	0.6
Medication: Levothyroxine sodium	0.2	0.3	0.5	0.3	-0.7
Financial difficulties in last 2 years	0.2	0.2	0.2	-0.5	0.4
Father’s age at death	0.2	0.3	0.4	-0.3	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.7	0.2	-0.8
Falls in the last year	0.2	0.2	0.3	0.6	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.5	-0.2	0.7
Loud music exposure frequency	0.2	0.3	0.4	-0.4	-0.6
Arm fat-free mass (right)	0.2	1.0	1.4	-1.2	0.7
Exposure to tobacco smoke outside home	0.2	0.3	0.4	-0.6	-0.5
Comparative body size at age 10	0.2	0.5	0.9	0.2	1.0
Pulse wave peak to peak time	0.2	0.2	0.4	-0.2	0.6
Eye problems/disorders: None of the above	0.2	0.2	0.3	0.4	0.5
Arm predicted mass (right)	0.2	0.8	1.2	-1.1	0.6
Diabetes diagnosed by doctor	0.2	0.3	0.6	0.8	-0.2
Back pain experienced in last month	0.2	0.3	0.3	-0.5	0.5
Illnesses of father: None of the above (group 1)	0.2	0.3	0.6	-0.8	-0.0
Average weekly champagne plus white wine intake	0.2	0.2	0.4	-0.6	-0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.4	0.1	-0.7
Average weekly beer plus cider intake	0.2	0.2	0.4	-0.4	0.6
Fractured/broken bones in last 5 years	0.2	0.2	0.5	0.1	-0.7
Myopia	0.2	0.2	0.5	-0.7	-0.0
Cholesterol lowering medication	0.2	0.3	0.4	0.7	0.5
Pain experienced in last month	0.2	0.3	0.6	-0.3	0.8
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.4	-0.4	-0.6
Depression (Nagel 2018)	0.1	0.2	0.3	-0.3	-0.6
Reaction Time	0.1	0.1	0.1	0.4	0.4
HbA1C	0.1	0.1	0.2	0.5	-0.2
Tanning	0.1	1.2	1.9	0.7	1.4
Average weekly spirits intake	0.1	0.1	0.1	0.1	0.4
Hearing difficulty/problems: Yes	0.1	0.2	0.2	0.3	-0.5
Current tobacco smoking	0.1	0.2	0.3	-0.4	-0.5
Average weekly fortified wine intake	0.1	0.1	0.3	0.5	0.0
Maternal smoking around birth	0.1	0.1	0.2	-0.5	-0.1
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	-0.5	-0.1
Impedance of leg (left)	0.1	0.3	0.5	-0.1	-0.7
Trunk fat mass	0.1	0.4	0.8	0.9	-0.3
Hip circumference	0.1	0.6	1.2	1.1	-0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.1	0.4	0.2
Pulse rate	0.1	0.1	0.2	-0.1	0.4
Depression (self-reported)	0.1	0.2	0.3	-0.6	-0.1
Lung cancer (father)	0.1	0.1	0.1	-0.4	0.3
Length of working week for main job	0.1	0.1	0.2	-0.0	-0.4
Peak expiratory flow (PEF)	0.1	0.2	0.4	-0.6	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.3	0.5	0.1
Medication: Ibuprofen	0.1	0.2	0.2	0.4	0.4
Medication: Omeprazole	0.1	0.1	0.2	0.2	-0.5
Mean time to correctly identify matches	0.1	0.1	0.2	-0.1	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	-0.1	0.4
Number of full sisters	0.1	0.1	0.1	-0.4	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.3	0.0	-0.6
Supplements: Vitamin C	0.1	0.1	0.1	-0.2	-0.3
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	-0.4	-0.1
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.5	-0.1
Smoking status: Current	0.1	0.2	0.3	-0.5	-0.2
Arm fat-free mass (left)	0.1	0.3	0.4	-0.7	0.3
Schizophrenia (2018)	0.0	0.0	0.0	-0.2	-0.1
Mean Putamen Volume	0.0	0.0	0.0	-0.1	0.1
Lupus	0.0	0.0	0.0	-0.1	0.1
Primary Biliary Cirrhosis	0.0	0.1	0.1	-0.0	0.4
Triglycerides	0.0	0.0	0.1	0.2	-0.1
Hypothyroidism (self reported)	0.0	0.0	0.0	0.1	0.0
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	0.1	-0.1
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.1	-0.3	-0.1
Impedance of leg (right)	0.0	0.1	0.1	0.3	-0.3
Supplements: Glucosamine	0.0	0.0	0.0	0.1	0.1
Waist circumference	0.0	0.2	0.3	0.1	-0.5
Weight	0.0	0.1	0.1	-0.4	0.1
Mouth/teeth dental problems: Bleeding gums	0.0	0.1	0.1	-0.2	0.3
Blood clot in the leg (DVT)	0.0	0.0	0.1	-0.3	-0.1
Pulse rate, automated reading	0.0	0.1	0.1	0.2	0.2
Overall health rating	0.0	0.1	0.1	0.3	-0.3
Leg pain on walking	0.0	0.0	0.0	0.0	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.1	-0.0	0.2
Friendships satisfaction	0.0	0.1	0.1	0.3	0.1
Financial situation satisfaction	0.0	0.0	0.1	0.1	-0.3
Arm predicted mass (left)	0.0	0.2	0.2	-0.5	0.4

Hub : Genes

GTF2B

Models

Trait associations