[Hub]/) : Traits : Cardiovascular Disease : ← →

chr14:70,676,661-72,273,020

Best TWAS P=2.31e-10 · Best GWAS P=3.22e-09 conditioned to 0.0381

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PCNX	0.07	0.05	enet	13	0.06	2.1e-07	-5.5	6.3	2.3e-10	-0.70	0.04	0.96	TRUE
2	GTEx	Adipose Subcutaneous	PCNX	0.17	0.21	lasso	3	0.22	1.9e-17	-4.9	5.5	3.0e-08	-0.93	0.05	0.95	FALSE
3	GTEx	Adipose Visceral Omentum	PCNX	0.09	0.04	lasso	2	0.03	9.9e-03	-5.6	5.6	2.3e-08	-0.94	0.02	0.93	FALSE
4	GTEx	Brain Hippocampus	PCNX	0.26	0.26	enet	18	0.18	5.3e-05	-4.9	5.2	1.9e-07	-0.80	0.14	0.69	FALSE
5	GTEx	Breast Mammary Tissue (Male)	PCNX	0.11	0.11	lasso	3	0.07	1.3e-02	-5.9	6.0	2.4e-09	-0.99	0.03	0.66	FALSE
6	GTEx	Esophagus Mucosa	PCNX	0.20	0.18	enet	18	0.20	2.4e-13	-5.9	5.2	2.3e-07	-0.92	0.01	0.99	FALSE
7	GTEx	Nerve Tibial	PCNX	0.41	0.49	lasso	7	0.49	8.4e-39	-5.2	5.2	1.9e-07	-0.84	0.21	0.79	FALSE
8	GTEx	Ovary	PCNX	0.25	0.20	lasso	2	0.17	6.2e-05	-5.2	5.2	2.3e-07	-0.81	0.06	0.76	FALSE
9	GTEx	Pituitary	PCNX	0.39	0.35	lasso	3	0.34	2.6e-09	-5.8	6.0	2.5e-09	-0.83	0.03	0.97	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	PCNX	0.18	0.18	lasso	4	0.19	1.7e-10	-4.9	5.7	1.2e-08	-0.94	0.02	0.98	FALSE
11	GTEx	Skin Sun Exposed Lower leg	PCNX	0.23	0.29	enet	30	0.29	2.1e-24	-4.9	5.2	1.7e-07	-0.89	0.19	0.81	FALSE
12	GTEx	Thyroid	PCNX	0.27	0.29	enet	36	0.27	4.8e-21	-4.9	5.7	1.3e-08	-0.85	0.26	0.74	FALSE
13	GTEx	Uterus	PCNX	0.20	0.02	enet	7	0.07	1.4e-02	-5.2	5.2	2.1e-07	-0.82	0.06	0.50	FALSE
14	METSIM	Adipose	PCNX	0.13	0.11	blup	440	0.11	2.5e-16	-5.0	5.7	1.1e-08	-0.80	0.23	0.77	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	PCNX	0.05	0.04	blup	92	0.04	4.2e-09	-5.6	5.4	6.8e-08	-0.82	0.03	0.97	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	PCNX	0.03	0.02	blup	92	0.03	4.9e-04	-4.9	5.3	1.5e-07	-0.85	0.08	0.88	FALSE
17	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PCNX	0.04	0.04	lasso	4	0.03	2.4e-04	-5.8	5.7	1.0e-08	-0.80	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	PCNX	0.06	0.06	blup	91	0.07	7.1e-08	-5.0	5.6	2.3e-08	-0.89	0.03	0.97	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	PCNX	0.08	0.06	blup	91	0.08	8.8e-08	-5.5	5.8	5.4e-09	-0.94	0.01	0.99	FALSE