[Hub]/) : Traits : Cardiovascular Disease : ← →

chr14:103,289,637-104,866,687

Best TWAS P=4.64e-09 · Best GWAS P=5.12e-08 conditioned to 0.0408

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	KLC1	0.06	0.02	lasso	2	0.00	2.2e-01	-4.7	5.3	1.0e-07	0.49	0.10	0.32	FALSE
2	GTEx	Adrenal Gland	KLC1	0.15	0.03	lasso	3	0.06	4.6e-03	4.4	5.3	1.1e-07	0.59	0.09	0.42	FALSE
3	GTEx	Artery Aorta	TRMT61A	0.14	0.07	lasso	5	0.12	6.4e-07	-4.8	-5.3	1.0e-07	-0.29	0.04	0.95	FALSE
4	GTEx	Artery Tibial	XRCC3	0.06	0.08	lasso	3	0.03	1.4e-03	4.8	5.4	6.2e-08	0.60	0.27	0.69	FALSE
5	GTEx	Brain Cortex	XRCC3	0.12	0.02	lasso	4	0.01	1.7e-01	4.4	5.1	2.7e-07	0.72	0.06	0.68	FALSE
6	GTEx	Brain Frontal Cortex BA9	APOPT1	0.17	0.07	lasso	3	0.08	4.6e-03	5.4	-5.8	6.9e-09	-0.94	0.03	0.83	FALSE
7	GTEx	Breast Mammary Tissue	KLC1	0.12	0.02	enet	26	0.07	2.9e-04	4.4	5.4	8.5e-08	0.66	0.28	0.66	FALSE
8	GTEx	Lung	CKB	0.07	0.01	lasso	2	0.01	3.4e-02	-4.7	-5.2	2.0e-07	-0.54	0.16	0.53	FALSE
9	GTEx	Muscle Skeletal	KLC1	0.11	0.07	lasso	7	0.08	3.3e-08	-4.5	5.2	2.6e-07	0.57	0.43	0.55	FALSE
10	GTEx	Nerve Tibial	KLC1	0.07	0.00	enet	22	0.01	8.5e-02	4.5	5.3	1.4e-07	0.63	0.10	0.69	FALSE
11	GTEx	Spleen	KLC1	0.15	0.05	lasso	3	0.03	6.4e-02	5.4	5.8	7.3e-09	0.92	0.04	0.62	FALSE
12	The Cancer Genome Atlas	Glioblastoma Multiforme	MARK3	0.12	0.05	blup	64	0.07	3.3e-03	-4.7	-5.7	1.2e-08	-0.63	0.02	0.26	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	C14orf153	0.04	0.01	blup	38	0.03	6.2e-04	3.7	-5.6	2.6e-08	-0.71	0.05	0.34	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	C14orf153	0.06	0.02	blup	38	0.04	2.4e-05	-4.5	-5.9	4.6e-09	-0.67	0.08	0.60	TRUE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	C14orf153	0.09	0.08	blup	38	0.09	6.2e-10	-4.4	-5.6	1.8e-08	-0.62	0.12	0.84	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	CKB	0.07	0.09	blup	32	0.10	1.1e-10	5.4	-5.6	2.0e-08	-0.91	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Stomach Adenocarcinoma	C14orf153	0.20	0.05	lasso	2	0.04	8.8e-04	5.4	-5.7	1.4e-08	-0.97	0.00	0.97	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	KLC1	0.04	0.01	blup	82	0.03	5.4e-04	3.8	5.5	3.4e-08	0.65	0.04	0.68	FALSE