Best TWAS P=6.97e-10 · Best GWAS P=1.97e-07 conditioned to 1.52e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | RP11-1055B8.4 | 0.33 | 0.12 | lasso | 7 | 0.14 | 3.2e-11 | -5.1 | 5.8 | 9.1e-09 | 0.11 | 0 | 1.00 | FALSE |
2 | GTEx | Brain Cerebellum | RP11-1055B8.4 | 0.25 | 0.27 | lasso | 2 | 0.27 | 1.3e-08 | -5.1 | 5.5 | 4.8e-08 | 0.18 | 0 | 0.99 | FALSE |
3 | GTEx | Nerve Tibial | RP11-1055B8.4 | 0.13 | 0.14 | enet | 30 | 0.19 | 1.6e-13 | -5.1 | 6.2 | 7.0e-10 | 0.15 | 0 | 1.00 | TRUE |
4 | GTEx | Skin Sun Exposed Lower leg | RP11-1055B8.4 | 0.21 | 0.10 | lasso | 3 | 0.10 | 7.4e-09 | -5.1 | 5.7 | 1.1e-08 | 0.18 | 0 | 1.00 | FALSE |