[Hub]/) : Traits : Cardiovascular Disease : ← →

chr17:75,977,988-77,462,467

Best TWAS P=7.65e-10 · Best GWAS P=2.76e-10 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Brain Nucleus accumbens basal ganglia	USP36	0.36	0.23	lasso	5	0.20	4.8e-06	5.9	-6.2	7.7e-10	-0.97	0.04	0.94	TRUE
1	CommonMind	Brain Pre-frontal Cortex	USP36	0.14	0.13	lasso	3	0.13	1.7e-15	5.7	-6.0	1.8e-09	-0.96	0.04	0.96	FALSE
7	GTEx	Muscle Skeletal	CYTH1	0.13	0.12	lasso	3	0.13	2.5e-12	6.2	6.0	2.7e-09	0.91	0.03	0.97	FALSE
6	GTEx	Esophagus Mucosa	USP36	0.11	0.04	enet	13	0.06	1.1e-04	6.3	-5.9	3.4e-09	-0.87	0.02	0.97	FALSE
8	GTEx	Testis	USP36	0.32	0.24	lasso	6	0.26	6.2e-12	5.1	-5.8	5.2e-09	-0.92	0.04	0.96	FALSE
4	GTEx	Brain Cerebellum	USP36	0.31	0.20	enet	18	0.13	9.7e-05	5.9	-5.5	4.5e-08	-0.79	0.05	0.87	FALSE
3	GTEx	Brain Cerebellar Hemisphere	USP36	0.50	0.16	enet	20	0.07	5.7e-03	5.9	-5.3	1.2e-07	-0.81	0.05	0.89	FALSE
2	GTEx	Adipose Subcutaneous	CYTH1	0.13	0.03	lasso	5	0.04	5.7e-04	6.2	5.2	1.9e-07	0.83	0.04	0.83	FALSE
9	GTEx	Thyroid	CYTH1	0.24	0.07	lasso	11	0.06	3.4e-05	5.9	5.2	2.3e-07	0.84	0.04	0.96	FALSE