[Hub]/) : Traits : Cardiovascular Disease : ← →

chr17:75,977,988-77,462,467

Best TWAS P=7.65e-10 · Best GWAS P=2.76e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex USP36 0.14 0.13 lasso 3 0.13 1.7e-15 5.7 -6.0 1.8e-09 -0.96 0.04 0.96 FALSE
2 GTEx Adipose Subcutaneous CYTH1 0.13 0.03 lasso 5 0.04 5.7e-04 6.2 5.2 1.9e-07 0.83 0.04 0.83 FALSE
3 GTEx Brain Cerebellar Hemisphere USP36 0.50 0.16 enet 20 0.07 5.7e-03 5.9 -5.3 1.2e-07 -0.81 0.05 0.89 FALSE
4 GTEx Brain Cerebellum USP36 0.31 0.20 enet 18 0.13 9.7e-05 5.9 -5.5 4.5e-08 -0.79 0.05 0.87 FALSE
5 GTEx Brain Nucleus accumbens basal ganglia USP36 0.36 0.23 lasso 5 0.20 4.8e-06 5.9 -6.2 7.7e-10 -0.97 0.04 0.94 TRUE
6 GTEx Esophagus Mucosa USP36 0.11 0.04 enet 13 0.06 1.1e-04 6.3 -5.9 3.4e-09 -0.87 0.02 0.97 FALSE
7 GTEx Muscle Skeletal CYTH1 0.13 0.12 lasso 3 0.13 2.5e-12 6.2 6.0 2.7e-09 0.91 0.03 0.97 FALSE
8 GTEx Testis USP36 0.32 0.24 lasso 6 0.26 6.2e-12 5.1 -5.8 5.2e-09 -0.92 0.04 0.96 FALSE
9 GTEx Thyroid CYTH1 0.24 0.07 lasso 11 0.06 3.4e-05 5.9 5.2 2.3e-07 0.84 0.04 0.96 FALSE