Best TWAS P=5.98e-10 · Best GWAS P=3.23e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | CEP68 | 0.15 | 0.11 | lasso | 4 | 0.12 | 6.7e-10 | -5.9 | 6.2 | 6.0e-10 | -0.97 | 0.00 | 1.00 | TRUE |
2 | GTEx | Artery Aorta | CEP68 | 0.10 | 0.15 | lasso | 5 | 0.14 | 3.4e-08 | -5.4 | 5.4 | 5.5e-08 | -0.98 | 0.02 | 0.98 | FALSE |
3 | GTEx | Artery Coronary | CEP68 | 0.20 | 0.04 | lasso | 7 | 0.03 | 3.6e-02 | -5.4 | 5.4 | 8.6e-08 | -0.96 | 0.02 | 0.87 | FALSE |
4 | GTEx | Artery Tibial | CEP68 | 0.24 | 0.19 | lasso | 5 | 0.20 | 1.8e-15 | -5.9 | 5.8 | 8.0e-09 | -0.98 | 0.00 | 1.00 | FALSE |
5 | GTEx | Cells Transformed fibroblasts | CEP68 | 0.17 | 0.14 | lasso | 3 | 0.12 | 1.9e-09 | -5.4 | 5.4 | 6.1e-08 | -0.97 | 0.02 | 0.98 | FALSE |
6 | GTEx | Esophagus Gastroesophageal Junction | CEP68 | 0.25 | 0.01 | lasso | 4 | 0.08 | 8.6e-04 | -5.2 | 5.4 | 7.7e-08 | -0.78 | 0.01 | 0.91 | FALSE |
7 | GTEx | Esophagus Muscularis | CEP68 | 0.16 | 0.13 | enet | 7 | 0.17 | 2.2e-10 | -5.9 | 6.1 | 1.1e-09 | -0.94 | 0.00 | 1.00 | FALSE |
8 | GTEx | Heart Atrial Appendage | CEP68 | 0.26 | 0.20 | lasso | 3 | 0.19 | 4.6e-09 | -5.4 | 5.5 | 4.4e-08 | -0.98 | 0.01 | 0.99 | FALSE |
9 | GTEx | Heart Left Ventricle | CEP68 | 0.14 | 0.05 | lasso | 7 | 0.05 | 1.7e-03 | -5.9 | 5.9 | 3.4e-09 | -0.96 | 0.01 | 0.99 | FALSE |
10 | GTEx | Lung | CEP68 | 0.12 | 0.13 | lasso | 3 | 0.12 | 1.6e-09 | -5.9 | 5.6 | 1.7e-08 | -0.98 | 0.00 | 1.00 | FALSE |
11 | GTEx | Muscle Skeletal | CEP68 | 0.13 | 0.07 | lasso | 7 | 0.07 | 2.1e-07 | -5.9 | 5.8 | 6.5e-09 | -0.94 | 0.00 | 1.00 | FALSE |
12 | GTEx | Ovary | CEP68 | 0.38 | 0.26 | lasso | 7 | 0.24 | 1.6e-06 | -5.9 | 5.9 | 3.7e-09 | -0.97 | 0.00 | 0.99 | FALSE |
13 | GTEx | Testis | CEP68 | 0.26 | 0.27 | lasso | 5 | 0.26 | 5.3e-12 | -5.4 | 5.7 | 1.5e-08 | -0.99 | 0.00 | 1.00 | FALSE |
14 | YFS | Blood | CEP68 | 0.08 | 0.10 | lasso | 7 | 0.10 | 2.9e-30 | -5.4 | 5.8 | 6.8e-09 | -0.95 | 0.01 | 0.99 | FALSE |
15 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP68 | 0.04 | 0.03 | lasso | 4 | 0.02 | 4.0e-03 | -5.9 | 5.9 | 4.0e-09 | -1.00 | 0.00 | 0.98 | FALSE |