[Hub]/) : Traits : Cardiovascular Disease :

chr2:85,731,858-87,126,250

Best TWAS P=1.69e-10 · Best GWAS P=3.3e-07 conditioned to 0.026

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Nucleus accumbens basal ganglia REEP1 0.17 0.03 enet 14 0.07 5.0e-03 -4.4 5.2 1.6e-07 -0.81 0.05 0.68 FALSE
2 GTEx Breast Mammary Tissue MRPL35 0.10 0.05 lasso 8 0.08 8.9e-05 -4.0 5.2 2.3e-07 -0.92 0.04 0.90 FALSE
3 GTEx Ovary MRPL35 0.17 0.04 enet 15 0.07 1.0e-02 2.8 5.5 4.1e-08 -0.54 0.09 0.18 FALSE
4 GTEx Thyroid MRPL35 0.14 0.01 enet 31 0.07 7.9e-06 2.2 6.4 1.7e-10 -0.50 0.08 0.73 TRUE
5 The Cancer Genome Atlas Breast Invasive Carcinoma MRPL35 0.04 0.02 enet 7 0.02 1.6e-04 -4.9 5.5 4.2e-08 -0.93 0.00 0.99 FALSE