Hub : Genes

REEP1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1000 0.0390 7.1e-04 0.001 0.016 -0.002 0.019 0.001 2.3e-01 3.7e-03 8.0e-01 1.9e-03 2.3e-01
2 GTEx Adrenal Gland 0.2118 0.0867 1.7e-04 0.052 NA 0.062 NA 0.064 6.1e-03 NA 3.0e-03 NA 2.6e-03
3 GTEx Artery Tibial 0.0765 0.0313 4.2e-04 0.056 NA 0.044 NA 0.060 3.6e-05 NA 2.1e-04 NA 1.8e-05
4 GTEx Brain Caudate basal ganglia 0.1400 0.0620 4.6e-03 0.112 NA 0.025 NA 0.044 4.1e-04 NA 6.5e-02 NA 2.1e-02
5 GTEx Brain Cerebellar Hemisphere 0.2180 0.0780 2.2e-04 0.175 NA 0.141 NA 0.138 3.0e-05 NA 1.8e-04 NA 2.1e-04
6 GTEx Brain Cerebellum 0.2950 0.0810 5.1e-07 0.140 NA 0.152 NA 0.130 6.3e-05 NA 3.0e-05 NA 1.1e-04
7 GTEx Brain Cortex 0.1520 0.0710 7.5e-03 0.044 NA 0.050 NA 0.056 2.3e-02 NA 1.6e-02 NA 1.2e-02
8 GTEx Brain Frontal Cortex BA9 0.2188 0.0809 1.2e-03 0.158 NA 0.105 NA -0.011 5.6e-05 NA 1.0e-03 NA 9.7e-01
9 GTEx Brain Hippocampus 0.3276 0.1037 1.3e-04 0.225 NA 0.126 NA 0.213 5.2e-06 NA 7.4e-04 NA 9.6e-06
10 GTEx Brain Nucleus accumbens basal ganglia 0.1740 0.0730 2.0e-03 0.031 NA 0.074 NA 0.054 5.2e-02 NA 5.0e-03 NA 1.4e-02
11 GTEx Brain Putamen basal ganglia 0.2020 0.0730 4.3e-04 0.178 NA 0.040 NA 0.179 5.1e-05 NA 4.1e-02 NA 5.0e-05
12 GTEx Esophagus Muscularis 0.0640 0.0320 7.2e-03 0.022 NA 0.010 NA 0.031 1.6e-02 NA 7.1e-02 NA 5.1e-03
13 GTEx Lung 0.1531 0.0511 1.1e-06 0.059 NA 0.137 NA 0.079 2.5e-05 NA 1.2e-10 NA 1.2e-06
14 GTEx Pancreas 0.1590 0.0570 7.2e-04 0.115 NA 0.102 NA 0.139 1.5e-05 NA 4.6e-05 NA 1.9e-06
15 GTEx Skin Sun Exposed Lower leg 0.0860 0.0460 8.0e-03 -0.002 NA 0.018 NA 0.007 5.4e-01 NA 1.2e-02 NA 8.1e-02
16 GTEx Testis 0.1530 0.0640 6.0e-04 0.039 NA 0.020 NA -0.005 7.7e-03 NA 4.2e-02 NA 5.9e-01
17 METSIM Adipose 0.0411 0.0159 2.3e-04 0.016 0.020 0.023 0.021 0.020 1.4e-03 4.0e-04 1.8e-04 3.2e-04 4.0e-04
18 NTR Blood 0.0173 0.0065 8.5e-05 0.018 0.012 0.016 0.012 0.018 1.4e-06 6.9e-05 4.4e-06 5.9e-05 1.2e-06
19 ROSMAP Brain Pre-frontal Cortex 0.1110 0.0326 8.9e-15 0.116 0.116 0.136 0.128 0.136 1.1e-14 1.0e-14 4.4e-17 4.4e-16 3.7e-17
20 TCGA Breast Invasive Carcinoma 0.0395 0.0223 2.8e-06 0.031 0.020 0.013 NA 0.020 4.2e-07 4.7e-05 7.6e-04 NA 4.4e-05
21 TCGA Head and Neck Squamous Cell Carcinoma 0.0404 0.0221 1.2e-03 0.001 0.022 0.017 NA 0.005 2.2e-01 1.4e-03 4.6e-03 NA 8.1e-02
22 TCGA Kidney Renal Clear Cell Carcinoma 0.0416 0.0203 1.9e-06 0.070 0.048 0.052 NA 0.063 2.6e-08 3.7e-06 1.7e-06 NA 1.3e-07
23 TCGA Lung Adenocarcinoma 0.0290 0.0152 1.7e-03 0.023 0.025 0.034 NA 0.029 9.3e-04 5.3e-04 7.4e-05 NA 2.2e-04
24 TCGA Lung Squamous Cell Carcinoma 0.1419 0.0591 3.4e-07 0.035 0.063 0.087 NA 0.059 6.3e-05 1.1e-07 4.0e-10 NA 2.7e-07
25 TCGA Prostate Adenocarcinoma 0.1649 0.0515 0.0e+00 0.173 0.189 0.186 NA 0.189 9.0e-18 2.1e-19 4.8e-19 NA 2.1e-19
26 TCGA Soft Tissue Sarcoma 0.0490 0.0300 1.9e-03 0.072 0.036 0.037 NA 0.048 4.5e-05 3.3e-03 2.9e-03 NA 8.1e-04
27 TCGA Testicular Germ Cell Tumors 0.1020 0.0480 1.4e-04 0.042 0.068 0.014 NA 0.053 1.3e-02 2.0e-03 1.0e-01 NA 5.8e-03
28 TCGA Thyroid Carcinoma 0.1690 0.0540 4.1e-14 0.098 0.164 0.175 NA 0.176 9.1e-10 9.6e-16 9.9e-17 NA 6.5e-17

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28
Bipolar Disorder (2018) 0.6 0.9 6.5 2.5 0.9 0.9 0.5 1.0 1.1 -0.7 0.2 0.5 -0.2 0.6 1.1 0.2 -2.2 0.9 -0.2 0.2 -0.5 0.1 0.6 0.1 0.2 -0.5 -0.8 1.6 1.2 0.2 -0.6
Bipolar Disorder or Schizophrenia 0.5 1.1 5.5 2.4 0.1 0.0 0.6 1.4 0.9 -0.6 0.5 0.6 0.0 0.4 0.9 2.1 -2.1 1.7 -0.6 1.4 0.4 0.6 0.7 -0.3 0.4 0.8 0.3 1.7 1.0 0.2 0.2
Depressed Affect (Nagel 2018) 1.6 3.4 9.2 0.4 2.9 -0.6 2.1 1.8 1.7 2.4 1.8 1.5 2.2 2.1 -2.5 -2.1 -1.6 0.2 3.0 2.1 0.6 2.4 1.5 1.9 1.5 1.6 1.4 0.8 1.0 2.1 1.7
Depression (Nagel 2018) 0.5 0.8 4.3 0.3 0.8 -1.8 0.5 0.8 0.6 0.3 0.6 0.5 1.2 0.3 -0.5 -0.4 -1.1 -0.1 1.4 2.1 1.2 0.9 1.0 0.9 0.8 0.8 0.5 0.1 -0.4 0.4 1.3
Intelligence (Savage-Jansen 2018) 2.9 8.9 15.9 0.1 1.7 -0.0 3.1 3.2 2.3 3.8 3.6 3.7 3.6 3.0 -3.6 -1.6 -0.0 4.0 3.1 2.9 0.5 3.0 3.3 3.1 3.6 3.6 3.3 2.8 3.2 3.4 3.5
Neuroticism (Nagel 2018) 3.2 7.6 17.4 1.5 3.8 -0.3 2.9 2.8 2.8 3.2 3.0 2.7 2.8 2.9 -3.3 -1.9 -4.0 1.0 4.2 3.0 0.7 3.5 2.8 2.2 2.8 2.7 2.8 1.7 2.2 2.7 2.5
Schizophrenia (2018) 0.4 0.8 6.3 0.9 -0.6 -0.7 0.3 1.0 0.3 -0.1 0.4 0.4 0.2 0.0 0.2 2.5 -0.9 1.6 -0.6 1.6 0.9 0.6 0.5 -0.4 0.3 1.4 1.0 0.8 0.4 0.1 0.7
Schizophrenia vs Biploar Disorder 0.2 0.2 1.0 -0.3 0.7 -0.1 0.5 0.5 -0.4 0.6 0.4 0.2 -0.1 0.0 -0.6 -0.2 0.4 0.1 -0.7 0.8 0.4 0.5 0.0 -0.4 0.1 0.3 1.0 -0.0 -0.0 0.4 0.7
Worry (Nagel 2018) 4.2 8.8 20.7 1.9 3.5 0.5 2.9 3.2 3.2 3.2 3.3 3.2 2.7 3.0 -3.2 -1.4 -4.6 1.6 4.3 3.4 0.3 3.7 3.2 2.1 3.3 3.1 3.3 2.3 3.0 2.8 2.5
Alzheimer’s Disease (in mother) 2.2 2.6 5.8 0.8 2.0 -0.2 2.1 1.9 2.3 2.0 1.9 1.4 2.0 2.1 -1.9 -1.1 -0.8 2.2 1.2 0.6 0.7 2.4 1.5 1.6 1.3 1.4 0.8 1.4 1.3 2.1 1.5
Alzheimer’s Disease (in father) 1.2 1.3 2.6 0.5 1.2 -0.4 1.5 1.5 1.2 0.7 1.4 1.5 0.4 1.3 -0.6 -0.2 -1.5 0.6 0.8 1.6 0.6 1.1 1.4 0.6 1.5 1.3 1.5 1.4 1.0 0.9 1.1
Alzheimer’s Disease (including proxy) 3.0 4.3 7.6 0.4 2.4 -0.5 2.6 2.4 2.5 2.2 2.5 2.2 2.3 2.5 -2.1 -1.0 -1.0 2.7 2.1 1.9 1.1 2.8 2.1 2.0 2.1 2.2 1.5 2.0 1.7 2.5 2.1
Crohns Disease (2017) 0.3 0.8 2.8 1.7 -1.6 -0.5 0.6 1.1 0.3 -0.9 0.5 0.8 -0.5 0.3 1.3 1.4 0.1 1.3 0.4 1.0 1.0 -0.1 0.7 0.1 0.9 0.9 1.1 1.0 0.2 -0.4 0.5
Irritable Bowel Disease (IBD) 0.9 2.2 7.9 -0.3 -2.5 -1.0 -1.4 -1.1 -1.3 -2.6 -1.3 -1.0 -1.9 -1.6 2.8 2.5 1.5 0.3 -1.1 -0.0 1.1 -2.1 -1.0 -1.0 -0.9 -0.8 0.1 -0.8 -1.4 -2.0 -0.8
Ulcerative Colitis (UC) 1.9 3.5 8.0 -1.5 -2.0 -1.6 -2.3 -2.2 -1.9 -2.8 -2.0 -1.9 -1.9 -2.4 2.8 2.2 1.7 -0.5 -1.6 -0.5 0.9 -2.6 -1.7 -1.4 -1.7 -1.5 -0.0 -1.8 -2.0 -2.6 -1.1
Major Depression (MDD) 0.5 0.7 6.9 1.4 -0.3 0.1 0.3 0.5 1.1 0.2 0.2 0.3 0.7 0.4 -0.1 -0.4 -2.6 1.8 0.7 0.2 -0.5 1.1 0.6 -0.1 0.4 0.1 0.3 0.8 0.6 0.3 -0.1
Reaction Time 4.7 9.1 17.3 -0.6 -0.9 1.2 -3.3 -3.2 -3.4 -3.4 -3.4 -3.6 -4.2 -3.5 3.2 1.5 1.1 -3.2 -3.4 -2.5 -0.4 -3.9 -3.9 -3.3 -3.5 -3.2 -2.0 -3.3 -3.2 -3.7 -3.0
Verbal and Numeric Reasoning (VNR) 3.3 8.0 14.1 0.4 2.1 0.1 3.4 3.8 2.5 3.2 3.5 3.3 3.4 3.3 -3.1 -2.1 -0.6 2.4 3.0 3.0 1.0 3.3 3.2 2.9 3.2 3.0 2.4 3.1 2.7 3.2 3.2
Breast Cancer 0.5 1.3 4.8 1.9 0.1 -0.1 1.2 1.0 1.4 0.8 1.2 1.4 1.2 1.1 -0.6 -0.7 -2.2 1.5 0.7 0.7 0.4 1.6 1.5 0.6 1.4 1.0 0.6 1.4 1.0 1.0 1.1
Ovarian Cancer 0.2 0.2 2.4 0.1 0.7 -0.5 -0.2 0.4 0.4 0.3 0.2 -0.3 0.4 -0.1 -0.5 -0.6 0.4 -1.5 -0.2 0.1 0.4 0.6 -0.1 0.0 -0.1 0.3 -0.7 -0.3 -0.4 0.6 -0.1
Prostate Cancer 0.8 1.2 2.9 0.8 -1.7 -0.2 -1.1 -1.2 -1.2 -1.5 -1.4 -1.0 -0.9 -1.5 1.6 1.1 -0.7 -0.8 -1.6 -1.0 -0.4 -1.4 -0.7 -1.1 -1.0 -0.5 -0.4 -0.4 -0.6 -1.4 -0.8
Age at First Birth 0.5 0.7 2.5 -1.2 -0.2 -0.3 0.3 0.5 0.5 1.4 0.7 0.4 0.9 0.3 -1.6 0.8 -0.6 1.2 0.9 1.4 0.1 0.9 0.2 0.3 0.5 1.1 1.5 -0.3 0.5 0.6 0.5
Bipolar Disorder (2011) 3.3 3.2 7.0 1.2 1.2 1.2 2.3 1.9 2.1 1.8 1.9 2.1 2.1 2.4 -1.4 -1.3 0.1 1.9 2.6 0.0 -1.0 1.6 2.0 2.6 1.8 1.0 -0.0 2.4 2.6 2.2 0.9
Body Mass Index (BMI) (2010) 0.4 0.6 1.6 0.7 0.1 -0.2 0.7 0.9 1.1 0.7 0.4 0.6 1.1 0.7 -0.6 -0.6 -0.3 1.3 0.9 0.5 -0.7 0.7 0.7 1.1 0.5 0.7 -0.6 1.0 0.5 1.1 0.2
Coronary Artery Disease (CAD) 4.7 5.6 14.4 2.0 -0.9 -0.6 2.8 3.2 2.7 1.0 2.9 3.2 2.5 2.8 -0.6 0.7 1.6 2.9 1.5 1.8 1.1 2.2 3.3 2.9 3.1 2.8 0.9 3.8 2.4 2.5 2.2
Crohns Disease (2012) 0.3 0.4 1.8 0.6 0.2 0.6 1.0 1.4 0.2 -0.0 0.8 0.9 -0.4 1.0 0.4 1.1 0.2 1.0 0.4 0.7 0.1 0.3 0.5 0.1 0.7 0.2 0.4 1.1 0.5 0.6 0.2
Mean Putamen Volume 0.4 0.4 2.8 0.1 0.1 -0.5 0.6 -0.1 0.1 0.9 0.2 0.2 1.7 0.7 -1.0 -0.1 0.4 1.0 1.0 0.4 -0.3 0.6 0.4 1.4 -0.0 0.5 0.1 0.4 0.7 0.7 0.4
Fasting Glucose 0.6 0.7 3.3 -0.6 -1.4 -1.8 -0.6 -1.2 -0.9 -0.3 -0.6 -0.6 0.3 -0.7 0.0 0.1 1.7 -0.6 -0.7 -0.8 0.8 -0.9 -0.4 0.6 -0.4 -0.3 -0.1 -0.9 -1.4 -0.6 0.3
HbA1C 0.6 0.6 1.9 0.3 -1.3 0.3 -1.2 -0.7 -0.7 -1.0 -0.9 -0.6 -0.9 -0.8 1.0 1.4 -0.7 -0.4 -0.7 -0.3 -0.6 -1.2 -0.6 -0.7 -0.6 -0.0 -0.5 -0.3 0.1 -0.9 -1.1
HDL Cholesterol 1.6 2.7 7.8 -0.3 0.4 -0.7 -2.3 -1.6 -2.8 -1.4 -1.9 -2.0 -1.6 -2.2 1.1 1.0 0.8 -0.9 -2.0 -0.2 0.5 -1.7 -2.3 -2.3 -1.8 -1.3 -0.4 -2.4 -2.3 -1.9 -0.8
LDL Cholesterol 0.3 0.5 2.2 1.4 0.7 0.7 0.3 -0.1 0.6 0.0 -0.5 -0.4 -0.0 0.5 0.1 -0.1 -0.7 -0.5 -0.5 -1.1 -1.5 0.1 -0.4 -0.0 -0.6 -0.7 -1.2 0.3 0.5 0.1 -1.3
Lupus 0.7 1.1 2.1 -0.0 -0.6 0.3 -1.1 -1.1 -0.7 -0.9 -1.4 -1.3 -1.0 -1.1 0.9 1.0 -1.1 0.2 -1.1 -1.4 -1.1 -1.1 -1.3 -1.1 -1.3 -1.4 -0.9 -0.9 -0.7 -1.2 -1.4
Neuroticism (2016) 0.9 1.3 6.4 0.2 0.2 -0.8 0.9 0.9 0.8 0.6 1.1 1.2 1.0 0.7 -0.5 -0.5 -2.5 0.7 1.1 1.4 1.1 1.3 1.3 0.4 1.5 1.5 2.3 0.7 0.4 0.5 1.5
Primary Biliary Cirrhosis 0.2 0.3 1.1 -0.8 -0.9 0.2 -0.2 0.1 -0.1 -0.8 -0.2 -0.0 -0.9 -0.4 1.0 0.9 0.8 0.5 -0.5 -0.4 0.0 -0.9 -0.0 -0.0 -0.1 -0.5 -0.3 0.2 -0.1 -0.4 -0.2
Rheumatoid Arthritis 0.3 0.5 1.9 -0.5 -0.7 -1.3 -0.4 -0.5 -0.6 -0.9 -0.5 -0.4 -0.3 -0.7 0.8 1.4 -0.5 0.6 -0.2 0.3 1.0 -0.6 -0.4 -0.2 -0.2 0.4 0.7 -0.6 -1.0 -1.1 0.4
Schizophrenia (2014) 0.6 1.4 5.0 1.0 0.4 -1.0 1.2 1.8 1.1 0.5 1.2 1.1 1.0 0.7 -0.4 1.4 -0.6 1.5 -0.2 2.2 1.2 1.3 1.3 0.4 1.0 1.9 1.3 1.6 1.1 0.8 1.4
Triglycerides 0.1 0.1 1.0 1.0 -0.4 -0.6 0.5 0.1 0.4 0.1 -0.3 -0.2 -0.2 0.1 -0.0 -0.2 -0.3 -0.8 0.1 -0.1 -0.5 0.1 0.0 -0.1 -0.3 -0.5 -0.1 0.1 0.0 -0.2 -0.4
Type 2 Diabetes (T2D) (2012) 3.2 3.7 9.6 0.2 1.2 -1.0 1.9 2.0 2.2 3.1 2.2 1.8 2.6 2.1 -3.1 -1.8 0.5 1.6 2.0 -0.1 -0.2 2.6 1.8 2.3 1.7 1.8 1.5 1.1 2.1 2.8 1.6
Ulcerative Colitis 0.6 0.8 2.8 -1.7 -1.1 -1.5 -0.8 -0.9 -0.5 -1.3 -0.6 -0.6 -0.7 -1.1 1.4 0.9 1.0 0.7 -0.7 0.3 1.0 -1.1 -0.4 -0.4 -0.5 -0.3 0.6 -0.6 -0.9 -1.2 0.1
Blood Eosinophil Count 1.2 8.9 19.1 -1.1 -3.7 -0.7 -3.7 -2.2 -3.1 -4.0 -3.2 -2.7 -4.2 -4.3 4.0 3.7 1.9 -1.0 -3.3 0.5 1.0 -4.4 -2.9 -3.9 -2.5 -2.5 -0.7 -2.5 -2.9 -4.0 -1.7
Blood Platelet Count 1.8 20.8 49.7 3.0 2.9 2.4 5.3 4.8 6.3 4.8 5.1 5.3 4.0 5.7 -4.2 -2.5 -2.7 7.0 5.9 3.1 -1.6 5.3 5.0 4.4 4.9 3.1 2.0 5.5 6.3 5.4 2.4
Blood Red Count 0.2 2.1 9.2 0.9 -0.6 0.7 1.9 1.7 3.0 0.3 1.4 1.6 0.7 2.2 0.2 2.0 0.1 1.3 2.0 0.8 -0.1 0.8 1.5 2.0 1.3 0.9 -0.3 2.4 1.7 1.3 0.3
Blood White Count 0.2 1.2 12.1 0.6 -1.8 -1.8 0.3 0.6 0.3 -0.2 0.4 0.7 0.8 0.2 0.3 0.8 3.5 0.5 1.2 1.0 0.9 -0.7 0.8 2.0 0.8 0.9 0.5 0.5 -0.1 0.2 1.2
Heel T-Score 0.2 1.5 4.6 0.8 -0.2 -0.1 1.0 1.6 1.0 0.8 1.2 1.5 1.4 1.1 -0.6 -0.6 -1.8 0.0 1.6 2.1 -0.0 1.3 1.6 0.9 1.5 0.8 1.3 1.7 1.7 1.1 1.1
BMI 0.3 1.8 7.1 0.6 -2.7 -2.3 -1.6 -0.8 -0.8 -1.3 -1.1 -0.8 1.2 -1.4 1.1 2.4 2.6 0.5 -1.4 -0.0 1.3 -1.3 -0.2 0.8 -0.6 0.6 -1.6 -0.2 -1.5 -0.6 0.3
Height 0.1 1.5 10.0 -3.2 -0.7 -0.6 -0.6 -1.8 -1.7 0.9 -0.4 -0.5 -0.2 -1.3 -1.3 -1.9 1.6 -0.8 0.4 -0.9 0.2 -1.3 -0.7 -0.1 -0.2 0.1 2.2 -2.1 -1.0 -0.9 0.6
Waist Hip Ratio (WHR) 0.3 1.2 3.1 0.2 1.5 1.1 1.0 1.3 1.6 1.4 1.2 1.1 0.2 1.1 -1.3 -0.9 -1.8 0.2 1.3 0.7 -0.5 1.5 0.7 0.2 1.1 0.7 1.5 0.5 1.6 1.1 0.4
Systolic Blood Pressure 3.9 19.7 49.1 0.2 7.0 -2.1 5.3 4.2 4.6 4.9 5.8 4.2 4.6 5.3 -5.2 -6.0 -3.6 0.8 4.4 3.6 3.6 6.8 4.3 3.2 4.5 3.8 3.6 2.6 2.2 4.9 5.0
Smoking Status 2.7 6.5 10.9 -2.7 -1.3 1.4 -2.8 -3.2 -3.0 -1.7 -3.0 -3.0 -3.1 -2.3 1.5 1.4 2.2 -1.4 -1.8 -3.2 -2.1 -3.1 -3.2 -2.2 -2.9 -3.2 -1.7 -3.3 -2.6 -2.5 -2.9
Allergy or Eczema 0.4 1.1 7.3 1.9 -1.0 -1.1 0.3 1.1 0.9 -0.7 0.4 0.6 0.0 0.0 0.8 2.1 -0.5 2.7 -0.2 1.6 1.4 0.2 0.6 -0.3 0.7 0.8 0.9 1.0 -0.1 -0.4 0.8
Cardiovascular Disease 4.2 13.8 27.5 -0.0 4.0 -2.9 3.9 3.3 3.5 4.1 4.6 3.8 5.2 3.7 -4.4 -4.7 -0.2 0.2 4.0 2.5 3.2 4.7 4.3 4.4 4.2 4.4 3.0 2.4 1.8 4.2 4.6
Hypothyroidism (self reported) 0.5 1.2 4.0 -1.8 -0.9 0.1 -1.0 -1.4 -2.0 -0.4 -1.4 -1.6 -0.4 -1.2 0.2 0.2 1.0 -1.0 -0.1 -0.8 -0.3 -1.2 -1.7 -0.7 -1.6 -0.7 -0.7 -1.7 -1.4 -1.0 -0.7
Respiratory disease 0.9 1.9 7.8 0.1 -1.1 -2.8 -1.6 -0.9 -1.1 -1.7 -1.0 -1.2 -0.2 -1.9 1.4 2.0 1.1 -0.5 -1.0 1.3 2.2 -1.1 -0.9 -0.7 -0.8 0.5 0.8 -1.6 -2.2 -1.9 0.4
Type 2 Diabetes (T2D) (2018) 0.2 0.4 1.7 -1.3 -0.1 -0.2 -0.5 -0.6 -0.2 0.2 -0.4 -0.7 0.3 -0.1 -0.3 0.0 1.0 0.1 0.2 -1.2 -0.6 -0.1 -0.6 0.5 -0.6 -1.2 -0.9 -0.7 -0.3 0.3 -0.5
Lung FEV1/FVC ratio 2.0 9.9 24.8 -1.8 2.6 2.0 3.7 3.5 2.8 5.0 3.4 3.1 3.0 4.0 -4.7 -1.3 0.0 3.9 4.4 1.2 -2.7 3.3 2.7 3.8 2.6 1.4 1.9 2.4 4.3 4.6 1.2
Lung FVC 0.2 1.1 5.4 2.1 -1.9 -0.7 -0.6 -0.3 -0.6 -1.4 -0.8 0.2 -0.5 -0.8 1.8 2.3 -1.8 -0.3 -0.1 0.4 -0.8 -1.1 0.2 -0.3 0.1 0.2 1.0 0.7 0.5 -1.2 -0.3
Neuroticism 2.9 7.0 18.9 1.0 4.3 0.0 2.8 2.4 3.0 3.5 2.7 2.3 2.6 3.0 -3.7 -2.5 -4.1 1.5 3.8 2.0 0.1 3.5 2.3 2.0 2.3 2.0 2.7 1.0 2.2 2.6 2.0
Chronotype (morning person) 0.8 1.7 3.2 1.5 0.4 -0.0 1.0 1.7 1.1 1.3 1.4 1.5 1.6 1.1 -1.2 -0.8 -1.3 1.6 1.3 1.0 0.1 1.5 1.4 1.1 1.5 1.8 1.8 1.4 1.7 1.3 1.2
Hair Pigment 0.1 3.4 8.9 1.8 1.4 1.6 2.2 1.9 2.4 2.1 2.0 2.2 1.5 2.6 -1.7 -1.1 -1.7 1.4 1.7 -0.4 -1.3 2.1 2.0 1.7 2.0 1.0 0.5 2.3 3.0 2.3 0.6
Tanning 0.1 1.4 3.3 -0.8 -1.8 1.0 -1.1 -1.3 -0.5 -1.6 -1.1 -0.9 -1.4 -0.8 1.8 0.8 1.8 0.0 -0.5 -1.5 -0.9 -1.8 -1.0 -0.2 -0.9 -1.5 -1.7 -0.5 -0.4 -1.0 -1.4
Hand grip strength (left) 0.3 0.9 5.3 0.2 -2.3 -1.9 -0.7 -0.8 -0.2 -0.6 -0.2 0.4 1.0 -0.8 0.6 2.2 1.6 0.9 -0.6 -0.7 0.0 -0.8 0.5 1.1 0.6 1.0 0.3 0.4 0.0 -0.2 0.5
Number of treatments/medications taken 0.4 0.6 3.6 -0.2 1.9 0.2 1.0 0.2 0.3 1.0 0.5 -0.1 0.8 1.1 -1.0 -1.5 0.5 -0.4 0.5 -0.9 -0.3 0.8 0.2 0.8 -0.2 -0.7 -1.5 -0.1 -0.2 1.1 -0.2
Average weekly spirits intake 0.7 0.8 3.9 -1.4 -1.1 1.2 -0.9 -0.8 -0.0 -0.0 -1.0 -0.7 -0.7 -0.5 0.0 0.7 0.3 0.7 0.3 -1.3 -2.0 -0.9 -0.8 -0.2 -0.7 -1.3 -0.8 -0.9 -0.3 -0.3 -1.5
Sensitivity / hurt feelings 0.2 0.4 4.2 -0.7 0.9 -0.7 -0.4 -0.2 -0.0 -0.2 -0.2 -0.2 -0.4 -0.3 -0.0 0.4 -2.0 -0.6 0.2 0.7 0.3 0.1 -0.2 -0.7 -0.0 0.5 1.1 -0.8 -0.2 -0.6 0.0
Frequency of depressed mood in last 2 weeks 1.3 1.8 5.8 -0.2 1.7 -1.8 1.1 1.0 0.9 1.6 1.4 1.0 2.1 1.2 -1.8 -0.8 -0.6 -0.1 2.4 1.3 0.6 1.8 1.4 2.1 1.3 1.2 1.1 0.1 0.5 1.5 1.4
Hearing difficulty/problems: Yes 0.2 0.3 1.4 0.8 1.1 0.5 -0.2 0.6 0.6 0.4 0.4 0.4 -0.0 0.3 -0.5 -0.6 1.2 -0.5 0.5 0.0 -0.2 0.2 0.3 0.3 0.5 0.1 -0.1 0.0 0.8 0.6 0.0
Relative age of first facial hair 0.2 0.3 1.5 -1.2 0.3 0.4 -0.1 0.0 -1.0 -0.3 0.0 -0.1 -0.6 -0.2 0.4 0.2 -0.6 1.2 -0.2 1.2 0.2 -0.2 -0.2 -0.6 -0.2 0.2 1.1 -0.0 0.1 -0.4 0.1
Other serious medical condition/disability diagnosed by doctor 1.1 1.4 3.6 0.2 -1.0 -0.4 -1.5 -1.5 -0.6 -1.9 -1.3 -1.3 -1.0 -1.3 1.6 1.0 1.3 -0.5 -1.1 -0.6 1.0 -1.4 -1.1 -0.8 -1.1 -0.4 -1.5 -1.1 -1.9 -1.4 -0.5
Ever used hormone-replacement therapy (HRT) 0.2 0.3 3.8 0.0 0.9 0.2 0.2 0.2 -0.2 -0.1 0.1 -0.1 -0.4 0.3 0.0 0.5 -1.9 0.6 0.3 0.7 0.7 0.5 -0.1 -0.9 -0.1 -0.1 0.7 -0.2 -0.3 -0.5 0.3
Ever had hysterectomy (womb removed) 0.6 0.7 3.0 -1.1 -0.2 1.7 -0.5 -0.8 0.6 0.1 -0.2 -0.2 -0.8 0.0 -0.1 -0.3 -0.7 1.4 0.2 -1.5 -1.7 -0.0 -0.4 -0.4 -0.4 -1.0 -0.7 -0.1 0.6 0.4 -1.4
Systolic blood pressure, automated reading 2.7 8.0 19.9 -0.1 4.5 -0.5 3.3 2.7 3.5 3.0 3.6 2.7 2.7 3.6 -3.2 -4.2 -2.2 -0.1 3.0 2.8 2.0 4.4 2.7 1.7 2.7 2.4 1.1 2.1 1.8 3.4 2.8
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 2.1 -0.3 0.1 0.9 0.4 -0.3 0.4 0.4 -0.2 -0.3 0.1 0.5 -0.2 0.2 0.4 0.9 0.4 -0.7 -0.9 0.2 -0.3 0.4 -0.5 -0.6 -1.4 0.2 0.1 0.5 -0.7
Angina 0.5 0.7 3.3 0.1 1.8 -0.0 1.1 1.0 0.7 0.7 1.0 0.6 1.0 0.9 -0.5 -1.4 0.0 -0.9 0.9 0.4 0.5 0.7 0.9 1.2 0.5 0.3 0.1 0.7 0.6 1.0 0.7
Medication for hormone replacement therapy 0.5 0.6 2.0 0.2 -0.3 1.2 -0.6 -1.4 -0.9 -0.4 -0.9 -0.9 -0.4 -0.0 0.4 1.2 -0.3 -0.4 0.1 -1.2 -0.7 -0.5 -0.9 -0.2 -1.0 -0.8 -0.5 -0.7 -0.2 -0.8 -0.9
Vitamin and mineral supplements 1.9 2.6 5.8 2.0 0.5 -1.3 1.6 1.9 2.0 0.1 1.8 2.1 1.4 1.0 0.1 -1.1 -0.1 0.3 1.8 2.4 2.0 1.1 2.3 1.7 2.3 1.8 1.3 2.2 0.8 0.7 2.2
Supplements: Zinc 0.7 0.8 3.5 0.1 0.4 -1.4 0.5 0.4 0.3 1.1 0.6 0.4 1.4 0.1 -1.4 -1.3 0.2 0.6 0.1 0.5 1.1 1.0 0.5 0.4 0.6 1.9 1.4 -0.1 -0.2 0.7 1.2
Medication: Co-codamol 0.4 0.5 2.8 0.3 0.7 -1.7 -0.1 0.1 0.6 -0.3 0.1 0.0 0.5 -0.3 0.1 0.5 -1.5 -0.4 -0.2 1.3 1.4 0.6 0.5 -0.5 0.3 0.6 0.3 -0.2 -0.8 -0.1 0.8
Medication: Metformin 0.1 0.2 0.5 0.5 0.6 -0.4 0.4 0.1 -0.1 0.3 -0.3 -0.4 0.6 0.3 -0.2 -0.4 0.3 -0.6 0.7 -0.3 -0.6 -0.1 -0.3 0.7 -0.6 -0.6 -0.6 -0.1 -0.3 0.3 -0.3
Diabetes (father) 0.4 0.5 2.7 -0.5 1.6 -1.3 0.3 0.4 0.4 0.5 0.6 0.3 0.7 0.3 -0.7 -0.8 -0.2 0.4 0.7 1.2 1.0 0.9 0.5 0.5 0.5 0.6 0.4 -0.1 0.0 0.5 0.7
Diabetes (mother) 3.3 4.2 11.3 -1.0 -1.9 -1.9 -2.5 -2.5 -2.6 -2.0 -2.2 -2.4 -0.9 -2.4 1.5 1.4 3.2 -2.7 -1.9 -1.3 1.1 -2.2 -2.0 -0.9 -1.9 -0.9 -1.0 -2.9 -3.4 -2.2 -0.7
Severe depression (siblings) 0.4 0.5 2.2 0.3 -1.3 -1.3 0.2 0.2 -0.3 -0.2 0.1 0.6 0.7 0.0 0.2 0.2 0.2 -0.1 1.2 0.1 0.5 -0.5 0.8 1.5 0.7 0.8 1.2 0.1 -0.0 -0.3 0.9
Pack years adult smoking proportion 1.0 1.6 5.0 0.3 0.5 0.6 -1.4 -1.2 -0.4 -1.2 -1.4 -1.5 -1.6 -1.0 1.1 -0.3 -1.0 -0.6 -1.1 -1.5 -1.1 -1.0 -1.5 -1.6 -1.6 -2.2 -1.5 -1.2 -0.8 -0.9 -1.8
Impedance of leg (right) 0.4 1.7 5.2 -0.1 1.7 2.3 1.4 1.6 0.8 2.2 1.5 1.3 -0.4 1.7 -2.1 -1.1 -1.1 0.1 1.6 0.5 -1.6 1.7 0.6 -0.2 1.1 -0.1 1.2 0.5 1.9 1.4 -0.1
Leg fat-free mass (left) 0.3 1.4 4.5 -0.6 -1.9 -1.8 -1.5 -1.5 -0.7 -1.6 -1.2 -1.0 0.1 -1.6 1.2 0.3 2.1 -0.1 -1.2 -0.9 1.3 -1.6 -0.6 0.2 -0.7 0.4 -0.4 -0.8 -1.7 -1.1 0.2
Trunk fat percentage 0.1 0.6 1.5 1.2 -0.2 -0.4 0.3 1.0 1.2 0.1 0.7 0.7 1.0 0.7 -0.1 0.4 0.6 1.2 0.7 0.4 0.5 0.4 0.9 1.2 0.8 0.7 -0.2 0.9 0.5 0.9 0.7
Hand grip strength (right) 0.1 0.4 1.5 0.6 -0.5 -1.1 -0.1 -0.4 0.7 0.5 0.1 0.3 1.2 -0.2 -0.6 1.0 0.1 1.1 -0.1 -0.6 -0.7 0.1 0.3 0.9 0.4 0.6 0.5 0.2 0.5 0.5 0.2
Townsend deprivation index at recruitment 0.3 0.5 4.6 0.0 -0.0 -0.0 0.1 0.0 -0.4 0.5 0.2 0.3 0.4 0.3 -0.5 0.5 2.1 2.0 0.7 -0.6 -0.6 -0.4 0.1 1.2 0.3 -0.2 0.8 0.0 0.2 0.2 0.3
Current tobacco smoking 2.5 4.1 14.3 -1.8 -0.6 3.3 -1.3 -2.0 -1.4 -0.8 -2.0 -1.9 -2.8 -0.8 0.8 0.5 1.5 -0.7 -0.8 -3.8 -3.2 -2.2 -2.4 -1.3 -2.3 -3.3 -2.2 -1.6 -0.7 -1.1 -3.1
Average weekly fortified wine intake 1.4 1.7 6.8 0.2 0.9 1.2 1.6 1.6 1.6 0.6 1.4 1.5 0.0 1.5 -0.3 0.7 -1.5 2.6 0.7 1.5 0.0 1.4 1.2 0.4 1.2 1.1 1.3 2.1 1.9 1.2 0.6
Maternal smoking around birth 0.5 0.8 2.7 -1.6 -0.4 -1.1 -1.2 -1.4 -1.1 -0.2 -0.8 -0.8 0.0 -1.1 -0.3 0.2 1.2 -1.4 -0.4 -0.5 0.3 -0.8 -0.7 -0.2 -0.5 0.1 0.6 -1.7 -1.0 -0.9 0.0
Fed-up feelings 1.7 3.0 6.7 -0.4 2.6 -1.1 2.1 1.5 1.8 2.4 2.0 1.5 2.2 2.0 -2.6 -2.0 -0.3 -0.2 2.5 1.3 1.1 2.3 1.4 2.0 1.6 1.6 1.0 0.6 0.5 2.1 2.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 6.2 -1.1 0.5 -2.5 -0.2 -0.0 -0.7 -0.2 0.1 -0.4 0.7 -0.5 -0.2 -0.6 0.4 -1.8 0.4 1.0 2.0 0.4 0.1 0.5 0.1 0.6 0.3 -1.1 -1.9 -0.2 1.3
Relative age voice broke 0.8 1.2 4.1 -0.1 -0.2 0.7 -0.7 -0.8 -0.8 -1.5 -1.0 -1.2 -1.5 -0.7 1.8 0.8 -2.0 0.0 -1.3 0.1 -0.1 -0.8 -1.1 -1.7 -1.4 -1.6 -0.9 -0.2 -0.6 -1.2 -1.2
Taking other prescription medications 0.8 1.2 4.6 -0.6 1.7 -0.6 0.9 0.7 0.7 1.6 1.0 0.4 2.1 1.1 -1.8 -1.7 1.1 0.1 1.0 0.2 0.5 1.3 0.8 1.7 0.5 0.6 -0.4 0.1 -0.3 1.7 1.0
Age when periods started (menarche) 0.3 0.7 3.8 -0.2 1.8 1.3 -0.1 -0.5 0.1 -0.5 -0.1 -0.4 -1.2 -0.0 0.5 -1.3 -1.9 -1.1 -0.5 -1.0 -0.2 -0.1 -0.6 -0.9 -0.4 -1.0 -0.0 -0.4 0.3 -0.5 -0.8
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 4.8 -0.4 1.2 1.0 0.4 -0.3 1.1 0.5 0.4 0.2 -0.1 0.9 -0.5 -1.2 -2.2 0.6 0.6 -1.3 -0.8 0.8 0.1 -0.0 0.2 -0.5 -0.1 0.1 0.5 0.7 -0.5
Heel bone mineral density (BMD) T-score, automated (left) 1.5 3.5 6.5 -0.4 -0.6 2.0 -2.2 -2.0 -1.5 -1.8 -2.2 -2.1 -2.5 -1.7 1.9 0.1 -0.1 -1.7 -1.8 -2.3 -1.9 -2.3 -2.3 -2.2 -2.3 -2.5 -1.8 -1.3 -0.4 -1.8 -2.5
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 4.8 0.2 0.4 0.9 -0.9 -1.2 -1.1 -0.8 -1.6 -2.0 -1.1 -0.9 0.7 -0.1 -0.9 -1.3 -1.0 -0.7 -0.7 -0.9 -1.9 -1.5 -2.2 -1.7 -1.6 -1.4 -1.3 -1.1 -1.5
Qualifications: CSEs or equivalent 0.3 0.4 1.5 -0.3 -0.4 -1.2 -0.7 -0.6 -0.6 0.5 -0.1 -0.2 0.8 -0.7 -0.8 0.2 0.8 -1.2 0.3 0.2 0.3 -0.0 -0.0 0.3 0.1 1.1 0.8 -1.1 -0.5 -0.1 0.5
Serious illness, injury or assault to yourself 1.1 1.4 7.0 0.3 0.6 1.3 -1.1 -1.0 -0.9 0.3 -1.4 -1.3 -0.8 -0.7 -0.2 -0.3 1.5 -0.0 -0.4 -1.8 -2.6 -1.1 -1.4 -0.3 -1.6 -1.7 -1.3 -1.1 0.1 0.0 -2.0
High blood pressure 1.1 3.0 6.9 0.7 2.6 -1.2 1.9 1.7 2.0 1.2 2.4 1.9 2.1 1.7 -1.2 -2.4 0.3 -0.3 1.3 1.0 2.3 2.1 2.1 1.9 2.1 1.9 0.8 1.5 0.9 1.8 2.2
Hayfever, allergic rhinitis or eczema 0.3 0.7 4.7 1.1 -0.2 -1.3 0.2 0.9 0.8 -0.5 0.4 0.2 -0.0 0.0 0.5 1.1 -0.2 1.2 -0.3 1.8 2.2 0.6 0.4 -0.6 0.4 0.9 0.6 0.5 -0.4 -0.4 0.9
Multivitamins +/- minerals 0.4 0.5 2.2 -1.0 0.2 0.3 -0.3 -0.7 -0.6 0.8 -0.5 -0.8 0.2 0.2 -0.9 0.6 -0.3 0.8 -0.3 -1.2 -1.5 0.1 -0.7 -0.1 -0.9 -0.3 -0.4 -0.8 0.2 0.5 -0.9
Stomach or abdominal pain in last month 1.7 2.1 6.1 -1.4 1.1 -1.4 1.3 0.7 0.9 2.1 1.4 1.2 2.1 1.5 -2.3 -1.8 1.8 -0.1 2.2 0.2 -0.0 1.4 1.3 2.5 1.5 1.8 0.6 -0.0 0.3 1.7 1.4
Supplements: Glucosamine 0.1 0.2 0.8 0.4 -0.9 0.0 -0.3 0.3 -0.6 -0.6 -0.1 0.2 -0.5 -0.2 0.9 0.5 -0.5 0.5 -0.5 -0.1 -0.5 -0.4 0.3 -0.3 0.2 0.1 0.2 0.4 0.5 -0.2 -0.4
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.6 -0.3 -0.7 -1.2 -0.8 -1.0 -0.3 -0.2 -0.5 -0.8 0.4 -0.6 -0.1 0.5 -0.1 -1.0 0.6 -0.6 0.3 -0.4 -0.6 0.5 -0.5 -0.1 -0.3 -1.2 -1.0 -0.4 -0.2
Medication: Atenolol 0.2 0.3 2.7 -0.6 1.6 0.5 0.2 0.3 0.8 -0.1 0.2 0.0 -0.4 0.1 0.2 -0.9 -1.1 0.1 -0.4 -0.2 -0.0 0.1 0.0 -0.5 -0.1 -0.4 -0.2 0.3 0.3 0.2 -0.2
Medication: Levothyroxine sodium 0.5 0.9 2.4 -0.7 -0.3 0.7 -0.6 -0.9 -1.3 -0.4 -1.2 -1.4 -1.1 -0.9 0.3 0.4 -0.5 -0.4 -0.5 -0.7 -0.7 -0.9 -1.5 -1.2 -1.6 -1.5 -0.3 -1.3 -1.1 -0.8 -1.0
Sitting height 0.1 0.9 5.3 -2.2 -0.3 -0.1 -0.7 -1.2 -0.7 0.3 -0.7 -0.6 0.1 -0.8 -0.6 -1.7 1.3 -0.5 0.2 -2.3 -0.8 -1.1 -0.6 0.5 -0.5 -0.1 1.1 -1.3 -0.6 -0.3 -0.1
Chronic bronchitis/emphysema (father) 2.0 2.4 5.9 -2.0 -0.4 -0.8 -1.8 -2.0 -2.4 -1.3 -1.4 -1.6 -1.3 -2.2 0.8 -0.0 1.9 -2.1 -1.6 -0.7 0.8 -1.9 -1.5 -1.2 -1.2 -0.6 -0.7 -2.3 -2.3 -1.5 -0.4
High blood pressure (mother) 0.7 0.9 3.5 0.2 1.5 -1.2 0.5 -0.4 -0.6 1.5 0.6 -0.1 1.7 0.7 -1.9 -1.8 0.3 -1.6 0.3 -0.1 1.0 1.2 0.1 0.7 -0.0 0.1 0.7 -0.9 -0.5 0.7 1.0
Body mass index (BMI) 0.2 0.9 2.6 1.4 -1.6 -1.5 -1.0 -0.4 -0.1 -1.3 -0.9 -0.6 0.8 -0.8 1.2 1.6 1.4 0.6 -0.9 0.0 0.7 -1.0 -0.0 0.7 -0.5 0.2 -1.4 0.3 -0.9 -0.2 0.0
Impedance of leg (left) 0.3 1.2 4.3 -0.1 1.5 2.1 1.2 1.2 0.2 1.9 1.1 0.9 -0.5 1.4 -1.9 -1.1 -0.8 -0.6 1.4 0.0 -1.7 1.3 0.2 -0.2 0.7 -0.4 1.1 -0.0 1.5 1.0 -0.3
Leg predicted mass (left) 0.3 1.4 5.0 -0.6 -1.9 -1.9 -1.5 -1.5 -0.7 -1.6 -1.1 -1.0 0.2 -1.6 1.3 0.4 2.2 -0.1 -1.1 -0.9 1.3 -1.6 -0.6 0.2 -0.7 0.4 -0.4 -0.8 -1.7 -1.0 0.2
Trunk fat mass 0.1 0.4 1.6 0.9 -0.9 -0.8 -0.1 0.5 0.7 -0.3 0.2 0.4 0.9 0.2 0.3 0.4 1.3 1.0 0.3 -0.1 0.5 -0.2 0.6 1.2 0.5 0.6 -0.3 0.6 0.0 0.5 0.5
Waist circumference 0.1 0.4 2.8 1.7 -0.6 -0.6 -0.0 0.4 0.8 -0.4 0.2 0.3 0.8 0.3 0.4 0.3 1.0 0.7 0.3 0.2 0.7 0.1 0.6 0.9 0.4 0.4 -0.8 0.8 0.0 0.5 0.4
Number of incorrect matches in round 1.7 2.8 7.7 -0.4 -1.2 2.6 -1.4 -1.5 -1.7 -1.7 -1.6 -1.2 -2.8 -1.0 1.9 1.1 -0.2 -1.1 -1.5 -1.9 -2.1 -1.9 -1.5 -1.9 -1.4 -2.5 -1.7 -0.7 -0.0 -1.6 -2.5
Past tobacco smoking 1.7 3.1 5.8 0.6 2.4 0.2 2.0 1.8 2.2 2.3 2.1 1.7 2.1 2.0 -2.2 -2.0 -0.6 1.2 1.5 1.5 0.4 2.3 1.6 1.6 1.5 1.7 1.1 1.7 2.1 2.4 1.4
Alcohol usually taken with meals 1.8 2.9 8.2 -0.4 -0.1 -2.6 0.7 1.2 0.6 1.4 1.8 1.4 2.2 0.7 -1.9 -0.5 -2.3 0.2 1.4 2.1 2.8 2.2 1.7 0.6 1.9 2.9 2.8 0.1 -0.0 0.6 2.6
Nervous feelings 2.6 4.8 12.0 0.8 3.5 -0.5 2.0 2.0 2.4 2.2 2.6 2.1 2.3 2.0 -2.4 -2.0 -2.7 -0.1 2.7 2.6 1.4 3.0 2.2 1.5 2.4 2.7 2.4 1.2 1.6 1.9 2.5
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 6.0 -2.5 1.5 -0.7 -0.1 -0.5 -1.0 0.6 -0.1 -0.6 0.1 -0.1 -1.0 -0.4 0.8 -1.8 1.0 -0.1 0.2 0.0 -0.5 0.6 -0.4 -0.3 0.0 -1.8 -1.1 0.1 0.2
Hearing difficulty/problems with background noise 0.1 0.2 1.8 -0.2 -0.4 -0.7 -0.5 -0.1 -0.4 -0.2 -0.2 -0.0 -0.5 -0.4 0.1 1.0 -0.3 -0.3 -0.1 -0.2 -0.4 -0.5 -0.1 -0.1 0.1 -0.2 1.4 -0.6 -0.2 -0.5 -0.0
Hair/balding pattern: Pattern 2 0.4 0.4 2.2 -1.1 -0.4 1.4 -0.5 -0.3 -0.1 0.3 -0.4 -0.4 -0.5 0.1 -0.4 0.3 0.5 -1.0 -0.3 -1.0 -1.5 -0.0 -0.5 -0.5 -0.6 -0.5 -0.9 -0.3 0.2 0.2 -1.2
Had menopause 0.5 0.6 2.7 0.4 1.0 1.6 0.5 0.5 1.2 0.5 0.7 0.6 -0.1 0.9 -0.4 -0.8 -1.6 -0.1 1.2 0.2 -0.6 0.5 0.6 0.0 0.4 -0.5 -0.3 0.9 1.3 0.6 -0.4
Had other major operations 0.5 0.6 1.5 0.8 -0.8 0.2 -1.1 -0.7 -0.5 -1.1 -1.0 -0.6 -0.7 -1.2 1.2 0.8 -0.1 1.0 -1.2 0.0 -0.5 -1.1 -0.5 -0.8 -0.6 0.1 -0.6 -0.1 -0.1 -1.1 -0.6
Forced vital capacity (FVC) 0.1 0.6 4.9 0.6 -2.2 -0.8 -0.2 -0.1 -0.1 -0.4 -0.2 0.6 0.3 -0.6 0.5 1.3 -0.3 0.6 0.0 -0.4 -0.5 -0.9 0.6 0.8 0.6 0.8 1.6 0.5 0.5 -0.5 0.4
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.6 3.9 0.0 -0.4 1.6 -1.5 -1.2 -1.0 -1.1 -1.5 -1.2 -1.4 -1.0 1.2 -0.0 0.1 -1.1 -0.9 -1.6 -1.8 -1.5 -1.4 -1.3 -1.4 -2.0 -1.5 -0.6 0.1 -1.0 -1.9
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 2.5 0.1 0.1 0.6 -1.1 -0.8 -0.6 -0.5 -1.1 -1.2 -0.6 -0.9 0.4 -0.3 -0.3 -1.6 -0.0 -0.3 -0.5 -0.6 -1.1 -1.0 -1.2 -1.0 -1.0 -1.2 -0.8 -0.8 -1.0
Qualifications: None of the above 0.3 0.7 3.1 0.7 -0.4 -0.1 -0.1 -0.0 -0.7 -1.4 -0.8 -0.3 -1.2 -0.5 1.8 1.7 1.2 -0.5 -0.9 -0.5 -0.2 -1.3 -0.3 -0.0 -0.5 -0.9 -0.9 0.3 -0.6 -0.7 -0.4
Financial difficulties in last 2 years 1.5 2.0 4.2 -1.8 -0.2 -0.4 -1.5 -1.6 -1.4 -1.0 -1.6 -1.9 -1.3 -1.4 0.7 0.4 1.2 -1.6 -1.6 -1.2 -0.3 -1.1 -1.9 -1.2 -1.7 -1.8 -1.8 -2.0 -2.1 -1.0 -1.2
Mouth/teeth dental problems 0.1 0.1 1.3 -0.5 0.2 0.2 -0.0 0.2 -0.7 0.4 -0.1 -0.2 0.1 -0.3 -0.4 0.5 1.1 0.4 -0.2 0.2 -0.1 -0.1 -0.4 0.0 -0.3 -0.4 0.2 -0.4 0.0 -0.0 0.1
Heart attack 0.3 0.4 3.8 -0.7 1.0 0.5 -0.1 -0.5 -0.7 0.5 -0.3 -0.4 0.2 -0.1 -0.4 -1.9 1.0 -0.7 -0.3 -0.8 -0.8 -0.7 -0.4 0.5 -0.7 -0.6 -0.4 -0.3 0.1 0.3 -0.5
Allergy 0.2 0.4 3.5 -0.4 0.6 0.6 0.2 -0.6 -0.7 0.4 0.0 0.1 0.1 0.2 -0.3 -1.2 -0.7 -1.9 -0.1 -1.6 -1.1 -0.1 -0.0 0.3 0.0 -0.5 0.2 -0.1 0.2 0.3 -0.1
Pain all over the body in last month 1.0 1.1 4.0 1.4 0.7 -0.3 1.5 1.6 1.4 0.2 1.0 1.3 0.6 1.3 0.1 0.3 0.0 2.0 0.2 0.8 0.1 0.7 1.2 1.0 1.2 0.8 0.3 1.9 0.9 1.0 0.8
Diabetes (self-reported) 0.2 0.4 2.2 -1.5 0.9 -0.8 0.3 -0.4 0.2 0.6 0.2 -0.3 0.7 0.5 -0.8 -0.9 0.2 -0.1 0.8 -0.2 0.2 0.8 -0.2 0.4 -0.1 -0.6 -0.6 -0.6 -0.7 0.6 0.1
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 4.6 -0.1 1.7 -1.0 0.7 0.7 0.8 0.7 0.9 0.5 0.2 0.4 -0.9 -0.7 0.3 0.4 0.0 1.7 2.1 1.0 0.4 -0.2 0.7 1.7 1.3 -0.1 -0.2 0.3 1.5
Medication: Ramipril 0.6 0.8 4.2 -2.0 0.4 0.3 -1.0 -0.7 -1.4 -0.6 -0.8 -1.0 -0.8 -1.1 0.5 0.0 0.8 -1.1 -1.2 -1.0 0.1 -1.0 -1.1 -0.9 -1.0 -0.4 -0.2 -1.1 -0.6 -0.8 -0.6
Medication: Simvastatin 1.4 2.0 4.9 0.8 1.8 -0.9 1.8 1.3 1.8 1.2 1.9 1.5 1.6 2.0 -1.2 -1.4 -0.5 -0.6 1.3 1.3 1.4 2.2 1.6 1.2 1.5 1.0 0.4 1.4 0.8 1.7 1.4
Fluid intelligence score 1.8 3.8 11.2 -1.1 2.0 -2.5 1.6 1.4 0.8 2.2 2.0 1.5 3.4 1.2 -2.6 -1.9 0.5 -0.5 1.3 2.5 2.6 2.4 1.9 2.0 1.9 2.7 1.7 0.7 -0.0 1.9 3.2
Illnesses of siblings 0.4 0.6 3.7 0.3 -1.2 -1.1 0.6 -0.1 0.4 -0.4 0.2 0.6 0.4 0.2 0.5 0.6 -0.3 1.9 1.0 0.2 0.9 -0.3 0.6 1.0 0.7 1.1 1.0 0.6 -0.0 -0.4 0.8
Neuroticism score 1.9 3.9 8.9 -0.1 3.0 -0.8 1.9 1.6 2.0 2.7 2.1 1.7 2.3 1.9 -2.9 -1.9 -2.8 -0.1 2.9 1.5 0.6 2.8 1.8 1.7 1.8 2.0 2.3 0.4 1.4 1.9 1.9
Weight 0.2 0.9 4.7 0.1 -1.8 -1.6 -1.1 -0.8 -0.6 -1.1 -0.9 -0.7 0.5 -1.1 0.9 0.6 2.2 0.2 -0.8 -0.7 0.8 -1.4 -0.3 0.7 -0.4 0.3 -0.4 -0.4 -1.2 -0.5 0.2
Impedance of arm (right) 0.7 3.1 6.9 -0.8 2.3 1.3 2.0 2.4 2.2 2.3 2.5 1.9 0.6 2.2 -2.3 -1.8 -1.2 1.0 2.3 2.0 0.8 2.6 1.4 0.3 2.0 1.2 1.3 1.0 1.5 1.7 1.4
Arm fat percentage (right) 0.1 0.5 1.5 1.2 -0.8 -0.8 -0.3 0.6 0.8 -0.7 0.1 0.2 0.8 0.1 0.7 1.2 0.8 0.9 -0.1 0.6 1.0 -0.1 0.5 0.7 0.3 0.6 -1.1 0.7 -0.3 0.3 0.4
Trunk fat-free mass 0.3 1.8 8.8 -0.6 -2.4 -1.6 -1.6 -1.8 -1.6 -1.6 -1.4 -1.0 -0.3 -1.7 1.4 0.5 3.0 -0.4 -1.3 -1.4 0.5 -2.2 -0.8 0.3 -0.8 0.0 -0.0 -0.9 -1.5 -1.3 -0.1
Hip circumference 0.2 0.7 4.3 1.4 -1.1 -1.5 -0.2 0.1 0.8 -0.4 0.1 0.4 1.3 -0.2 0.3 -0.1 2.1 0.2 0.1 0.1 1.3 -0.3 0.7 1.3 0.5 1.1 -0.5 0.7 -0.4 0.4 0.9
Time employed in main current job 0.8 0.9 5.5 1.7 -2.3 0.9 0.6 0.6 0.2 -0.5 0.0 0.7 -0.4 0.8 1.0 0.9 0.7 1.0 0.6 -1.1 -1.3 -0.5 0.6 1.0 0.5 -0.3 -0.8 1.5 1.5 0.0 -0.7
Alcohol intake versus 10 years previously 1.9 2.8 6.1 0.1 -0.7 -0.5 -2.0 -2.1 -1.6 -2.5 -1.8 -1.9 -1.9 -1.9 2.4 0.6 1.3 -2.1 -2.4 -1.4 0.5 -2.1 -1.8 -1.4 -1.7 -1.4 -1.4 -1.6 -1.9 -2.0 -1.3
Father’s age at death 0.3 0.3 1.2 0.2 -0.3 -0.1 -0.3 -0.3 -0.9 -0.9 -0.5 -0.4 -0.6 -0.7 1.1 0.4 -0.7 -0.9 -0.6 0.7 0.6 -0.6 -0.4 -0.9 -0.5 -0.2 -0.2 -0.0 -0.3 -1.0 -0.1
Worrier / anxious feelings 1.4 2.6 8.2 -1.1 2.4 0.2 1.1 1.3 1.7 2.5 1.7 1.2 1.5 1.1 -2.9 -2.0 -2.7 -0.2 2.2 1.3 0.0 2.3 1.0 0.5 1.4 1.4 1.9 -0.1 1.2 1.6 1.3
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 4.5 -0.5 -0.4 -0.2 -1.0 -0.7 -1.0 -0.8 -1.0 -1.1 -0.2 -0.6 0.6 0.1 2.1 -0.6 -0.6 -1.0 0.1 -0.9 -0.8 -0.0 -1.0 -1.0 -1.6 -1.0 -1.3 -0.3 -0.5
Falls in the last year 0.3 0.4 4.2 2.0 0.2 -0.1 0.1 0.2 0.7 -0.6 -0.2 -0.1 0.1 0.3 0.7 -0.2 0.2 0.7 0.4 -0.8 -0.0 -0.0 0.2 0.5 -0.2 -0.3 -1.6 0.5 -0.2 0.0 -0.3
Hair/balding pattern: Pattern 3 2.0 3.0 7.5 1.3 -0.3 -1.4 -2.2 -2.1 -1.9 -2.4 -2.1 -1.9 -1.3 -2.7 2.2 1.1 -0.6 -1.7 -2.5 -0.5 0.7 -2.0 -1.7 -1.9 -1.7 -0.9 -0.7 -1.7 -2.2 -2.4 -0.7
Number of live births 0.2 0.3 2.2 -1.5 -0.2 0.4 0.1 -0.5 -0.7 0.2 -0.1 -0.1 -0.6 -0.2 -0.2 -0.1 1.5 -0.5 -0.1 -0.4 -0.5 -0.5 -0.4 0.2 -0.2 -0.6 -0.1 -0.4 -0.0 0.1 -0.1
Forced expiratory volume in 1-second (FEV1) 0.6 2.1 5.2 -0.2 -0.7 0.0 1.4 1.5 1.3 1.6 1.5 1.9 1.4 1.2 -1.3 0.0 -0.6 1.8 1.6 0.3 -1.1 0.8 1.8 2.0 1.8 1.6 2.3 1.7 2.2 1.5 1.1
Pulse rate 0.3 0.5 2.1 1.2 -1.5 -0.4 0.3 0.7 -0.1 -0.4 0.1 0.6 0.7 -0.1 0.7 0.9 0.8 1.0 0.6 1.0 0.4 -0.4 0.7 1.0 0.5 0.8 0.1 0.9 0.4 0.1 0.7
Happiness 2.5 3.0 7.2 0.3 2.2 -2.1 1.4 1.2 1.2 1.9 1.7 1.1 2.7 1.1 -2.2 -1.7 -1.0 0.0 2.1 2.4 2.4 2.1 1.4 1.7 1.5 2.5 2.0 0.2 -0.0 1.3 2.6
Noisy workplace 3.1 3.9 8.9 -0.4 -2.0 2.2 -1.5 -1.2 -2.0 -1.6 -2.2 -1.9 -2.2 -1.2 1.9 2.9 2.2 0.5 -1.2 -2.3 -2.0 -2.6 -2.2 -1.1 -2.3 -3.0 -2.9 -1.0 -0.9 -1.6 -2.5
Qualifications: A levels/AS levels or equivalent 1.2 2.7 5.4 0.9 1.7 -0.9 1.7 2.2 2.2 0.8 1.9 1.6 1.4 1.4 -0.9 -0.5 -2.2 2.0 1.1 2.1 2.0 2.3 1.7 0.5 1.8 2.1 1.5 1.6 0.7 1.2 2.0
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.0 2.2 -1.2 -1.1 0.1 -0.9 -0.5 -0.9 -1.4 -0.9 -0.9 -1.4 -0.9 1.4 0.2 1.1 -1.0 -1.4 -0.7 0.9 -0.9 -0.9 -1.5 -0.8 -0.7 -1.5 -0.5 -1.3 -1.1 -0.7
Mouth/teeth dental problems: Dentures 0.4 0.7 3.1 0.5 -0.1 0.7 -0.4 -0.5 0.1 -1.0 -0.6 -0.4 -0.8 -0.2 1.2 -0.9 -1.5 -0.7 -0.7 -1.1 -1.1 -0.5 -0.2 -0.6 -0.6 -1.5 -1.7 0.2 -0.2 -0.3 -1.3
Asthma 0.5 1.0 2.6 -0.7 -1.1 -0.4 -1.5 -0.8 -0.9 -0.9 -1.1 -1.4 -0.6 -1.3 0.5 1.2 1.1 0.1 -0.6 0.4 0.5 -0.8 -1.3 -1.0 -1.2 -0.6 -0.5 -1.6 -1.4 -1.1 -0.7
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 3.2 -0.8 -1.5 -0.8 -1.0 -1.3 -1.0 -0.6 -1.3 -1.3 -0.3 -0.9 0.5 1.8 0.7 -0.2 -0.4 -0.3 0.1 -1.1 -1.0 -0.3 -1.2 -0.5 -1.1 -1.4 -1.3 -1.0 -0.8
Medication: Cholesterol lowering 2.5 3.9 9.2 -0.5 3.0 -1.1 2.0 1.7 2.0 2.8 2.3 1.9 2.9 2.0 -2.9 -2.8 1.1 -0.2 1.4 1.6 0.7 2.4 2.0 2.2 2.0 1.3 0.4 1.4 1.2 3.0 1.9
Depression (self-reported) 2.2 2.6 8.3 -0.3 2.1 -0.8 1.2 1.0 1.0 2.5 1.8 1.2 2.4 1.5 -2.9 -1.6 -1.3 0.8 2.2 0.8 0.2 2.5 1.3 1.7 1.4 1.4 1.8 0.1 1.0 2.1 1.4
Medication: Lansoprazole 0.8 0.9 3.1 1.3 0.4 1.7 0.6 0.5 1.3 0.7 0.8 0.9 0.7 1.0 -0.4 -0.8 -0.7 1.8 0.9 -0.2 -0.8 0.5 0.9 0.9 0.7 0.2 -0.5 1.3 1.6 0.9 -0.2
Prospective memory result 0.6 0.8 3.5 1.0 -0.6 1.5 -0.0 -0.2 -0.6 -0.6 -0.7 -0.6 -1.0 0.1 1.0 0.2 -0.1 0.4 -0.2 -1.5 -1.4 -0.8 -0.6 -0.3 -0.9 -1.9 -1.4 0.2 0.3 -0.4 -1.4
Lung cancer (father) 0.9 1.0 3.5 0.3 -1.8 -0.5 -0.9 -0.8 -1.5 -0.9 -1.3 -0.9 -1.0 -1.4 1.0 1.9 0.5 0.4 -0.2 0.0 -0.2 -1.7 -1.0 -0.7 -0.9 -0.7 0.1 -1.1 -1.0 -1.5 -0.5
Illnesses of mother 0.3 0.3 1.9 -0.4 -1.4 0.6 0.1 0.2 -0.2 -0.5 -0.1 0.4 -0.8 -0.0 0.8 0.3 -0.6 0.8 0.2 -0.7 -0.7 -0.7 0.1 0.2 0.3 0.5 0.6 0.7 0.6 -0.4 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.1 4.7 0.2 -1.4 -1.1 0.9 0.9 0.6 0.6 1.0 1.5 0.9 0.5 -0.5 0.4 0.2 1.3 1.0 0.3 -0.1 0.1 1.3 1.7 1.6 1.6 2.2 1.1 1.2 0.6 1.3
Pulse wave Arterial Stiffness index 0.4 0.5 3.3 -0.0 1.6 0.1 0.5 0.7 0.3 0.4 0.4 0.3 0.2 0.5 -0.4 -1.8 -1.3 0.8 0.4 0.8 0.4 0.6 0.3 -0.1 0.3 0.7 0.9 0.3 0.3 0.3 0.6
Impedance of arm (left) 0.4 1.9 4.6 -1.2 2.1 1.5 1.4 1.7 1.6 1.9 1.8 1.3 0.1 1.5 -2.0 -1.4 -1.4 0.6 1.9 1.7 0.4 1.9 0.8 -0.1 1.4 0.7 1.5 0.3 1.3 1.1 1.0
Arm fat mass (right) 0.1 0.5 2.7 0.9 -1.6 -1.0 -0.7 -0.0 0.3 -0.9 -0.4 -0.1 0.7 -0.4 0.9 1.1 1.4 1.0 -0.2 0.0 0.6 -0.7 0.2 0.9 0.0 0.4 -0.9 0.4 -0.5 0.0 0.2
Trunk predicted mass 0.3 1.9 8.8 -0.5 -2.5 -1.6 -1.6 -1.7 -1.6 -1.6 -1.4 -1.0 -0.3 -1.8 1.5 0.6 3.0 -0.4 -1.3 -1.4 0.5 -2.3 -0.8 0.3 -0.8 0.0 -0.1 -0.9 -1.6 -1.3 -0.1
Standing height 0.1 1.0 5.8 -2.4 -0.9 -0.5 -0.4 -0.8 -0.9 0.1 -0.2 -0.2 -0.7 -0.9 -0.4 -1.9 1.7 -0.7 0.2 -1.4 0.3 -1.1 -0.5 0.1 0.1 0.2 2.1 -1.4 -0.7 -0.7 0.5
Length of working week for main job 1.7 1.9 5.2 -0.4 -1.4 -1.2 -2.2 -1.7 -1.6 -1.6 -1.5 -1.5 -1.0 -2.3 1.3 1.7 0.3 -0.6 -1.3 0.2 0.8 -1.5 -1.5 -1.5 -1.0 0.0 -0.2 -1.9 -1.8 -2.0 -0.5
Exposure to tobacco smoke at home 1.7 1.9 6.7 0.0 -0.3 2.1 -1.1 -1.3 -1.4 -1.1 -1.4 -1.4 -2.6 -0.9 1.1 0.2 0.1 -0.4 -1.5 -1.8 -1.1 -1.5 -1.9 -1.9 -1.5 -1.7 -0.8 -1.3 -0.7 -1.4 -1.8
Breastfed as a baby 0.2 0.3 1.5 -0.2 0.3 0.2 -0.5 -0.5 -0.4 -0.9 -0.4 -0.2 -0.7 -0.3 1.0 0.8 0.3 1.2 -0.1 0.4 0.0 -0.6 -0.2 -0.5 -0.3 -0.3 -0.6 0.0 -0.3 -0.4 -0.3
Tense / ‘highly strung’ 5.5 9.2 16.9 1.7 3.1 -0.2 3.4 3.4 3.8 3.3 3.6 3.4 3.3 3.7 -3.2 -2.3 -3.2 1.2 4.1 2.2 0.4 3.9 3.4 3.0 3.5 2.7 2.6 2.8 3.2 3.3 2.6
Seen doctor (GP) for nerves, anxiety, tension or depression 1.2 1.8 9.7 0.5 3.0 -0.8 0.5 0.4 1.8 1.0 1.2 0.6 1.4 1.0 -1.4 -2.2 -3.1 -0.9 1.1 0.7 1.1 2.1 1.0 0.2 0.9 1.0 1.0 -0.1 0.2 1.0 1.0
Hair/balding pattern: Pattern 4 0.1 0.3 1.3 -0.7 -0.2 1.1 0.4 0.6 0.7 0.3 0.3 0.2 -0.3 0.8 -0.2 0.6 -0.9 -0.2 0.5 -0.2 -0.7 0.4 -0.0 -0.1 0.0 -0.7 -0.7 0.3 0.5 0.3 -0.5
Birth weight of first child 1.8 3.2 6.7 0.7 0.2 -1.0 2.1 2.6 0.5 2.1 2.0 2.3 2.1 1.4 -1.8 -0.5 0.9 2.2 0.7 2.1 0.3 1.3 2.2 2.2 2.2 2.3 2.4 1.9 1.7 1.8 2.5
Peak expiratory flow (PEF) 1.5 3.4 6.1 -0.9 0.2 -0.5 1.7 1.7 1.8 2.3 2.1 2.2 2.2 1.7 -2.3 -1.2 -0.7 2.4 2.2 1.2 -0.1 2.1 2.1 2.1 2.2 2.2 2.5 1.8 2.3 2.3 1.7
Pulse wave reflection index 0.6 0.8 2.9 -0.5 1.7 -0.4 0.7 0.7 0.9 0.7 1.0 0.6 0.6 0.9 -0.9 -1.6 -1.5 1.0 0.4 0.7 0.8 1.4 0.8 -0.1 0.7 1.0 0.5 0.5 0.2 0.7 0.8
Ever highly irritable/argumentative for 2 days 0.3 0.3 2.3 1.5 0.3 0.2 0.4 0.2 0.3 0.8 0.2 0.0 0.9 0.6 -0.9 0.8 -0.4 -0.8 0.6 0.1 -0.2 0.9 0.1 0.6 0.0 -0.2 -0.1 -0.1 0.2 0.5 0.1
Loud music exposure frequency 0.7 0.7 5.2 1.7 -0.3 0.6 -0.1 0.4 0.9 -1.0 -0.2 -0.1 -1.3 -0.2 1.1 0.6 -2.3 1.2 -0.5 0.6 0.2 -0.0 -0.2 -1.5 -0.1 -0.6 -0.4 0.5 -0.3 -0.6 -0.6
Qualifications: O levels/GCSEs or equivalent 0.9 1.4 5.5 0.5 0.8 -1.2 0.5 0.5 0.7 0.6 1.2 1.0 0.9 0.3 -0.9 -1.0 -1.3 0.1 1.4 2.3 2.2 1.4 0.9 -0.1 1.3 2.1 2.2 0.2 -0.0 0.1 1.7
Mouth/teeth dental problems: Bleeding gums 2.5 3.2 12.2 0.4 -0.3 -1.6 1.3 1.5 1.0 2.0 1.9 2.0 2.3 1.0 -2.2 -0.4 -0.3 1.4 2.2 2.2 1.2 1.7 1.9 1.6 2.3 3.1 3.5 0.9 1.3 1.2 2.5
Blood clot in the leg (DVT) 0.6 0.8 9.0 -1.1 0.3 0.6 -0.6 -1.1 -0.8 0.2 -0.8 -0.8 -0.4 -0.5 -0.3 -0.6 3.0 0.4 -0.2 -0.9 -0.5 -1.1 -1.0 0.3 -0.9 -0.1 -1.0 -1.0 -0.6 -0.2 -0.6
Medication: Paracetamol 1.8 2.9 5.1 -0.2 -1.1 -0.4 -1.6 -2.1 -2.0 -2.1 -2.0 -1.9 -2.0 -1.5 2.0 1.2 -0.2 -1.7 -1.9 -1.9 -0.4 -1.7 -1.7 -1.9 -1.8 -1.8 -2.0 -1.7 -2.3 -1.9 -1.7
Headache pain in last month 4.4 7.5 12.7 -2.3 -0.7 0.9 -3.0 -3.3 -2.7 -2.2 -3.4 -3.4 -2.9 -3.0 1.9 1.1 2.1 -2.9 -3.2 -2.3 -1.2 -3.0 -3.6 -2.9 -3.4 -3.0 -3.5 -3.2 -3.0 -2.6 -3.0
Medication for cholesterol, blood pressure or diabetes 3.5 5.9 14.6 0.5 -3.8 0.9 -2.8 -2.3 -2.1 -3.2 -3.0 -2.4 -3.4 -2.8 3.2 3.3 -0.3 -0.6 -2.4 -1.8 -1.1 -3.0 -2.6 -2.9 -2.4 -1.7 -0.9 -1.7 -1.6 -3.4 -2.4
Glaucoma (self-reported) 1.4 1.6 4.0 -0.3 1.5 0.3 1.9 1.4 0.8 2.0 1.4 1.2 1.7 1.8 -1.9 -1.6 -0.5 0.8 1.1 0.0 -0.1 1.8 1.2 1.3 0.9 0.6 0.4 1.1 1.1 1.7 1.0
Gout (self-reported) 0.3 0.4 7.2 2.7 0.4 -0.9 -0.0 0.7 0.1 0.1 0.0 0.0 0.6 0.2 -0.1 -0.5 0.7 -0.9 0.3 -0.2 0.3 0.1 0.3 0.4 -0.0 0.2 -0.1 0.0 -0.0 0.1 0.2
Hypothyroidism/myxoedema (self-reported) 0.7 1.3 3.3 -1.1 -0.7 1.6 -0.7 -1.2 -1.3 -0.7 -1.4 -1.5 -1.3 -0.8 0.7 0.8 0.3 0.0 -0.6 -1.4 -1.1 -1.2 -1.7 -1.1 -1.8 -1.5 -1.3 -1.0 -0.8 -0.8 -1.5
Medication: Amlodipine 1.8 2.5 8.0 -0.1 1.4 -2.0 1.5 0.8 1.2 1.0 1.7 1.2 2.8 1.5 -1.2 -1.5 -0.6 0.5 1.6 1.5 2.7 2.0 1.6 1.9 1.4 2.2 1.0 0.9 -0.1 1.3 2.4
Medication: Ventolin 100micrograms inhaler 0.9 1.1 3.9 -0.9 -2.0 -0.7 -1.2 -1.3 -1.1 -1.1 -1.2 -1.2 0.0 -1.1 0.8 0.9 1.9 -0.8 0.2 -0.2 0.5 -1.2 -0.9 0.4 -1.1 -0.5 -1.1 -1.3 -1.5 -1.0 -0.3
Birth weight 0.3 0.7 4.9 0.6 -1.8 -0.9 -0.6 -0.1 -1.3 -0.7 -1.0 -0.6 -0.2 -1.1 0.8 2.2 0.3 -0.6 -0.3 0.5 0.3 -1.0 -0.4 -0.1 -0.5 0.0 0.0 -0.8 -1.0 -1.1 0.2
Chronic bronchitis/emphysema (mother) 0.6 0.7 1.8 -0.3 0.2 -0.1 -0.8 -0.8 -0.6 -0.8 -0.8 -0.8 -0.8 -1.1 0.7 1.4 -1.2 1.2 -1.1 0.9 0.3 -0.7 -0.7 -1.2 -0.8 -0.2 -0.2 -0.6 -0.8 -1.1 -0.3
High blood pressure (siblings) 0.4 0.5 6.6 0.8 1.7 -0.0 0.3 0.9 0.2 0.3 0.4 0.0 0.2 0.3 -0.4 -1.0 0.3 -2.6 -0.7 0.6 0.6 0.7 0.1 -0.4 0.1 -0.3 -0.5 -0.0 -0.2 0.5 0.3
Forced vital capacity (FVC), Best measure 0.3 1.0 8.2 0.4 -2.9 -1.8 -0.7 -0.6 -0.6 -1.3 -0.5 0.2 -0.1 -1.2 1.4 1.8 0.1 0.5 -0.4 -0.1 0.3 -1.4 0.3 0.5 0.5 0.9 1.5 0.2 -0.3 -1.2 0.6
Body fat percentage 0.1 0.5 2.2 1.5 -0.4 -0.4 0.1 1.0 1.1 -0.1 0.5 0.6 0.9 0.5 0.1 0.7 0.6 1.2 0.4 0.5 0.3 0.2 0.8 1.1 0.7 0.6 -0.4 1.0 0.5 0.8 0.5
Leg fat percentage (right) 0.2 0.6 3.6 1.9 -0.6 -0.5 0.1 1.1 0.6 -0.3 0.3 0.6 0.9 0.5 0.3 1.4 0.3 1.3 0.2 0.8 0.2 0.2 0.8 0.9 0.6 0.6 -0.5 1.2 0.5 0.7 0.4
Arm fat-free mass (right) 0.4 2.2 6.1 -0.3 -2.4 -1.1 -1.9 -2.0 -1.8 -1.8 -1.9 -1.4 -0.8 -1.9 1.6 0.6 2.1 -0.6 -1.5 -2.0 -0.2 -2.5 -1.2 -0.2 -1.2 -0.6 -0.2 -1.3 -1.6 -1.5 -0.7
Exposure to tobacco smoke outside home 5.8 7.7 16.5 -2.3 -2.3 -1.3 -3.3 -4.1 -3.2 -2.9 -3.2 -3.2 -2.4 -3.4 2.5 1.6 2.4 -2.8 -3.4 -1.9 1.1 -3.3 -3.0 -2.5 -2.9 -1.5 -2.1 -3.3 -3.8 -3.3 -1.4
Comparative body size at age 10 0.2 0.6 2.5 1.6 -1.2 -1.6 -0.1 1.2 0.1 -0.8 -0.3 0.1 0.4 -0.6 0.8 1.2 -0.4 0.0 -0.6 0.9 0.8 -0.3 0.3 0.1 0.3 1.0 -0.2 0.3 -0.7 -0.4 0.6
Number of full brothers 0.9 1.1 3.3 -0.2 -1.1 0.6 -1.0 -1.0 -1.3 -0.8 -1.3 -0.9 -1.1 -1.0 0.9 1.6 1.8 -1.4 -1.2 -1.1 -1.0 -1.6 -0.8 -0.3 -1.1 -1.1 -0.5 -0.7 -0.5 -0.9 -0.9
Worry too long after embarrassment 1.3 2.2 5.4 0.8 0.7 1.4 1.8 1.9 1.3 1.9 1.4 1.7 1.0 1.7 -1.6 -0.2 -1.9 1.8 2.1 1.1 -1.1 1.4 1.5 1.3 1.4 1.4 1.7 1.2 2.3 1.4 0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.7 4.3 -0.3 2.1 -0.6 0.1 -0.5 0.3 1.1 0.4 -0.2 1.0 0.4 -1.5 -1.5 -1.4 -0.7 0.9 -0.5 0.3 1.0 -0.1 0.6 -0.0 0.2 1.2 -1.2 -0.2 0.5 0.5
Wheeze or whistling in the chest in last year 1.8 3.1 10.2 -0.8 -1.1 -2.2 -2.1 -1.6 -2.0 -2.1 -1.9 -2.1 -0.7 -2.3 1.7 1.9 2.5 -1.7 -1.5 -0.1 1.7 -2.0 -1.6 -0.8 -1.7 -0.4 -0.9 -2.3 -3.2 -2.1 -0.1
Number of children fathered 1.1 1.2 6.6 1.0 0.9 2.0 1.0 0.7 1.5 1.0 0.2 0.3 0.3 1.2 -0.6 -0.3 -0.6 1.4 1.0 -0.8 -2.6 0.4 0.3 0.8 -0.2 -1.6 -1.4 1.0 1.4 1.4 -1.1
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 2.9 0.0 -0.2 -0.9 -0.9 -0.6 -1.0 -0.6 -0.5 -0.6 -0.3 -1.1 0.3 0.6 -0.8 -0.9 -1.0 0.4 1.7 -0.5 -0.5 -1.1 -0.3 0.3 1.2 -1.2 -1.3 -1.2 0.6
Age at first live birth 2.4 4.2 13.5 2.1 0.2 -1.2 1.5 2.6 2.0 1.1 2.0 2.3 2.0 1.0 -1.0 0.2 -3.2 2.5 1.2 3.7 1.5 2.3 2.4 0.6 2.4 3.0 2.5 2.2 1.7 1.3 2.3
Pulse wave peak to peak time 0.5 0.5 2.8 -0.3 -1.7 -0.4 -0.6 -0.8 -0.6 -0.2 -0.5 -0.4 -0.1 -0.7 0.3 1.5 1.7 -0.9 -0.5 -0.9 -0.3 -0.7 -0.4 0.2 -0.3 -0.6 -0.7 -0.6 -0.5 -0.3 -0.5
Health satisfaction 0.7 0.9 4.9 -1.5 1.2 -0.4 0.2 0.2 0.4 1.8 0.7 0.1 1.6 0.6 -2.2 -0.7 0.3 0.4 1.2 1.0 0.4 1.4 0.1 0.8 0.3 0.9 0.3 -0.6 -0.2 1.4 0.8
Shortness of breath walking on level ground 0.2 0.3 1.1 0.9 0.5 -0.3 0.6 1.0 -0.2 0.5 0.1 0.0 0.9 0.5 -0.4 -0.2 -0.0 0.8 0.6 0.2 -0.5 0.3 0.3 0.9 -0.1 -0.1 -0.4 0.4 -0.1 0.6 0.1
Qualifications: College or University degree 0.9 2.7 5.7 -0.4 1.2 -1.4 1.3 1.6 1.4 1.6 1.9 1.5 2.4 1.2 -1.8 -0.9 -1.8 2.1 0.2 1.7 1.9 2.4 1.6 0.9 1.8 2.2 2.4 1.1 0.7 1.5 2.4
Eye problems/disorders: None of the above 0.8 0.9 1.8 0.5 0.4 -0.6 1.2 1.2 1.0 0.6 1.3 1.3 0.8 1.2 -0.5 -0.8 0.3 1.0 0.7 1.2 0.4 1.1 1.3 1.1 1.3 0.6 0.7 1.3 0.6 1.1 0.9
Mouth/teeth dental problems: Loose teeth 0.2 0.2 1.2 -0.3 -0.6 -0.6 -0.2 -0.3 0.6 -0.3 -0.0 0.3 -0.0 -0.0 0.3 1.1 -0.4 1.1 0.5 -0.5 -0.3 -0.2 0.4 0.4 0.5 0.4 0.4 0.0 0.3 -0.4 -0.0
Emphysema/chronic bronchitis 1.1 1.2 3.5 -1.1 -0.6 1.6 1.2 0.7 0.4 1.8 0.8 0.6 0.8 1.4 -1.7 0.2 0.2 1.6 1.7 -0.1 -1.9 1.2 0.5 1.3 0.3 -0.1 -0.2 0.6 1.4 1.6 -0.3
Medication for pain relief, constipation, heartburn 0.4 0.7 4.0 0.2 -0.6 -0.0 0.1 0.8 0.5 -0.0 0.7 0.9 0.2 -0.0 0.1 1.1 0.5 1.0 0.2 2.0 0.7 0.3 0.7 0.1 1.0 1.1 1.7 1.0 1.1 0.1 0.9
Neck or shoulder pain in last month 2.4 3.3 7.6 -1.3 -0.7 -0.5 -2.2 -2.8 -1.5 -1.4 -2.2 -2.4 -1.7 -1.9 1.1 1.0 0.8 -2.4 -1.8 -2.1 -0.3 -1.8 -2.3 -1.8 -2.2 -1.7 -2.0 -2.6 -2.0 -1.8 -1.8
Medication: Blood pressure 1.9 3.4 10.1 0.4 3.2 -0.6 2.0 1.8 1.6 2.4 2.2 1.7 2.7 2.1 -2.4 -2.9 0.5 0.5 1.6 0.5 0.3 2.2 1.8 2.4 1.8 1.2 0.6 1.2 1.4 2.7 1.6
Angina (self-reported) 0.6 0.8 3.3 0.2 1.8 0.1 1.2 1.1 0.9 0.7 1.0 0.7 1.0 1.0 -0.5 -1.3 -0.0 -0.7 1.1 0.5 0.4 0.8 0.9 1.3 0.6 0.3 -0.1 0.9 0.7 1.1 0.6
Migraine (self-reported) 0.6 0.7 4.7 1.8 0.1 0.7 -0.1 0.2 0.0 -0.7 -0.7 -0.5 -0.4 -0.3 1.1 1.0 0.1 0.6 -0.2 -0.3 -1.8 -0.7 -0.4 0.1 -0.7 -0.9 -2.2 0.4 0.2 0.1 -1.4
Medication: Ibuprofen 0.4 0.5 3.3 -0.2 -1.4 -1.6 -0.1 -0.5 -0.4 -0.2 -0.6 -0.4 0.4 -0.5 0.2 1.8 0.5 0.7 0.3 0.6 0.3 -0.7 -0.1 0.4 -0.4 0.1 -0.2 -0.7 -0.9 -0.5 0.1
Medication: Allopurinol 1.0 1.4 10.0 3.2 0.7 -0.8 0.8 1.6 1.2 1.0 1.1 1.0 1.6 1.1 -1.0 -0.4 0.7 -0.1 1.0 0.6 0.7 1.1 1.2 1.4 1.0 1.3 0.7 0.9 0.9 1.1 1.1
Medication: Omeprazole 0.3 0.4 2.5 -1.2 1.5 0.5 -0.0 -0.2 0.4 0.3 -0.0 -0.4 0.4 0.4 -0.4 -0.4 -0.2 -0.9 0.7 -0.4 -0.1 0.6 -0.2 0.0 -0.3 -0.2 -1.6 -0.4 -0.6 0.5 -0.2
Medication: Seretide 50 evohaler 1.0 1.2 3.7 -0.7 -0.2 1.9 -1.1 -0.9 -0.8 0.1 -1.1 -1.2 -0.7 -0.6 -0.2 0.0 0.5 -1.6 0.5 -1.3 -1.9 -1.1 -1.3 -0.3 -1.3 -1.5 -1.3 -1.4 -0.1 -0.3 -1.7
Mean time to correctly identify matches 3.1 5.9 16.3 0.1 -0.3 2.3 -2.6 -2.3 -2.5 -2.8 -2.6 -2.6 -4.0 -2.5 2.8 0.7 -0.5 -2.3 -2.6 -2.1 -1.1 -2.9 -3.0 -3.2 -2.6 -2.9 -1.6 -2.2 -2.0 -2.9 -2.8
Heart disease (mother) 1.3 1.6 5.1 -1.4 0.4 -1.1 -1.4 -1.6 -1.1 -1.1 -1.0 -1.3 -1.1 -1.6 0.8 0.4 2.2 -1.9 -1.0 -0.1 1.1 -1.3 -1.4 -1.0 -0.9 -0.9 -0.3 -2.0 -2.1 -1.3 -0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 5.3 0.8 0.2 -1.5 0.1 0.4 0.1 0.1 0.1 0.1 1.0 -0.0 -0.2 -0.2 2.3 -1.7 0.8 1.4 0.7 -0.0 0.4 1.0 0.2 0.9 -0.7 -0.0 -0.7 0.3 0.7
Whole body fat mass 0.1 0.4 2.1 1.2 -1.2 -0.9 -0.3 0.4 0.4 -0.6 -0.0 0.2 0.8 -0.1 0.5 0.6 1.4 0.9 0.0 -0.1 0.5 -0.5 0.5 1.1 0.4 0.6 -0.4 0.6 -0.1 0.3 0.4
Leg fat mass (right) 0.1 0.4 2.5 1.6 -1.1 -0.7 -0.2 0.5 0.4 -0.6 -0.0 0.2 0.8 0.1 0.6 0.8 1.0 1.1 0.0 0.1 0.3 -0.3 0.5 1.0 0.3 0.4 -0.8 0.9 0.0 0.4 0.2
Arm predicted mass (right) 0.3 1.6 4.5 -0.2 -2.1 -1.5 -1.6 -1.8 -1.6 -1.5 -1.5 -1.2 -0.3 -1.8 1.3 0.3 2.1 -0.5 -1.3 -1.6 0.2 -2.1 -0.9 0.1 -0.9 -0.2 0.0 -1.1 -1.5 -1.3 -0.3
Pulse rate, automated reading 1.1 3.6 11.4 3.4 -0.4 -0.5 1.7 2.2 2.2 0.7 1.8 2.3 2.7 1.7 -0.4 -0.2 1.5 1.6 2.0 1.3 0.7 1.3 2.6 2.9 2.2 2.0 -0.2 3.0 2.0 2.0 1.7
Alcohol intake frequency. 1.0 2.3 14.4 -1.7 -0.2 1.5 -1.0 -1.4 -1.6 0.0 -1.4 -1.6 -0.3 -1.0 0.0 -0.4 3.8 -1.1 -1.9 -1.5 -1.7 -1.5 -1.8 -0.2 -1.9 -1.4 -2.7 -0.9 -0.7 0.2 -1.6
Comparative height size at age 10 0.3 1.4 4.5 -0.8 -0.8 1.1 -1.1 -1.2 -1.1 -0.5 -1.2 -1.3 -1.4 -0.9 0.3 -1.0 1.8 -1.3 -1.3 -2.1 -1.1 -1.3 -1.5 -0.9 -1.3 -1.0 -0.5 -1.5 -0.9 -0.8 -1.4
Number of full sisters 1.2 1.4 7.4 -0.9 -0.7 -0.9 -1.7 -1.6 -1.3 -1.2 -1.4 -1.3 -0.4 -1.7 1.0 0.7 2.7 -1.0 -1.1 -0.2 -0.0 -1.7 -1.1 -0.1 -1.1 -0.4 -1.0 -1.2 -1.3 -1.0 -0.6
Suffer from ‘nerves’ 1.8 2.8 8.6 1.0 2.0 -0.3 1.4 1.6 1.8 1.6 1.8 1.6 1.6 1.4 -1.7 -0.2 -2.9 0.7 2.1 2.4 0.8 2.3 1.6 0.9 1.7 2.0 2.6 1.0 1.6 1.3 1.8
Overall health rating 1.5 3.2 10.9 -1.7 -0.1 0.0 -1.8 -2.1 -1.4 -1.2 -2.0 -2.3 -1.1 -1.4 0.9 1.1 2.6 -2.8 -1.7 -1.4 -0.2 -1.3 -2.2 -1.1 -2.2 -1.9 -3.3 -2.2 -2.5 -1.0 -1.7
Chest pain or discomfort 0.8 1.2 4.7 -0.2 2.2 -1.3 0.7 0.7 1.2 0.9 1.0 0.7 1.5 0.7 -1.2 -1.3 0.2 -0.6 1.6 1.2 1.1 1.1 1.0 1.3 1.0 1.3 0.3 0.0 -0.3 0.9 1.4
Had major operations 0.5 0.6 2.7 -0.7 -0.1 1.5 -0.1 -0.5 0.1 -0.1 -0.6 -0.5 -0.7 0.2 0.4 -0.5 0.1 -0.5 -0.3 -0.9 -1.6 -0.5 -0.7 -0.2 -0.9 -1.6 -0.9 0.2 0.5 0.2 -1.5
Age at last live birth 2.3 3.4 9.1 2.3 0.1 -1.1 1.6 2.5 2.0 1.0 1.9 2.4 1.6 1.1 -0.7 0.0 -1.4 1.8 1.1 3.0 1.2 1.9 2.2 1.0 2.5 2.6 2.4 2.2 1.7 1.3 2.3
Family relationship satisfaction 1.3 1.6 9.7 -0.1 0.9 -3.1 -0.4 -0.6 -0.7 0.0 0.2 -0.1 1.0 -0.9 -0.6 -0.2 1.1 -0.8 0.3 1.3 2.9 0.2 0.1 0.3 0.5 1.6 2.3 -1.4 -1.8 -0.7 2.0
Leg pain on walking 0.2 0.3 1.7 -0.6 0.2 -0.4 -0.3 -0.7 -0.5 -0.1 -0.5 -0.8 0.0 -0.3 -0.2 -0.1 -0.6 0.0 -0.7 0.0 0.8 0.1 -0.7 -0.4 -0.7 0.2 0.3 -1.0 -1.3 -0.3 0.1
Qualifications: NVQ or HND or HNC or equivalent 4.1 5.0 9.9 -1.0 -2.8 -0.1 -3.1 -3.1 -2.9 -2.4 -2.7 -2.4 -2.5 -2.8 2.1 2.6 1.8 -0.9 -0.8 -1.2 -0.8 -3.1 -2.4 -2.0 -2.1 -1.6 -0.7 -2.8 -2.1 -3.0 -2.0
Commuting to job workplace: Car/motor vehicle 1.1 1.2 6.3 0.3 -2.5 -1.7 -1.1 -0.7 -1.8 -1.2 -1.2 -0.7 -0.4 -1.5 1.2 1.9 0.5 -0.4 -1.6 -0.5 0.1 -1.3 -0.5 -0.5 -0.6 0.1 0.4 -0.8 -1.0 -1.3 -0.2
Illness, injury, bereavement, stress in last 2 years 4.0 4.9 10.0 1.3 1.4 -1.5 2.7 2.4 2.5 2.0 2.8 2.7 2.3 2.2 -1.8 -1.3 -1.7 1.5 2.1 2.8 1.7 2.4 2.6 2.0 2.7 2.3 3.2 2.2 2.0 1.8 2.7
Medication: Aspirin 0.4 0.6 4.8 -0.9 2.2 0.5 0.3 -0.4 -0.1 0.7 0.1 -0.4 0.2 0.3 -0.8 -1.7 0.3 -1.0 0.2 -0.9 -0.1 0.3 -0.3 0.3 -0.4 -0.5 -1.2 -0.6 -0.4 0.6 -0.2
Supplements: Vitamin C 0.4 0.5 5.3 -2.3 0.2 -0.4 -0.5 -0.8 -0.7 -0.1 -0.3 -0.7 -0.6 -0.7 -0.2 -0.6 -0.3 0.3 -0.4 -0.4 0.2 -0.4 -0.7 -0.6 -0.5 -0.4 0.6 -1.3 -1.0 -0.3 -0.1
Knee pain experienced in last month 0.1 0.2 1.0 0.6 0.4 -1.0 -0.5 -0.2 0.4 -0.1 -0.1 -0.3 0.5 -0.2 -0.1 -0.1 0.7 -0.4 -0.5 -0.5 0.6 0.1 0.0 0.4 -0.1 0.5 -0.5 -0.4 -0.5 0.3 0.1
Hypertension (Self-reported) 1.1 3.1 6.9 0.4 2.6 -1.2 1.8 1.6 2.0 1.4 2.3 1.8 2.4 1.7 -1.5 -2.4 0.4 -0.2 1.3 1.0 2.0 2.2 2.1 2.1 2.1 1.9 0.6 1.4 0.8 2.0 2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.0 0.2 0.8 0.7 0.8 0.4 1.0 0.3 0.6 0.5 0.4 0.8 -0.2 -0.5 -0.6 0.6 0.8 -0.4 0.1 0.6 0.6 0.6 0.5 0.4 -1.0 0.8 0.4 0.8 0.3
Illnesses of father: Heart disease 0.9 1.2 3.3 -1.6 0.9 0.3 -1.0 -1.4 -0.9 0.3 -1.1 -1.5 -0.1 -0.6 -0.6 -1.2 1.3 -1.4 -1.0 -1.2 -0.6 -0.2 -1.5 -0.8 -1.5 -0.8 -1.8 -1.6 -1.1 -0.1 -1.0
Illnesses of siblings: Diabetes 2.5 3.1 5.3 -1.1 -0.6 0.8 -2.3 -1.5 -2.2 -1.6 -2.1 -2.2 -2.2 -2.0 1.5 2.1 0.7 -0.7 -1.8 -0.9 -0.7 -1.8 -2.2 -2.3 -2.2 -2.0 -1.4 -2.1 -1.5 -1.8 -2.0
Smoking status: Previous 1.2 1.9 3.7 -0.3 -1.7 -1.0 -1.7 -1.2 -1.8 -1.9 -1.6 -1.4 -1.3 -1.6 1.8 1.7 -0.6 -1.2 -1.5 -0.3 0.2 -1.4 -1.0 -1.6 -1.1 -1.0 -0.5 -1.3 -1.9 -1.9 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.5 4.5 -1.1 -0.6 -1.2 -0.0 0.3 -0.3 0.1 0.1 0.1 0.5 -0.6 -0.3 -0.0 2.1 -0.4 0.4 0.6 1.0 -0.5 -0.0 0.6 0.4 0.7 0.7 -0.5 -0.7 -0.2 1.0
Whole body fat-free mass 0.3 1.9 7.6 -0.5 -2.4 -1.8 -1.7 -1.8 -1.4 -1.7 -1.5 -1.2 -0.2 -1.8 1.5 0.5 2.8 -0.4 -1.4 -1.4 0.8 -2.2 -0.8 0.2 -0.9 0.1 -0.2 -1.0 -1.8 -1.3 -0.1
Leg fat-free mass (right) 0.3 1.8 5.8 -0.7 -2.0 -2.0 -1.7 -1.8 -1.0 -1.7 -1.4 -1.2 0.1 -1.8 1.4 0.3 2.4 -0.4 -1.4 -1.1 1.4 -1.9 -0.8 0.2 -0.9 0.2 -0.4 -1.1 -2.0 -1.3 0.1
Arm fat percentage (left) 0.1 0.4 2.1 1.1 -1.0 -0.7 -0.6 0.3 0.7 -0.9 -0.2 -0.1 0.6 -0.2 0.9 1.4 0.6 0.9 -0.3 0.5 0.8 -0.4 0.2 0.6 0.1 0.4 -0.9 0.5 -0.4 0.0 0.2
Average weekly red wine intake 3.0 4.5 16.0 -1.8 2.1 -0.5 2.1 2.1 1.9 2.2 2.3 1.8 2.1 1.8 -2.5 -1.1 -4.0 1.3 2.4 3.1 2.0 3.1 1.8 0.5 2.0 2.3 2.9 0.9 1.0 1.5 2.4
Handedness (chirality/laterality): Left-handed 0.3 0.4 2.4 -1.4 -0.5 0.5 0.3 0.4 0.1 0.6 0.7 0.7 0.3 0.5 -0.6 0.3 1.6 0.3 0.8 0.0 0.1 0.0 0.3 0.7 0.7 0.3 0.2 0.4 0.5 0.5 0.5
Mood swings 0.2 0.4 3.6 -0.8 1.9 0.4 0.1 0.1 0.5 0.4 -0.1 -0.3 0.0 0.4 -0.5 -0.7 -0.9 -1.3 0.4 0.2 -0.3 0.5 -0.4 -0.3 -0.4 -0.4 -0.9 -0.4 -0.0 0.3 -0.4
Loneliness, isolation 0.5 0.6 2.6 0.1 0.6 -1.6 0.5 0.1 0.1 1.1 0.5 0.2 1.3 0.4 -1.4 -0.3 0.7 0.1 1.6 0.4 0.6 0.6 0.4 1.4 0.4 0.8 1.0 -0.7 -0.1 0.6 0.9
Long-standing illness, disability or infirmity 0.5 0.7 3.6 -1.1 0.7 -0.1 -0.7 -0.8 -0.5 -0.1 -0.7 -1.0 0.2 -0.6 -0.2 -0.8 1.9 -0.3 -0.7 -0.6 0.5 -0.4 -0.8 -0.1 -0.9 -0.4 -1.8 -1.0 -1.7 -0.1 -0.2
Ever had bowel cancer screening 1.3 1.6 7.6 1.2 -1.3 2.1 -0.3 -0.6 -0.9 0.1 -0.7 -0.4 -0.2 0.3 0.1 -0.1 0.7 2.4 -0.0 -2.8 -2.6 -0.7 -0.5 0.5 -0.7 -2.2 -1.9 0.1 0.3 0.3 -1.8
Diabetes diagnosed by doctor 0.3 0.5 1.7 -1.0 1.3 0.3 0.2 -0.3 0.3 0.8 0.1 -0.4 0.5 0.7 -0.9 -0.9 0.4 -0.3 0.6 -1.0 -0.6 0.7 -0.4 0.5 -0.4 -1.1 -1.0 -0.4 -0.0 0.8 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 2.6 -1.6 -0.4 -0.3 0.1 0.4 -0.3 0.1 0.1 0.2 -0.3 -0.4 -0.0 0.2 1.6 -0.7 0.2 0.5 0.6 -0.5 0.2 0.0 0.2 -0.0 -0.2 -0.1 -0.1 -0.2 0.3
Friendships satisfaction 1.7 2.1 13.9 -0.6 0.7 -3.7 -0.5 -0.7 -0.7 0.5 0.3 -0.1 1.7 -1.0 -1.2 -0.3 1.3 -1.3 0.2 1.9 3.1 0.5 0.2 0.6 0.6 2.1 1.8 -1.5 -2.0 -0.1 2.3
Qualifications: nursing, teaching 1.1 1.6 4.9 1.2 1.7 -1.1 0.6 0.7 1.4 1.1 1.4 0.8 1.8 1.0 -1.4 -2.2 -1.5 0.7 0.8 1.1 1.9 2.0 1.0 0.5 1.1 1.9 1.1 0.4 0.0 1.0 1.6
Commuting to job workplace: Walk 0.6 0.6 1.7 -1.1 1.1 0.6 0.9 0.2 0.8 1.0 0.9 0.7 0.6 1.0 -1.0 -0.9 1.1 -0.2 0.9 -0.6 -0.3 0.5 0.5 1.3 0.6 0.2 0.4 0.4 0.9 1.0 0.2
Eye problems/disorders: Cataract 0.3 0.4 4.5 0.5 2.1 0.2 0.2 0.2 0.4 0.5 0.6 0.2 0.1 0.1 -0.5 -0.9 -1.4 -0.2 -0.2 0.1 0.3 0.6 0.2 -0.3 0.2 0.1 0.5 0.1 0.5 0.4 0.2
Mouth/teeth dental problems: Mouth ulcers 0.1 0.1 0.5 0.7 0.3 -0.3 0.2 0.1 0.4 -0.3 0.2 0.2 0.2 0.4 0.3 -0.0 0.4 -0.6 -0.1 -0.0 0.6 0.3 0.3 0.2 0.4 0.6 -0.5 0.2 -0.2 0.1 0.3
Medication for cholesterol 1.2 1.9 4.1 -0.9 -1.9 0.4 -1.4 -1.0 -1.0 -0.6 -1.8 -1.4 -1.2 -1.4 0.7 0.9 2.0 -0.3 -1.9 -1.2 -2.0 -2.0 -1.5 -0.9 -1.5 -1.7 -2.0 -1.0 -0.7 -0.7 -1.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.7 0.8 2.5 -0.1 0.4 -0.1 -0.9 -1.1 -0.5 -0.3 -1.1 -1.1 -0.8 -0.8 0.1 -0.1 -1.6 -1.5 -0.8 -0.7 -0.6 -0.2 -1.0 -1.4 -1.0 -1.2 -0.6 -1.5 -1.1 -0.9 -1.1
Back pain experienced in last month 1.6 2.4 8.2 -1.8 0.1 0.5 -1.7 -2.4 -1.6 -1.1 -1.7 -2.0 -1.5 -1.6 0.7 -0.3 0.3 -2.9 -1.2 -0.9 -0.1 -1.1 -2.0 -1.8 -1.8 -1.2 -0.9 -2.4 -2.1 -1.7 -1.2
Mineral and other dietary supplements 0.1 0.2 1.2 -0.6 1.1 0.2 0.0 0.0 0.7 -0.3 0.3 0.1 -0.3 0.0 0.2 -0.8 0.0 -0.9 0.5 0.2 0.5 0.1 0.0 -0.1 0.2 -0.3 -0.1 0.1 -0.3 0.0 0.2
Breast cancer (self-reported) 0.3 0.4 1.3 0.8 -0.7 -0.7 0.5 0.7 0.6 0.1 0.6 0.8 0.1 0.1 0.0 0.1 -0.3 0.6 0.3 0.9 0.5 0.3 0.7 0.1 0.9 1.0 1.2 0.7 0.4 0.2 0.8
Asthma (self-reported) 0.3 0.6 1.5 -0.3 -0.9 -0.6 -1.2 -0.5 -0.6 -0.7 -0.8 -1.1 -0.2 -1.0 0.4 1.1 0.9 0.4 -0.4 0.8 0.7 -0.5 -0.9 -0.7 -0.9 -0.4 -0.4 -1.2 -1.2 -0.8 -0.4
Osteoporosis (self-reported) 0.3 0.4 2.6 0.5 0.6 0.1 0.7 0.5 0.3 0.6 0.5 0.5 0.1 0.3 -0.5 -1.6 -1.2 0.4 -0.3 0.7 0.2 0.8 0.3 -0.4 0.4 0.4 1.2 0.6 0.4 0.3 0.5
Osteoarthritis (self-reported) 0.2 0.2 1.5 0.7 0.1 -0.5 -0.5 -0.5 -0.1 -0.1 -0.4 -0.5 1.2 -0.6 -0.1 0.1 0.3 -0.4 -0.5 0.1 0.8 0.1 -0.0 0.3 -0.4 0.2 -0.5 -0.3 -0.9 -0.1 0.4
Medication: Aspirin 0.4 0.5 3.2 -0.4 1.8 -0.6 0.3 -0.3 -0.0 0.6 0.3 -0.2 0.6 0.3 -0.8 -1.4 0.0 -1.6 0.1 -0.6 0.6 0.5 -0.0 0.4 -0.1 -0.1 -0.7 -0.6 -0.8 0.5 0.2
Medication: Gliclazide 0.5 0.6 1.9 -0.2 0.6 0.8 0.8 0.2 0.3 1.4 0.5 0.0 0.6 0.8 -1.4 -1.3 1.3 0.7 0.4 -1.0 -1.0 0.6 -0.1 0.7 -0.2 -0.8 -0.3 0.0 0.5 1.2 -0.2
Illnesses of father: None of the above (group 1) 0.4 0.5 3.0 0.5 -1.7 0.7 -0.2 -0.3 0.2 -0.1 -0.5 -0.2 -0.2 -0.1 0.2 1.7 -0.5 0.9 0.5 -0.6 -1.5 -0.8 -0.3 0.2 -0.3 -0.3 0.2 -0.1 0.4 -0.4 -0.7
Smoking status: Current 2.4 3.8 13.2 -1.4 -0.7 3.4 -1.3 -1.8 -1.3 -0.8 -1.9 -1.7 -2.8 -0.8 0.9 0.6 1.8 -0.2 -0.7 -3.6 -3.2 -2.3 -2.2 -1.1 -2.1 -3.1 -1.9 -1.4 -0.4 -1.1 -2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.5 7.5 1.0 -0.6 -0.7 1.1 1.4 0.8 0.5 1.2 1.6 0.9 0.8 -0.4 1.2 -0.0 2.7 1.5 1.3 0.2 0.5 1.5 1.6 1.7 1.4 1.5 1.5 1.3 0.9 1.3
Whole body water mass 0.3 1.9 6.9 -0.5 -2.3 -1.8 -1.7 -1.9 -1.3 -1.7 -1.5 -1.2 -0.1 -1.8 1.4 0.5 2.6 -0.4 -1.4 -1.4 0.9 -2.1 -0.9 0.2 -0.9 0.1 -0.3 -1.1 -1.8 -1.3 -0.1
Leg predicted mass (right) 0.3 1.7 5.6 -0.6 -2.0 -2.0 -1.6 -1.8 -1.0 -1.7 -1.4 -1.2 0.1 -1.8 1.4 0.3 2.4 -0.4 -1.4 -1.1 1.4 -1.9 -0.8 0.2 -0.8 0.3 -0.4 -1.1 -2.0 -1.2 0.2
Arm fat mass (left) 0.2 0.7 2.5 1.0 -1.6 -1.1 -1.0 -0.2 0.1 -1.3 -0.7 -0.5 0.5 -0.7 1.2 1.3 1.6 0.8 -0.6 -0.1 0.7 -1.1 -0.1 0.7 -0.3 0.2 -1.1 0.1 -0.8 -0.3 0.1
Number of self-reported non-cancer illnesses 0.6 1.0 5.8 0.1 2.4 -0.1 1.1 1.0 1.3 0.8 1.1 0.4 1.0 0.9 -0.9 -1.3 0.3 0.6 0.6 0.9 1.7 1.5 0.6 0.5 0.5 0.7 -0.2 0.4 -0.1 1.1 1.1
Average weekly champagne plus white wine intake 0.3 0.4 3.1 1.2 -1.8 -0.1 0.2 0.3 -0.1 -0.4 -0.1 0.3 -0.3 0.1 0.5 1.4 -1.1 1.2 -0.1 -0.3 -0.5 -0.1 0.3 -0.0 0.2 0.1 -0.1 0.5 0.1 -0.4 -0.0
Miserableness 0.4 0.7 2.7 -1.4 1.3 -0.9 0.5 0.2 0.0 1.2 0.3 0.0 1.1 0.6 -1.5 -0.6 0.3 -0.2 1.7 0.5 0.4 0.7 0.2 1.0 0.2 0.8 1.1 -0.8 -0.4 0.6 0.9
Guilty feelings 0.9 1.4 4.2 0.3 1.9 -1.1 0.8 0.5 0.3 1.7 1.0 0.7 1.4 0.6 -2.0 -1.2 -1.7 -0.1 1.5 1.2 0.6 1.6 0.8 0.9 0.9 1.0 2.1 -0.5 0.3 0.9 1.3
Wears glasses or contact lenses 0.6 0.7 3.7 1.4 1.3 1.1 -0.9 -0.8 0.3 -0.5 -0.7 -0.6 -0.5 -0.3 0.4 0.2 -1.9 1.4 0.4 -0.0 -1.1 -0.1 -0.5 -0.8 -0.7 -0.9 -0.9 -0.3 0.1 -0.5 -1.3
Ever taken oral contraceptive pill 1.0 1.1 4.0 -1.3 -0.3 -2.0 0.4 0.8 -0.1 0.8 0.9 0.7 1.1 0.3 -1.1 1.2 -0.2 -0.8 1.7 1.7 2.0 0.7 0.7 0.7 1.0 1.4 1.5 -0.6 -0.4 0.0 1.6
Hearing aid user 0.9 1.0 9.0 0.1 0.6 -3.0 -0.6 -0.2 -0.5 -0.3 0.1 -0.3 1.1 -0.8 -0.1 -0.1 -0.3 -1.7 -0.0 0.7 2.4 0.1 0.2 0.3 0.2 1.2 0.6 -1.0 -1.6 -0.4 1.1
Mother’s age at death 0.2 0.2 1.1 0.4 -0.2 -0.8 0.2 0.7 0.4 -0.4 0.2 0.2 0.3 0.0 0.6 1.1 -1.0 -0.3 0.1 0.7 0.6 0.3 0.4 -0.1 0.2 0.0 0.2 0.7 0.2 -0.1 0.3
Financial situation satisfaction 0.4 0.4 1.4 -0.3 0.1 -0.9 -0.3 -0.5 -1.1 -0.2 -0.4 -0.5 -0.4 -0.6 -0.0 0.2 0.9 -0.7 0.5 0.3 1.0 -0.7 -0.6 -0.1 -0.2 0.5 1.2 -1.1 -1.2 -0.8 0.6
Tinnitus: Yes, now most or all of the time 1.2 1.4 4.2 -0.9 -0.8 -0.7 -1.4 -1.0 -1.5 -1.0 -1.3 -1.5 -0.3 -1.6 0.8 1.1 2.1 -0.3 -1.6 -0.2 0.5 -1.4 -1.4 -0.5 -1.3 -0.7 -1.4 -1.4 -1.7 -0.8 -0.6
Commuting to job workplace: Public transport 0.5 0.6 2.2 0.1 1.5 0.6 -0.0 -0.2 -0.1 -1.0 -0.3 -0.7 -1.3 -0.3 0.9 -1.0 -1.3 -0.8 -0.1 0.7 1.2 -0.2 -0.7 -1.4 -0.6 -0.9 -0.3 -0.4 -1.1 -0.9 -0.1
Eye problems/disorders: Glaucoma 0.3 0.4 1.7 -1.3 0.8 0.1 0.7 0.4 -0.3 1.3 0.3 0.1 1.1 0.8 -1.2 -0.7 0.5 0.0 0.6 -0.4 -0.3 0.8 0.2 0.6 -0.1 -0.3 -0.3 -0.1 0.2 0.9 0.3
Medication: Blood pressure 0.9 1.8 7.5 -0.5 2.3 -1.9 0.8 0.8 1.4 0.4 1.5 0.9 1.3 0.6 -0.7 -2.0 -1.3 -0.7 1.0 1.2 2.7 1.8 1.3 0.6 1.3 1.7 1.4 0.2 -0.4 0.5 1.9
Pain type(s) experienced in last month: Hip pain 0.9 1.1 4.6 -0.3 -1.5 -1.0 -1.9 -2.1 -0.9 -1.1 -1.3 -1.1 0.0 -1.8 0.8 0.6 0.0 -1.4 -0.8 -0.9 0.1 -1.3 -0.8 -0.4 -0.7 -0.0 0.2 -1.4 -1.1 -1.3 -0.4
Supplements: Fish oil (including cod liver oil) 0.3 0.3 2.0 -0.4 -1.2 -0.4 0.4 0.2 -0.7 0.6 -0.1 0.0 0.9 0.1 -0.5 1.0 -0.0 1.4 -0.0 0.9 0.3 0.1 0.2 0.3 -0.0 1.0 0.6 -0.0 -0.1 -0.1 0.6
High cholesterol (Self-reported) 2.1 3.8 7.3 0.8 2.6 -1.8 2.1 1.8 2.2 1.7 2.4 1.9 2.4 1.9 -1.7 -2.3 -0.8 -0.4 1.8 2.4 2.5 2.7 2.2 1.4 2.1 2.0 1.4 1.6 0.6 1.8 2.5
Medication: Bendroflumethiazide 0.4 0.6 2.3 1.0 0.3 -1.5 0.2 0.3 0.6 0.3 0.8 0.8 1.3 0.2 -0.5 -0.6 -0.1 0.3 0.8 0.1 0.9 0.6 1.0 1.3 1.1 1.1 1.1 0.2 0.3 0.5 1.0
Medication: Paracetamol 1.2 1.9 3.9 0.2 -0.9 -0.7 -1.1 -1.8 -1.4 -1.7 -1.6 -1.5 -1.4 -1.2 1.7 0.9 -0.0 -1.1 -1.6 -1.7 -0.5 -1.5 -1.2 -1.2 -1.5 -1.5 -1.9 -1.3 -2.0 -1.4 -1.3
Medication: Lisinopril 3.6 4.6 10.9 3.0 1.5 -2.8 2.0 2.1 1.8 0.7 2.3 2.2 2.5 1.4 -0.7 -0.8 -2.7 0.2 1.9 2.9 3.3 2.2 2.8 1.5 2.6 2.5 2.7 1.5 0.1 1.1 3.2
Medication: Atorvastatin 1.3 1.6 6.0 -0.6 2.5 -1.6 1.1 1.3 1.1 1.5 1.4 0.8 1.8 0.7 -1.6 -1.7 0.3 0.7 0.7 1.6 1.5 1.7 1.2 1.0 0.9 0.7 0.5 0.4 -0.0 1.6 1.5
Illnesses of father: High blood pressure 1.2 1.5 3.2 1.2 1.1 -0.7 1.4 1.6 0.9 1.2 1.4 1.3 1.8 1.4 -1.1 -1.2 0.1 0.5 1.4 1.0 0.7 1.6 1.4 1.6 1.3 1.1 0.2 1.2 0.9 1.5 1.2
Alcohol drinker status: Never 0.8 0.9 6.5 -1.1 0.3 -0.0 0.7 0.4 0.1 1.0 1.0 0.8 1.0 0.4 -1.0 0.6 1.7 2.5 -0.0 1.8 0.8 0.7 0.7 0.7 0.8 0.9 0.5 0.7 0.3 1.1 1.1
Ever smoked 2.1 3.7 7.2 -1.1 -2.0 1.2 -1.9 -2.1 -1.9 -2.2 -2.2 -1.9 -2.7 -1.7 2.1 1.9 0.6 -1.3 -1.6 -2.6 -1.1 -2.5 -2.0 -1.6 -1.9 -2.4 -1.8 -1.7 -1.8 -2.2 -2.1
Basal metabolic rate 0.3 1.6 7.2 -0.4 -2.3 -1.8 -1.6 -1.6 -1.2 -1.5 -1.3 -1.0 0.0 -1.6 1.3 0.6 2.7 -0.1 -1.2 -1.2 0.8 -2.0 -0.7 0.4 -0.7 0.2 -0.2 -0.9 -1.6 -1.1 0.0
Leg fat percentage (left) 0.1 0.5 3.5 1.9 -0.8 -0.6 -0.1 0.8 0.2 -0.4 0.0 0.3 0.8 0.2 0.5 1.5 0.7 0.9 0.0 0.5 0.1 -0.1 0.5 0.9 0.3 0.4 -0.5 0.9 0.2 0.4 0.2
Arm fat-free mass (left) 0.3 1.5 6.0 0.1 -2.3 -1.7 -1.4 -1.5 -1.3 -1.6 -1.4 -1.0 -0.1 -1.6 1.4 0.6 2.4 -0.3 -1.2 -1.3 0.5 -1.9 -0.7 0.2 -0.8 -0.1 -0.4 -0.8 -1.5 -1.1 -0.2
Number of operations (self-reported) 0.2 0.3 1.0 0.7 -0.6 0.7 -0.2 -0.5 -0.3 -0.1 -0.7 -0.4 -0.2 -0.3 0.4 0.6 -0.8 0.0 -0.4 -0.2 -1.0 -0.5 -0.2 -0.2 -0.7 -0.7 -0.5 0.3 0.6 -0.2 -0.8
Average weekly beer plus cider intake 2.5 3.7 11.2 -1.6 -2.4 -0.6 -2.3 -2.0 -2.9 -2.4 -2.3 -1.6 -1.5 -2.3 2.4 2.3 2.7 -2.3 -1.1 -0.9 -0.4 -3.3 -1.6 -0.3 -1.4 -1.2 -0.5 -1.6 -1.7 -2.3 -1.1
Irritability 2.2 3.7 9.5 -0.9 2.9 -0.2 2.2 1.7 2.0 2.9 2.3 1.6 2.4 2.5 -3.1 -2.7 -1.3 -0.3 2.7 0.2 0.3 2.9 1.8 1.8 1.6 0.8 0.8 0.7 1.0 2.6 1.4
Risk taking 0.7 1.0 8.1 -0.3 -0.5 1.3 0.0 -0.6 -0.6 -0.1 -0.5 -0.3 -1.0 0.4 0.3 0.0 1.7 0.6 -0.3 -2.8 -2.1 -1.1 -0.5 0.4 -0.6 -1.6 -1.0 -0.2 0.5 0.0 -1.5
Ever had prostate specific antigen (PSA) test 0.5 0.6 3.2 1.4 0.7 -0.5 0.7 0.6 -0.0 0.9 0.6 0.7 0.9 0.7 -0.7 0.2 -0.6 1.8 0.9 0.2 -0.4 0.6 0.6 0.9 0.6 0.4 0.9 0.4 1.0 0.6 0.5
Fractured/broken bones in last 5 years 0.7 1.0 4.4 0.7 1.2 1.6 -0.4 -0.2 0.4 0.2 -0.4 -0.6 -0.9 0.1 -0.1 -0.6 -1.7 -0.1 -0.6 -1.1 -2.1 0.4 -0.7 -0.9 -0.9 -1.8 -0.9 -0.2 1.1 0.3 -2.0
Age started oral contraceptive pill 1.1 1.3 4.4 0.7 -0.6 -0.7 0.8 1.3 1.8 -0.1 1.2 1.3 1.1 0.8 0.1 0.0 -0.9 0.7 0.9 2.1 1.5 1.4 1.6 0.6 1.4 1.8 0.1 1.9 0.6 0.7 1.3
Diastolic blood pressure, automated reading 0.8 2.6 11.2 -0.4 3.3 1.0 1.8 1.4 1.7 2.3 1.7 0.9 1.3 2.3 -2.4 -3.3 -0.6 -0.9 1.2 0.6 0.0 2.6 0.8 0.6 0.7 0.5 -0.4 0.8 1.3 2.3 0.7
Ever depressed for a whole week 1.3 1.6 6.2 -0.6 0.3 0.5 -1.2 -1.1 -1.3 0.2 -1.6 -1.8 -0.8 -1.0 -0.5 -1.0 0.7 -2.5 -0.8 -0.9 -0.9 -0.6 -1.9 -1.6 -1.9 -1.3 -1.2 -2.1 -1.3 -0.6 -1.2
Unable to work because of sickness or disability 1.7 2.2 7.3 -1.1 -1.0 -1.1 -1.2 -1.5 -2.3 -1.0 -1.7 -1.8 -0.8 -1.2 0.9 1.6 2.7 -1.2 -1.0 -1.1 -0.6 -1.7 -1.4 -0.1 -1.7 -1.7 -2.1 -1.8 -2.2 -1.1 -1.0
Commuting to job workplace: Cycle 0.4 0.5 6.2 0.3 0.2 0.3 0.7 0.2 0.8 0.5 0.4 0.5 0.1 0.7 -0.4 0.2 -1.4 2.5 0.6 -0.2 -0.4 0.4 0.4 0.3 0.5 -0.1 1.2 0.6 0.7 0.1 0.1
Myopia 1.0 1.5 5.0 0.1 0.3 -1.1 0.9 1.0 0.8 0.9 1.5 1.2 1.7 0.8 -1.0 -0.6 -0.1 0.7 1.1 2.1 1.8 1.5 1.3 0.9 1.5 2.2 1.1 0.9 0.1 1.1 1.7
Vascular/heart problems diagnosed by doctor 1.2 3.3 10.0 -0.2 -3.1 1.0 -1.7 -1.4 -1.8 -1.7 -2.4 -1.8 -2.4 -1.6 1.8 3.2 -0.7 0.6 -1.5 -0.8 -2.0 -2.1 -2.1 -2.2 -2.1 -1.9 -0.6 -1.2 -0.9 -2.1 -2.2
Cholesterol lowering medication 1.4 2.0 4.3 0.8 1.9 -0.6 1.6 1.6 1.7 0.7 1.9 1.4 1.0 1.5 -0.7 -1.2 -1.8 0.5 1.6 1.8 2.1 2.1 1.5 0.6 1.4 1.4 1.5 1.3 0.6 1.1 1.7
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 1.8 -0.6 1.2 0.8 0.3 0.1 0.5 0.4 0.2 -0.1 0.5 0.7 -0.4 0.1 -0.3 -0.0 0.8 -0.4 -0.4 0.6 0.0 0.3 -0.1 -0.2 -1.4 -0.0 -0.2 0.6 -0.2
Pain experienced in last month 2.7 4.6 10.7 0.8 1.4 -0.6 2.7 3.3 1.4 1.6 2.7 2.7 2.0 2.3 -1.3 -0.2 -1.4 1.8 2.2 2.9 1.3 2.3 2.8 1.9 2.5 2.1 2.4 2.8 2.3 2.0 2.4
Supplements: Calcium 0.3 0.3 1.8 0.6 0.8 -0.7 0.7 0.2 0.1 0.1 0.5 0.2 0.6 0.4 -0.1 -1.0 -0.3 0.6 -0.2 0.4 1.4 0.7 0.2 0.0 0.2 0.3 0.0 0.3 -0.5 0.2 0.7
Basal cell carcinoma (self-reported) 1.2 1.4 8.0 1.9 0.3 0.8 1.2 1.2 1.8 0.6 1.2 1.5 0.5 1.2 -0.3 -0.5 -0.2 2.8 1.1 0.8 -0.1 0.9 1.2 0.9 1.4 0.7 1.1 1.9 1.6 1.0 0.6
Heart attack/myocardial infarction (self-reported) 0.4 0.5 3.9 -0.9 1.2 0.3 -0.2 -0.6 -0.7 0.4 -0.3 -0.5 0.2 -0.3 -0.4 -2.0 1.0 -0.9 -0.4 -0.8 -0.5 -0.7 -0.5 0.3 -0.7 -0.6 -0.5 -0.6 -0.2 0.2 -0.4
Deep venous thrombosis (DVT) (self-reported) 0.5 0.7 9.1 -1.1 0.4 0.2 -0.4 -0.8 -0.7 0.3 -0.6 -0.7 -0.1 -0.3 -0.5 -0.3 3.0 0.6 0.1 -0.6 -0.1 -0.9 -0.8 0.6 -0.7 0.2 -0.8 -1.0 -0.7 -0.0 -0.3
Heart disease (siblings) 1.2 1.5 3.7 -0.0 -0.9 0.7 -1.9 -1.1 -1.8 -0.6 -1.5 -1.4 -1.2 -1.7 0.5 0.3 0.6 -1.5 -1.0 -1.3 -1.3 -1.5 -1.4 -1.3 -1.3 -1.3 -0.2 -1.7 -0.8 -1.1 -1.3
Alcohol drinker status: Previous 0.3 0.4 1.7 -0.4 0.2 0.3 -0.2 0.2 -0.8 -0.4 -0.7 -0.8 -0.5 -0.5 0.5 -0.2 0.6 -0.9 -0.4 0.9 0.0 -0.5 -0.7 -0.9 -0.9 -0.5 -1.3 -0.5 -1.0 -0.4 -0.3
Pack years of smoking 0.6 0.9 3.7 0.4 0.9 0.6 -0.9 -0.7 0.0 -0.8 -0.9 -1.0 -1.2 -0.6 0.8 -0.6 -1.4 -0.5 -0.7 -1.1 -1.0 -0.5 -1.0 -1.3 -1.2 -1.9 -1.1 -0.7 -0.3 -0.5 -1.4
Impedance of whole body 0.4 1.9 4.9 -1.1 2.0 1.8 1.5 1.7 1.2 2.2 1.7 1.3 -0.1 1.6 -2.2 -1.6 -1.3 -0.2 2.0 1.0 -0.6 1.9 0.7 -0.0 1.3 0.3 1.4 0.2 1.5 1.3 0.5
Leg fat mass (left) 0.1 0.4 2.2 1.5 -1.2 -0.7 -0.4 0.3 0.2 -0.7 -0.3 -0.0 0.7 -0.1 0.7 0.9 1.3 0.9 -0.2 -0.1 0.1 -0.6 0.2 0.9 0.0 0.2 -0.9 0.6 -0.1 0.2 0.0
Arm predicted mass (left) 0.3 1.5 6.4 0.2 -2.2 -1.6 -1.4 -1.6 -1.3 -1.5 -1.4 -1.1 -0.1 -1.5 1.3 0.6 2.5 -0.4 -1.1 -1.5 0.4 -2.0 -0.8 0.3 -0.8 -0.1 -0.5 -0.8 -1.5 -1.1 -0.3