[Hub]/) : Traits : Cardiovascular Disease : ← →

chr4:17,104,059-18,507,692

Best TWAS P=8.78e-12 · Best GWAS P=3.12e-10 conditioned to 0.00256

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 5.9 -6.8 1.3e-11 -0.69 0.05 0.77 FALSE
2 GTEx Artery Tibial DCAF16 0.16 0.16 lasso 5 0.13 1.5e-10 -5.0 -5.4 6.1e-08 -0.31 0.94 0.06 FALSE
3 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 -4.4 -5.7 1.5e-08 -0.45 0.10 0.76 FALSE
4 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 6.0 -6.7 2.0e-11 -0.69 0.03 0.67 FALSE
5 GTEx Nerve Tibial DCAF16 0.16 0.14 lasso 3 0.14 2.8e-10 -4.7 -5.2 2.2e-07 -0.32 0.97 0.03 FALSE
6 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 -4.7 -6.2 5.3e-10 -0.66 0.05 0.59 FALSE
7 GTEx Stomach DCAF16 0.21 0.04 lasso 6 0.02 5.6e-02 -4.9 -5.3 1.5e-07 -0.23 0.19 0.06 FALSE
8 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 -4.7 -5.8 5.5e-09 -0.53 0.23 0.59 FALSE
9 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 6.0 -5.7 1.0e-08 -0.79 0.03 0.90 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 6.0 5.8 5.8e-09 0.73 0.01 0.99 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 -5.0 -6.8 8.8e-12 -0.55 0.02 0.94 TRUE
12 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 5.7 5.7 1.1e-08 0.75 0.02 0.72 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 -4.7 -5.8 6.0e-09 -0.60 0.21 0.40 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 -4.9 -6.1 1.1e-09 -0.55 0.16 0.76 FALSE