[Hub]/) : Traits : Cardiovascular Disease : ← →

chr4:17,104,059-18,507,692

Best TWAS P=8.78e-12 · Best GWAS P=3.12e-10 conditioned to 0.00256

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	-5.0	-6.8	8.8e-12	-0.55	0.02	0.94	TRUE
1	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	5.9	-6.8	1.3e-11	-0.69	0.05	0.77	FALSE
4	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	6.0	-6.7	2.0e-11	-0.69	0.03	0.67	FALSE
6	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	-4.7	-6.2	5.3e-10	-0.66	0.05	0.59	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	-4.9	-6.1	1.1e-09	-0.55	0.16	0.76	FALSE
8	GTEx	Thyroid	DCAF16	0.11	0.02	lasso	5	0.03	2.3e-03	-4.7	-5.8	5.5e-09	-0.53	0.23	0.59	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	6.0	5.8	5.8e-09	0.73	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCAF16	0.04	0.04	blup	31	0.04	2.2e-05	-4.7	-5.8	6.0e-09	-0.60	0.21	0.40	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	6.0	-5.7	1.0e-08	-0.79	0.03	0.90	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	5.7	5.7	1.1e-08	0.75	0.02	0.72	FALSE
3	GTEx	Breast Mammary Tissue	DCAF16	0.12	0.08	lasso	4	0.10	6.4e-06	-4.4	-5.7	1.5e-08	-0.45	0.10	0.76	FALSE
2	GTEx	Artery Tibial	DCAF16	0.16	0.16	lasso	5	0.13	1.5e-10	-5.0	-5.4	6.1e-08	-0.31	0.94	0.06	FALSE
7	GTEx	Stomach	DCAF16	0.21	0.04	lasso	6	0.02	5.6e-02	-4.9	-5.3	1.5e-07	-0.23	0.19	0.06	FALSE
5	GTEx	Nerve Tibial	DCAF16	0.16	0.14	lasso	3	0.14	2.8e-10	-4.7	-5.2	2.2e-07	-0.32	0.97	0.03	FALSE