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Cardiovascular Disease
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chr6:124,741,508-127,355,237
Best TWAS P=2.54e-10 · Best GWAS P=2.21e-30 conditioned to 2.76e-24
125M
125.5M
126M
126.5M
127M
127.5M
0
5
10
15
20
25
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Vagina
CENPW
0.24
-0.01
lasso
8
-0.01
7.9e-01
4.6
6.3
2.5e-10
0.32
0.03
0.23
TRUE
2
GTEx
Thyroid
HEY2
0.22
0.24
lasso
6
0.23
1.0e-17
-5.1
-5.5
3.6e-08
0.03
0.01
0.98
TRUE
4
ROSMAP
Brain Pre-frontal Cortex
HEY2
0.10
0.12
enet
15
0.13
9.8e-17
5.2
-5.3
1.1e-07
0.05
0.01
0.99
FALSE
1
GTEx
Artery Coronary
TPD52L1
0.31
-0.01
enet
19
0.05
7.0e-03
-1.1
-5.2
2.2e-07
-0.02
0.03
0.35
FALSE