Best TWAS P=2.54e-10 · Best GWAS P=2.21e-30 conditioned to 2.76e-24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | TPD52L1 | 0.31 | -0.01 | enet | 19 | 0.05 | 7.0e-03 | -1.1 | -5.2 | 2.2e-07 | -0.02 | 0.03 | 0.35 | FALSE |
| 2 | GTEx | Thyroid | HEY2 | 0.22 | 0.24 | lasso | 6 | 0.23 | 1.0e-17 | -5.1 | -5.5 | 3.6e-08 | 0.03 | 0.01 | 0.98 | TRUE |
| 3 | GTEx | Vagina | CENPW | 0.24 | -0.01 | lasso | 8 | -0.01 | 7.9e-01 | 4.6 | 6.3 | 2.5e-10 | 0.32 | 0.03 | 0.23 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | HEY2 | 0.10 | 0.12 | enet | 15 | 0.13 | 9.8e-17 | 5.2 | -5.3 | 1.1e-07 | 0.05 | 0.01 | 0.99 | FALSE |