Best TWAS P=8.9e-09 · Best GWAS P=2.42e-10 conditioned to 0.000323
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Caudate basal ganglia | GATAD1 | 0.21 | 0.09 | lasso | 4 | 0.08 | 0.00231 | -3.9 | 5.2 | 1.9e-07 | -0.62 | 0.08 | 0.30 | FALSE |
2 | GTEx | Muscle Skeletal | GATAD1 | 0.05 | 0.00 | enet | 13 | 0.01 | 0.02430 | -4.1 | 5.8 | 8.9e-09 | -0.60 | 0.09 | 0.82 | TRUE |
3 | YFS | Blood | GATAD1 | 0.01 | 0.01 | blup | 297 | 0.01 | 0.00051 | -4.4 | 5.7 | 1.2e-08 | -0.59 | 0.68 | 0.16 | FALSE |