TWAS
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Traits
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Cardiovascular Disease
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chr7:91,380,845-92,776,699
Best TWAS P=8.9e-09 · Best GWAS P=2.42e-10 conditioned to 0.000323
91.4M
91.6M
91.8M
92M
92.2M
92.4M
92.6M
92.8M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Muscle Skeletal
GATAD1
0.05
0.00
enet
13
0.01
0.02430
-4.1
5.8
8.9e-09
-0.60
0.09
0.82
TRUE
3
YFS
Blood
GATAD1
0.01
0.01
blup
297
0.01
0.00051
-4.4
5.7
1.2e-08
-0.59
0.68
0.16
FALSE
1
GTEx
Brain Caudate basal ganglia
GATAD1
0.21
0.09
lasso
4
0.08
0.00231
-3.9
5.2
1.9e-07
-0.62
0.08
0.30
FALSE