[Hub]/) : Traits : Cardiovascular Disease : ← →

chr1:62,207,254-63,844,736

Best TWAS P=1.75e-08 · Best GWAS P=4.8e-09 conditioned to 0.0835

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	ROSMAP	Brain Pre-frontal Cortex	DOCK7	0.06	0.06	lasso	6	0.06	3.7e-08	-5.7	-5.6	1.8e-08	0.92	0.06	0.94	TRUE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	DOCK7	0.04	0.01	enet	3	0.02	3.0e-03	-5.7	5.5	3.7e-08	-0.98	0.04	0.73	FALSE
3	GTEx	Skin Not Sun Exposed Suprapubic	DOCK7	0.17	0.01	lasso	2	0.00	2.5e-01	-5.5	5.5	3.8e-08	-0.97	0.06	0.62	FALSE
6	GTEx	Whole Blood	USP1	0.05	0.02	lasso	1	0.02	1.0e-02	-5.5	5.5	3.9e-08	-0.97	0.05	0.90	FALSE
4	GTEx	Skin Sun Exposed Lower leg	DOCK7	0.09	0.10	lasso	3	0.10	2.7e-08	-5.5	5.5	4.0e-08	-0.97	0.05	0.95	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	DOCK7	0.01	0.01	blup	85	0.01	1.1e-03	-5.7	5.5	4.3e-08	-0.98	0.04	0.93	FALSE
12	The Cancer Genome Atlas	Thyroid Carcinoma	DOCK7	0.05	0.03	blup	86	0.02	1.6e-03	-4.5	5.5	4.8e-08	-0.92	0.05	0.91	FALSE
8	YFS	Blood	DOCK7	0.05	0.04	lasso	8	0.05	1.3e-14	-5.5	5.3	1.1e-07	-0.95	0.06	0.94	FALSE
10	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DOCK7	0.06	0.07	blup	86	0.07	1.0e-04	-5.5	5.3	1.1e-07	-0.96	0.05	0.94	FALSE
1	GTEx	Artery Aorta	DOCK7	0.14	0.08	lasso	4	0.09	1.2e-05	-5.6	5.3	1.4e-07	-0.90	0.06	0.93	FALSE
2	GTEx	Artery Tibial	DOCK7	0.07	0.07	enet	20	0.07	3.5e-06	-5.5	5.2	2.2e-07	-0.95	0.08	0.92	FALSE
5	GTEx	Whole Blood	DOCK7	0.06	0.00	lasso	6	0.00	1.6e-01	-5.3	5.2	2.6e-07	-0.96	0.09	0.83	FALSE