[Hub]/) : Traits : Cardiovascular Disease : ← →

chr1:62,207,254-63,844,736

Best TWAS P=1.75e-08 · Best GWAS P=4.8e-09 conditioned to 0.0835

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta DOCK7 0.14 0.08 lasso 4 0.09 1.2e-05 -5.6 5.3 1.4e-07 -0.90 0.06 0.93 FALSE
2 GTEx Artery Tibial DOCK7 0.07 0.07 enet 20 0.07 3.5e-06 -5.5 5.2 2.2e-07 -0.95 0.08 0.92 FALSE
3 GTEx Skin Not Sun Exposed Suprapubic DOCK7 0.17 0.01 lasso 2 0.00 2.5e-01 -5.5 5.5 3.8e-08 -0.97 0.06 0.62 FALSE
4 GTEx Skin Sun Exposed Lower leg DOCK7 0.09 0.10 lasso 3 0.10 2.7e-08 -5.5 5.5 4.0e-08 -0.97 0.05 0.95 FALSE
5 GTEx Whole Blood DOCK7 0.06 0.00 lasso 6 0.00 1.6e-01 -5.3 5.2 2.6e-07 -0.96 0.09 0.83 FALSE
6 GTEx Whole Blood USP1 0.05 0.02 lasso 1 0.02 1.0e-02 -5.5 5.5 3.9e-08 -0.97 0.05 0.90 FALSE
7 ROSMAP Brain Pre-frontal Cortex DOCK7 0.06 0.06 lasso 6 0.06 3.7e-08 -5.7 -5.6 1.8e-08 0.92 0.06 0.94 TRUE
8 YFS Blood DOCK7 0.05 0.04 lasso 8 0.05 1.3e-14 -5.5 5.3 1.1e-07 -0.95 0.06 0.94 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma DOCK7 0.01 0.01 blup 85 0.01 1.1e-03 -5.7 5.5 4.3e-08 -0.98 0.04 0.93 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DOCK7 0.06 0.07 blup 86 0.07 1.0e-04 -5.5 5.3 1.1e-07 -0.96 0.05 0.94 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma DOCK7 0.04 0.01 enet 3 0.02 3.0e-03 -5.7 5.5 3.7e-08 -0.98 0.04 0.73 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma DOCK7 0.05 0.03 blup 86 0.02 1.6e-03 -4.5 5.5 4.8e-08 -0.92 0.05 0.91 FALSE