Best TWAS P=1.17e-13 · Best GWAS P=8.33e-16 conditioned to 6.54e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | CPN2 | 0.07 | 0.08 | lasso | 7 | 0.08 | 3.1e-07 | -4.9 | -5.5 | 4.9e-08 | 0.34 | 1.00 | 0.00 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CPN2 | 0.10 | 0.16 | enet | 11 | 0.17 | 3.1e-34 | -5.5 | -5.7 | 9.7e-09 | 0.38 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LRRC15 | 0.02 | 0.02 | blup | 65 | 0.01 | 5.9e-04 | -6.6 | 7.4 | 1.2e-13 | -0.70 | 0.10 | 0.64 | TRUE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CPN2 | 0.10 | 0.11 | lasso | 8 | 0.15 | 1.6e-16 | -5.8 | -5.8 | 6.4e-09 | 0.41 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | CPN2 | 0.09 | 0.04 | blup | 63 | 0.05 | 4.1e-04 | -7.3 | -5.9 | 4.7e-09 | 0.65 | 0.05 | 0.72 | FALSE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | CPN2 | 0.14 | 0.12 | lasso | 2 | 0.13 | 4.1e-06 | -4.9 | -5.5 | 2.9e-08 | 0.35 | 0.68 | 0.10 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | CPN2 | 0.03 | 0.01 | enet | 6 | 0.02 | 1.1e-02 | -5.8 | -5.9 | 3.2e-09 | 0.46 | 0.20 | 0.09 | FALSE |