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chr3:190,347,989-191,808,091

Best TWAS P=5.21e-15 · Best GWAS P=5.44e-14 conditioned to 1.92e-13

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CCDC50	0.13	0.08	bslmm	481	0.08	3.4e-10	7.2	-6.0	1.6e-09	0.07	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	CCDC50	0.20	0.16	enet	26	0.16	3.2e-13	7.3	-7.1	9.2e-13	0.07	0.01	0.99	FALSE
3	GTEx	Adipose Visceral Omentum	CCDC50	0.20	0.14	lasso	5	0.14	7.3e-08	7.3	-7.4	1.6e-13	0.04	0.01	0.99	FALSE
4	GTEx	Artery Aorta	CCDC50	0.34	0.23	lasso	15	0.32	3.7e-18	7.1	-7.7	1.0e-14	0.03	0.01	0.99	FALSE
5	GTEx	Artery Coronary	CCDC50	0.35	0.12	lasso	7	0.15	1.2e-05	6.3	-7.2	7.1e-13	0.04	0.02	0.98	FALSE
6	GTEx	Artery Tibial	CCDC50	0.42	0.42	lasso	6	0.45	9.6e-39	7.1	-7.6	3.9e-14	0.05	0.02	0.98	FALSE
7	GTEx	Breast Mammary Tissue	CCDC50	0.15	0.09	enet	16	0.12	1.1e-06	7.3	-7.5	8.9e-14	0.24	0.01	0.98	FALSE
8	GTEx	Breast Mammary Tissue (Female)	CCDC50	0.14	0.00	lasso	4	0.00	2.9e-01	7.3	-5.7	1.3e-08	0.40	0.04	0.45	FALSE
9	GTEx	Cells Transformed fibroblasts	CCDC50	0.20	0.16	lasso	4	0.23	2.1e-17	5.9	6.5	1.1e-10	-0.04	0.97	0.03	FALSE
10	GTEx	Colon Transverse	CCDC50	0.16	0.11	lasso	5	0.10	2.7e-05	7.3	-7.3	2.0e-13	0.03	0.01	0.98	FALSE
11	GTEx	Esophagus Gastroesophageal Junction	CCDC50	0.22	0.16	enet	11	0.13	2.0e-05	7.3	-6.1	9.7e-10	0.01	0.02	0.98	FALSE
12	GTEx	Esophagus Muscularis	CCDC50	0.29	0.19	lasso	3	0.25	1.4e-15	7.1	-7.6	3.2e-14	0.03	0.03	0.97	FALSE
13	GTEx	Nerve Tibial	CCDC50	0.33	0.20	lasso	9	0.24	4.2e-17	7.1	-7.8	5.2e-15	0.02	0.01	0.99	TRUE
14	GTEx	Ovary	CCDC50	0.56	0.19	lasso	5	0.29	9.3e-08	-2.0	-6.2	7.8e-10	0.08	0.02	0.95	FALSE
15	GTEx	Pancreas	CCDC50	0.34	0.31	enet	22	0.31	1.6e-13	6.5	-6.3	3.4e-10	0.13	0.44	0.56	FALSE
16	GTEx	Thyroid	CCDC50	0.39	0.34	enet	8	0.40	2.2e-32	7.3	-7.2	4.8e-13	0.03	0.01	0.99	FALSE
17	METSIM	Adipose	CCDC50	0.05	0.07	lasso	5	0.06	1.4e-09	5.9	-5.9	3.5e-09	0.03	0.91	0.09	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CCDC50	0.22	0.17	enet	17	0.18	1.6e-10	5.9	-5.5	4.5e-08	0.02	0.92	0.08	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	CCDC50	0.07	0.09	lasso	6	0.08	4.2e-08	5.9	-6.3	2.4e-10	0.04	0.33	0.67	FALSE