Best TWAS P=3.42e-27 · Best GWAS P=2.74e-89 conditioned to 7.33e-83
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ADAMTS3 | 0.10 | 0.1 | lasso | 8 | 0.11 | 1.1e-13 | 6.7 | 10.8 | 3.4e-27 | 0.81 | 0.41 | 0.59 | TRUE |
2 | CommonMind | Brain Pre-frontal Cortex | SLC4A4 | 0.04 | 0.0 | blup | 439 | 0.02 | 9.7e-04 | 2.3 | 5.5 | 2.9e-08 | -0.01 | 0.04 | 0.80 | TRUE |
3 | YFS | Blood | ANKRD17 | 0.01 | 0.0 | bslmm | 348 | 0.00 | 2.0e-02 | 2.0 | 7.0 | 2.6e-12 | 0.45 | 0.08 | 0.20 | FALSE |