TWAS hub - SLC4A4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.044	0.019	0.0062	0.005	0.022	0.016	0.019	0.010	0.077	0.00097	0.00410	0.0019	0.017
2	GTEx	Cells Transformed fibroblasts	0.114	0.047	0.0064	0.009	NA	0.045	NA	0.013	0.065	NA	0.00024	NA	0.033

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Number of treatments/medications taken	6.1	11.0	22.0	0.1	-4.7
Heel T-Score	4.6	36.8	61.2	-3.5	-7.8
Blood White Count	3.9	29.1	57.3	7.6	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	3.7	8.4	14.3	-1.6	-3.8
Mean Putamen Volume	3.6	4.1	8.1	0.4	-2.8
Pulse wave peak to peak time	3.4	4.0	8.0	0.3	2.8
Pulse wave Arterial Stiffness index	3.2	3.7	7.4	-0.1	-2.7
Breastfed as a baby	3.2	4.0	4.0	-2.0	-2.0
Illnesses of father: Heart disease	3.1	4.3	7.3	-2.7	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	2.6	6.0	10.3	-1.3	-3.2
Medication for pain relief, constipation, heartburn	2.6	4.4	8.1	-0.9	2.8
Medication for cholesterol	2.6	4.0	4.3	2.1	1.9
Hypertension (Self-reported)	2.5	7.0	12.6	-1.1	-3.5
Vascular/heart problems diagnosed by doctor	2.5	6.8	13.0	0.8	3.6
Cardiovascular Disease	2.4	8.1	14.7	-1.2	-3.8
Medication: Simvastatin	2.4	3.5	6.2	-0.9	-2.5
Hypothyroidism/myxoedema (self-reported)	2.4	4.8	9.0	-0.7	-3.0
Medication for cholesterol, blood pressure or diabetes	2.3	3.8	7.5	-0.3	2.7
Illness, injury, bereavement, stress in last 2 years	2.2	2.6	5.0	2.2	-0.5
Medication for hormone replacement therapy	2.1	2.3	3.8	-0.9	-2.0
Father’s age at death	2.1	2.9	5.3	0.7	2.3
Medication: Ibuprofen	2.1	2.5	4.1	-0.9	-2.0
Family relationship satisfaction	2.1	2.6	4.1	-1.1	2.0
Number of self-reported non-cancer illnesses	2.1	3.6	6.0	-1.1	-2.4
Diabetes (father)	2.0	2.5	4.9	0.4	2.2
Number of children fathered	2.0	2.2	3.8	-0.8	-1.9
Migraine (self-reported)	2.0	2.5	3.2	-1.3	-1.8
High blood pressure	1.9	5.2	9.7	-0.8	-3.1
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.2	2.5	-1.6	-1.4
Pulse wave reflection index	1.9	2.4	3.1	-1.3	-1.8
Ever taken oral contraceptive pill	1.9	2.2	2.4	1.6	1.4
Exposure to tobacco smoke at home	1.8	2.1	2.4	-1.6	1.3
Osteoarthritis (self-reported)	1.8	2.3	4.5	-0.2	-2.1
Eye problems/disorders: Diabetes related eye disease	1.7	1.9	3.0	1.7	0.9
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.8	5.3	2.3	-0.4
Qualifications: NVQ or HND or HNC or equivalent	1.7	2.1	4.1	0.2	-2.0
Taking other prescription medications	1.6	2.5	4.7	0.6	-2.2
Prospective memory result	1.6	2.0	3.9	2.0	-0.2
Medication: Blood pressure	1.6	2.9	5.7	0.3	-2.4
Supplements: Vitamin C	1.6	1.9	3.6	-1.9	0.5
Mood swings	1.6	2.9	5.8	2.4	-0.1
Qualifications: nursing, teaching	1.6	2.5	4.2	-1.0	2.0
Commuting to job workplace: Public transport	1.6	1.9	3.8	-0.1	1.9
Ulcerative Colitis (UC)	1.5	2.8	5.5	-0.2	2.4
HbA1C	1.4	1.6	3.1	1.8	0.2
Ulcerative Colitis	1.4	2.1	4.1	-0.4	2.0
Hypothyroidism (self reported)	1.4	3.1	5.7	-0.8	-2.4
Medication: Atenolol	1.4	1.7	1.8	1.3	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	2.3	1.5	-0.8
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	2.8	0.8	-1.7
Tense / ‘highly strung’	1.3	2.2	3.2	1.8	-1.1
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	2.4	-1.6	-1.3
Number of full brothers	1.3	1.6	3.0	-0.4	1.7
Mineral and other dietary supplements	1.3	1.8	2.1	1.4	1.2
Tinnitus: Yes, now most or all of the time	1.3	1.5	2.4	-1.6	-0.7
Pain type(s) experienced in last month: Hip pain	1.3	1.6	1.9	1.2	-1.4
Supplements: Calcium	1.3	1.4	2.6	-1.6	0.5
Worry (Nagel 2018)	1.2	2.6	4.6	0.7	-2.1
Crohns Disease (2012)	1.2	2.0	2.5	1.6	-1.2
Diverticular disease/diverticulitis (self-reported)	1.2	1.5	1.9	-1.0	-1.4
Eye problems/disorders: None of the above	1.2	1.4	1.7	-1.1	1.3
Neck or shoulder pain in last month	1.2	1.8	3.4	0.4	-1.8
Medication: Allopurinol	1.2	1.6	3.3	1.8	0.0
Knee pain experienced in last month	1.2	1.9	3.2	-1.8	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.6	4.2	2.1	1.0
Diabetes diagnosed by doctor	1.2	2.0	2.2	1.5	1.4
Commuting to job workplace: Walk	1.2	1.3	2.6	-1.6	0.0
Irritability	1.2	2.1	4.2	2.0	-0.2
Ever had prostate specific antigen (PSA) test	1.2	1.4	1.8	1.4	-1.0
Fractured/broken bones in last 5 years	1.2	1.5	3.0	1.7	0.2
Diastolic blood pressure, automated reading	1.2	3.7	6.5	-1.0	-2.5
Pack years of smoking	1.2	1.7	2.7	0.9	-1.6
Rheumatoid Arthritis	1.1	1.4	2.8	-0.4	-1.7
Height	1.1	20.7	30.8	5.5	3.2
Ever used hormone-replacement therapy (HRT)	1.1	1.4	2.7	-1.6	-0.4
Pack years adult smoking proportion	1.1	1.7	2.3	1.0	-1.5
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	2.4	-1.5	0.4
Happiness	1.1	1.4	2.6	-0.3	1.6
Medication: Cholesterol lowering	1.1	1.6	3.0	0.5	-1.7
Depression (self-reported)	1.1	1.3	2.0	-1.4	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	1.6	1.3	1.0
Comparative height size at age 10	1.1	6.2	7.9	2.1	2.8
Commuting to job workplace: Car/motor vehicle	1.1	1.3	2.1	0.8	-1.4
Ever had bowel cancer screening	1.1	1.2	1.7	-0.9	-1.3
Medication: Gliclazide	1.1	1.3	2.5	-0.2	1.6
Bipolar Disorder (2011)	1.0	1.0	1.7	-1.3	-0.5
Lung FEV1/FVC ratio	1.0	4.8	5.2	-2.1	-2.3
Medication: Co-codamol	1.0	1.2	1.4	1.2	-1.0
Average weekly fortified wine intake	1.0	1.2	2.3	-0.3	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	2.5	1.6	-0.5
Medication: Levothyroxine sodium	1.0	1.7	2.4	-1.0	-1.5
Nervous feelings	1.0	1.9	2.7	-1.0	-1.7
Medication: Ramipril	1.0	1.2	1.7	0.9	-1.3
Alcohol intake versus 10 years previously	1.0	1.5	2.9	-0.2	1.7
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	2.3	-0.3	-1.5
Medication: Amlodipine	1.0	1.4	2.1	-1.4	-0.8
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.4	-1.6	-0.4
Pulse rate, automated reading	1.0	3.3	4.1	1.6	-2.0
Wears glasses or contact lenses	1.0	1.1	1.6	0.8	-1.3
High cholesterol (Self-reported)	1.0	1.8	3.4	-0.3	-1.8
Medication: Bendroflumethiazide	1.0	1.5	2.5	-1.6	-0.7
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	1.8	1.3	0.9
Depressed Affect (Nagel 2018)	0.9	1.8	2.0	1.3	-1.4
Schizophrenia (2014)	0.9	1.9	3.6	0.6	1.9
Relative age of first facial hair	0.9	1.9	2.2	1.5	1.3
Hearing difficulty/problems with background noise	0.9	1.4	2.5	0.6	-1.6
Forced vital capacity (FVC)	0.9	3.5	4.9	2.2	1.4
Worrier / anxious feelings	0.9	1.7	3.3	0.2	-1.8
Chronic bronchitis/emphysema (mother)	0.9	1.0	1.7	-0.5	-1.3
Medication: Aspirin	0.9	1.2	2.0	0.6	-1.4
Medication: Lisinopril	0.9	1.2	2.0	1.4	-0.6
Depression (Nagel 2018)	0.8	1.1	1.3	1.1	-1.0
Neuroticism (Nagel 2018)	0.8	1.8	2.0	1.3	-1.4
LDL Cholesterol	0.8	1.3	1.9	-0.8	1.4
Average weekly spirits intake	0.8	1.0	1.6	1.3	0.6
Severe depression (siblings)	0.8	0.9	1.7	-1.3	-0.3
Impedance of leg (right)	0.8	4.0	6.8	2.6	1.1
Qualifications: None of the above	0.8	1.6	2.9	1.7	0.6
Mouth/teeth dental problems	0.8	1.3	1.3	-1.1	1.1
Illnesses of mother	0.8	0.9	1.6	0.5	1.3
Standing height	0.8	8.4	11.8	3.4	2.2
Average weekly red wine intake	0.8	1.1	2.2	-1.5	-0.1
Friendships satisfaction	0.8	1.0	2.0	-1.4	0.3
Back pain experienced in last month	0.8	1.2	2.1	-0.4	-1.5
Asthma (self-reported)	0.8	1.6	3.0	0.5	-1.7
Medication: Blood pressure	0.8	1.5	1.6	-1.2	-1.2
Supplements: Fish oil (including cod liver oil)	0.8	1.1	2.0	-1.4	-0.3
Illnesses of father: High blood pressure	0.8	1.0	1.8	-0.3	-1.3
Schizophrenia (2018)	0.7	1.5	3.0	0.1	1.7
Irritable Bowel Disease (IBD)	0.7	1.8	3.2	0.6	1.8
Neuroticism (2016)	0.7	1.0	1.5	1.2	-0.7
Blood Eosinophil Count	0.7	5.5	10.8	3.3	-0.4
Blood Platelet Count	0.7	7.6	13.5	3.7	-1.3
Maternal smoking around birth	0.7	1.0	1.3	1.1	0.9
Sitting height	0.7	4.9	7.1	2.7	1.7
Impedance of leg (left)	0.7	3.6	6.2	2.5	1.0
Number of incorrect matches in round	0.7	1.1	1.8	-0.6	1.3
Neuroticism score	0.7	1.4	2.8	1.7	-0.2
Falls in the last year	0.7	0.9	1.5	1.2	-0.6
Noisy workplace	0.7	0.9	1.3	0.7	1.2
Mouth/teeth dental problems: Dentures	0.7	1.1	1.3	1.1	-1.0
Asthma	0.7	1.5	2.8	0.3	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	1.6	0.8	-1.3
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.3	-0.7	-1.1
Number of full sisters	0.7	0.8	1.5	-0.3	-1.2
Age at last live birth	0.7	1.0	1.4	-1.2	-0.8
Breast cancer (self-reported)	0.7	0.8	1.5	0.4	1.2
Mother’s age at death	0.7	0.9	1.2	-0.7	-1.1
Basal cell carcinoma (self-reported)	0.7	0.9	1.6	0.4	-1.3
Prostate Cancer	0.6	0.8	1.0	-0.8	1.0
HDL Cholesterol	0.6	1.1	1.8	0.5	-1.4
Triglycerides	0.6	1.0	1.4	1.2	0.8
Medication: Metformin	0.6	0.8	1.6	1.2	0.2
Diabetes (mother)	0.6	0.8	1.0	0.8	1.0
Age when periods started (menarche)	0.6	1.5	2.8	1.7	-0.4
Serious illness, injury or assault to yourself	0.6	0.7	0.9	0.9	0.7
Had other major operations	0.6	0.7	1.0	0.6	1.0
Trunk fat-free mass	0.6	3.2	3.8	1.9	1.6
Qualifications: A levels/AS levels or equivalent	0.6	1.3	1.6	-1.3	1.0
Worry too long after embarrassment	0.6	0.9	1.9	-0.1	1.4
Angina (self-reported)	0.6	0.7	1.2	-0.5	-1.1
Heart disease (mother)	0.6	0.7	0.8	-0.7	-0.9
Chest pain or discomfort	0.6	0.9	1.2	-0.8	-1.1
Medication: Aspirin	0.6	0.8	1.3	0.6	-1.2
Miserableness	0.6	1.1	2.0	0.4	-1.4
Eye problems/disorders: Glaucoma	0.6	0.7	1.3	-0.3	-1.1
Average weekly beer plus cider intake	0.6	0.8	1.2	1.1	-0.7
Arm predicted mass (left)	0.6	3.3	4.2	2.0	1.6
Alzheimer’s Disease (in mother)	0.5	0.6	1.1	0.3	-1.1
Ovarian Cancer	0.5	0.6	0.7	0.7	0.9
Body Mass Index (BMI) (2010)	0.5	0.7	1.4	1.2	-0.2
Neuroticism	0.5	1.3	2.2	1.5	-0.7
Hand grip strength (left)	0.5	1.4	2.2	0.8	1.5
Hair/balding pattern: Pattern 2	0.5	0.6	0.9	-0.9	0.5
Medication: Lansoprazole	0.5	0.6	1.0	0.4	-1.0
Trunk predicted mass	0.5	3.0	3.8	1.9	1.5
Blood clot in the leg (DVT)	0.5	0.7	1.1	1.1	0.5
Gout (self-reported)	0.5	0.7	0.7	0.8	0.8
Forced vital capacity (FVC), Best measure	0.5	2.0	2.2	1.3	1.5
Arm fat-free mass (right)	0.5	2.6	4.5	2.1	0.9
Arm predicted mass (right)	0.5	2.5	4.1	2.0	0.9
Overall health rating	0.5	1.1	1.2	1.1	1.0
Guilty feelings	0.5	0.8	1.6	1.3	0.1
Arm fat-free mass (left)	0.5	2.6	3.7	1.9	1.2
Ever depressed for a whole week	0.5	0.7	0.7	0.9	0.8
Unable to work because of sickness or disability	0.5	0.6	1.0	1.0	-0.5
Commuting to job workplace: Cycle	0.5	0.6	1.0	-1.0	0.3
Bipolar Disorder or Schizophrenia	0.4	1.0	2.0	-0.0	1.4
Primary Biliary Cirrhosis	0.4	0.6	1.0	-0.3	1.0
Blood Red Count	0.4	3.7	5.7	-1.3	-2.4
Sensitivity / hurt feelings	0.4	0.7	1.0	1.0	0.5
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	1.1	1.0	0.3
Systolic blood pressure, automated reading	0.4	1.1	1.6	-0.7	-1.3
Angina	0.4	0.5	0.8	-0.4	-0.9
Townsend deprivation index at recruitment	0.4	0.5	1.1	-0.2	1.0
Current tobacco smoking	0.4	0.7	1.4	-0.2	1.2
High blood pressure (mother)	0.4	0.5	0.7	-0.9	0.6
Alcohol usually taken with meals	0.4	0.6	1.0	1.0	0.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.5	0.6	0.7
Financial difficulties in last 2 years	0.4	0.6	0.9	-0.5	1.0
Pain all over the body in last month	0.4	0.4	0.7	0.3	-0.9
Diabetes (self-reported)	0.4	0.7	0.8	0.9	0.7
Pulse rate	0.4	0.7	1.4	1.2	-0.1
Ever highly irritable/argumentative for 2 days	0.4	0.4	0.8	0.9	-0.1
Headache pain in last month	0.4	0.6	1.2	0.1	1.1
Birth weight	0.4	0.8	1.0	-1.0	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.1	-0.2	-1.1
Medication: Omeprazole	0.4	0.4	0.8	0.0	-0.9
Had major operations	0.4	0.5	0.5	0.7	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	0.8	0.9	0.0
Osteoporosis (self-reported)	0.4	0.5	1.0	-0.2	-1.0
Financial situation satisfaction	0.4	0.5	0.5	-0.7	0.7
Medication: Paracetamol	0.4	0.6	1.2	-0.1	-1.1
Number of operations (self-reported)	0.4	0.6	1.1	1.0	-0.4
Alcohol drinker status: Previous	0.4	0.4	0.8	0.9	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	0.4	0.6	0.5
Major Depression (MDD)	0.3	0.4	0.8	-0.9	-0.0
Breast Cancer	0.3	0.8	1.3	1.1	-0.5
Coronary Artery Disease (CAD)	0.3	0.4	0.5	-0.7	0.5
Lupus	0.3	0.4	0.8	-0.9	0.1
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.7	0.1	0.8
Systolic Blood Pressure	0.3	1.5	1.9	-1.1	-1.4
Smoking Status	0.3	0.7	1.4	0.2	1.2
Allergy or Eczema	0.3	0.7	0.9	-0.7	-0.9
Respiratory disease	0.3	0.6	0.8	0.6	-0.9
Type 2 Diabetes (T2D) (2018)	0.3	0.5	0.7	0.8	0.6
Vitamin and mineral supplements	0.3	0.4	0.4	0.6	-0.6
Fed-up feelings	0.3	0.5	0.9	1.0	-0.0
Relative age voice broke	0.3	0.5	0.9	1.0	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.6	0.2	0.8
Supplements: Glucosamine	0.3	0.4	0.7	-0.8	0.2
Time employed in main current job	0.3	0.4	0.6	0.8	-0.4
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	1.6	1.3	0.7
Loud music exposure frequency	0.3	0.4	0.5	0.7	-0.4
Medication: Paracetamol	0.3	0.4	0.8	0.1	-0.9
Leg fat percentage (right)	0.3	1.1	1.5	1.2	-0.9
Wheeze or whistling in the chest in last year	0.3	0.5	1.0	1.0	-0.2
Health satisfaction	0.3	0.4	0.8	0.9	0.2
Illnesses of siblings: Diabetes	0.3	0.4	0.8	0.1	0.9
Whole body fat-free mass	0.3	1.9	2.1	1.4	1.3
Arm fat percentage (left)	0.3	1.1	1.6	-0.8	-1.3
Loneliness, isolation	0.3	0.4	0.8	0.9	-0.2
Long-standing illness, disability or infirmity	0.3	0.5	0.9	0.2	1.0
Illnesses of father: None of the above (group 1)	0.3	0.4	0.6	-0.4	0.8
Smoking status: Current	0.3	0.5	0.9	-0.2	1.0
Whole body water mass	0.3	1.7	1.9	1.4	1.3
Basal metabolic rate	0.3	1.8	2.2	1.5	1.2
Leg fat percentage (left)	0.3	0.9	1.1	1.1	-0.9
Cholesterol lowering medication	0.3	0.5	0.8	-0.9	-0.4
Pain experienced in last month	0.3	0.4	0.8	0.3	0.9
Schizophrenia vs Biploar Disorder	0.2	0.3	0.5	0.4	0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	0.0	-0.7
Crohns Disease (2017)	0.2	0.5	1.1	1.0	0.2
Verbal and Numeric Reasoning (VNR)	0.2	0.4	0.6	0.8	0.5
Chronotype (morning person)	0.2	0.5	0.8	0.9	-0.5
Tanning	0.2	2.4	2.7	1.6	1.5
Hearing difficulty/problems: Yes	0.2	0.4	0.5	0.5	-0.7
Trunk fat percentage	0.2	1.0	1.8	0.4	-1.3
Hand grip strength (right)	0.2	0.6	1.0	0.5	1.0
Qualifications: CSEs or equivalent	0.2	0.3	0.5	-0.7	0.1
Body mass index (BMI)	0.2	0.7	0.8	-0.7	-0.9
Trunk fat mass	0.2	0.9	1.0	1.0	-0.9
Had menopause	0.2	0.2	0.4	0.2	0.6
Arm fat percentage (right)	0.2	1.0	1.0	-1.0	-1.0
Lung cancer (father)	0.2	0.3	0.3	-0.5	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	0.8	0.7	0.9
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.5	0.7	-0.2
Glaucoma (self-reported)	0.2	0.2	0.4	-0.7	-0.1
High blood pressure (siblings)	0.2	0.3	0.5	-0.4	0.7
Body fat percentage	0.2	0.9	1.4	0.6	-1.2
Comparative body size at age 10	0.2	0.6	1.1	-1.1	0.3
Shortness of breath walking on level ground	0.2	0.3	0.5	-0.7	-0.0
Emphysema/chronic bronchitis	0.2	0.2	0.4	0.6	-0.2
Leg fat mass (right)	0.2	0.7	1.3	1.1	-0.3
Suffer from ‘nerves’	0.2	0.3	0.7	0.8	-0.2
Leg pain on walking	0.2	0.2	0.5	0.7	0.0
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.2	0.5	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.7	0.8	-0.3
Average weekly champagne plus white wine intake	0.2	0.3	0.5	0.7	0.3
Hearing aid user	0.2	0.2	0.4	0.6	-0.1
Age started oral contraceptive pill	0.2	0.2	0.4	0.3	0.6
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.2	0.4	-0.5
Heart disease (siblings)	0.2	0.3	0.5	0.0	-0.7
Reaction Time	0.1	0.2	0.3	-0.5	0.4
Age at First Birth	0.1	0.2	0.2	0.4	-0.5
Waist Hip Ratio (WHR)	0.1	0.3	0.4	0.6	0.4
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	-0.1	-0.3
Leg fat-free mass (left)	0.1	0.5	0.7	0.5	0.9
Stomach or abdominal pain in last month	0.1	0.1	0.1	0.3	0.2
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.5	-0.1
Leg predicted mass (left)	0.1	0.5	0.6	0.6	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.3	0.3	0.5
Heart attack	0.1	0.2	0.2	0.4	-0.4
Fluid intelligence score	0.1	0.2	0.2	0.4	-0.4
Illnesses of siblings	0.1	0.2	0.2	0.5	-0.5
Weight	0.1	0.5	1.0	1.0	0.1
Impedance of arm (right)	0.1	0.3	0.6	-0.8	0.0
Hair/balding pattern: Pattern 3	0.1	0.1	0.1	0.1	-0.4
Length of working week for main job	0.1	0.1	0.1	0.3	-0.2
Birth weight of first child	0.1	0.1	0.3	-0.5	0.0
Age at first live birth	0.1	0.2	0.3	-0.6	0.3
Qualifications: College or University degree	0.1	0.5	0.7	0.5	0.8
Mean time to correctly identify matches	0.1	0.2	0.3	0.6	-0.2
Whole body fat mass	0.1	0.4	0.6	0.8	-0.5
Alcohol intake frequency.	0.1	0.1	0.3	-0.0	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.1	0.3	-0.2
Leg fat-free mass (right)	0.1	0.4	0.8	0.2	0.9
Eye problems/disorders: Cataract	0.1	0.1	0.2	0.4	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.2	-0.4	-0.1
Leg predicted mass (right)	0.1	0.3	0.6	0.2	0.8
Ever smoked	0.1	0.2	0.3	-0.4	0.6
Myopia	0.1	0.1	0.1	0.3	0.3
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.2	0.4	-0.5
Impedance of whole body	0.1	0.4	0.7	0.9	-0.2
Leg fat mass (left)	0.1	0.5	0.9	1.0	-0.2
Bipolar Disorder (2018)	0.0	0.0	0.0	-0.2	0.1
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.1	0.2	0.3
Fasting Glucose	0.0	0.0	0.1	-0.3	0.1
BMI	0.0	0.2	0.2	-0.5	-0.4
Lung FVC	0.0	0.3	0.4	0.3	0.7
Hair Pigment	0.0	0.9	1.7	-1.3	-0.4
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.0	0.1	0.0
Supplements: Zinc	0.0	0.0	0.0	0.1	-0.1
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.0	-0.1	0.1
Multivitamins +/- minerals	0.0	0.1	0.1	-0.3	-0.2
Waist circumference	0.0	0.0	0.1	0.2	-0.2
Past tobacco smoking	0.0	0.0	0.1	0.3	0.2
Allergy	0.0	0.1	0.1	-0.2	0.4
Hip circumference	0.0	0.1	0.3	0.1	-0.5
Number of live births	0.0	0.0	0.0	-0.1	-0.1
Impedance of arm (left)	0.0	0.2	0.2	-0.4	-0.5
Arm fat mass (right)	0.0	0.0	0.0	0.1	-0.1
Hair/balding pattern: Pattern 4	0.0	0.1	0.2	-0.4	-0.0
Peak expiratory flow (PEF)	0.0	0.0	0.1	-0.1	0.2
Exposure to tobacco smoke outside home	0.0	0.0	0.0	-0.2	-0.2
Medication: Seretide 50 evohaler	0.0	0.0	0.1	0.3	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.0	-0.1	-0.1
Smoking status: Previous	0.0	0.1	0.1	0.2	-0.3
Arm fat mass (left)	0.0	0.2	0.3	-0.1	-0.6
Medication: Atorvastatin	0.0	0.0	0.0	0.1	0.0
Alcohol drinker status: Never	0.0	0.0	0.0	0.0	0.0
Risk taking	0.0	0.0	0.0	0.0	-0.1

Hub : Genes

SLC4A4

Models

Trait associations