Best TWAS P=4.57e-08 · Best GWAS P=8.52e-10 conditioned to 0.00265
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | RP1-30M3.5 | 0.22 | 0.14 | lasso | 5 | 0.19 | 1.1e-12 | -5.1 | 5.5 | 4.6e-08 | -0.77 | 0.14 | 0.86 | TRUE |
2 | GTEx | Skin Sun Exposed Lower leg | ACOT13 | 0.22 | 0.08 | lasso | 8 | 0.11 | 1.1e-09 | 3.7 | 5.3 | 1.1e-07 | -0.29 | 0.99 | 0.01 | FALSE |