Best TWAS P=4.58e-53 · Best GWAS P=1.08e-47 conditioned to 0.0057
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | COL11A1 | 0.01 | 0.01 | blup | 156 | 0.01 | 0.0027 | -10.0 | -15.3 | 4.6e-53 | -0.85 | 0.01 | 0.88 | TRUE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | COL11A1 | 0.23 | 0.04 | lasso | 3 | 0.04 | 0.0172 | 4.9 | -6.5 | 9.5e-11 | -0.23 | 0.08 | 0.09 | FALSE |