Best TWAS P=9.09e-10 · Best GWAS P=2.04e-11 conditioned to 2.65e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | PITRM1 | 0.31 | 0.10 | lasso | 5 | 0.15 | 2.7e-09 | -4.7 | -5.2 | 1.6e-07 | 0.04 | 0.89 | 0.11 | FALSE |
| 2 | GTEx | Nerve Tibial | PITRM1 | 0.25 | 0.10 | lasso | 5 | 0.18 | 5.5e-13 | 4.3 | -6.1 | 9.1e-10 | 0.05 | 0.95 | 0.05 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | PITRM1 | 0.28 | 0.08 | enet | 29 | 0.04 | 4.7e-03 | 6.6 | 5.3 | 1.4e-07 | -0.03 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Spleen | PITRM1 | 0.43 | 0.20 | lasso | 2 | 0.27 | 1.1e-07 | -4.7 | -5.6 | 2.1e-08 | 0.04 | 0.10 | 0.78 | FALSE |
| 5 | GTEx | Spleen | PITRM1-AS1 | 0.41 | 0.27 | lasso | 2 | 0.36 | 4.4e-10 | 4.3 | -5.6 | 1.9e-08 | 0.04 | 0.32 | 0.60 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | PITRM1 | 0.07 | 0.00 | blup | 132 | 0.02 | 3.1e-02 | 3.3 | -5.3 | 1.2e-07 | 0.01 | 0.02 | 0.74 | FALSE |