[Hub]/) : Traits : Height : ← →

chr10:4,129,296-6,576,881

Best TWAS P=1.7e-60 · Best GWAS P=6.21e-59 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AKR1C1	0.30	0.16	bslmm	703	0.18	3.5e-21	4.45	8.6	8.9e-18	-0.55	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	AKR1C2	0.31	0.06	bslmm	665	0.16	2.1e-19	1.40	-11.2	4.2e-29	0.74	0.09	0.91	FALSE
3	GTEx	Adipose Subcutaneous	GDI2	0.28	0.16	enet	12	0.16	3.1e-13	-5.54	5.6	2.2e-08	0.01	0.06	0.94	FALSE
4	GTEx	Adipose Visceral Omentum	GDI2	0.16	0.11	lasso	4	0.11	3.9e-06	-6.05	6.3	2.5e-10	0.01	0.03	0.97	TRUE
5	GTEx	Adrenal Gland	AKR1C1	0.33	0.08	enet	11	0.07	1.8e-03	5.68	-6.6	4.1e-11	0.42	0.49	0.04	FALSE
6	GTEx	Artery Aorta	GDI2	0.23	0.13	lasso	5	0.12	6.1e-07	-6.05	6.2	5.0e-10	0.04	0.04	0.95	FALSE
7	GTEx	Artery Tibial	GDI2	0.32	0.20	lasso	6	0.19	6.6e-15	-5.39	5.3	1.4e-07	0.03	0.23	0.77	FALSE
8	GTEx	Artery Tibial	AKR1C2	0.14	0.10	enet	10	0.15	1.2e-11	-16.06	-14.7	6.1e-49	0.94	0.00	1.00	FALSE
9	GTEx	Brain Cerebellar Hemisphere	AKR1C1	0.46	0.14	lasso	4	0.23	1.4e-06	-5.90	12.3	5.6e-35	-0.85	0.01	0.96	FALSE
10	GTEx	Brain Cerebellum	GDI2	0.31	0.14	lasso	4	0.09	1.4e-03	-6.05	5.6	1.8e-08	0.02	0.05	0.85	FALSE
11	GTEx	Brain Cerebellum	AKR1C2	0.27	0.04	enet	12	0.11	4.1e-04	-16.18	-8.9	5.4e-19	0.68	0.01	0.97	FALSE
12	GTEx	Brain Cortex	AKR1C2	0.49	0.10	lasso	11	0.26	1.1e-07	-16.19	-13.4	1.1e-40	0.85	0.01	0.98	FALSE
13	GTEx	Brain Hippocampus	AKR1C2	0.35	0.13	lasso	9	0.16	1.3e-04	-7.71	-6.8	1.2e-11	0.49	0.07	0.78	FALSE
14	GTEx	Breast Mammary Tissue	GDI2	0.21	0.14	lasso	2	0.12	6.9e-07	-6.05	6.0	2.0e-09	0.03	0.05	0.95	FALSE
15	GTEx	Breast Mammary Tissue (Female)	GDI2	0.26	0.02	lasso	2	0.05	1.7e-02	-6.05	6.1	1.3e-09	0.03	0.04	0.70	FALSE
16	GTEx	Cells Transformed fibroblasts	AKR1C2	0.28	0.23	lasso	6	0.21	1.9e-15	-16.19	-16.4	1.7e-60	1.00	0.00	1.00	TRUE
17	GTEx	Esophagus Muscularis	GDI2	0.18	0.10	lasso	6	0.12	5.5e-08	-5.05	6.0	1.9e-09	0.01	0.08	0.92	FALSE
18	GTEx	Esophagus Muscularis	AKR1C2	0.30	0.21	lasso	2	0.19	8.5e-12	-16.19	-16.2	4.4e-59	1.00	0.00	1.00	FALSE
19	GTEx	Heart Atrial Appendage	AKR1C2	0.28	0.37	lasso	3	0.29	1.2e-13	-16.06	-16.1	3.5e-58	0.98	0.00	1.00	FALSE
20	GTEx	Lung	GDI2	0.19	0.10	lasso	4	0.09	2.8e-07	-5.39	5.3	8.9e-08	0.02	0.07	0.93	FALSE
21	GTEx	Muscle Skeletal	AKR1C2	0.11	0.03	enet	9	0.05	2.0e-05	-2.14	8.5	1.9e-17	-0.55	0.06	0.83	FALSE
22	GTEx	Muscle Skeletal	AKR1E2	0.12	0.02	lasso	4	0.01	2.2e-02	-5.66	6.0	2.4e-09	-0.42	0.16	0.07	FALSE
23	GTEx	Nerve Tibial	GDI2	0.14	0.08	lasso	5	0.08	3.1e-06	-5.39	5.9	3.4e-09	0.02	0.05	0.95	FALSE
24	GTEx	Ovary	AKR1C3	0.35	0.20	lasso	9	0.22	3.9e-06	-16.19	-14.9	3.2e-50	0.91	0.00	0.97	FALSE
25	GTEx	Pancreas	GDI2	0.30	0.23	lasso	4	0.20	4.9e-09	-6.05	6.1	1.3e-09	0.03	0.03	0.97	FALSE
26	GTEx	Skin Not Sun Exposed Suprapubic	GDI2	0.15	0.10	lasso	2	0.08	5.6e-05	-5.54	5.5	3.3e-08	0.01	0.07	0.92	FALSE
27	GTEx	Skin Sun Exposed Lower leg	AKR1C2	0.17	0.18	lasso	2	0.18	4.0e-15	-16.18	-16.2	6.6e-59	1.00	0.00	1.00	FALSE
28	GTEx	Testis	AKR1C2	0.44	0.36	lasso	4	0.36	8.5e-17	-16.19	-16.0	1.3e-57	1.00	0.00	1.00	FALSE
29	GTEx	Testis	AKR1C1	0.28	0.04	enet	39	0.07	3.7e-04	-16.02	11.1	1.2e-28	-0.62	0.01	0.94	FALSE
30	GTEx	Thyroid	GDI2	0.12	0.11	lasso	2	0.11	1.5e-08	-6.05	6.1	1.1e-09	0.03	0.02	0.98	FALSE
31	METSIM	Adipose	AKR1C2	0.06	0.00	blup	656	0.02	1.3e-03	3.43	-6.2	7.4e-10	0.30	0.11	0.14	FALSE
32	NTR	Blood	GDI2	0.04	0.02	lasso	3	0.02	1.6e-07	-6.05	5.9	3.7e-09	0.03	0.03	0.97	FALSE
33	ROSMAP	Brain Pre-frontal Cortex	AKR1C2	0.56	0.40	enet	28	0.46	1.0e-65	-16.19	-14.9	4.8e-50	0.93	0.00	1.00	FALSE
34	ROSMAP	Brain Pre-frontal Cortex	AKR1C1	0.39	0.28	lasso	6	0.32	9.1e-42	4.55	9.0	1.9e-19	-0.61	1.00	0.00	FALSE
35	ROSMAP	Brain Pre-frontal Cortex	ASB13	0.38	0.33	enet	21	0.40	3.4e-54	3.11	-5.2	2.4e-07	-0.05	1.00	0.00	FALSE
36	The Cancer Genome Atlas	Breast Invasive Carcinoma	AKR1C1	0.01	0.00	blup	81	0.01	7.5e-03	5.83	-7.1	9.9e-13	0.43	0.03	0.39	FALSE
37	The Cancer Genome Atlas	Breast Invasive Carcinoma	GDI2	0.03	0.01	blup	59	0.02	4.8e-05	-5.72	6.2	4.4e-10	0.02	0.01	0.98	FALSE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AKR1C1	0.07	0.04	enet	10	0.02	1.0e-03	-16.02	14.9	5.5e-50	-0.88	0.00	0.99	FALSE
39	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AKR1C2	0.12	0.11	lasso	6	0.09	1.6e-10	-16.19	-16.2	8.8e-59	1.00	0.00	1.00	FALSE
40	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AKR1E2	0.07	0.02	blup	146	0.05	2.3e-06	0.96	6.3	2.4e-10	-0.47	0.79	0.12	FALSE
41	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	AKR1C1	0.15	0.02	blup	81	0.06	2.0e-04	4.55	9.6	1.4e-21	-0.59	0.00	0.86	FALSE
42	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	AKR1C2	0.29	0.21	lasso	1	0.21	4.7e-12	-16.06	-16.1	4.8e-58	0.98	0.01	0.99	FALSE
43	The Cancer Genome Atlas	Brain Lower Grade Glioma	AKR1C2	0.09	0.05	blup	62	0.05	3.4e-06	-16.02	-14.3	2.3e-46	0.89	0.00	1.00	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	AKR1C2	0.39	0.18	enet	14	0.23	2.5e-23	-16.19	-14.4	8.3e-47	0.85	0.00	1.00	FALSE
45	The Cancer Genome Atlas	Prostate Adenocarcinoma	AKR1E2	0.07	0.01	lasso	4	0.04	6.3e-05	1.82	5.7	1.3e-08	-0.34	0.35	0.05	FALSE
46	The Cancer Genome Atlas	Prostate Adenocarcinoma	GDI2	0.12	0.10	lasso	2	0.09	7.5e-10	-5.39	5.5	3.9e-08	0.03	0.01	0.99	FALSE
47	The Cancer Genome Atlas	Soft Tissue Sarcoma	AKR1C2	0.07	0.04	enet	5	0.06	1.1e-04	-5.90	-11.2	2.7e-29	0.74	0.02	0.78	FALSE
48	The Cancer Genome Atlas	Thyroid Carcinoma	AKR1C1	0.13	0.13	lasso	6	0.13	2.0e-12	5.71	-5.8	7.5e-09	0.34	1.00	0.00	FALSE
49	The Cancer Genome Atlas	Thyroid Carcinoma	AKR1C2	0.09	0.08	lasso	3	0.08	7.2e-08	-16.02	-15.3	1.2e-52	0.90	0.00	1.00	FALSE
50	The Cancer Genome Atlas	Thyroid Carcinoma	ASB13	0.06	0.02	lasso	5	0.02	6.0e-03	5.79	-6.4	1.2e-10	-0.09	0.08	0.52	TRUE
51	The Cancer Genome Atlas	Thyroid Carcinoma	GDI2	0.07	0.06	enet	8	0.06	1.1e-06	-6.05	6.0	2.5e-09	0.03	0.00	1.00	FALSE