Best TWAS P=1.27e-12 · Best GWAS P=7.78e-10 conditioned to 0.0106
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | METAP2 | 0.11 | 0.07 | lasso | 3 | 0.05 | 0.0021 | 6.0 | -6.4 | 1.9e-10 | -0.87 | 0.01 | 0.67 | FALSE |
| 2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | USP44 | 0.11 | 0.03 | blup | 66 | 0.03 | 0.0167 | -3.8 | 7.1 | 1.3e-12 | 0.57 | 0.02 | 0.55 | TRUE |