Best TWAS P=6.96e-13 · Best GWAS P=3.34e-16 conditioned to 3.59e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | BORA | 0.05 | 0.01 | blup | 541 | 0.02 | 3.4e-03 | 7.3 | 5.1 | 2.8e-07 | -0.05 | 0.08 | 0.70 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | PIBF1 | 0.24 | 0.10 | lasso | 6 | 0.13 | 4.2e-10 | -4.3 | 5.1 | 3.1e-07 | -0.10 | 0.95 | 0.02 | FALSE |
| 3 | METSIM | Adipose | KLF5 | 0.03 | 0.03 | lasso | 6 | 0.02 | 7.2e-04 | -4.0 | 5.3 | 1.1e-07 | -0.05 | 0.28 | 0.03 | FALSE |
| 4 | NTR | Blood | C13orf34 | 0.02 | 0.01 | bslmm | 540 | 0.01 | 2.2e-03 | 6.2 | 5.1 | 3.1e-07 | 0.01 | 0.20 | 0.72 | FALSE |
| 5 | YFS | Blood | DIS3 | 0.02 | 0.00 | enet | 14 | 0.01 | 1.4e-03 | 7.3 | 6.6 | 5.1e-11 | -0.03 | 0.28 | 0.51 | FALSE |
| 6 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | C13orf34 | 0.04 | 0.01 | blup | 47 | 0.01 | 7.1e-02 | 7.3 | 6.2 | 4.7e-10 | -0.06 | 0.01 | 0.95 | FALSE |
| 7 | The Cancer Genome Atlas | Colon Adenocarcinoma | PIBF1 | 0.20 | 0.05 | blup | 96 | 0.10 | 2.4e-06 | 7.2 | 6.4 | 1.9e-10 | -0.10 | 0.08 | 0.65 | FALSE |
| 8 | The Cancer Genome Atlas | Stomach Adenocarcinoma | PIBF1 | 0.09 | 0.02 | blup | 96 | 0.05 | 2.1e-04 | 7.1 | 7.2 | 7.0e-13 | -0.07 | 0.06 | 0.39 | TRUE |