Best TWAS P=1.92e-08 · Best GWAS P=4.71e-08 conditioned to 0.000303
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | SPTLC2 | 0.23 | 0.04 | enet | 14 | 0.07 | 1.8e-04 | -3.4 | -5.6 | 1.9e-08 | 0.38 | 0.19 | 0.62 | TRUE |
| 2 | METSIM | Adipose | SPTLC2 | 0.05 | 0.00 | bslmm | 665 | 0.01 | 6.0e-03 | 1.2 | -5.3 | 1.4e-07 | 0.10 | 0.15 | 0.10 | FALSE |
| 3 | NTR | Blood | SPTLC2 | 0.06 | 0.05 | enet | 7 | 0.07 | 9.0e-21 | 3.5 | -5.1 | 3.1e-07 | 0.53 | 0.76 | 0.08 | FALSE |