Best TWAS P=1.19e-13 · Best GWAS P=3.81e-17 conditioned to 4.22e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | THOC1 | 0.13 | 0.04 | enet | 10 | 0.04 | 6.2e-03 | 7.45 | 7.3 | 2.9e-13 | 0.17 | 0.31 | 0.52 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | USP14 | 0.18 | 0.08 | enet | 22 | 0.16 | 1.0e-20 | 7.36 | -6.7 | 2.3e-11 | -0.35 | 0.90 | 0.10 | FALSE |
| 3 | YFS | Blood | COLEC12 | 0.04 | 0.00 | enet | 15 | 0.02 | 4.2e-07 | -0.92 | -6.0 | 2.2e-09 | -0.14 | 0.21 | 0.50 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | THOC1 | 0.04 | 0.02 | blup | 60 | 0.02 | 1.4e-04 | 7.42 | 7.4 | 1.2e-13 | 0.15 | 0.02 | 0.94 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | THOC1 | 0.03 | 0.03 | lasso | 2 | 0.02 | 6.0e-03 | 7.13 | 7.1 | 9.2e-13 | 0.19 | 0.03 | 0.68 | FALSE |