Best TWAS P=6.75e-13 · Best GWAS P=2.99e-22 conditioned to 8.17e-24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | CCNE1 | 0.31 | 0.19 | lasso | 9 | 0.21 | 6.3e-12 | 7.0 | 6.7 | 3.0e-11 | -0.03 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CCNE1 | 0.27 | 0.22 | lasso | 8 | 0.24 | 2.5e-19 | 7.2 | 6.8 | 9.8e-12 | -0.01 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | CCNE1 | 0.03 | 0.02 | blup | 39 | 0.02 | 4.5e-03 | 7.2 | 7.2 | 6.7e-13 | -0.05 | 0.01 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CCNE1 | 0.03 | 0.03 | enet | 5 | 0.03 | 3.2e-04 | 7.2 | -7.0 | 2.3e-12 | 0.01 | 0.01 | 0.98 | FALSE |