Best TWAS P=1.53e-08 · Best GWAS P=5.41e-13 conditioned to 7.98e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | N6AMT1 | 0.33 | 0.37 | bslmm | 477 | 0.37 | 9.5e-48 | -5.1 | 5.7 | 1.5e-08 | 0.14 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Brain Cortex | N6AMT1 | 0.17 | 0.24 | enet | 12 | 0.22 | 1.3e-06 | -5.2 | 5.2 | 2.0e-07 | 0.14 | 0.52 | 0.03 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | LTN1 | 0.10 | 0.05 | lasso | 4 | 0.03 | 8.6e-03 | -4.7 | 5.3 | 1.1e-07 | 0.12 | 0.37 | 0.08 | FALSE |