Best TWAS P=1.44e-38 · Best GWAS P=2.6e-44 conditioned to 3.02e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | ITSN1 | 0.12 | 0.00 | enet | 18 | 0.02 | 5.7e-03 | 3.0 | -5.5 | 4.2e-08 | 0.24 | 0.11 | 0.03 | FALSE |
| 2 | GTEx | Artery Tibial | MRPS6 | 0.10 | 0.04 | enet | 4 | 0.00 | 1.2e-01 | -13.3 | -13.0 | 1.4e-38 | 0.86 | 0.04 | 0.65 | TRUE |
| 3 | GTEx | Whole Blood | C21orf119 | 0.09 | 0.01 | enet | 16 | 0.04 | 1.2e-04 | 5.9 | -5.9 | 2.9e-09 | -0.08 | 0.01 | 0.90 | TRUE |
| 4 | METSIM | Adipose | EVA1C | 0.06 | 0.05 | enet | 18 | 0.04 | 8.2e-07 | 5.3 | -5.2 | 1.9e-07 | -0.07 | 0.12 | 0.87 | FALSE |
| 5 | NTR | Blood | ITSN1 | 0.07 | 0.06 | lasso | 3 | 0.07 | 5.8e-21 | 6.6 | -7.3 | 3.0e-13 | -0.03 | 1.00 | 0.00 | FALSE |
| 6 | YFS | Blood | ITSN1 | 0.14 | 0.11 | bslmm | 527 | 0.12 | 5.8e-38 | 6.6 | -7.5 | 8.6e-14 | -0.03 | 1.00 | 0.00 | TRUE |